The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease

Neurobiology of Aging

Volumn 36, Issue 11, 2015, Pages 2995-3007

  Varnum, Megan M ^a   Kiyota, Tomomi ^b   Ingraham, Kaitlin L ^a   Ikezu, Seiko ^a   Ikezu, Tsuneya ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Adeno associated virus; Alzheimer's disease; CD200; Microglia; Neuroinflammation; Transgenic mouse model

Indexed keywords

ADENOVIRUS VECTOR; AMYLOID PRECURSOR PROTEIN; CD200 ANTIGEN; THIOFLAVINE; AMYLOID BETA PROTEIN; ANTIGENS, CD200; LEUKOCYTE ANTIGEN;

ADENO ASSOCIATED VIRUS; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; GRANULAR CELL; HIPPOCAMPUS; IN VITRO STUDY; MICROGLIA; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN TRANSPORT; ANIMAL; CELL CULTURE; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; STEM CELL; TRANSGENIC MOUSE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIGENS, CD; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MICE, TRANSGENIC; MICROGLIA; NEURAL STEM CELLS; NEUROGENESIS; PHAGOCYTOSIS; STEM CELLS;

EID: 84947043805     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.07.027     Document Type: Article

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