-
1
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass CK, Saijo K, Winner B, Marchetto MC, Cage FH, (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140: 918-934.
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Cage, F.H.5
-
2
-
-
77950858637
-
Microglia in neurodegenerative disease
-
Perry VH, Nicoll JAR, Holmes C, (2010) Microglia in neurodegenerative disease. Nat Rev 6: 193-201.
-
(2010)
Nat Rev
, vol.6
, pp. 193-201
-
-
Perry, V.H.1
Nicoll, J.A.R.2
Holmes, C.3
-
3
-
-
57249088999
-
Modeling CNS microglia: the quest to identify predictive models
-
Carson MJ, Crane J, Xie AX, (2008) Modeling CNS microglia: the quest to identify predictive models. Drug Discov Today Dis Models 5: 19-25.
-
(2008)
Drug Discov Today Dis Models
, vol.5
, pp. 19-25
-
-
Carson, M.J.1
Crane, J.2
Xie, A.X.3
-
4
-
-
1642553221
-
Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia
-
Lee H, Kim YO, Kim H, Kim SY, Noh HS, et al. (2003) Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB J 17: 1943-1944.
-
(2003)
FASEB J
, vol.17
, pp. 1943-1944
-
-
Lee, H.1
Kim, Y.O.2
Kim, H.3
Kim, S.Y.4
Noh, H.S.5
-
5
-
-
35948938955
-
Simomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase
-
Qian L, Xu Z, Zhang W, Wilson B, Hong J-S, et al. (2007) Simomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase. J Neuroinflamm 4: 23-36.
-
(2007)
J Neuroinflamm
, vol.4
, pp. 23-36
-
-
Qian, L.1
Xu, Z.2
Zhang, W.3
Wilson, B.4
Hong, J.-S.5
-
6
-
-
46649088909
-
Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia
-
Pan XD, Chen XC, Zhu YG, Zhang J, Huang TW, et al. (2008) Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia. Biochem Pharmacol 76: 362-372.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 362-372
-
-
Pan, X.D.1
Chen, X.C.2
Zhu, Y.G.3
Zhang, J.4
Huang, T.W.5
-
7
-
-
44249090414
-
Anti-inflammatory effects of cathecols in lipopolysaccharide-stimulated microglia cells: inhibition of microglia neurotoxicity
-
Zheng LT, Ryu GM, Kwon bM, Lee WH, Suk K, (2008) Anti-inflammatory effects of cathecols in lipopolysaccharide-stimulated microglia cells: inhibition of microglia neurotoxicity. Eur J Pharmacol 588: 106-113.
-
(2008)
Eur J Pharmacol
, vol.588
, pp. 106-113
-
-
Zheng, L.T.1
Ryu, G.M.2
Kwon, B.M.3
Lee, W.H.4
Suk, K.5
-
8
-
-
58749084091
-
Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation
-
Li Y, Hu X, Liu Y, Bao Y, An L, (2009) Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. Neuropharmacology 56: 580-589.
-
(2009)
Neuropharmacology
, vol.56
, pp. 580-589
-
-
Li, Y.1
Hu, X.2
Liu, Y.3
Bao, Y.4
An, L.5
-
9
-
-
78149435065
-
The myeloid cells of the central nervous system parenchyma
-
Ransohoff RM, Cardona AE, (2010) The myeloid cells of the central nervous system parenchyma. Nature 468: 253-262.
-
(2010)
Nature
, vol.468
, pp. 253-262
-
-
Ransohoff, R.M.1
Cardona, A.E.2
-
10
-
-
0025220976
-
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
-
Lawson LJ, Perry VH, Dri P, Gordon S, (1990) Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39: 151-170.
-
(1990)
Neuroscience
, vol.39
, pp. 151-170
-
-
Lawson, L.J.1
Perry, V.H.2
Dri, P.3
Gordon, S.4
-
11
-
-
0034663061
-
Regional difference in susceptibility in lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia
-
Kim W-G, Mohney RP, Wilson B, Jeohn G-H, Liu B, et al. (2000) Regional difference in susceptibility in lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20: 6309-6316.
-
(2000)
J Neurosci
, vol.20
, pp. 6309-6316
-
-
Kim, W.-G.1
Mohney, R.P.2
Wilson, B.3
Jeohn, G.-H.4
Liu, B.5
-
12
-
-
33646395680
-
Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide
-
Gibbons HM, Dragunov M, (2006) Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide. Brain Res 1084: 1-15.
-
(2006)
Brain Res
, vol.1084
, pp. 1-15
-
-
Gibbons, H.M.1
Dragunov, M.2
-
13
-
-
35448988886
-
Interferon-β is neuroprotective against the toxicity induced by activated microglia
-
Jin S, Kawanokuchi J, Mizuno T, Wang J, Sonobe Y, et al. (2007) Interferon-β is neuroprotective against the toxicity induced by activated microglia. Brain Res 1179: 140-146.
-
(2007)
Brain Res
, vol.1179
, pp. 140-146
-
-
Jin, S.1
Kawanokuchi, J.2
Mizuno, T.3
Wang, J.4
Sonobe, Y.5
-
14
-
-
79959441142
-
Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures
-
Couturier J, Paccalin M, Morel M, Terro F, Milin S, et al. (2011) Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures. J Neuroinflam 8: 72-89.
-
(2011)
J Neuroinflam
, vol.8
, pp. 72-89
-
-
Couturier, J.1
Paccalin, M.2
Morel, M.3
Terro, F.4
Milin, S.5
-
15
-
-
68849123079
-
Accumulation of tau induced in neuritis by microglial proinflammatory mediators
-
Gorlovoy P, Larionov S, Pham TTH, Neumann H, (2009) Accumulation of tau induced in neuritis by microglial proinflammatory mediators. FASEB J 23: 2502-2513.
-
(2009)
FASEB J
, vol.23
, pp. 2502-2513
-
-
Gorlovoy, P.1
Larionov, S.2
Pham, T.T.H.3
Neumann, H.4
-
16
-
-
79954531943
-
Peroxisome proliferator-activated receptor-α agonists protect cortical neurons from inflammatory mediators and improve peroxisomal function
-
Gray E, Ginty M, Kemp K, Scolding N, Wilkins A, (2011) Peroxisome proliferator-activated receptor-α agonists protect cortical neurons from inflammatory mediators and improve peroxisomal function. Eur J Neurosci 33: 1421-1432.
-
(2011)
Eur J Neurosci
, vol.33
, pp. 1421-1432
-
-
Gray, E.1
Ginty, M.2
Kemp, K.3
Scolding, N.4
Wilkins, A.5
-
17
-
-
0025233694
-
Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus
-
Blasi E, Barluzzi R, Bocchini V, Mazzolla R, Bistoni F, (1990) Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J Neuroimmunol 27: 229-237.
-
(1990)
J Neuroimmunol
, vol.27
, pp. 229-237
-
-
Blasi, E.1
Barluzzi, R.2
Bocchini, V.3
Mazzolla, R.4
Bistoni, F.5
-
18
-
-
0344013138
-
High-yield isolation of murine microglia by mild tripsinization
-
Saura J, Tusell JM, Serratosa J, (2003) High-yield isolation of murine microglia by mild tripsinization. Glia 44: 183-189.
-
(2003)
Glia
, vol.44
, pp. 183-189
-
-
Saura, J.1
Tusell, J.M.2
Serratosa, J.3
-
19
-
-
0025269014
-
Development of excitatory aminoacid induced cytotoxicity in cultured neurons
-
Frandsen A, Schousboe A, (1990) Development of excitatory aminoacid induced cytotoxicity in cultured neurons. Int J Dev Neurosci 8: 209-216.
-
(1990)
Int J Dev Neurosci
, vol.8
, pp. 209-216
-
-
Frandsen, A.1
Schousboe, A.2
-
20
-
-
77950166161
-
CCAAT/enhancer binding protein delta in microglial activation
-
Ejarque-Ortiz A, Gresa-Arribas N, Straccia M, Mancera P, Solà C, et al. (2010) CCAAT/enhancer binding protein delta in microglial activation. J Neurosci Res 88: 1113-1123.
-
(2010)
J Neurosci Res
, vol.88
, pp. 1113-1123
-
-
Ejarque-Ortiz, A.1
Gresa-Arribas, N.2
Straccia, M.3
Mancera, P.4
Solà, C.5
-
21
-
-
78651284870
-
Inhibition of CCAAT/enhancer binding protein δ expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects
-
Gresa-Arribas N, Serratosa J, Saura J, Solà C, (2010) Inhibition of CCAAT/enhancer binding protein δ expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects. J Neurochem 115: 526-536.
-
(2010)
J Neurochem
, vol.115
, pp. 526-536
-
-
Gresa-Arribas, N.1
Serratosa, J.2
Saura, J.3
Solà, C.4
-
22
-
-
0034090501
-
High concentrations of extracellular potassium enhance bacterial endotoxin lipopolysaccharide-induced neurotoxicity in glia-neuron mixed cultures
-
Chang RCC, Hudson PM, Wilson BC, Liu B, Abel H, et al. (2000) High concentrations of extracellular potassium enhance bacterial endotoxin lipopolysaccharide-induced neurotoxicity in glia-neuron mixed cultures. Neuroscience 97: 757-764.
-
(2000)
Neuroscience
, vol.97
, pp. 757-764
-
-
Chang, R.C.C.1
Hudson, P.M.2
Wilson, B.C.3
Liu, B.4
Abel, H.5
-
23
-
-
69949140066
-
The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation
-
Henn A, Lund S, Hedtjärn M, Schrattenholz A, Pörzgen P, et al. (2009) The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation. ALTEX 26: 83-94.
-
(2009)
ALTEX
, vol.26
, pp. 83-94
-
-
Henn, A.1
Lund, S.2
Hedtjärn, M.3
Schrattenholz, A.4
Pörzgen, P.5
-
24
-
-
53149124406
-
Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures
-
Horvath R, Nutile-McMenemy N, Alkaitis MS, DeLeo JA, (2008) Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures. J Neurochem 107: 557-569.
-
(2008)
J Neurochem
, vol.107
, pp. 557-569
-
-
Horvath, R.1
Nutile-McMenemy, N.2
Alkaitis, M.S.3
DeLeo, J.A.4
-
25
-
-
43549094448
-
Expression of CXCL4 in microglia in vitro and in vivo and its possible signalling through CXCR3
-
de Jong EK, de Hass AH, Nieske B, van Weering HRJ, Hensens M, et al. (2008) Expression of CXCL4 in microglia in vitro and in vivo and its possible signalling through CXCR3. J Neurochem 105: 1726-1736.
-
(2008)
J Neurochem
, vol.105
, pp. 1726-1736
-
-
de Jong, E.K.1
de Hass, A.H.2
Nieske, B.3
van Weering, H.R.J.4
Hensens, M.5
-
26
-
-
0034032594
-
Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells
-
Ledeboer A, Brevé JJP, Poole S, Tilders FJH, Van Dam, (2000) A-M (2000) Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells. Glia 30: 134-142.
-
(2000)
Glia
, vol.30
, pp. 134-142
-
-
Ledeboer, A.1
Brevé, J.J.P.2
Poole, S.3
Tilders, F.J.H.4
Van Dam, A.-M.5
-
27
-
-
0035136359
-
Actions of exogenous and endogenous IL-10 on glial responses to bacterial LPS/cytokines
-
Molina-Holgado F, Grencis R, Rothwell NJ, (2001) Actions of exogenous and endogenous IL-10 on glial responses to bacterial LPS/cytokines. Glia 33: 97-106.
-
(2001)
Glia
, vol.33
, pp. 97-106
-
-
Molina-Holgado, F.1
Grencis, R.2
Rothwell, N.J.3
-
28
-
-
0035255055
-
IL-4, IL-10 and IL-13 modulate Aβ(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line
-
Szczepanik AM, Funes S, Petko W, Ringheim GE, (2001) IL-4, IL-10 and IL-13 modulate Aβ(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line. J Neuroimmunol 113: 49-62.
-
(2001)
J Neuroimmunol
, vol.113
, pp. 49-62
-
-
Szczepanik, A.M.1
Funes, S.2
Petko, W.3
Ringheim, G.E.4
-
29
-
-
0037209850
-
Inhibition of LPS-induced iNOS and NO synthesis in primary rat microglial cells
-
Lieb K, Engels S, Fiebich BL, (2003) Inhibition of LPS-induced iNOS and NO synthesis in primary rat microglial cells. Neurochem Int 42: 131-137.
-
(2003)
Neurochem Int
, vol.42
, pp. 131-137
-
-
Lieb, K.1
Engels, S.2
Fiebich, B.L.3
-
30
-
-
0032005921
-
Opposite regulation of prostaglandin E2 synthesis by transforming growth factor-β1 and interleukin 10 in activated microglial cultures
-
Minguetti L, Polazzi E, Nicolini A, Levi G, (1998) Opposite regulation of prostaglandin E2 synthesis by transforming growth factor-β1 and interleukin 10 in activated microglial cultures. J Neuroimmunol 82: 31-39.
-
(1998)
J Neuroimmunol
, vol.82
, pp. 31-39
-
-
Minguetti, L.1
Polazzi, E.2
Nicolini, A.3
Levi, G.4
-
31
-
-
33749036329
-
Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase
-
Qian L, Block ML, Wei S-J, Lin C-F, Reece J, et al. (2006) Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase. J Pharmacol Exp Ther 319: 44-52.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 44-52
-
-
Qian, L.1
Block, M.L.2
Wei, S.-J.3
Lin, C.-F.4
Reece, J.5
-
32
-
-
34247157292
-
Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra
-
Arimoto T, Choi DY, Lu X, Liu M, Nguyen XV, et al. (2006) Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra. Neurobiol Aging 28: 894-906.
-
(2006)
Neurobiol Aging
, vol.28
, pp. 894-906
-
-
Arimoto, T.1
Choi, D.Y.2
Lu, X.3
Liu, M.4
Nguyen, X.V.5
-
33
-
-
68949212050
-
Interleukin-10 provides direct trophic support to neurons
-
Zhou Z, Peng X, Insolera R, Fink DJ, Mata M, (2009a) Interleukin-10 provides direct trophic support to neurons. J Neurochem 110: 1617-1627.
-
(2009)
J Neurochem
, vol.110
, pp. 1617-1627
-
-
Zhou, Z.1
Peng, X.2
Insolera, R.3
Fink, D.J.4
Mata, M.5
-
34
-
-
79151475898
-
IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways
-
Sharma S, Yang B, Grotta JC, Aronowski J, Savitz SI, (2011) IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways. Brain Res 1373: 189-194.
-
(2011)
Brain Res
, vol.1373
, pp. 189-194
-
-
Sharma, S.1
Yang, B.2
Grotta, J.C.3
Aronowski, J.4
Savitz, S.I.5
-
35
-
-
70349730234
-
Interleukin-10 promotes neuronal survival following spinal cord injury
-
Zhou Z, Peng X, Insolera R, Fink DJ, Mata M, (2009b) Interleukin-10 promotes neuronal survival following spinal cord injury. Exp Neurol 220: 183-190.
-
(2009)
Exp Neurol
, vol.220
, pp. 183-190
-
-
Zhou, Z.1
Peng, X.2
Insolera, R.3
Fink, D.J.4
Mata, M.5
-
36
-
-
0032865257
-
Neuroprotective effects of IL-10 following excitotoxic spinal cord injury
-
Brewer KL, Bethea JR, Yezierski RP, (1999) Neuroprotective effects of IL-10 following excitotoxic spinal cord injury. Exp Neurol 159: 484-493.
-
(1999)
Exp Neurol
, vol.159
, pp. 484-493
-
-
Brewer, K.L.1
Bethea, J.R.2
Yezierski, R.P.3
-
37
-
-
0037436514
-
Effect of interleukin-10 on neonatal excitotoxic brain lesions in mice
-
Mesples B, Plaisant F, Gressens P, (2003) Effect of interleukin-10 on neonatal excitotoxic brain lesions in mice. Dev Brain Res 141: 25-32.
-
(2003)
Dev Brain Res
, vol.141
, pp. 25-32
-
-
Mesples, B.1
Plaisant, F.2
Gressens, P.3
-
38
-
-
81255168189
-
Interleukin-10 overexpression does not synergize with the neuroprotective action of RGD-containing vectors after postnatal brain excitotoxicity but modulates the main inflammatory cell responses
-
Gonzalez P, Peluffo H, Acarin L, Villaverde A, Gonzalez B, et al. (2012) Interleukin-10 overexpression does not synergize with the neuroprotective action of RGD-containing vectors after postnatal brain excitotoxicity but modulates the main inflammatory cell responses. J Neurosci Res 90: 143-159.
-
(2012)
J Neurosci Res
, vol.90
, pp. 143-159
-
-
Gonzalez, P.1
Peluffo, H.2
Acarin, L.3
Villaverde, A.4
Gonzalez, B.5
-
39
-
-
0037303479
-
Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration
-
Stewart VC, Heales SJ, (2003) Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration. Free Radic Biol Med 34: 287-303.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 287-303
-
-
Stewart, V.C.1
Heales, S.J.2
-
40
-
-
33745039466
-
Nitric oxide, cell bioenergetics and neurodegeneration
-
Moncada S, Bolaños JP, (2006) Nitric oxide, cell bioenergetics and neurodegeneration. J Neurochem 97: 1676-89.
-
(2006)
J Neurochem
, vol.97
, pp. 1676-1689
-
-
Moncada, S.1
Bolaños, J.P.2
-
41
-
-
0036273352
-
Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production
-
Bal-Price A, Matthias A, Brown GC, (2002) Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production. J Neurochem 80: 73-80.
-
(2002)
J Neurochem
, vol.80
, pp. 73-80
-
-
Bal-Price, A.1
Matthias, A.2
Brown, G.C.3
-
42
-
-
0041784698
-
Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
-
Brown GC, Bal-Price A, (2003) Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol Neurobiol 27: 325-355.
-
(2003)
Mol Neurobiol
, vol.27
, pp. 325-355
-
-
Brown, G.C.1
Bal-Price, A.2
|