-
1
-
-
79953293021
-
Chronic pancreatitis
-
Braganza, J. M., Lee, S. H., McCloy, R. F., and McMahon, M. J. (2011) Chronic pancreatitis. Lancet 377, 1184-1197
-
(2011)
Lancet
, vol.377
, pp. 1184-1197
-
-
Braganza, J.M.1
Lee, S.H.2
McCloy, R.F.3
McMahon, M.J.4
-
2
-
-
0035109764
-
Chronic pancreatitis: Diagnosis, classification, and new genetic developments
-
Etemad, B., and Whitcomb, D. C. (2001) Chronic pancreatitis: diagnosis, classification, and new genetic developments. Gastroenterology 120, 682-707
-
(2001)
Gastroenterology
, vol.120
, pp. 682-707
-
-
Etemad, B.1
Whitcomb, D.C.2
-
3
-
-
79955791653
-
Recurrent and relapsing pancreatitis
-
Guda, N. M., Romagnuolo, J., and Freeman, M. L. (2011) Recurrent and relapsing pancreatitis. Curr. Gastroenterol. Rep. 13, 140-149
-
(2011)
Curr. Gastroenterol. Rep.
, vol.13
, pp. 140-149
-
-
Guda, N.M.1
Romagnuolo, J.2
Freeman, M.L.3
-
4
-
-
84863724208
-
Natural history following the first attack of acute pancreatitis
-
Yadav, D., O'Connell, M., and Papachristou, G. I. (2012) Natural history following the first attack of acute pancreatitis. Am. J. Gastroenterol. 107, 1096-1103
-
(2012)
Am. J. Gastroenterol.
, vol.107
, pp. 1096-1103
-
-
Yadav, D.1
O'Connell, M.2
Papachristou, G.I.3
-
5
-
-
81855228093
-
Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis
-
e2212
-
Dawra, R., Sah, R. P., Dudeja, V., Rishi, L., Talukdar, R., G arg, P., and Saluja, A. K. (2011) Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis. Gastroenterology 141, 2210-2217 e2212
-
(2011)
Gastroenterology
, vol.141
, pp. 2210-2217
-
-
Dawra, R.1
Sah, R.P.2
Dudeja, V.3
Rishi, L.4
Talukdar, R.5
Garg, P.6
Saluja, A.K.7
-
6
-
-
84876493374
-
Caeruleininduced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice
-
Sah, R. P., Dudeja, V., Dawra, R. K., and Saluja, A. K. (2013) Caeruleininduced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice. Gastroenterology 144, 1076-1085
-
(2013)
Gastroenterology
, vol.144
, pp. 1076-1085
-
-
Sah, R.P.1
Dudeja, V.2
Dawra, R.K.3
Saluja, A.K.4
-
7
-
-
0036877142
-
The endoplasmic reticulum: A multifunctional signaling organelle
-
Berridge, M. J. (2002) The endoplasmic reticulum: a multifunctional signaling organelle. Cell Calcium 32, 235-249
-
(2002)
Cell Calcium
, vol.32
, pp. 235-249
-
-
Berridge, M.J.1
-
8
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter, P., and Ron, D. (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334, 1081-1086
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
9
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron, D., and Walter, P. (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8, 519 -529
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
10
-
-
77953153048
-
Regulation of basal cellular physiology by the homeostatic unfolded protein response
-
Rutkowski, D. T., and Hegde, R. S. (2010) Regulation of basal cellular physiology by the homeostatic unfolded protein response. J. Cell Biol. 189, 783-794
-
(2010)
J. Cell Biol.
, vol.189
, pp. 783-794
-
-
Rutkowski, D.T.1
Hegde, R.S.2
-
11
-
-
79959897450
-
Endoplasmic reticulum stress and pancreatic beta cell death
-
Fonseca, S. G., Gromada, J., and Urano, F. (2011) Endoplasmic reticulum stress and pancreatic beta cell death. Trends Endocrinol. Metab. 22, 266-274
-
(2011)
Trends Endocrinol. Metab.
, vol.22
, pp. 266-274
-
-
Fonseca, S.G.1
Gromada, J.2
Urano, F.3
-
12
-
-
33846810143
-
Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response
-
Li, B., Gao, B., Ye, L., Han, X., Wang, W., Kong, L., Fang, X., Zeng, Y., Zheng, H., Li, S., and Wu, Z. (2007) Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response. Virus Res. 124, 44 - 49
-
(2007)
Virus Res.
, vol.124
, pp. 44-49
-
-
Li, B.1
Gao, B.2
Ye, L.3
Han, X.4
Wang, W.5
Kong, L.6
Fang, X.7
Zeng, Y.8
Zheng, H.9
Li, S.10
Wu, Z.11
-
13
-
-
84868628378
-
Endoplasmic reticulum stress and hypertension: A new paradigm?
-
Hasty, A. H., and Harrison, D. G. (2012) Endoplasmic reticulum stress and hypertension: a new paradigm? J. Clin. Invest. 122, 3859 -3861
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3859-3861
-
-
Hasty, A.H.1
Harrison, D.G.2
-
14
-
-
79952758037
-
Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: Endoplasmic reticulum stress as a mediator of pathogenesis
-
Dickhout, J. G., Carlisle, R. E., and Austin, R. C. (2011) Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis. Circ. Res. 108, 629-642
-
(2011)
Circ. Res.
, vol.108
, pp. 629-642
-
-
Dickhout, J.G.1
Carlisle, R.E.2
Austin, R.C.3
-
15
-
-
34047136169
-
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
-
Carrasco, D. R., Sukhdeo, K., Protopopova, M., Sinha, R., Enos, M., Carrasco, D. E., Zheng, M., Mani, M., Henderson, J., Pinkus, G. S., Munshi, N., Horner, J., Ivanova, E. V., Protopopov, A., Anderson, K. C., Tonon, G., and DePinho, R. A. (2007) The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell 11, 349-360
-
(2007)
Cancer Cell
, vol.11
, pp. 349-360
-
-
Carrasco, D.R.1
Sukhdeo, K.2
Protopopova, M.3
Sinha, R.4
Enos, M.5
Carrasco, D.E.6
Zheng, M.7
Mani, M.8
Henderson, J.9
Pinkus, G.S.10
Munshi, N.11
Horner, J.12
Ivanova, E.V.13
Protopopov, A.14
Anderson, K.C.15
Tonon, G.16
DePinho, R.A.17
-
16
-
-
84866932320
-
ER stress-induced inflammation: Does it aid or impede disease progression?
-
Garg, A. D., Kaczmarek, A., Krysko, O., Vandenabeele, P., Krysko, D. V., and Agostinis, P. (2012) ER stress-induced inflammation: does it aid or impede disease progression? Trends Mol. Med. 18, 589-598
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 589-598
-
-
Garg, A.D.1
Kaczmarek, A.2
Krysko, O.3
Vandenabeele, P.4
Krysko, D.V.5
Agostinis, P.6
-
17
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil, G. S. (2010) Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140, 900-917
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
18
-
-
84866544628
-
The endoplasmic reticulum stress response in aging and age-related diseases
-
Brown, M. K., and Naidoo, N. (2012) The endoplasmic reticulum stress response in aging and age-related diseases. Front Physiol. 3, 263
-
(2012)
Front Physiol.
, vol.3
, pp. 263
-
-
Brown, M.K.1
Naidoo, N.2
-
19
-
-
74549169836
-
ER stress in Alzheimer's disease: A novel neuronal trigger for inflammation and Alzheimer's pathology
-
Salminen, A., Kauppinen, A., Suuronen, T., Kaarniranta, K., and Ojala, J. (2009) ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. J. Neuroinflammation. 6, 41
-
(2009)
J. Neuroinflammation.
, vol.6
, pp. 41
-
-
Salminen, A.1
Kauppinen, A.2
Suuronen, T.3
Kaarniranta, K.4
Ojala, J.5
-
20
-
-
0017965207
-
Synthesis, intracellular transport and discharge of exportable proteins in the pancreatic acinar cell and other cells
-
Case, R. M. (1978) Synthesis, intracellular transport and discharge of exportable proteins in the pancreatic acinar cell and other cells. Biol. Rev. Camb. Philos. Soc. 53, 211-354
-
(1978)
Biol. Rev. Camb. Philos. Soc.
, vol.53
, pp. 211-354
-
-
Case, R.M.1
-
21
-
-
34447515863
-
Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells. Am.}
-
Kubisch, C. H., and Logsdon, C. D. (2007) Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells. Am.}. Physiol. Gastrointest. Liver Physiol. 292, G1804-G1812
-
(2007)
Physiol. Gastrointest. Liver Physiol.
, vol.292
, pp. G1804-G1812
-
-
Kubisch, C.H.1
Logsdon, C.D.2
-
22
-
-
33745785456
-
Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis
-
Kubisch, C. H., Sans, M. D., Arumugam, T., Ernst, S. A., Williams, J. A., and Logsdon, C. D. (2006) Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis. Am. J. Physiol. Gastrointest. Liver Physiol. 291, G238-G245
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.291
, pp. G238-G245
-
-
Kubisch, C.H.1
Sans, M.D.2
Arumugam, T.3
Ernst, S.A.4
Williams, J.A.5
Logsdon, C.D.6
-
23
-
-
78651295470
-
Misfolded proteins and retinal dystrophies
-
Lin, J. H., and Lavad, M. M. (2010) Misfolded proteins and retinal dystrophies. Adv. Exp. Med. Biol. 664, 115-121
-
(2010)
Adv. Exp. Med. Biol.
, vol.664
, pp. 115-121
-
-
Lin, J.H.1
Lavad, M.M.2
-
24
-
-
84883453911
-
New insights into the pathogenesis of pancreatitis
-
Sah, R. P., Dawra, R. K., and Saluja, A. K. (2013) New insights into the pathogenesis of pancreatitis. Curr. Opin. Gastroenterol. 29, 523-530
-
(2013)
Curr. Opin. Gastroenterol.
, vol.29
, pp. 523-530
-
-
Sah, R.P.1
Dawra, R.K.2
Saluja, A.K.3
-
25
-
-
80052586196
-
Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis
-
Gaiser, S., Daniluk, J., Liu, Y., Tsou, L., Chu, J., Lee, W., Longnecker, D. S., Logsdon, C. D., and Ji, B. (2011) Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis. Gut. 60, 1379-1388
-
(2011)
Gut.
, vol.60
, pp. 1379-1388
-
-
Gaiser, S.1
Daniluk, J.2
Liu, Y.3
Tsou, L.4
Chu, J.5
Lee, W.6
Longnecker, D.S.7
Logsdon, C.D.8
Ji, B.9
-
26
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangle, W., Lerch, M. M., Brandt-Nedelev, B., Roth, W., Ruthenbuerger, M., Reinheckel, T., Domschke, W., Lippert, H., Peters, C., and Deussing, J. (2000) Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J. Clin. Invest. 106, 773-781
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 773-781
-
-
Halangle, W.1
Lerch, M.M.2
Brandt-Nedelev, B.3
Roth, W.4
Ruthenbuerger, M.5
Reinheckel, T.6
Domschke, W.7
Lippert, H.8
Peters, C.9
Deussing, J.10
-
27
-
-
0031867966
-
Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats
-
Hofbauer, B., Saluja, A. K., Lerch, M. M., Bhagat, L., Bhatia, M., Lee, H. S., Frossard, J.L., Adler, G., and Steer, M. L. (1998) Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats. Am. J. Physiol. 275, G352-G362
-
(1998)
Am. J. Physiol.
, vol.275
, pp. G352-G362
-
-
Hofbauer, B.1
Saluja, A.K.2
Lerch, M.M.3
Bhagat, L.4
Bhatia, M.5
Lee, H.S.6
Frossard, J.L.7
Adler, G.8
Steer, M.L.9
-
28
-
-
0032957613
-
Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini
-
Saluja, A. K., Bhagat, L., Lee, H. S., Bhatia, M., Frossard, J. L., and Steer, M. L. (1999) Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini. Am. J. Physiol. 276, G835-G842
-
(1999)
Am. J. Physiol.
, vol.276
, pp. G835-G842
-
-
Saluja, A.K.1
Bhagat, L.2
Lee, H.S.3
Bhatia, M.4
Frossard, J.L.5
Steer, M.L.6
-
29
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida, H., Matsui, T., Yamamoto, A., Okada, T., and Mori, K. (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881-891
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
30
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon, M., Zeng, H., Urano, F., Till, J. H., Hubbard, S. R., Harding, H. P., Clark, S. G., and Ron, D. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415, 92-96
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
31
-
-
62749092531
-
2+ signaling in pancreatic acinar cells: Physiology and pathophysiology
-
Petersen, O. H. (2009) Ca2+ signaling in pancreatic acinar cells: physiology and pathophysiology. Braz J. Med. Biol. Res. 42, 9-16
-
(2009)
Braz J. Med. Biol. Res.
, vol.42
, pp. 9-16
-
-
Petersen, O.H.1
-
32
-
-
39549112572
-
Polarized calcium signaling in exocrine gland cells
-
Petersen, O. H., and Tepikin, A. V. (2008) Polarized calcium signaling in exocrine gland cells. Annu. Rev. Physiol. 70, 273-299
-
(2008)
Annu. Rev. Physiol.
, vol.70
, pp. 273-299
-
-
Petersen, O.H.1
Tepikin, A.V.2
-
33
-
-
24644481459
-
2+-activated ion channels in exocrine acinar cells
-
Petersen, O. H. (2005) Ca2+ signalling and Ca2+-activated ion channels in exocrine acinar cells. Cell Calcium 38, 171-200
-
(2005)
Cell Calcium
, vol.38
, pp. 171-200
-
-
Petersen, O.H.1
-
34
-
-
80051774435
-
Molecular mechanisms of pancreatic injury
-
Sah, R. P., and Saluja, A. (2011) Molecular mechanisms of pancreatic injury. Curr. Opin. Gastroenterol. 27, 444-451
-
(2011)
Curr. Opin. Gastroenterol.
, vol.27
, pp. 444-451
-
-
Sah, R.P.1
Saluja, A.2
-
35
-
-
84865521139
-
Pathogenic mechanisms of acute pancreatitis
-
Sah, R. P., Garg, P., and Saluja, A. K. (2012) Pathogenic mechanisms of acute pancreatitis. Curr. Opin. Gastroenterol. 28, 507-515
-
(2012)
Curr. Opin. Gastroenterol.
, vol.28
, pp. 507-515
-
-
Sah, R.P.1
Garg, P.2
Saluja, A.K.3
-
36
-
-
34250698918
-
Calcium signalling and pancreatic cell death: Apoptosis or necrosis?
-
Griddle, D. N., Gerasimenko, J. V., Baumgartner, H. K., Jaffar, M., Voronina, S., Sutton, R., Petersen, O. H., and Gerasimenko, O. V. (2007) Calcium signalling and pancreatic cell death: apoptosis or necrosis? Cell Death Differ. 14, 1285-1294
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1285-1294
-
-
Griddle, D.N.1
Gerasimenko, J.V.2
Baumgartner, H.K.3
Jaffar, M.4
Voronina, S.5
Sutton, R.6
Petersen, O.H.7
Gerasimenko, O.V.8
-
37
-
-
0028783295
-
Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis
-
Kaiser, A. M., Saluja, A. K., Sengupta, A., Saluja, M., and Steer, M. L. (1995) Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am. J. Physiol. 269, C1295-C1304
-
(1995)
Am. J. Physiol.
, vol.269
, pp. C1295-C1304
-
-
Kaiser, A.M.1
Saluja, A.K.2
Sengupta, A.3
Saluja, M.4
Steer, M.L.5
-
38
-
-
0034741255
-
Relationship between NF-KB and trypsinogen activation in rat pancreas after supramaximal caerulein stimulation
-
Hietaranta, A. J., Saluja, A. K., Bhagat, L., Singh, V. P., Song, A. M., and Steer, M. L. (2001) Relationship between NF-KB and trypsinogen activation in rat pancreas after supramaximal caerulein stimulation. Biochem. Biophys. Res. Commun. 280, 388-395
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 388-395
-
-
Hietaranta, A.J.1
Saluja, A.K.2
Bhagat, L.3
Singh, V.P.4
Song, A.M.5
Steer, M.L.6
-
39
-
-
0032853494
-
2+ and protein kinase C as messengers
-
Tando, Y., Algül, H., Wagner, M., Weidenbach, H., Adler, G., and Schmid, R. M. (1999) Caerulein-induced NF-κB/Rel activation requires both Ca2+ and protein kinase C as messengers. Am. J. Physiol. 277, G678-G686
-
(1999)
Am. J. Physiol.
, vol.277
, pp. G678-G686
-
-
Tando, Y.1
Algül, H.2
Wagner, M.3
Weidenbach, H.4
Adler, G.5
Schmid, R.M.6
-
40
-
-
79955638751
-
Alcohol abuse, endoplasmic reticulum stress and pancreatitis
-
Pandol, S. J., Gorelick, F. S., Gerloff, A., and Lugea, A. (2010) Alcohol abuse, endoplasmic reticulum stress and pancreatitis. Dig Dis. 28, 776-782
-
(2010)
Dig Dis.
, vol.28
, pp. 776-782
-
-
Pandol, S.J.1
Gorelick, F.S.2
Gerloff, A.3
Lugea, A.4
-
41
-
-
63749109353
-
Hereditary pancreatitis caused by mutationinduced misfolding of human cationic trypsinogen: A novel disease mechanism
-
Kereszturi, E., Szmola, R., Kukor, Z., Simon, P., Weiss, F. U., Lerch, M. M., and Sahin-Tóth, M. (2009) Hereditary pancreatitis caused by mutationinduced misfolding of human cationic trypsinogen: a novel disease mechanism. Hum. Mutat. 30, 575-582
-
(2009)
Hum. Mutat.
, vol.30
, pp. 575-582
-
-
Kereszturi, E.1
Szmola, R.2
Kukor, Z.3
Simon, P.4
Weiss, F.U.5
Lerch, M.M.6
Sahin-Tóth, M.7
-
42
-
-
70450248392
-
Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death
-
Kereszturi, E., and Sahin-Tóth, M. (2009) Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death. J. Biol. Chem. 284, 33392-33399
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 33392-33399
-
-
Kereszturi, E.1
Sahin-Tóth, M.2
-
43
-
-
77749318543
-
Pancreatitis-associated chymot- rypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells
-
Szmola, R., and Sahin-Tóth, M. (2010) Pancreatitis-associated chymot- rypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells. Gut. 59, 365-372
-
(2010)
Gut.
, vol.59
, pp. 365-372
-
-
Szmola, R.1
Sahin-Tóth, M.2
-
44
-
-
84891681793
-
Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis
-
Schnúr, A., Beer, S., Witt, H., Hegyi, P., and Sahin-Tóth, M. (2013) Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis. Gut. 63, 337
-
(2013)
Gut.
, vol.63
, pp. 337
-
-
Schnúr, A.1
Beer, S.2
Witt, H.3
Hegyi, P.4
Sahin-Tóth, M.5
-
45
-
-
84885019350
-
Variants in CPA1 are strongly associated with early onset chronic pancreatitis. Nat
-
Witt, H., Beer, S., Rosendahl, J., Chen, J. M., Chandak, G. R., Masamune, A., Bence, M., Szmola, R., Oracz, G., Macek, M., Jr., Bhatia, E., Steigenberger, S., Lasher, D., Bühler, F., Delaporte, C., Tebbing, J., Ludwig, M., Pilsalc, C., Saum, K., Bugert, P., Masson, E., Paliwal, S., Bhaskar, S., Sobczynska-Tomaszewska, A., Bak, D., Balascak, I., Choudhuri, G., Nageshwar Reddy, D., Rao, G. V., Thomas, V., Kume, K., Nakano, E., Kalcuta, Y., Shimosegawa, T., Durko, L., Szabó, A., Schnúr, A., Hegyi, P., Rakonczay, Z., Jr., Pfützer, R., Schneider, A., Groneberg, D. A., Braun, M., Schmidt, H., Witt, U., Friess, H., Algül, H., Landt, O., Schuelke, M., Krüger, R., Wiedenmann, B., Schmidt, F., Zimmer, K. P., Kovacs, P., Stumvoll, M., Blüher, M., Müller, T., Janecke, A., Teich, N., Grützmann, R., Schulz, H. U., Mössner, J., Keim, V., Löhr, M., Férec, C., and Sahin-Tóth, M. (2013) Variants in CPA1 are strongly associated with early onset chronic pancreatitis. Nat. Gewet 45, 1216-1220
-
(2013)
Gewet
, vol.45
, pp. 1216-1220
-
-
Witt, H.1
Beer, S.2
Rosendahl, J.3
Chen, J.M.4
Chandak, G.R.5
Masamune, A.6
Bence, M.7
Szmola, R.8
Oracz, G.9
Macek, M.10
Bhatia, E.11
Steigenberger, S.12
Lasher, D.13
Bühler, F.14
Delaporte, C.15
Tebbing, J.16
Ludwig, M.17
Pilsalc, C.18
Saum, K.19
Bugert, P.20
Masson, E.21
Paliwal, S.22
Bhaskar, S.23
Sobczynska-Tomaszewska, A.24
Bak, D.25
Balascak, I.26
Choudhuri, G.27
Nageshwar Reddy, D.28
Rao, G.V.29
Thomas, V.30
Kume, K.31
Nakano, E.32
Kalcuta, Y.33
Shimosegawa, T.34
Durko, L.35
Szabó, A.36
Schnúr, A.37
Hegyi, P.38
Rakonczay, Z.39
Pfützer, R.40
Schneider, A.41
Groneberg, D.A.42
Braun, M.43
Schmidt, H.44
Witt, U.45
Friess, H.46
Algül, H.47
Landt, O.48
Schuelke, M.49
Krüger, R.50
Wiedenmann, B.51
Schmidt, F.52
Zimmer, K.P.53
Kovacs, P.54
Stumvoll, M.55
Blüher, M.56
Müller, T.57
Janecke, A.58
Teich, N.59
Grützmann, R.60
Schulz, H.U.61
Mössner, J.62
Keim, V.63
Löhr, M.64
Férec, C.65
Sahin-Tóth, M.66
more..
-
46
-
-
79952310800
-
Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage
-
Lugea, A., Tischler, D., Nguyen, J., Gong, J., Gukovsky, I., French, S. W., Gorelick, F. S., and Pandol, S. J. (2011) Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage. Gastroenterology 140, 987-997
-
(2011)
Gastroenterology
, vol.140
, pp. 987-997
-
-
Lugea, A.1
Tischler, D.2
Nguyen, J.3
Gong, J.4
Gukovsky, I.5
French, S.W.6
Gorelick, F.S.7
Pandol, S.J.8
-
47
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
Lee, A. H., Chu, G. C., Iwakoshi, N. N., and Glimcher, L. H. (2005) XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J. 24, 4368-4380
-
(2005)
EMBO J.
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
48
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in Perk-/- mice reveals a role for translational control in secretory cell survival
-
Harding, H. P., Zeng, H., Zhang, Y., Jungries, R., Chung, P., Plesken, H., Sabatini, D. D., and Ron, D. (2001) Diabetes mellitus and exocrine pancreatic dysfunction in Perk-/- mice reveals a role for translational control in secretory cell survival. Mol. Cell 7, 1153-1163
-
(2001)
Mol. Cell
, vol.7
, pp. 1153-1163
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
Jungries, R.4
Chung, P.5
Plesken, H.6
Sabatini, D.D.7
Ron, D.8
-
49
-
-
84871272183
-
Activation of nuclear factor-κB in acinar cells increases the severity of pancreatitis in mice
-
Huang, H., Liu, Y., Daniluk, J., Gaiser, S., Chu, J., Wang, H., Li, Z. S., Logsdon, C. D., and Ji, B. (2013) Activation of nuclear factor-κB in acinar cells increases the severity of pancreatitis in mice. Gastroenterology 144, 202-210
-
(2013)
Gastroenterology
, vol.144
, pp. 202-210
-
-
Huang, H.1
Liu, Y.2
Daniluk, J.3
Gaiser, S.4
Chu, J.5
Wang, H.6
Li, Z.S.7
Logsdon, C.D.8
Ji, B.9
-
50
-
-
78751556358
-
Control of NF-κB and inflammation by the unfolded protein response
-
Kitamura, M. (2011) Control of NF-κB and inflammation by the unfolded protein response. Int. Rev. Immunol. 30, 4-15
-
(2011)
Int. Rev. Immunol.
, vol.30
, pp. 4-15
-
-
Kitamura, M.1
-
51
-
-
68949214606
-
Biphasic, bidirectional regulation of NF-κB by endoplasmic reticulum stress
-
Kitamura, M. (2009) Biphasic, bidirectional regulation of NF-κB by endoplasmic reticulum stress. Antioxid. Redox. Signal 11, 2353-2364
-
(2009)
Antioxid. Redox. Signal
, vol.11
, pp. 2353-2364
-
-
Kitamura, M.1
-
53
-
-
33947376068
-
Why does pancreatic overstimulation cause pancreatitis?
-
Saluja, A. K., Lerch, M. M., Phillips, P. A., and Dudeja, V. (2007) Why does pancreatic overstimulation cause pancreatitis? Annu. Rev. Physiol. 69, 249-269
-
(2007)
Annu. Rev. Physiol.
, vol.69
, pp. 249-269
-
-
Saluja, A.K.1
Lerch, M.M.2
Phillips, P.A.3
Dudeja, V.4
-
54
-
-
38549084647
-
The role of NF-κB activation in the pathogenesis of acute pancreatitis
-
Rakonczay, Z., Jr., Hegyi, P., Takács, T., McCarroll, J., and Saluja, A. K. (2008) The role of NF-κB activation in the pathogenesis of acute pancreatitis. Gut. 57, 259-267
-
(2008)
Gut.
, vol.57
, pp. 259-267
-
-
Rakonczay, Z.1
Hegyi, P.2
Takács, T.3
McCarroll, J.4
Saluja, A.K.5
-
55
-
-
79251534395
-
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes
-
Jia, W., Pua, H. H., Li, Q. J., and He, Y. W. (2011) Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. J. Immunol. 186, 1564-1574
-
(2011)
J. Immunol.
, vol.186
, pp. 1564-1574
-
-
Jia, W.1
Pua, H.H.2
Li, Q.J.3
He, Y.W.4
-
56
-
-
84872192695
-
An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases
-
Bhandary, B., Marahatta, A., Kim, H. R., and Chae, H. J. (2012) An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases. Int. J. Mol. Sci. 14, 434-456
-
(2012)
Int. J. Mol. Sci.
, vol.14
, pp. 434-456
-
-
Bhandary, B.1
Marahatta, A.2
Kim, H.R.3
Chae, H.J.4
-
57
-
-
29244462498
-
Coordination of ER and oxidative stress signaling: The PERI/Nrf2 signaling pathway
-
Cullinan, S. B., and Diehl, J. A. (2006) Coordination of ER and oxidative stress signaling: the PERI/Nrf2 signaling pathway. Int. J. Biochem. Cell Biol. 38, 317-332
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, pp. 317-332
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
58
-
-
33947274572
-
Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function
-
Tsang, K. Y., Chan, D., Cheslett, D., Chan, W. C, So, C. L., Melhado, I. G., Chan, T. W., Kwan, K. M., Hunziker, E. B., Yamada, Y., Bateman, J. F., Cheung, K. M., and Cheah, K. S. (2007) Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function. PLoS Biol. 5, e44
-
(2007)
PLoS Biol.
, vol.5
, pp. e44
-
-
Tsang, K.Y.1
Chan, D.2
Cheslett, D.3
Chan, W.C.4
So, C.L.5
Melhado, I.G.6
Chan, T.W.7
Kwan, K.M.8
Hunziker, E.B.9
Yamada, Y.10
Bateman, J.F.11
Cheung, K.M.12
Cheah, K.S.13
-
59
-
-
84897957330
-
Exonic variants affecting pre-mRNA splicing add to genetic burden in chronic pancreatitis
-
Beer, S., and Sahin-Tóth, M. (2014) Exonic variants affecting pre-mRNA splicing add to genetic burden in chronic pancreatitis. Gut 63, 860-861
-
(2014)
Gut
, vol.63
, pp. 860-861
-
-
Beer, S.1
Sahin-Tóth, M.2
-
60
-
-
84874659320
-
CFTR, SPINK1, CTRC, and PRSS1 variants in chronic pancreatitis: Is the role of mutated CFTR overestimated?
-
Rosendahl, J., Landt, O., Bernadova, J., Kovacs, P., Teich, N., Bödeker, H., Keim, V., Ruffert, C., Mössner, J., Kage, A., Stumvoll, M., Groneberg, D., Krüger, R., Luck, W., Treiber, M., Becker, M., and Witt, H. (2013) CFTR, SPINK1, CTRC, and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated? Gut. 62, 582-592
-
(2013)
Gut.
, vol.62
, pp. 582-592
-
-
Rosendahl, J.1
Landt, O.2
Bernadova, J.3
Kovacs, P.4
Teich, N.5
Bödeker, H.6
Keim, V.7
Ruffert, C.8
Mössner, J.9
Kage, A.10
Stumvoll, M.11
Groneberg, D.12
Krüger, R.13
Luck, W.14
Treiber, M.15
Becker, M.16
Witt, H.17
-
61
-
-
70350225542
-
Chronic pancreatitis: Genetics and pathogenesis
-
Chen, J. M., and Ferec, C. (2009) Chronic pancreatitis: genetics and pathogenesis. Annu. Rev. Genomics Hum. Genet. 10, 63-87
-
(2009)
Annu. Rev. Genomics Hum. Genet.
, vol.10
, pp. 63-87
-
-
Chen, J.M.1
Ferec, C.2
-
62
-
-
77951920963
-
Genetic aspects of pancreatitis
-
Whitcomb, D. C. (2010) Genetic aspects of pancreatitis. Annu. Rev. Med. 61,413-424
-
(2010)
Annu. Rev. Med.
, vol.61
, pp. 413-424
-
-
Whitcomb, D.C.1
-
63
-
-
33646028182
-
Biochemical models of hereditary pancreatitis
-
Sahin-Tóth, M. (2006) Biochemical models of hereditary pancreatitis. Endocrinol. Metab. Clin. North Am. 35, 303-312
-
(2006)
Endocrinol. Metab. Clin. North Am.
, vol.35
, pp. 303-312
-
-
Sahin-Tóth, M.1
-
65
-
-
33747773624
-
Association of cathepsin B gene polymorphisms with tropical calcific pancreatitis
-
Mahurkar, S., Idris, M. M., Reddy, D. N., Bhaskar, S., Rao, G. V., Thomas, V., Singh, L., and Chandak, G. R. (2006) Association of cathepsin B gene polymorphisms with tropical calcific pancreatitis. Gut. 55, 1270-1275
-
(2006)
Gut.
, vol.55
, pp. 1270-1275
-
-
Mahurkar, S.1
Idris, M.M.2
Reddy, D.N.3
Bhaskar, S.4
Rao, G.V.5
Thomas, V.6
Singh, L.7
Chandak, G.R.8
-
66
-
-
84885676141
-
Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants
-
Paliwal, S., Bhaskar, S., Mani, K. R., Reddy, D. N., Rao, G. V., Singh, S. P., Thomas, V., and Chandak, G. R. (2013) Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants. Gut 62, 1602-1606
-
(2013)
Gut
, vol.62
, pp. 1602-1606
-
-
Paliwal, S.1
Bhaskar, S.2
Mani, K.R.3
Reddy, D.N.4
Rao, G.V.5
Singh, S.P.6
Thomas, V.7
Chandak, G.R.8
-
67
-
-
80155186900
-
Roles of serine protease inhibitor Kazal type 1 (SPINK1) in pancreatic diseases
-
Ohmuraya, M., and Yam amura, K. (2011) Roles of serine protease inhibitor Kazal type 1 (SPINK1) in pancreatic diseases. Exp. Anim. 60, 433-444
-
(2011)
Exp. Anim.
, vol.60
, pp. 433-444
-
-
Ohmuraya, M.1
Yamamura, K.2
-
68
-
-
84866345751
-
Role of intrapancreatic SPINK1/Spink3 expression in the development of pancreatitis
-
Ohmuraya, M., Sugano, A., Hirota, M., Takaoka, Y., and Yam amura, K. (2012) Role of intrapancreatic SPINK1/Spink3 expression in the development of pancreatitis. Front Physiol. 3,126
-
(2012)
Front Physiol.
, vol.3
, pp. 126
-
-
Ohmuraya, M.1
Sugano, A.2
Hirota, M.3
Takaoka, Y.4
Yamamura, K.5
-
69
-
-
33747010658
-
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis
-
Teich, N., Rosendahl, J., Tóth, M., Mössner, J., and Sahin-Tóth, M. (2006) Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis. Hum. Mutat. 27, 721-730
-
(2006)
Hum. Mutat.
, vol.27
, pp. 721-730
-
-
Teich, N.1
Rosendahl, J.2
Tóth, M.3
Mössner, J.4
Sahin-Tóth, M.5
-
70
-
-
33845664588
-
A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen
-
Archer, H., Jura, N., Keller, J., Jacobson, M., and Bar-Sagi, D. (2006) A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen. Gastroenterology 131, 1844-1855
-
(2006)
Gastroenterology
, vol.131
, pp. 1844-1855
-
-
Archer, H.1
Jura, N.2
Keller, J.3
Jacobson, M.4
Bar-Sagi, D.5
|