Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

Neurobiology of Disease

Volumn 85, Issue , 2016, Pages 187-205

  Natunen, Teemu ^a   Takalo, Mari ^a   Kemppainen, Susanna ^a   Leskelä, Stina ^a   Marttinen, Mikael ^a   Kurkinen, Kaisa M A ^a   Pursiheimo, Juha Pekka ^b   Sarajärvi, Timo ^a   Viswanathan, Jayashree ^a   Gabbouj, Sami ^a   Solje, Eino ^a   Tahvanainen, Eveliina ^a   Pirttimäki, Tiina ^a   Kurki, Mitja ^c   Paananen, Jussi ^a   Rauramaa, Tuomas ^a,c   Miettinen, Pasi ^a   Mäkinen, Petra ^a   Leinonen, Ville ^a,c   Soininen, Hilkka ^a,c   Airenne, Kari ^a   Tanzi, Rudolph E ^d,e   Tanila, Heikki ^a   Haapasalo, Annakaisa ^a,c   Hiltunen, Mikko ^a,c   more..

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Institute of Biomedicine   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein (APP); Amyloid (A ); APdE9 transgenic mice; Beta secretase 1 (BACE1); Human brain; Lentivirus; Neuroinflammation; Tau

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE 1; TAU PROTEIN; UBIQUILIN 1; UBIQUITIN; UNCLASSIFIED DRUG; AMYLOID BETA-PROTEIN (1-42); AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; BACE1 PROTEIN, MOUSE; CARRIER PROTEIN; CELL CYCLE PROTEIN; MAPT PROTEIN, HUMAN; PEPTIDE FRAGMENT; SECRETASE; UBQLN1 PROTEIN, HUMAN; UBQLN1 PROTEIN, MOUSE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; EMBRYO; FEMALE; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; LYSOSOME; MALE; MICROGLIA; MOUSE; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; TEMPORAL CORTEX; TRANSGENIC MOUSE; ANIMAL; BRAIN; C57BL MOUSE; CELL SURVIVAL; COCULTURE; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; COCULTURE TECHNIQUES; HUMANS; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; NEURONS; PEPTIDE FRAGMENTS; TAU PROTEINS;

EID: 84946866860     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.11.005     Document Type: Article

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