Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network

Cell Reports

Volumn 8, Issue 5, 2014, Pages 1328-1338

  Fang, Jing ^a   Barker, Brenden ^a   Bolanos, Lyndsey ^a   Liu, Xiaona ^a   Jerez, Andres ^b   Makishima, Hideki ^b   Christie, Susanne ^a   Chen, Xiaoting ^a,c   Rao, Dinesh S ^d   Grimes, H Leighton ^a   Komurov, Kakajan ^a   Weirauch, Matthew T ^a   Cancelas, Jose A ^a,e   Maciejewski, Jaroslaw P ^b   Starczynowski, Daniel T ^a,e  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

^c University of Cincinnati   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; DEOXYRIBONUCLEASE I; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MICRORNA; MICRORNA 146A; PROTEIN P62; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; MIRN146 MICRORNA, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CD34 SELECTION; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL KINETICS; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME 5Q; CHROMOSOME DELETION; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REGULATORY NETWORK; GENE SEQUENCE; HAPLOIDY; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MYELODYSPLASTIC SYNDROME; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SQSTM1 GENE; STEM CELL; STOP CODON; TUMOR SUPPRESSOR GENE; ACUTE MYELOBLASTIC LEUKEMIA; ANIMAL; CASE CONTROL STUDY; CELL CULTURE; CELL CYCLE; CHROMOSOME 5; GENETICS; METABOLISM; MOUSE; MYELOID PROGENITOR CELL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; CASE-CONTROL STUDIES; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 5; GENE REGULATORY NETWORKS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MICRORNAS; MYELODYSPLASTIC SYNDROMES; MYELOID PROGENITOR CELLS; NF-KAPPA B; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84922561074     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.07.062     Document Type: Article

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