Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 37, Issue 1, 2013, Pages 217-232

  Natunen, Teemu ^a   Parrado, Antonio R ^b   Helisalmi, Seppo ^a   Pursiheimo, Juha Pekka ^c   Sarajärvi, Timo ^a   Mäkinen, Petra ^a   Kurkinen, Kaisa M A ^a   Mullin, Kristina ^b   Alafuzoff, Irina ^d   Haapasalo, Annakaisa ^a   Bertram, Lars ^e   Soininen, Hilkka ^a,f   Tanzi, Rudolph E ^b   Hiltunen, Mikko ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF TURKU   (Finland)

^d UPPSALA UNIVERSITY   (Sweden)

^e MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^f KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Alzheimer's disease; amyloid ; Braak staging; eukaryotic translation initiation factor 2 ; frozen brain tissue samples; Golgi localized ear containing ADP ribosylation factor binding protein; polymorphism; protein stability; tau protein; secretase

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; BETA SECRETASE 1; BINDING PROTEIN; GGA3 PROTEIN; INITIATION FACTOR 2ALPHA; MESSENGER RNA; SERINE; TAU PROTEIN; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN LEVEL; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; GENE FREQUENCY; GENE LOCATION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFERIOR TEMPORAL CORTEX; NEUROPATHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; RNA, MESSENGER; TEMPORAL LOBE;

EID: 84883139467     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-130104     Document Type: Article

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