-
1
-
-
0033600301
-
Molecular basis of the neurodegenerative disorders
-
Martin JB (1999) Molecular basis of the neurodegenerative disorders. N Engl J Med 340:1970-1980.
-
(1999)
N Engl J Med
, vol.340
, pp. 1970-1980
-
-
Martin, J.B.1
-
2
-
-
7044238416
-
Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
-
DOI 10.1038/nm1113
-
Forman MS, Trojanowski JQ, Lee VM (2004) Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 10:1055-1063. (Pubitemid 39424865)
-
(2004)
Nature Medicine
, vol.10
, Issue.10
, pp. 1055-1063
-
-
Forman, M.S.1
Trojanowski, J.Q.2
Lee, V.M.-Y.3
-
3
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298:789-791.
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
4
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson MP (2004) Pathways towards and away from Alzheimer's disease. Nature 430:631-639.
-
(2004)
Nature
, vol.430
, pp. 631-639
-
-
Mattson, M.P.1
-
5
-
-
33746310315
-
Alzheimer's disease
-
DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
-
Blennow K, de Leon MJ, Zetterberg H (2006) Alzheimer's disease. Lancet 368:387-403. (Pubitemid 44108123)
-
(2006)
Lancet
, vol.368
, Issue.9533
, pp. 387-403
-
-
Blennow, K.1
De Leon, M.J.2
Zetterberg, H.3
-
6
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer disease-like pathology in the PDAPP mouse
-
DOI 10.1038/22124
-
Schenk D, et al. (1999) Immunization with amyloid-beta attenuates Alzheimerdisease-like pathology in the PDAPP mouse. Nature 400:173-177. (Pubitemid 29327547)
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guldo, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
7
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
DOI 10.1038/35050116
-
Morgan D, et al. (2000) A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408:982-985. (Pubitemid 32101645)
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
Duff, K.7
Jantzen, P.8
DiCarlo, G.9
Wilcock, D.10
Connor, K.11
Hatcher, J.12
Hope, C.13
Gordon, M.14
Arendash, G.W.15
-
8
-
-
0037452779
-
Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology
-
DOI 10.1073/pnas.0436286100
-
Bard F, et al. (2003) Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology. Proc Natl Acad Sci USA 100:2023-2028. (Pubitemid 36254567)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 2023-2028
-
-
Bard, F.1
Barbour, R.2
Cannon, C.3
Carretto, R.4
Fox, M.5
Games, D.6
Guido, T.7
Hoenow, K.8
Hu, K.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, C.13
Lee, M.14
Motter, R.15
Nguyen, M.16
Reed, A.17
Schenk, D.18
Tang, P.19
Vasquez, N.20
Seubert, P.21
Yednock, T.22
more..
-
9
-
-
0038100154
-
Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease
-
DOI 10.1016/S0896-6273(03)00294-0
-
Hock C, et al. (2003) Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease. Neuron 38:547-554. (Pubitemid 36645030)
-
(2003)
Neuron
, vol.38
, Issue.4
, pp. 547-554
-
-
Hock, C.1
Konietzko, U.2
Streffer, J.R.3
Tracy, J.4
Signorell, A.5
Muller-Tillmanns, B.6
Lemke, U.7
Henke, K.8
Moritz, E.9
Garcia, E.10
Wollmer, M.A.11
Umbricht, D.12
De Quervain, D.J.F.13
Hofmann, M.14
Maddalena, A.15
Papassotiropoulos, A.16
Nitsch, R.M.17
-
10
-
-
0036127580
-
Set back to Alzheimer vaccine studies
-
Birmingham K, Frantz S (2002) Set back to Alzheimer vaccine studies. NatMed 8:199-200. (Pubitemid 34250084)
-
(2002)
Nature Medicine
, vol.8
, Issue.3
, pp. 199-200
-
-
Birmingham, K.1
Frantz, S.2
-
11
-
-
0037203825
-
Nerve inflammation halts trial for Alzheimer's drug
-
Check E (2002) Nerve inflammation halts trial for Alzheimer's drug. Nature 415:462.
-
(2002)
Nature
, vol.415
, pp. 462
-
-
Check, E.1
-
12
-
-
79960769590
-
Prevalence of asymptomatic vasogenic edema in pretreatment Alzheimer's disease study cohorts from phase 3 trials of semagacestat and solanezumab
-
Carlson C, et al. (2011) Prevalence of asymptomatic vasogenic edema in pretreatment Alzheimer's disease study cohorts from phase 3 trials of semagacestat and solanezumab. Alzheimers Dement 7:396-401.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 396-401
-
-
Carlson, C.1
-
13
-
-
79959944588
-
γ-secretase inhibitors and modulators for the treatment of Alzheimer's disease: Disappointments and hopes
-
Imbimbo BP, Giardina GA (2011) γ-secretase inhibitors and modulators for the treatment of Alzheimer's disease: Disappointments and hopes. Curr Top Med Chem 11:1555-1570.
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 1555-1570
-
-
Imbimbo, B.P.1
Giardina, G.A.2
-
14
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
DOI 10.1038/nm1239
-
Tuszynski MH, et al. (2005) A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 11:551-555. (Pubitemid 40691288)
-
(2005)
Nature Medicine
, vol.11
, Issue.5
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
Salmon, D.P.4
Sang U, H.5
Bakay, R.6
Patel, P.7
Blesch, A.8
Vahlsing, H.L.9
Ho, G.10
Tong, G.11
Potkin, S.G.12
Fallon, J.13
Hansen, L.14
Mufson, E.J.15
Kordower, J.H.16
Gall, C.17
Conner, J.18
-
15
-
-
62049083420
-
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
-
Nagahara AH, et al. (2009) Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nat Med 15:331-337.
-
(2009)
Nat Med
, vol.15
, pp. 331-337
-
-
Nagahara, A.H.1
-
16
-
-
43849103202
-
Therapeutic potential of CERE-110 (AAV2-NGF): Targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons
-
Bishop KM, et al. (2008) Therapeutic potential of CERE-110 (AAV2-NGF): Targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons. Exp Neurol 211:574-584.
-
(2008)
Exp Neurol
, vol.211
, pp. 574-584
-
-
Bishop, K.M.1
-
17
-
-
27744516865
-
AAV2/5-mediated NGF gene delivery protects septal cholinergic neurons following axotomy
-
DOI 10.1016/j.brainres.2005.08.056, PII S0006899305012795
-
Wu K, et al. (2005) AAV2/5-mediated NGF gene delivery protects septal cholinergic neurons following axotomy. Brain Res 1061:107-113. (Pubitemid 41587918)
-
(2005)
Brain Research
, vol.1061
, Issue.2
, pp. 107-113
-
-
Wu, K.1
Meyer, E.M.2
Bennett, J.A.3
Meyers, C.A.4
Hughes, J.A.5
King, M.A.6
-
18
-
-
67651240342
-
The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain
-
Mudò G, et al. (2009) The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain. J Neural Transm 116:995-1005.
-
(2009)
J Neural Transm
, vol.116
, pp. 995-1005
-
-
Mudò, G.1
-
19
-
-
0141447477
-
Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice
-
Jin K, et al. (2003) Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice. Aging Cell 2:175-183.
-
(2003)
Aging Cell
, vol.2
, pp. 175-183
-
-
Jin, K.1
-
20
-
-
0030809453
-
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain
-
Kuhn HG, Winkler J, Kempermann G, Thal LJ, Gage FH (1997) Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci 17:5820-5829. (Pubitemid 27310497)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.15
, pp. 5820-5829
-
-
Kuhn, H.G.1
Winkler, J.2
Kempermann, G.3
Thal, L.J.4
Gage, F.H.5
-
21
-
-
0030791066
-
In vivo neurogenesis is inhibited by neutralizing antibodies to basic fibroblast growth factor
-
DOI 10.1002/(SICI)1097-4695(199709)33:3<289::AID-NEU7>3.0.CO;2-Y
-
Tao Y, Black IB, DiCicco-Bloom E (1997) In vivo neurogenesis is inhibited by neutralizing antibodies to basic fibroblast growth factor. J Neurobiol 33:289-296. (Pubitemid 27360499)
-
(1997)
Journal of Neurobiology
, vol.33
, Issue.3
, pp. 289-296
-
-
Tao, Y.1
Black, I.B.2
DiCicco-Bloom, E.3
-
22
-
-
27644564717
-
Influence of EGF/bFGF treatment on proliferation, early neurogenesis and infarct volume after transient focal ischemia
-
DOI 10.1016/j.brainres.2005.07.035
-
Baldauf K, Reymann KG (2005) Influence of EGF/bFGF treatment on proliferation, early neurogenesis and infarct volume after transient focal ischemia. Brain Res 1056:158-167. (Pubitemid 41557703)
-
(2005)
Brain Research
, vol.1056
, Issue.2
, pp. 158-167
-
-
Baldauf, K.1
Reymann, K.G.2
-
23
-
-
0344737616
-
Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury
-
DOI 10.1016/S1044-7431(03)00228-8
-
Sapieha PS, Peltier M, Rendahl KG, Manning WC, Di Polo A (2003) Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury. Mol Cell Neurosci 24:656-672. (Pubitemid 37506010)
-
(2003)
Molecular and Cellular Neuroscience
, vol.24
, Issue.3
, pp. 656-672
-
-
Sapieha, P.S.1
Peltier, M.2
Rendahl, K.G.3
Manning, W.C.4
Di, P.A.5
-
24
-
-
19944431910
-
Adeno-associated viruses containing bFGF or BDNF are neuroprotective against excitotoxicity
-
DOI 10.1080/02713680490517872
-
Schuettauf F, et al. (2004) Adeno-associated viruses containing bFGF or BDNF are neuroprotective against excitotoxicity. Curr Eye Res 29:379-386. (Pubitemid 40138377)
-
(2004)
Current Eye Research
, vol.29
, Issue.6
, pp. 379-386
-
-
Schuettauf, F.1
Vorwerk, C.2
Naskar, R.3
Orlin, A.4
Quinto, K.5
Zurakowski, D.6
Dejneka, N.S.7
Klein, R.L.8
Meyer, E.M.9
Bennett, J.10
-
25
-
-
34548507956
-
Creating a neurogenic environment: The role of BDNF and FGF2
-
DOI 10.1016/j.mcn.2007.06.004, PII S1044743107001509
-
Chen K, Henry RA, Hughes SM, Connor B (2007) Creating a neurogenic environment: The role of BDNF and FGF2. Mol Cell Neurosci 36:108-120. (Pubitemid 47379558)
-
(2007)
Molecular and Cellular Neuroscience
, vol.36
, Issue.1
, pp. 108-120
-
-
Chen, K.1
Henry, R.A.2
Hughes, S.M.3
Connor, B.4
-
26
-
-
34249336353
-
Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis
-
DOI 10.1016/j.neurobiolaging.2006.05.036, PII S0197458006001886
-
Chen H, Tung YC, Li B, Iqbal K, Grundke-Iqbal I (2007) Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiol Aging 28:1148-1162. (Pubitemid 46810057)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.8
, pp. 1148-1162
-
-
Chen, H.1
Tung, Y.-C.2
Li, B.3
Iqbal, K.4
Grundke-Iqbal, I.5
-
27
-
-
0027761023
-
Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease
-
DOI 10.1006/exnr.1993.1202
-
Cummings BJ, Su JH, Cotman CW (1993) Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease. Exp Neurol 124:315-325. (Pubitemid 24041779)
-
(1993)
Experimental Neurology
, vol.124
, Issue.2
, pp. 315-325
-
-
Cummings, B.J.1
Su, J.H.2
Cotman, C.W.3
-
28
-
-
77955814637
-
CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice
-
Kiyota T, et al. (2010) CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice. FASEB J 24:3093-3102.
-
(2010)
FASEB J
, vol.24
, pp. 3093-3102
-
-
Kiyota, T.1
-
29
-
-
84863717973
-
AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice
-
10.1038/gt.2011.126
-
Kiyota T, et al. (2011) AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice. Gene Ther, 10.1038/gt.2011.126.
-
(2011)
Gene Ther
-
-
Kiyota, T.1
-
30
-
-
67349276438
-
AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice
-
Kiyota T, et al. (2009) AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice. Mol Ther 17:803-809.
-
(2009)
Mol Ther
, vol.17
, pp. 803-809
-
-
Kiyota, T.1
-
31
-
-
14244255355
-
Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage
-
Wilcock DM, et al. (2004) Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage. J Neuroinflammation 1:24.
-
(2004)
J Neuroinflammation
, vol.1
, pp. 24
-
-
Wilcock, D.M.1
-
32
-
-
0033565402
-
Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor
-
Wagner JP, Black IB, DiCicco-Bloom E (1999) Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor. J Neurosci 19:6006-6016. (Pubitemid 29327934)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.14
, pp. 6006-6016
-
-
Wagner, J.P.1
Black, I.B.2
DiCicco-Bloom, E.3
-
33
-
-
0842330444
-
Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus
-
DOI 10.1111/j.0953-816X.2003.03123.x
-
Rao MS, Shetty AK (2004) Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur J Neurosci 19:234-246. (Pubitemid 38177862)
-
(2004)
European Journal of Neuroscience
, vol.19
, Issue.2
, pp. 234-246
-
-
Rao, M.S.1
Shetty, A.K.2
-
34
-
-
0027380219
-
Correlations between immediate early gene induction and the persistence of long-term potentiation
-
DOI 10.1016/0306-4522(93)90369-Q
-
Abraham WC, et al. (1993) Correlations between immediate early gene induction and the persistence of long-term potentiation. Neuroscience 56:717-727. (Pubitemid 23290584)
-
(1993)
Neuroscience
, vol.56
, Issue.3
, pp. 717-727
-
-
Abraham, W.C.1
Mason, S.E.2
Demmer, J.3
Williams, J.M.4
Richardson, C.L.5
Tate, W.P.6
Lawlor, P.A.7
Dragunow, M.8
-
35
-
-
0027443739
-
Thresholds for synaptic activation of transcription factors in hippocampus: Correlation with long-term enhancement
-
Worley PF, et al. (1993) Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement. J Neurosci 13:4776-4786. (Pubitemid 23326347)
-
(1993)
Journal of Neuroscience
, vol.13
, Issue.11
, pp. 4776-4786
-
-
Worley, P.F.1
Bhat, R.V.2
Baraban, J.M.3
Erickson, C.A.4
McNaughton, B.L.5
Barnes, C.A.6
-
36
-
-
0029556177
-
Tissue plasminogen activator induction in purkinje neurons after cerebellar motor learning
-
Seeds NW, Williams BL, Bickford PC (1995) Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning. Science 270:1992-1994. (Pubitemid 26097189)
-
(1995)
Science
, vol.270
, Issue.5244
, pp. 1992-1994
-
-
Seeds, N.W.1
Williams, B.L.2
Bickford, P.C.3
-
37
-
-
0034736179
-
Fos expression in the rostral thalamic nuclei and associated cortical regions in response to different spatial memory tests
-
Vann SD, Brown MW, Aggleton JP (2000) Fos expression in the rostral thalamic nuclei and associated cortical regions in response to different spatial memory tests. Neuroscience 101:983-991.
-
(2000)
Neuroscience
, vol.101
, pp. 983-991
-
-
Vann, S.D.1
Brown, M.W.2
Aggleton, J.P.3
-
38
-
-
0026919093
-
Immediate-early genes, neuronal plasticity, and memory
-
Robertson HA (1992) Immediate-early genes, neuronal plasticity, and memory. Biochem Cell Biol 70:729-737.
-
(1992)
Biochem Cell Biol
, vol.70
, pp. 729-737
-
-
Robertson, H.A.1
-
39
-
-
0030055163
-
A role for immediate-early transcription factors in learning and memory
-
Dragunow M (1996) A role for immediate-early transcription factors in learning and memory. Behav Genet 26:293-299.
-
(1996)
Behav Genet
, vol.26
, pp. 293-299
-
-
Dragunow, M.1
-
40
-
-
5344241223
-
LTP and LTD: An embarrassment of riches
-
DOI 10.1016/j.neuron.2004.09.012, PII S0896627304006087
-
Malenka RC, Bear MF (2004) LTP and LTD: An embarrassment of riches. Neuron 44:5-21. (Pubitemid 39348827)
-
(2004)
Neuron
, vol.44
, Issue.1
, pp. 5-21
-
-
Malenka, R.C.1
Bear, M.F.2
-
41
-
-
33845898816
-
Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP
-
DOI 10.1523/JNEUROSCI.4180-06.2006
-
Saganich MJ, et al. (2006) Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP. J Neurosci 26:13428-13436. (Pubitemid 46026474)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.52
, pp. 13428-13436
-
-
Saganich, M.J.1
Schroeder, B.E.2
Galvan, V.3
Bredesen, D.E.4
Koo, E.H.5
Heinemann, S.F.6
-
42
-
-
67650539049
-
CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction
-
Kiyota T, et al. (2009) CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction. PLoS ONE 4:e6197.
-
(2009)
PLoS ONE
, vol.4
-
-
Kiyota, T.1
-
43
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
DOI 10.1126/science.274.5284.99
-
Hsiao K, et al. (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99-102. (Pubitemid 26332733)
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
44
-
-
47549107705
-
Cognitive function over time in the Alzheimer's disease anti-inflammatory prevention trial (ADAPT): Results of a randomized, controlled trial of naproxen and celecoxib
-
DOI 10.1001/archneur.2008.65.7.nct70006
-
Martin BK, et al.; ADAPT Research Group (2008) Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): Results of a randomized, controlled trial of naproxen and celecoxib. Arch Neurol 65:896-905. (Pubitemid 352008472)
-
(2008)
Archives of Neurology
, vol.65
, Issue.7
, pp. 896-905
-
-
Martin, B.K.1
Szekely, C.2
Brandt, J.3
Piantadosi, S.4
Breitner, J.C.S.5
Craft, S.6
Evans, D.7
Green, R.8
Mullan, M.9
-
45
-
-
0035868717
-
Neurogenesis in the adult is involved in the formation of trace memories
-
DOI 10.1038/35066584
-
Shors TJ, et al. (2001) Neurogenesis in the adult is involved in the formation of trace memories. Nature 410:372-376. (Pubitemid 32246054)
-
(2001)
Nature
, vol.410
, Issue.6826
, pp. 372-376
-
-
Shors, T.J.1
Miesegaes, G.2
Beylin, A.3
Zhao, M.4
Rydel, T.5
Gould, E.6
-
46
-
-
58549096746
-
Computational influence of adult neurogenesis on memory encoding
-
Aimone JB, Wiles J, Gage FH (2009) Computational influence of adult neurogenesis on memory encoding. Neuron 61:187-202.
-
(2009)
Neuron
, vol.61
, pp. 187-202
-
-
Aimone, J.B.1
Wiles, J.2
Gage, F.H.3
-
47
-
-
35948979698
-
Neural stem cells improve memory in an inducible mouse model of neuronal loss
-
DOI 10.1523/JNEUROSCI.1627-07.2007
-
Yamasaki TR, et al. (2007) Neural stem cells improve memory in an inducible mouse model of neuronal loss. J Neurosci 27:11925-11933. (Pubitemid 350072121)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.44
, pp. 11925-11933
-
-
Yamasaki, T.R.1
Blurton-Jones, M.2
Morrissette, D.A.3
Kitazawa, M.4
Oddo, S.5
LaFerla, F.M.6
-
48
-
-
32544460592
-
Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease
-
DOI 10.1002/cne.20840
-
Donovan MH, et al. (2006) Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J Comp Neurol 495:70-83. (Pubitemid 43238052)
-
(2006)
Journal of Comparative Neurology
, vol.495
, Issue.1
, pp. 70-83
-
-
Donovan, M.H.1
Yazdani, U.2
Norris, R.D.3
Games, D.4
German, D.C.5
Eisch, A.J.6
-
49
-
-
18244391974
-
Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces
-
DOI 10.1016/S0896-6273(01)00523-2
-
Feng R, et al. (2001) Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces. Neuron 32:911-926. (Pubitemid 34024850)
-
(2001)
Neuron
, vol.32
, Issue.5
, pp. 911-926
-
-
Feng, R.1
Rampon, C.2
Tang, Y.-P.3
Shrom, D.4
Jin, J.5
Kyin, M.6
Sopher, B.7
Martin, G.M.8
Kim, S.-H.9
Langdon, R.B.10
Sisodia, S.S.11
Tsien, J.Z.12
-
50
-
-
0042362874
-
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
-
DOI 10.1046/j.1471-4159.2002.01267.x
-
Haughey NJ, et al. (2002) Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem 83:1509-1524. (Pubitemid 35477489)
-
(2002)
Journal of Neurochemistry
, vol.83
, Issue.6
, pp. 1509-1524
-
-
Haughey, N.J.1
Nath, A.2
Chan, S.L.3
Borchard, A.C.4
Rao, M.S.5
Mattson, M.P.6
-
51
-
-
3042751874
-
The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice
-
DOI 10.1016/j.expneurol.2004.04.002, PII S0014488604001335
-
Wen PH, et al. (2004) The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice. Exp Neurol 188:224-237. (Pubitemid 38891583)
-
(2004)
Experimental Neurology
, vol.188
, Issue.2
, pp. 224-237
-
-
Wen, P.H.1
Hof, P.R.2
Chen, X.3
Gluck, K.4
Austin, G.5
Younkin, S.G.6
Younkin, L.H.7
DeGasperi, R.8
Gama, S.M.A.9
Robakis, N.K.10
Haroutunian, V.11
Elder, G.A.12
-
52
-
-
4444269849
-
Sw,Ind) mice
-
DOI 10.1073/pnas.0403678101
-
Jin K, et al. (2004) Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw, Ind) mice. Proc Natl Acad Sci USA 101:13363-13367. (Pubitemid 39209671)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.36
, pp. 13363-13367
-
-
Jin, K.1
Galvan, V.2
Xie, L.3
Mao, X.O.4
Gorostiza, O.F.5
Bredesen, D.E.6
Greenberg, D.A.7
-
53
-
-
77950868172
-
Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease
-
Wang JM, et al. (2010) Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 107:6498-6503.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6498-6503
-
-
Wang, J.M.1
-
54
-
-
0036709228
-
Phagocytotic removal of apoptotic, inflammatory lymphocytes in the central nervous system by microglia and its functional implications
-
DOI 10.1016/S0165-5728(02)00212-6, PII S0165572802002126
-
Magnus T, Chan A, Savill J, Toyka KV, Gold R (2002) Phagocytotic removal of apoptotic, inflammatory lymphocytes in the central nervous system by microglia and its functional implications. J Neuroimmunol 130:1-9. (Pubitemid 35239988)
-
(2002)
Journal of Neuroimmunology
, vol.130
, Issue.1-2
, pp. 1-9
-
-
Magnus, T.1
Chan, A.2
Savill, J.3
Toyka, K.V.4
Gold, R.5
-
55
-
-
49249116020
-
Behavior of neural stem cells in the Alzheimer brain
-
Waldau B, Shetty AK (2008) Behavior of neural stem cells in the Alzheimer brain. Cell Mol Life Sci 65:2372-2384.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2372-2384
-
-
Waldau, B.1
Shetty, A.K.2
-
56
-
-
0031029569
-
FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells
-
DOI 10.1016/S0896-6273(01)80048-9
-
Qian X, Davis AA, Goderie SK, Temple S (1997) FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells. Neuron 18:81-93. (Pubitemid 27053832)
-
(1997)
Neuron
, vol.18
, Issue.1
, pp. 81-93
-
-
Qian, X.1
Davis, A.A.2
Goderie, S.K.3
Temple, S.4
-
57
-
-
0029997013
-
Nuclear localization of functional FGF receptor 1 in human astrocytes suggests a novel mechanism for growth factor action
-
DOI 10.1016/0169-328X(96)00010-1
-
Stachowiak MK, Maher PA, Joy A, Mordechai E, Stachowiak EK (1996) Nuclear localization of functional FGF receptor 1 in human astrocytes suggests a novel mechanism for growth factor action. Brain Res Mol Brain Res 38:161-165. (Pubitemid 26159205)
-
(1996)
Molecular Brain Research
, vol.38
, Issue.1
, pp. 161-165
-
-
Stachowiak, M.K.1
Maher, P.A.2
Joy, A.3
Mordechai, E.4
Stachowiak, E.K.5
-
58
-
-
37249065138
-
Integrative nuclear signaling in cell development - A role for FGF receptor-1
-
DOI 10.1089/dna.2007.0664
-
Stachowiak MK, Maher PA, Stachowiak EK (2007) Integrative nuclear signaling in cell development - a role for FGF receptor-1. DNA Cell Biol 26:811-826. (Pubitemid 350274413)
-
(2007)
DNA and Cell Biology
, vol.26
, Issue.12
, pp. 811-826
-
-
Stachowiak, M.K.1
Maher, P.A.2
Stachowiak, E.K.3
-
59
-
-
65649127721
-
Fibroblast growth factor receptor-1 (FGFR1) nuclear dynamics reveal a novel mechanism in transcription control
-
Dunham-Ems SM, et al. (2009) Fibroblast growth factor receptor-1 (FGFR1) nuclear dynamics reveal a novel mechanism in transcription control. Mol Biol Cell 20:2401-2412.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2401-2412
-
-
Dunham-Ems, S.M.1
-
60
-
-
0037347399
-
cAMP-induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor-1 (FGFR1)
-
DOI 10.1046/j.1471-4159.2003.01624.x
-
Stachowiak EK, Fang X, Myers J, Dunham S, Stachowiak MK (2003) cAMP-induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor-1 (FGFR1). J Neurochem 84:1296-1312. (Pubitemid 36343596)
-
(2003)
Journal of Neurochemistry
, vol.84
, Issue.6
, pp. 1296-1312
-
-
Stachowiak, E.K.1
Fang, X.2
Myers, J.3
Dunham, S.4
Stachowiak, M.K.5
-
61
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
DOI 10.1038/383710a0
-
Duff K, et al. (1996) Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature 383:710-713. (Pubitemid 26360645)
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
62
-
-
0036428742
-
Measurements of vector-derived neurotrophic factor and green fluorescent protein levels in the brain
-
DOI 10.1016/S1046-2023(02)00234-7, PII S1046202302002347
-
Klein RL, et al. (2002) Measurements of vector-derived neurotrophic factor and green fluorescent protein levels in the brain. Methods 28:286-292. (Pubitemid 35341093)
-
(2002)
Methods
, vol.28
, Issue.2
, pp. 286-292
-
-
Klein, R.L.1
Hamby, M.E.2
Sonntag, C.F.3
Millard, W.J.4
King, M.A.5
Meyer, E.M.6
-
63
-
-
0032924185
-
Gene therapy vectors based on adeno-associated virus type 1
-
Xiao W, et al. (1999) Gene therapy vectors based on adeno-associated virus type 1. J Virol 73:3994-4003. (Pubitemid 29189844)
-
(1999)
Journal of Virology
, vol.73
, Issue.5
, pp. 3994-4003
-
-
Xiao, W.1
Chirmule, N.2
Berta, S.C.3
McCullough, B.4
Gao, G.5
Wilson, J.M.6
-
64
-
-
0031104792
-
Gene transfer by adeno-associated virus vectors into the central nervous system
-
DOI 10.1006/exnr.1996.6396
-
Xiao X, Li J, McCown TJ, Samulski RJ (1997) Gene transfer by adeno-associated virus vectors into the central nervous system. Exp Neurol 144:113-124. (Pubitemid 27149611)
-
(1997)
Experimental Neurology
, vol.144
, Issue.1
, pp. 113-124
-
-
Xiao, X.1
Li, J.2
McCown, T.J.3
Samulski, R.J.4
-
65
-
-
17844375420
-
Overexpression of monocyte chemotactic protein-1/ CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition
-
Yamamoto M, et al. (2005) Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition. Am J Pathol 166:1475-1485. (Pubitemid 40586517)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.5
, pp. 1475-1485
-
-
Yamamoto, M.1
Horiba, M.2
Buescher, J.L.3
Huang, D.4
Gendelman, H.E.5
Ransohoff, R.M.6
Ikezu, T.7
-
66
-
-
33947512432
-
Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice
-
DOI 10.2353/ajpath.2007.060378
-
Yamamoto M, et al. (2007) Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice. Am J Pathol 170:680-692. (Pubitemid 47339404)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.2
, pp. 680-692
-
-
Yamamoto, M.1
Kiyota, T.2
Horiba, M.3
Buescher, J.L.4
Walsh, S.M.5
Gendelman, H.E.6
Ikezu, T.7
-
67
-
-
0037426575
-
Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis
-
DOI 10.1016/S0306-4522(02)00925-9
-
Anderson ER, et al. (2003) Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis. Neuroscience 118:359-369. (Pubitemid 36423251)
-
(2003)
Neuroscience
, vol.118
, Issue.2
, pp. 359-369
-
-
Anderson, E.R.1
Boyle, J.2
Zink, W.E.3
Persidsky, Y.4
Gendelman, H.E.5
Xiong, H.6
-
68
-
-
4143125610
-
Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis
-
DOI 10.1523/JNEUROSCI.1933-04.2004
-
Anderson ER, Gendelman HE, Xiong H (2004) Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis. J Neurosci 24:7194-7198. (Pubitemid 39096385)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.32
, pp. 7194-7198
-
-
Anderson, E.R.1
Gendelman, H.E.2
Xiong, H.3
-
69
-
-
58149379158
-
Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tautubulin kinase 1
-
Sato S, et al. (2008) Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tautubulin kinase 1. J Neurosci 28:14511-14521.
-
(2008)
J Neurosci
, vol.28
, pp. 14511-14521
-
-
Sato, S.1
-
70
-
-
79959568671
-
HIV-1 reduces Abeta-degrading enzymatic activities in primary human mononuclear phagocytes
-
Lan X, et al. (2011) HIV-1 reduces Abeta-degrading enzymatic activities in primary human mononuclear phagocytes. J Immunol 186:6925-6932.
-
(2011)
J Immunol
, vol.186
, pp. 6925-6932
-
-
Lan, X.1
-
71
-
-
78650686603
-
Actin interaction and regulation of cyclin-dependent kinase 5/p35 complex activity
-
Xu J, et al. (2010) Actin interaction and regulation of cyclin-dependent kinase 5/p35 complex activity. J Neurochem 116:192-204.
-
(2010)
J Neurochem
, vol.116
, pp. 192-204
-
-
Xu, J.1
-
72
-
-
77954039898
-
Real-time imaging and quantification of amyloid-beta peptide aggregates by novel quantum-dot nanoprobes
-
Tokuraku K, Marquardt M, Ikezu T (2009) Real-time imaging and quantification of amyloid-beta peptide aggregates by novel quantum-dot nanoprobes. PLoS ONE 4:e8492.
-
(2009)
PLoS ONE
, vol.4
-
-
Tokuraku, K.1
Marquardt, M.2
Ikezu, T.3
|