메뉴 건너뛰기




Volumn 34, Issue 8, 2014, Pages 2813-2821

Ubiquilin-1 protects cells from oxidative stress and ischemic stroke caused tissue injury in mice

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN ISCHEMIA; DNA, COMPLEMENTARY; FLUORESCEINS; FLUORESCENT DYES; ISCHEMIC ATTACK, TRANSIENT; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; OXIDATIVE STRESS; POSTURAL BALANCE; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; STROKE;

EID: 84894051837     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3541-13.2014     Document Type: Article
Times cited : (56)

References (40)
  • 1
    • 0037628873 scopus 로고    scopus 로고
    • Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases
    • CrossRef Medline
    • Atochin DN, Clark J, Demchenko IT, Moskowitz MA, Huang PL (2003) Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases. Stroke 34:1299-1303. CrossRef Medline
    • (2003) Stroke , vol.34 , pp. 1299-1303
    • Atochin, D.N.1    Clark, J.2    Demchenko, I.T.3    Moskowitz, M.A.4    Huang, P.L.5
  • 3
    • 84856391412 scopus 로고    scopus 로고
    • Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1
    • CrossRef Medline
    • Beverly LJ, Lockwood WW, Shah PP, Erdjument-Bromage H, Varmus H (2012) Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1. Proc Natl Acad Sci U S A 109:E119-126. CrossRef Medline
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Beverly, L.J.1    Lockwood, W.W.2    Shah, P.P.3    Erdjument-Bromage, H.4    Varmus, H.5
  • 6
    • 3342879140 scopus 로고    scopus 로고
    • Identification of ubiquitin-interacting proteins in purified polyglutamine aggregates
    • CrossRef Medline
    • Doi H, Mitsui K, Kurosawa M, Machida Y, Kuroiwa Y, Nukina N (2004) Identification of ubiquitin-interacting proteins in purified polyglutamine aggregates. FEBS Lett 571:171-176. CrossRef Medline
    • (2004) FEBS Lett , vol.571 , pp. 171-176
    • Doi, H.1    Mitsui, K.2    Kurosawa, M.3    Machida, Y.4    Kuroiwa, Y.5    Nukina, N.6
  • 7
    • 84862939340 scopus 로고    scopus 로고
    • Prothymosinalpha interacts with mutant huntingtin and suppresses its cytotoxicity in cell culture
    • CrossRef Medline
    • Dong G, Callegari EA, Gloeckner CJ, Ueffing M, Wang H (2012) Prothymosinalpha interacts with mutant huntingtin and suppresses its cytotoxicity in cell culture. J Biol Chem 287:1279-1289. CrossRef Medline
    • (2012) J Biol Chem , vol.287 , pp. 1279-1289
    • Dong, G.1    Callegari, E.A.2    Gloeckner, C.J.3    Ueffing, M.4    Wang, H.5
  • 8
    • 84865191062 scopus 로고    scopus 로고
    • Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688
    • CrossRef Medline
    • El Ayadi A, Stieren ES, Barral JM, Boehning D (2012) Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688. Proc Natl Acad Sci U S A 109:13416-13421. CrossRef Medline
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 13416-13421
    • El Ayadi, A.1    Stieren, E.S.2    Barral, J.M.3    Boehning, D.4
  • 9
    • 0032440899 scopus 로고    scopus 로고
    • Free radicals as mediators of neuronal injury
    • CrossRef Medline
    • Facchinetti F, Dawson VL, Dawson TM (1998) Free radicals as mediators of neuronal injury. Cell Mol Neurobiol 18:667-682. CrossRef Medline
    • (1998) Cell Mol Neurobiol , vol.18 , pp. 667-682
    • Facchinetti, F.1    Dawson, V.L.2    Dawson, T.M.3
  • 10
    • 1942486364 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin-associated domain-containing protein to promote protein degradation
    • CrossRef Medline
    • Feng P, Scott CW, Cho NH, Nakamura H, Chung YH, Monteiro MJ, Jung JU (2004) Kaposi's sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin-associated domain-containing protein to promote protein degradation. Mol Cell Biol 24:3938-3948. CrossRef Medline
    • (2004) Mol Cell Biol , vol.24 , pp. 3938-3948
    • Feng, P.1    Scott, C.W.2    Cho, N.H.3    Nakamura, H.4    Chung, Y.H.5    Monteiro, M.J.6    Jung, J.U.7
  • 11
    • 36448993027 scopus 로고    scopus 로고
    • Protein aggregation and proteasome dysfunction after brain ischemia
    • CrossRef Medline
    • Ge P, Luo Y, Liu CL, Hu B (2007) Protein aggregation and proteasome dysfunction after brain ischemia. Stroke 38:3230-3236. CrossRef Medline
    • (2007) Stroke , vol.38 , pp. 3230-3236
    • Ge, P.1    Luo, Y.2    Liu, C.L.3    Hu, B.4
  • 12
    • 79952036205 scopus 로고    scopus 로고
    • Protein misfolding and cellular stress: An overview
    • CrossRef Medline
    • Gregersen N, Bross P (2010) Protein misfolding and cellular stress: an overview. Methods Mol Biol 648:3-23. CrossRef Medline
    • (2010) Methods Mol Biol , vol.648 , pp. 3-23
    • Gregersen, N.1    Bross, P.2
  • 13
    • 0035140552 scopus 로고    scopus 로고
    • Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: Apoptosis or necrosis?
    • CrossRef Medline
    • Gujral JS, Bucci TJ, Farhood A, Jaeschke H (2001) Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology 33:397-405. CrossRef Medline
    • (2001) Hepatology , vol.33 , pp. 397-405
    • Gujral, J.S.1    Bucci, T.J.2    Farhood, A.3    Jaeschke, H.4
  • 15
    • 77951236534 scopus 로고    scopus 로고
    • Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS)
    • CrossRef Medline
    • Hanson KA, Kim SH, Wassarman DA, Tibbetts RS (2010) Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS). J Biol Chem 285:11068-11072. CrossRef Medline
    • (2010) J Biol Chem , vol.285 , pp. 11068-11072
    • Hanson, K.A.1    Kim, S.H.2    Wassarman, D.A.3    Tibbetts, R.S.4
  • 16
    • 84864277301 scopus 로고    scopus 로고
    • Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion
    • CrossRef Medline
    • Hochrainer K, Jackman K, Anrather J, Iadecola C (2012) Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion. Stroke 43:2229-2235. CrossRef Medline
    • (2012) Stroke , vol.43 , pp. 2229-2235
    • Hochrainer, K.1    Jackman, K.2    Anrather, J.3    Iadecola, C.4
  • 18
    • 65349122497 scopus 로고    scopus 로고
    • Oxidant stressinduced liver injury in vivo: Role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation
    • CrossRef Medline
    • Hong JY, Lebofsky M, Farhood A, Jaeschke H (2009) Oxidant stressinduced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation. Am J Physiol Gastrointest Liver Physiol 296:G572-581. CrossRef Medline
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Hong, J.Y.1    Lebofsky, M.2    Farhood, A.3    Jaeschke, H.4
  • 19
    • 65549084887 scopus 로고    scopus 로고
    • Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1
    • CrossRef Medline
    • Kim SH, Shi Y, Hanson KA, Williams LM, Sakasai R, Bowler MJ, Tibbetts RS (2009) Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1. J Biol Chem 284:8083-8092. CrossRef Medline
    • (2009) J Biol Chem , vol.284 , pp. 8083-8092
    • Kim, S.H.1    Shi, Y.2    Hanson, K.A.3    Williams, L.M.4    Sakasai, R.5    Bowler, M.J.6    Tibbetts, R.S.7
  • 20
    • 0033636785 scopus 로고    scopus 로고
    • The h PLIC proteins may provide a link between the ubiquitination machinery and the proteasome
    • CrossRef Medline
    • Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM (2000) The h PLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell 6:409-419. CrossRef Medline
    • (2000) Mol Cell , vol.6 , pp. 409-419
    • Kleijnen, M.F.1    Shih, A.H.2    Zhou, P.3    Kumar, S.4    Soccio, R.E.5    Kedersha, N.L.6    Gill, G.7    Howley, P.M.8
  • 21
    • 0037144597 scopus 로고    scopus 로고
    • Role of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stressinduced apoptotic cell death
    • CrossRef Medline
    • Ko HS, Uehara T, Nomura Y (2002) Role of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stressinduced apoptotic cell death. J Biol Chem 277:35386-35392. CrossRef Medline
    • (2002) J Biol Chem , vol.277 , pp. 35386-35392
    • Ko, H.S.1    Uehara, T.2    Nomura, Y.3
  • 22
    • 2442520399 scopus 로고    scopus 로고
    • Ubiquilin interacts with ubiquitylated proteins and proteasome through its ubiquitin-associated and ubiquitin-like domains
    • CrossRef Medline
    • Ko HS, Uehara T, Tsuruma K, Nomura Y (2004) Ubiquilin interacts with ubiquitylated proteins and proteasome through its ubiquitin-associated and ubiquitin-like domains. FEBS Lett 566:110-114. CrossRef Medline
    • (2004) FEBS Lett , vol.566 , pp. 110-114
    • Ko, H.S.1    Uehara, T.2    Tsuruma, K.3    Nomura, Y.4
  • 23
    • 27944439915 scopus 로고    scopus 로고
    • A novel transgenic mouse model reveals deregulation of the ubiquitin-proteasome system in the heart by doxorubicin
    • CrossRef Medline
    • Kumarapeli AR, Horak KM, Glasford JW, Li J, Chen Q, Liu J, Zheng H, Wang X (2005) A novel transgenic mouse model reveals deregulation of the ubiquitin-proteasome system in the heart by doxorubicin. FASEB J 19: 2051-2053. CrossRef Medline
    • (2005) FASEB J , vol.19 , pp. 2051-2053
    • Kumarapeli, A.R.1    Horak, K.M.2    Glasford, J.W.3    Li, J.4    Chen, Q.5    Liu, J.6    Zheng, H.7    Wang, X.8
  • 25
    • 84864650191 scopus 로고    scopus 로고
    • Transient focal cerebral ischemia upregulates immunoproteasomal subunits
    • CrossRef Medline
    • Lü L, Wang H (2012) Transient focal cerebral ischemia upregulates immunoproteasomal subunits. Cell Mol Neurobiol 32:965-970. CrossRef Medline
    • (2012) Cell Mol Neurobiol , vol.32 , pp. 965-970
    • Lü, L.1    Wang, H.2
  • 26
    • 0034645063 scopus 로고    scopus 로고
    • Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation
    • CrossRef Medline
    • Mah AL, Perry G, Smith MA, Monteiro MJ (2000) Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J Cell Biol 151:847-862. CrossRef Medline
    • (2000) J Cell Biol , vol.151 , pp. 847-862
    • Mah, A.L.1    Perry, G.2    Smith, M.A.3    Monteiro, M.J.4
  • 27
    • 0028932259 scopus 로고
    • Overexpression of the rat inducible 70-k D heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury
    • CrossRef Medline
    • Marber MS, Mestril R, Chi SH, Sayen MR, Yellon DM, Dillmann WH (1995) Overexpression of the rat inducible 70-k D heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest 95:1446-1456. CrossRef Medline
    • (1995) J Clin Invest , vol.95 , pp. 1446-1456
    • Marber, M.S.1    Mestril, R.2    Chi, S.H.3    Sayen, M.R.4    Yellon, D.M.5    Dillmann, W.H.6
  • 28
    • 0347480269 scopus 로고    scopus 로고
    • The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gbetagamma
    • CrossRef Medline
    • N'Diaye EN, Brown EJ (2003) The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gbetagamma. J Cell Biol 163:1157-1165. CrossRef Medline
    • (2003) J Cell Biol , vol.163 , pp. 1157-1165
    • N'Diaye, E.N.1    Brown, E.J.2
  • 30
    • 0034714392 scopus 로고    scopus 로고
    • Fluoro-jade B: A high affinity fluorescent marker for the localization of neuronal degeneration
    • CrossRef Medline
    • Schmued LC, Hopkins KJ (2000) Fluoro-jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res 874:123-130. CrossRef Medline
    • (2000) Brain Res , vol.874 , pp. 123-130
    • Schmued, L.C.1    Hopkins, K.J.2
  • 31
    • 39449083733 scopus 로고    scopus 로고
    • Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging
    • CrossRef Medline
    • Slemmer JE, Shacka JJ, Sweeney MI, Weber JT (2008) Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging. Curr Med Chem 15:404-414. CrossRef Medline
    • (2008) Curr Med Chem , vol.15 , pp. 404-414
    • Slemmer, J.E.1    Shacka, J.J.2    Sweeney, M.I.3    Weber, J.T.4
  • 33
    • 79451475816 scopus 로고    scopus 로고
    • Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice
    • CrossRef Medline
    • Su H, Li J, Menon S, Liu J, Kumarapeli AR, Wei N, Wang X (2011) Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice. Circ Res 108:40-50. CrossRef Medline
    • (2011) Circ Res , vol.108 , pp. 40-50
    • Su, H.1    Li, J.2    Menon, S.3    Liu, J.4    Kumarapeli, A.R.5    Wei, N.6    Wang, X.7
  • 34
    • 0020440918 scopus 로고
    • The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes: A study of the implications of oxidative stress in intact cells
    • Medline
    • Thor H, Smith MT, Hartzell P, Bellomo G, Jewell SA, Orrenius S (1982) The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes: a study of the implications of oxidative stress in intact cells. J Biol Chem 257:12419-12425. Medline
    • (1982) J Biol Chem , vol.257 , pp. 12419-12425
    • Thor, H.1    Smith, M.T.2    Hartzell, P.3    Bellomo, G.4    Jewell, S.A.5    Orrenius, S.6
  • 35
    • 84894078043 scopus 로고    scopus 로고
    • Menadione inhibits attenuation of the paracellular permeability of a brain endothelioma cell monolayer by interferon-beta in vitro
    • Voigt K, Kraus J, Oschmann P, Engelhardt B, Clauss M (2004) Menadione inhibits attenuation of the paracellular permeability of a brain endothelioma cell monolayer by interferon-beta in vitro. Akt Neurol 31:P465
    • (2004) Akt Neurol , vol.31
    • Voigt, K.1    Kraus, J.2    Oschmann, P.3    Engelhardt, B.4    Clauss, M.5
  • 36
    • 34447096237 scopus 로고    scopus 로고
    • Ubiquilin overexpression reduces GFPpolyalanine-induced protein aggregates and toxicity
    • CrossRef Medline
    • Wang H, Monteiro MJ (2007a) Ubiquilin overexpression reduces GFPpolyalanine-induced protein aggregates and toxicity. Exp Cell Res 313: 2810-2820. CrossRef Medline
    • (2007) Exp Cell Res , vol.313 , pp. 2810-2820
    • Wang, H.1    Monteiro, M.J.2
  • 37
    • 34447095637 scopus 로고    scopus 로고
    • Ubiquilin interacts and enhances the degradation of expanded-polyglutamine proteins
    • CrossRef Medline
    • Wang H, Monteiro MJ (2007b) Ubiquilin interacts and enhances the degradation of expanded-polyglutamine proteins. Biochem Biophys Res Commun 360:423-427. CrossRef Medline
    • (2007) Biochem Biophys Res Commun , vol.360 , pp. 423-427
    • Wang, H.1    Monteiro, M.J.2
  • 38
    • 33644771265 scopus 로고    scopus 로고
    • Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin
    • CrossRef Medline
    • Wang H, Lim PJ, Yin C, Rieckher M, Vogel BE, Monteiro MJ (2006) Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin. Hum Mol Genet 15:1025-1041. CrossRef Medline
    • (2006) Hum Mol Genet , vol.15 , pp. 1025-1041
    • Wang, H.1    Lim, P.J.2    Yin, C.3    Rieckher, M.4    Vogel, B.E.5    Monteiro, M.J.6
  • 39
    • 77951183159 scopus 로고    scopus 로고
    • An emerging role for Ubiquilin 1 in regulating protein quality control system and in disease pathogenesis
    • Medline
    • Zhang C, Saunders AJ (2009) An emerging role for Ubiquilin 1 in regulating protein quality control system and in disease pathogenesis. Discov Med 8:18-22. Medline
    • (2009) Discov Med , vol.8 , pp. 18-22
    • Zhang, C.1    Saunders, A.J.2
  • 40
    • 0035312367 scopus 로고    scopus 로고
    • Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain
    • CrossRef Medline
    • Zhu Y, Romero MI, Ghosh P, Ye Z, Charnay P, Rushing EJ, Marth JD, Parada LF (2001) Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain. Genes Dev 15:859-876. CrossRef Medline
    • (2001) Genes Dev , vol.15 , pp. 859-876
    • Zhu, Y.1    Romero, M.I.2    Ghosh, P.3    Ye, Z.4    Charnay, P.5    Rushing, E.J.6    Marth, J.D.7    Parada, L.F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.