Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-Dependent upregulation of glutathione synthesis

GLIA

Volumn 63, Issue 9, 2015, Pages 1568-1580

  He, Yan ^a   Jackman, Nicole A ^b   Thorn, Trista L ^a   Vought, Valarie E ^a   Hewett, Sandra J ^a  

^a SYRACUSE UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Central nervous system; Glioprotection; IL 1; Neuroprotection; Oxidative stress

Indexed keywords

BUTHIONINE SULFOXIMINE; FERROUS SULFATE; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 1BETA; TERT BUTYL HYDROPEROXIDE; IL1B PROTEIN, MOUSE; IL1R1 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; RECOMBINANT PROTEIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; BRAIN INJURY; CONTROLLED STUDY; DRUG MECHANISM; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNTHESIS; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CORTEX; C57BL MOUSE; CELL CULTURE; CELL DEATH; CELL SURVIVAL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; ASTROCYTES; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; GLUTATHIONE; INTERLEUKIN-1BETA; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; OXIDANTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RECEPTORS, INTERLEUKIN-1 TYPE I; RECOMBINANT PROTEINS;

EID: 84946912254     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22828     Document Type: Article

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