Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 45, 2015, Pages 13850-13855

  Schreiber, Renate ^a   Hofer, Peter ^a   Taschler, Ulrike ^a   Voshol, Peter J ^b   Rechberger, Gerald N ^a   Kotzbeck, Petra ^a   Jaeger, Doris ^a   Preiss Landl, Karina ^a   Lord, Caleb C ^c   Brown, J Mark ^c   Haemmerle, Guenter ^a   Zimmermann, Robert ^a   Vidal Puig, Antonio ^b   Zechner, Rudolf ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

ATGL; Lipogenesis; Lipolysis; Obesity; PPAR gamma

Indexed keywords

ADIPOSE TRIGLYCERIDE LIPASE; GLUCOSE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; PNPLA2 PROTEIN, MOUSE;

ADAPTATION; ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMYOPATHY; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FAT MASS; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEART MUSCLE CELL; HYPERINSULINEMIA; HYPOPHAGIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LETHALITY; LIPID DIET; LIPOGENESIS; LIPOLYSIS; METABOLIC ADAPTATION; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE EXPANSION; WHITE ADIPOSE TISSUE; ANIMAL; FEEDING BEHAVIOR; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; DIET, HIGH-FAT; FEEDING BEHAVIOR; LIPASE; LIPOLYSIS; MICE; MICE, KNOCKOUT; OBESITY; PHENOTYPE; PPAR GAMMA;

EID: 84946926584     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1516004112     Document Type: Article

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