Ubiquilin 1 modulates amyloid precursor protein trafficking and Aβ secretion

Journal of Biological Chemistry

Volumn 281, Issue 43, 2006, Pages 32240-32253

  Hiltunen, Mikko ^a   Lu, Alice ^a   Thomas, Anne V ^a   Romano, Donna M ^a   Kim, Minji ^a   Jones, Phill B ^a   Xie, Zhongcong ^a   Kounnas, Maria Z ^b   Wagner, Steven L ^b   Berezovska, Oksana ^a   Hyman, Bradley T ^a   Tesco, Giuseppina ^a   Bertram, Lars ^a   Tanzi, Rudolph E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b TorreyPines Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN (APP); FLUORESCENCE RESONANCE; PROTEASOMAL DEGRADATION; PROTEIN TRAFFICKING;

BIOASSAY; BRAIN; CELL CULTURE; DISEASES; DNA; ENERGY TRANSFER; FLUORESCENCE; GENES;

PROTEINS;

ALPHA SECRETASE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE; UBIQUILIN 1; UBIQUITIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CELL MIGRATION; CELL STRAIN HEK293; CYTOPLASM; DOWN REGULATION; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC VARIABILITY; GLIOMA CELL; HUMAN; HUMAN CELL; NERVE CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROCESSING; PROTEIN SECRETION; RNA INTERFERENCE;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BIOTINYLATION; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELLS, CULTURED; DOWN-REGULATION; EXONS; FIBROBLASTS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; NEURONS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

PYRONIA TITHONUS;

EID: 33845942219     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603106200     Document Type: Article

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