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Volumn 78, Issue 12, 2015, Pages 848-859

Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated with Anxiety-like Behavior in Mice

Author keywords

Anxiety; Behavior; Crybb1; Epigenetics; Gomafu; Noncoding RNA

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BETA CRYSTALLIN; BMI1 PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CRYSTALLIN; LONG UNTRANSLATED RNA; PENTRAXIN; PENTRAXIN 1; PROTEIN HOMER 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; CRYBB1 PROTEIN, MOUSE; HOMER SCAFFOLDING PROTEIN; MESSENGER RNA; POLYCOMB GROUP PROTEIN;

EID: 84946474781     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2015.02.004     Document Type: Article
Times cited : (108)

References (121)
  • 2
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs: Insights into functions
    • T.R. Mercer, M.E. Dinger, and J.S. Mattick Long non-coding RNAs: Insights into functions Nat Rev Genet 10 2009 155 159
    • (2009) Nat Rev Genet , vol.10 , pp. 155-159
    • Mercer, T.R.1    Dinger, M.E.2    Mattick, J.S.3
  • 4
    • 77952212771 scopus 로고    scopus 로고
    • RNA traffic control of chromatin complexes
    • M.J. Koziol, and J.L. Rinn RNA traffic control of chromatin complexes Curr Opin Genet Dev 20 2010 142 148
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 142-148
    • Koziol, M.J.1    Rinn, J.L.2
  • 5
    • 84875183056 scopus 로고    scopus 로고
    • Structure and function of long noncoding RNAs in epigenetic regulation
    • T.R. Mercer, and J.S. Mattick Structure and function of long noncoding RNAs in epigenetic regulation Nat Struct Mol Biol 20 2013 300 307
    • (2013) Nat Struct Mol Biol , vol.20 , pp. 300-307
    • Mercer, T.R.1    Mattick, J.S.2
  • 6
    • 21044431735 scopus 로고    scopus 로고
    • Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution
    • J. Cheng, P. Kapranov, J. Drenkow, S. Dike, S. Brubaker, S. Patel, and et al. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution Science 308 2005 1149 1154
    • (2005) Science , vol.308 , pp. 1149-1154
    • Cheng, J.1    Kapranov, P.2    Drenkow, J.3    Dike, S.4    Brubaker, S.5    Patel, S.6
  • 9
    • 80052978224 scopus 로고    scopus 로고
    • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
    • M.N. Cabili, C. Trapnell, L. Goff, M. Koziol, B. Tazon-Vega, A. Regev, and J.L. Rinn Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses Genes Dev 25 2011 1915 1927
    • (2011) Genes Dev , vol.25 , pp. 1915-1927
    • Cabili, M.N.1    Trapnell, C.2    Goff, L.3    Koziol, M.4    Tazon-Vega, B.5    Regev, A.6    Rinn, J.L.7
  • 11
    • 84860742355 scopus 로고    scopus 로고
    • NONCODE v3.0: Integrative annotation of long noncoding RNAs
    • D. Bu, K. Yu, S. Sun, C. Xie, G. Skogerbo, R. Miao, and et al. NONCODE v3.0: Integrative annotation of long noncoding RNAs Nucleic Acids Res 40 2012 D210 D215
    • (2012) Nucleic Acids Res , vol.40 , pp. D210-D215
    • Bu, D.1    Yu, K.2    Sun, S.3    Xie, C.4    Skogerbo, G.5    Miao, R.6
  • 12
    • 1842584883 scopus 로고    scopus 로고
    • RNA regulation: A new genetics?
    • J.S. Mattick RNA regulation: A new genetics? Nat Rev Genet 5 2004 316 323
    • (2004) Nat Rev Genet , vol.5 , pp. 316-323
    • Mattick, J.S.1
  • 13
    • 62249133709 scopus 로고    scopus 로고
    • Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
    • M. Guttman, I. Amit, M. Garber, C. French, M.F. Lin, D. Feldser, and et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals Nature 458 2009 223 227
    • (2009) Nature , vol.458 , pp. 223-227
    • Guttman, M.1    Amit, I.2    Garber, M.3    French, C.4    Lin, M.F.5    Feldser, D.6
  • 14
    • 65649092633 scopus 로고    scopus 로고
    • The genetic signatures of noncoding RNAs
    • J.S. Mattick The genetic signatures of noncoding RNAs PLoS Genet 5 2009 e1000459
    • (2009) PLoS Genet , vol.5 , pp. e1000459
    • Mattick, J.S.1
  • 17
    • 77954399763 scopus 로고    scopus 로고
    • Long noncoding RNA genes: Conservation of sequence and brain expression among diverse amniotes
    • R.A. Chodroff, L. Goodstadt, T.M. Sirey, P.L. Oliver, K.E. Davies, E.D. Green, and et al. Long noncoding RNA genes: Conservation of sequence and brain expression among diverse amniotes Genome Biol 11 2010 R72
    • (2010) Genome Biol , vol.11 , pp. R72
    • Chodroff, R.A.1    Goodstadt, L.2    Sirey, T.M.3    Oliver, P.L.4    Davies, K.E.5    Green, E.D.6
  • 18
    • 80052536392 scopus 로고    scopus 로고
    • RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders
    • M. Lin, E. Pedrosa, A. Shah, A. Hrabovsky, S. Maqbool, D. Zheng, and H.M. Lachman RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders PLoS One 6 2011 e23356
    • (2011) PLoS One , vol.6 , pp. e23356
    • Lin, M.1    Pedrosa, E.2    Shah, A.3    Hrabovsky, A.4    Maqbool, S.5    Zheng, D.6    Lachman, H.M.7
  • 19
    • 84890415138 scopus 로고    scopus 로고
    • Long non-coding RNA identification over mouse brain development by integrative modeling of chromatin and genomic features
    • J. Lv, H. Liu, Z. Huang, J. Su, H. He, Y. Xiu, and et al. Long non-coding RNA identification over mouse brain development by integrative modeling of chromatin and genomic features Nucleic Acids Res 41 2013 10044 10061
    • (2013) Nucleic Acids Res , vol.41 , pp. 10044-10061
    • Lv, J.1    Liu, H.2    Huang, Z.3    Su, J.4    He, H.5    Xiu, Y.6
  • 20
    • 84900791270 scopus 로고    scopus 로고
    • Developmental changes in the transcriptome of human cerebral cortex tissue: Long noncoding RNA transcripts
    • L. Lipovich, A.L. Tarca, J. Cai, H. Jia, H.T. Chugani, K.N. Sterner, and et al. Developmental changes in the transcriptome of human cerebral cortex tissue: Long noncoding RNA transcripts Cereb Cortex 24 2014 1451 1459
    • (2014) Cereb Cortex , vol.24 , pp. 1451-1459
    • Lipovich, L.1    Tarca, A.L.2    Cai, J.3    Jia, H.4    Chugani, H.T.5    Sterner, K.N.6
  • 21
    • 70149123708 scopus 로고    scopus 로고
    • Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain
    • J. Ponjavic, P.L. Oliver, G. Lunter, and C.P. Ponting Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain PLoS Genet 5 2009 e1000617
    • (2009) PLoS Genet , vol.5 , pp. e1000617
    • Ponjavic, J.1    Oliver, P.L.2    Lunter, G.3    Ponting, C.P.4
  • 22
    • 84856492490 scopus 로고    scopus 로고
    • Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
    • S.Y. Ng, R. Johnson, and L.W. Stanton Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors EMBO J 31 2012 522 533
    • (2012) EMBO J , vol.31 , pp. 522-533
    • Ng, S.Y.1    Johnson, R.2    Stanton, L.W.3
  • 23
    • 84881487023 scopus 로고    scopus 로고
    • The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis
    • S.Y. Ng, G.K. Bogu, B.S. Soh, and L.W. Stanton The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis Mol Cell 51 2013 349 359
    • (2013) Mol Cell , vol.51 , pp. 349-359
    • Ng, S.Y.1    Bogu, G.K.2    Soh, B.S.3    Stanton, L.W.4
  • 24
    • 77956882723 scopus 로고    scopus 로고
    • A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression
    • D. Bernard, K.V. Prasanth, V. Tripathi, S. Colasse, T. Nakamura, Z. Xuan, and et al. A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression EMBO J 29 2010 3082 3093
    • (2010) EMBO J , vol.29 , pp. 3082-3093
    • Bernard, D.1    Prasanth, K.V.2    Tripathi, V.3    Colasse, S.4    Nakamura, T.5    Xuan, Z.6
  • 25
    • 84880869776 scopus 로고    scopus 로고
    • Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model
    • P. Petazzi, J. Sandoval, K. Szczesna, O.C. Jorge, L. Roa, S. Sayols, and et al. Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model RNA Biol 10 2013 1197 1203
    • (2013) RNA Biol , vol.10 , pp. 1197-1203
    • Petazzi, P.1    Sandoval, J.2    Szczesna, K.3    Jorge, O.C.4    Roa, L.5    Sayols, S.6
  • 27
    • 84879385237 scopus 로고    scopus 로고
    • Aberrant expression of long noncoding RNAs in autistic brain
    • M.N. Ziats, and O.M. Rennert Aberrant expression of long noncoding RNAs in autistic brain J Mol Neurosci 49 2013 589 593
    • (2013) J Mol Neurosci , vol.49 , pp. 589-593
    • Ziats, M.N.1    Rennert, O.M.2
  • 29
    • 84897108067 scopus 로고    scopus 로고
    • The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing
    • G. Barry, J.A. Briggs, D.P. Vanichkina, E.M. Poth, N.J. Beveridge, V.S. Ratnu, and et al. The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing Mol Psychiatry 19 2014 486 494
    • (2014) Mol Psychiatry , vol.19 , pp. 486-494
    • Barry, G.1    Briggs, J.A.2    Vanichkina, D.P.3    Poth, E.M.4    Beveridge, N.J.5    Ratnu, V.S.6
  • 30
    • 84891870087 scopus 로고    scopus 로고
    • Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome
    • C. Pastori, V.J. Peschansky, D. Barbouth, A. Mehta, J.P. Silva, and C. Wahlestedt Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome Hum Genet 133 2014 59 67
    • (2014) Hum Genet , vol.133 , pp. 59-67
    • Pastori, C.1    Peschansky, V.J.2    Barbouth, D.3    Mehta, A.4    Silva, J.P.5    Wahlestedt, C.6
  • 31
    • 78651305638 scopus 로고    scopus 로고
    • Mining Affymetrix microarray data for long non-coding RNAs: Altered expression in the nucleus accumbens of heroin abusers
    • S.K. Michelhaugh, L. Lipovich, J. Blythe, H. Jia, G. Kapatos, and M.J. Bannon Mining Affymetrix microarray data for long non-coding RNAs: Altered expression in the nucleus accumbens of heroin abusers J Neurochem 116 2011 459 466
    • (2011) J Neurochem , vol.116 , pp. 459-466
    • Michelhaugh, S.K.1    Lipovich, L.2    Blythe, J.3    Jia, H.4    Kapatos, G.5    Bannon, M.J.6
  • 32
    • 84868644224 scopus 로고    scopus 로고
    • Transcriptome analysis of long non-coding RNAs of the nucleus accumbens in cocaine-conditioned mice
    • Q. Bu, Z. Hu, F. Chen, R. Zhu, Y. Deng, X. Shao, and et al. Transcriptome analysis of long non-coding RNAs of the nucleus accumbens in cocaine-conditioned mice J Neurochem 123 2012 790 799
    • (2012) J Neurochem , vol.123 , pp. 790-799
    • Bu, Q.1    Hu, Z.2    Chen, F.3    Zhu, R.4    Deng, Y.5    Shao, X.6
  • 33
    • 85027917682 scopus 로고    scopus 로고
    • Increased expression of MARCKS in post-mortem brain of violent suicide completers is related to transcription of a long, noncoding, antisense RNA
    • G. Punzi, G. Ursini, J.H. Shin, J.E. Kleinman, T.M. Hyde, and D.R. Weinberger Increased expression of MARCKS in post-mortem brain of violent suicide completers is related to transcription of a long, noncoding, antisense RNA Mol Psychiatry 19 2014 1057 1059
    • (2014) Mol Psychiatry , vol.19 , pp. 1057-1059
    • Punzi, G.1    Ursini, G.2    Shin, J.H.3    Kleinman, J.E.4    Hyde, T.M.5    Weinberger, D.R.6
  • 34
    • 3943107461 scopus 로고    scopus 로고
    • Role of a neuronal small non-messenger RNA: Behavioural alterations in BC1 RNA-deleted mice
    • L. Lewejohann, B.V. Skryabin, N. Sachser, C. Prehn, P. Heiduschka, S. Thanos, and et al. Role of a neuronal small non-messenger RNA: Behavioural alterations in BC1 RNA-deleted mice Behav Brain Res 154 2004 273 289
    • (2004) Behav Brain Res , vol.154 , pp. 273-289
    • Lewejohann, L.1    Skryabin, B.V.2    Sachser, N.3    Prehn, C.4    Heiduschka, P.5    Thanos, S.6
  • 35
    • 34548084302 scopus 로고    scopus 로고
    • The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum
    • D. Centonze, S. Rossi, I. Napoli, V. Mercaldo, C. Lacoux, F. Ferrari, and et al. The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum J Neurosci 27 2007 8885 8892
    • (2007) J Neurosci , vol.27 , pp. 8885-8892
    • Centonze, D.1    Rossi, S.2    Napoli, I.3    Mercaldo, V.4    Lacoux, C.5    Ferrari, F.6
  • 36
    • 84869016176 scopus 로고    scopus 로고
    • Activity-dependent human brain coding/noncoding gene regulatory networks
    • L. Lipovich, F. Dachet, J. Cai, S. Bagla, K. Balan, H. Jia, and J.A. Loeb Activity-dependent human brain coding/noncoding gene regulatory networks Genetics 192 2012 1133 1148
    • (2012) Genetics , vol.192 , pp. 1133-1148
    • Lipovich, L.1    Dachet, F.2    Cai, J.3    Bagla, S.4    Balan, K.5    Jia, H.6    Loeb, J.A.7
  • 37
    • 77952367798 scopus 로고    scopus 로고
    • Widespread transcription at neuronal activity-regulated enhancers
    • T.K. Kim, M. Hemberg, J.M. Gray, A.M. Costa, D.M. Bear, J. Wu, and et al. Widespread transcription at neuronal activity-regulated enhancers Nature 465 2010 182 187
    • (2010) Nature , vol.465 , pp. 182-187
    • Kim, T.K.1    Hemberg, M.2    Gray, J.M.3    Costa, A.M.4    Bear, D.M.5    Wu, J.6
  • 38
    • 52949129059 scopus 로고    scopus 로고
    • Animal models of anxiety: Do i need multiple tests?
    • A. Ramos Animal models of anxiety: Do I need multiple tests? Trends Pharmacol Sci 29 2008 493 498
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 493-498
    • Ramos, A.1
  • 39
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • C. Trapnell, L. Pachter, and S.L. Salzberg TopHat: Discovering splice junctions with RNA-Seq Bioinformatics 25 2009 1105 1111
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 40
    • 84859885816 scopus 로고    scopus 로고
    • Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
    • C. Trapnell, A. Roberts, L. Goff, G. Pertea, D. Kim, D.R. Kelley, and et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks Nat Protoc 7 2012 562 578
    • (2012) Nat Protoc , vol.7 , pp. 562-578
    • Trapnell, C.1    Roberts, A.2    Goff, L.3    Pertea, G.4    Kim, D.5    Kelley, D.R.6
  • 41
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • C. Trapnell, B.A. Williams, G. Pertea, A. Mortazavi, G. Kwan, M.J. van Baren, and et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation Nat Biotechnol 28 2010 511 515
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5    Van Baren, M.J.6
  • 43
    • 60149099385 scopus 로고    scopus 로고
    • Evolution and functions of long noncoding RNAs
    • C.P. Ponting, P.L. Oliver, and W. Reik Evolution and functions of long noncoding RNAs Cell 136 2009 629 641
    • (2009) Cell , vol.136 , pp. 629-641
    • Ponting, C.P.1    Oliver, P.L.2    Reik, W.3
  • 46
    • 84908179005 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase regulates activity-dependent BDNF expression in post-mitotic cortical neurons
    • V.S. Ratnu, W. Wei, and T.W. Bredy Activation-induced cytidine deaminase regulates activity-dependent BDNF expression in post-mitotic cortical neurons Eur J Neurosci 40 2014 3032 3039
    • (2014) Eur J Neurosci , vol.40 , pp. 3032-3039
    • Ratnu, V.S.1    Wei, W.2    Bredy, T.W.3
  • 47
    • 34247224239 scopus 로고    scopus 로고
    • Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear
    • T.W. Bredy, H. Wu, C. Crego, J. Zellhoefer, Y.E. Sun, and M. Barad Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear Learn Mem 14 2007 268 276
    • (2007) Learn Mem , vol.14 , pp. 268-276
    • Bredy, T.W.1    Wu, H.2    Crego, C.3    Zellhoefer, J.4    Sun, Y.E.5    Barad, M.6
  • 48
    • 84868641005 scopus 로고    scopus 로고
    • Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter
    • Y. Furukawa-Hibi, J. Yun, T. Nagai, and K. Yamada Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter J Neurochem 123 2012 866 875
    • (2012) J Neurochem , vol.123 , pp. 866-875
    • Furukawa-Hibi, Y.1    Yun, J.2    Nagai, T.3    Yamada, K.4
  • 49
    • 77956308661 scopus 로고    scopus 로고
    • Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice: Possible involvement of a brain-specific transcription factor Npas4
    • J. Yun, H. Koike, D. Ibi, E. Toth, H. Mizoguchi, A. Nitta, and et al. Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice: Possible involvement of a brain-specific transcription factor Npas4 J Neurochem 114 2010 1840 1851
    • (2010) J Neurochem , vol.114 , pp. 1840-1851
    • Yun, J.1    Koike, H.2    Ibi, D.3    Toth, E.4    Mizoguchi, H.5    Nitta, A.6
  • 50
    • 84883148404 scopus 로고    scopus 로고
    • Activity-dependent NPAS4 expression and the regulation of gene programs underlying plasticity in the central nervous system
    • J.F. Maya-Vetencourt Activity-dependent NPAS4 expression and the regulation of gene programs underlying plasticity in the central nervous system Neural Plast 2013 2013 683909
    • (2013) Neural Plast , vol.2013 , pp. 683909
    • Maya-Vetencourt, J.F.1
  • 51
    • 80051922481 scopus 로고    scopus 로고
    • The neuronal PAS domain protein 4 (Npas4) is required for new and reactivated fear memories
    • J.E. Ploski, M.S. Monsey, T. Nguyen, R.J. DiLeone, and G.E. Schafe The neuronal PAS domain protein 4 (Npas4) is required for new and reactivated fear memories PloS One 6 2011 e23760
    • (2011) PloS One , vol.6 , pp. e23760
    • Ploski, J.E.1    Monsey, M.S.2    Nguyen, T.3    DiLeone, R.J.4    Schafe, G.E.5
  • 52
    • 80053969185 scopus 로고    scopus 로고
    • Incubation of conditioning-specific reflex modification: Implications for post traumatic stress disorder
    • B.G. Schreurs, C.A. Smith-Bell, and L.B. Burhans Incubation of conditioning-specific reflex modification: Implications for post traumatic stress disorder J Psychiatr Res 45 2011 1535 1541
    • (2011) J Psychiatr Res , vol.45 , pp. 1535-1541
    • Schreurs, B.G.1    Smith-Bell, C.A.2    Burhans, L.B.3
  • 53
    • 34247871449 scopus 로고    scopus 로고
    • A mouse model of posttraumatic stress disorder that distinguishes between conditioned and sensitised fear
    • A. Siegmund, and C.T. Wotjak A mouse model of posttraumatic stress disorder that distinguishes between conditioned and sensitised fear J Psychiatr Res 41 2007 848 860
    • (2007) J Psychiatr Res , vol.41 , pp. 848-860
    • Siegmund, A.1    Wotjak, C.T.2
  • 54
    • 10044272343 scopus 로고    scopus 로고
    • Nonassociative learning processes determine expression and extinction of conditioned fear in mice
    • K. Kamprath, and C.T. Wotjak Nonassociative learning processes determine expression and extinction of conditioned fear in mice Learn Mem 11 2004 770 786
    • (2004) Learn Mem , vol.11 , pp. 770-786
    • Kamprath, K.1    Wotjak, C.T.2
  • 56
    • 77950965423 scopus 로고    scopus 로고
    • Neuronal pentraxins mediate silent synapse conversion in the developing visual system
    • S.M. Koch, and E.M. Ullian Neuronal pentraxins mediate silent synapse conversion in the developing visual system J Neurosci 30 2010 5404 5414
    • (2010) J Neurosci , vol.30 , pp. 5404-5414
    • Koch, S.M.1    Ullian, E.M.2
  • 58
    • 70350525706 scopus 로고    scopus 로고
    • Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder
    • M.R. Milad, R.K. Pitman, C.B. Ellis, A.L. Gold, L.M. Shin, N.B. Lasko, and et al. Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder Biol Psychiatry 66 2009 1075 1082
    • (2009) Biol Psychiatry , vol.66 , pp. 1075-1082
    • Milad, M.R.1    Pitman, R.K.2    Ellis, C.B.3    Gold, A.L.4    Shin, L.M.5    Lasko, N.B.6
  • 59
    • 33748678305 scopus 로고    scopus 로고
    • Postreactivation glucocorticoids impair recall of established fear memory
    • W.H. Cai, J. Blundell, J. Han, R.W. Greene, and C.M. Powell Postreactivation glucocorticoids impair recall of established fear memory J Neurosci 26 2006 9560 9566
    • (2006) J Neurosci , vol.26 , pp. 9560-9566
    • Cai, W.H.1    Blundell, J.2    Han, J.3    Greene, R.W.4    Powell, C.M.5
  • 63
    • 77956927823 scopus 로고    scopus 로고
    • The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
    • V. Tripathi, J.D. Ellis, Z. Shen, D.Y. Song, Q. Pan, A.T. Watt, and et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation Mol Cell 39 2010 925 938
    • (2010) Mol Cell , vol.39 , pp. 925-938
    • Tripathi, V.1    Ellis, J.D.2    Shen, Z.3    Song, D.Y.4    Pan, Q.5    Watt, A.T.6
  • 64
    • 84876003231 scopus 로고    scopus 로고
    • Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB
    • V. Tripathi, Z. Shen, A. Chakraborty, S. Giri, S.M. Freier, X. Wu, and et al. Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB PLoS Genet 9 2013 e1003368
    • (2013) PLoS Genet , vol.9 , pp. e1003368
    • Tripathi, V.1    Shen, Z.2    Chakraborty, A.3    Giri, S.4    Freier, S.M.5    Wu, X.6
  • 65
    • 84864315112 scopus 로고    scopus 로고
    • The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult
    • B. Zhang, G. Arun, Y.S. Mao, Z. Lazar, G. Hung, G. Bhattacharjee, and et al. The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult Cell Rep 2 2012 111 123
    • (2012) Cell Rep , vol.2 , pp. 111-123
    • Zhang, B.1    Arun, G.2    Mao, Y.S.3    Lazar, Z.4    Hung, G.5    Bhattacharjee, G.6
  • 66
    • 77955199612 scopus 로고    scopus 로고
    • Heat shock proteins: Cellular and molecular mechanisms in the central nervous system
    • R.A. Stetler, Y. Gan, W. Zhang, A.K. Liou, Y. Gao, G. Cao, and J. Chen Heat shock proteins: Cellular and molecular mechanisms in the central nervous system Prog Neurobiol 92 2010 184 211
    • (2010) Prog Neurobiol , vol.92 , pp. 184-211
    • Stetler, R.A.1    Gan, Y.2    Zhang, W.3    Liou, A.K.4    Gao, Y.5    Cao, G.6    Chen, J.7
  • 67
    • 64149121709 scopus 로고    scopus 로고
    • Induction of heat shock proteins for protection against oxidative stress
    • B. Kalmar, and L. Greensmith Induction of heat shock proteins for protection against oxidative stress Adv Drug Deliv Rev 61 2009 310 318
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 310-318
    • Kalmar, B.1    Greensmith, L.2
  • 68
    • 84876513077 scopus 로고    scopus 로고
    • The human crystallin gene families
    • G. Wistow The human crystallin gene families Human Genomics 6 2012 26
    • (2012) Human Genomics , vol.6 , pp. 26
    • Wistow, G.1
  • 70
    • 84897489303 scopus 로고    scopus 로고
    • Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers
    • L.Y. Chang, J. Lowe, A. Ardiles, J. Lim, A.C. Grey, K. Robertson, and et al. Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers Alzheimers Dement 10 2014 251 261
    • (2014) Alzheimers Dement , vol.10 , pp. 251-261
    • Chang, L.Y.1    Lowe, J.2    Ardiles, A.3    Lim, J.4    Grey, A.C.5    Robertson, K.6
  • 71
    • 84899425563 scopus 로고    scopus 로고
    • The N-terminal extension of betaB1-crystallin chaperones beta-crystallin folding and cooperates with alphaA-crystallin
    • X.Y. Leng, S. Wang, N.Q. Cao, L.B. Qi, and Y.B. Yan The N-terminal extension of betaB1-crystallin chaperones beta-crystallin folding and cooperates with alphaA-crystallin Biochemistry 53 2014 2464 2473
    • (2014) Biochemistry , vol.53 , pp. 2464-2473
    • Leng, X.Y.1    Wang, S.2    Cao, N.Q.3    Qi, L.B.4    Yan, Y.B.5
  • 72
  • 73
    • 0029874880 scopus 로고    scopus 로고
    • A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22)
    • M. Gill, H. Vallada, D. Collier, P. Sham, P. Holmans, R. Murray, and et al. A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22) Am J Med Genet 67 1996 40 45
    • (1996) Am J Med Genet , vol.67 , pp. 40-45
    • Gill, M.1    Vallada, H.2    Collier, D.3    Sham, P.4    Holmans, P.5    Murray, R.6
  • 75
    • 0028082293 scopus 로고
    • Sequential strategy to identify a susceptibility gene for schizophrenia: Report of potential linkage on chromosome 22q12-q13.1
    • A.E. Pulver, M. Karayiorgou, P.S. Wolyniec, V.K. Lasseter, L. Kasch, G. Nestadt, and et al. Sequential strategy to identify a susceptibility gene for schizophrenia: Report of potential linkage on chromosome 22q12-q13.1 Am J Med Genet 54 1994 36 43
    • (1994) Am J Med Genet , vol.54 , pp. 36-43
    • Pulver, A.E.1    Karayiorgou, M.2    Wolyniec, P.S.3    Lasseter, V.K.4    Kasch, L.5    Nestadt, G.6
  • 76
    • 67650921949 scopus 로고    scopus 로고
    • Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
    • A.M. Khalil, M. Guttman, M. Huarte, M. Garber, A. Raj, D. Rivea Morales, and et al. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression Proc Natl Acad Sci U S A 106 2009 11667 11672
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11667-11672
    • Khalil, A.M.1    Guttman, M.2    Huarte, M.3    Garber, M.4    Raj, A.5    Rivea Morales, D.6
  • 77
    • 84884782873 scopus 로고    scopus 로고
    • Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2
    • O. Marin-Bejar, F.P. Marchese, A. Athie, Y. Sanchez, J. Gonzalez, V. Segura, and et al. Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2 Genome Biol 14 2013 R104
    • (2013) Genome Biol , vol.14 , pp. R104
    • Marin-Bejar, O.1    Marchese, F.P.2    Athie, A.3    Sanchez, Y.4    Gonzalez, J.5    Segura, V.6
  • 78
    • 34250729138 scopus 로고    scopus 로고
    • Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
    • J.L. Rinn, M. Kertesz, J.K. Wang, S.L. Squazzo, X. Xu, S.A. Brugmann, and et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs Cell 129 2007 1311 1323
    • (2007) Cell , vol.129 , pp. 1311-1323
    • Rinn, J.L.1    Kertesz, M.2    Wang, J.K.3    Squazzo, S.L.4    Xu, X.5    Brugmann, S.A.6
  • 79
    • 79955468280 scopus 로고    scopus 로고
    • Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
    • Y. Kotake, T. Nakagawa, K. Kitagawa, S. Suzuki, N. Liu, M. Kitagawa, and et al. Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene Oncogene 30 2011 1956 1962
    • (2011) Oncogene , vol.30 , pp. 1956-1962
    • Kotake, Y.1    Nakagawa, T.2    Kitagawa, K.3    Suzuki, S.4    Liu, N.5    Kitagawa, M.6
  • 80
    • 77953096072 scopus 로고    scopus 로고
    • Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
    • K.L. Yap, S. Li, A.M. Munoz-Cabello, S. Raguz, L. Zeng, S. Mujtaba, and et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a Mol Cell 38 2010 662 674
    • (2010) Mol Cell , vol.38 , pp. 662-674
    • Yap, K.L.1    Li, S.2    Munoz-Cabello, A.M.3    Raguz, S.4    Zeng, L.5    Mujtaba, S.6
  • 81
    • 77954572735 scopus 로고    scopus 로고
    • Long noncoding RNA as modular scaffold of histone modification complexes
    • M.C. Tsai, O. Manor, Y. Wan, N. Mosammaparast, J.K. Wang, F. Lan, and et al. Long noncoding RNA as modular scaffold of histone modification complexes Science 329 2010 689 693
    • (2010) Science , vol.329 , pp. 689-693
    • Tsai, M.C.1    Manor, O.2    Wan, Y.3    Mosammaparast, N.4    Wang, J.K.5    Lan, F.6
  • 82
    • 77958475314 scopus 로고    scopus 로고
    • Identification and characterization of Bmi-1-responding element within the human p16 promoter
    • S. Meng, M. Luo, H. Sun, X. Yu, M. Shen, Q. Zhang, and et al. Identification and characterization of Bmi-1-responding element within the human p16 promoter J Biol Chem 285 2010 33219 33229
    • (2010) J Biol Chem , vol.285 , pp. 33219-33229
    • Meng, S.1    Luo, M.2    Sun, H.3    Yu, X.4    Shen, M.5    Zhang, Q.6
  • 83
    • 84864380003 scopus 로고    scopus 로고
    • Neural and cellular mechanisms of fear and extinction memory formation
    • C.A. Orsini, and S. Maren Neural and cellular mechanisms of fear and extinction memory formation Neurosci Biobehav Rev 36 2012 1773 1802
    • (2012) Neurosci Biobehav Rev , vol.36 , pp. 1773-1802
    • Orsini, C.A.1    Maren, S.2
  • 84
    • 37749011773 scopus 로고    scopus 로고
    • The human dimension: How the prefrontal cortex modulates the subcortical fear response
    • R.L. Berkowitz, J.D. Coplan, D.P. Reddy, and J.M. Gorman The human dimension: How the prefrontal cortex modulates the subcortical fear response Rev Neurosci 18 2007 191 207
    • (2007) Rev Neurosci , vol.18 , pp. 191-207
    • Berkowitz, R.L.1    Coplan, J.D.2    Reddy, D.P.3    Gorman, J.M.4
  • 85
    • 79551663314 scopus 로고    scopus 로고
    • Fear-conditioning mechanisms associated with trait vulnerability to anxiety in humans
    • I. Indovina, T.W. Robbins, A.O. Nunez-Elizalde, B.D. Dunn, and S.J. Bishop Fear-conditioning mechanisms associated with trait vulnerability to anxiety in humans Neuron 69 2011 563 571
    • (2011) Neuron , vol.69 , pp. 563-571
    • Indovina, I.1    Robbins, T.W.2    Nunez-Elizalde, A.O.3    Dunn, B.D.4    Bishop, S.J.5
  • 86
    • 84863284778 scopus 로고    scopus 로고
    • Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex
    • E.Y. Yuen, J. Wei, W. Liu, P. Zhong, X. Li, and Z. Yan Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex Neuron 73 2012 962 977
    • (2012) Neuron , vol.73 , pp. 962-977
    • Yuen, E.Y.1    Wei, J.2    Liu, W.3    Zhong, P.4    Li, X.5    Yan, Z.6
  • 87
    • 34250188967 scopus 로고    scopus 로고
    • Selection for contextual fear conditioning affects anxiety-like behaviors and gene expression
    • C.A. Ponder, C.L. Kliethermes, M.R. Drew, J. Muller, K. Das, V.B. Risbrough, and et al. Selection for contextual fear conditioning affects anxiety-like behaviors and gene expression Genes Brain Behav 6 2007 736 749
    • (2007) Genes Brain Behav , vol.6 , pp. 736-749
    • Ponder, C.A.1    Kliethermes, C.L.2    Drew, M.R.3    Muller, J.4    Das, K.5    Risbrough, V.B.6
  • 88
    • 79953311277 scopus 로고    scopus 로고
    • Prefrontal cortical network connections: Key site of vulnerability in stress and schizophrenia
    • A.F. Arnsten Prefrontal cortical network connections: Key site of vulnerability in stress and schizophrenia Int J Dev Neurosci 29 2011 215 223
    • (2011) Int J Dev Neurosci , vol.29 , pp. 215-223
    • Arnsten, A.F.1
  • 89
    • 49249103817 scopus 로고    scopus 로고
    • Molecular mechanisms of stress-induced prefrontal cortical impairment: Implications for mental illness
    • A.B. Hains, and A.F. Arnsten Molecular mechanisms of stress-induced prefrontal cortical impairment: Implications for mental illness Learn Mem 15 2008 551 564
    • (2008) Learn Mem , vol.15 , pp. 551-564
    • Hains, A.B.1    Arnsten, A.F.2
  • 91
    • 70350754524 scopus 로고    scopus 로고
    • The prevalence of comorbid anxiety disorders in outpatients with schizophrenia
    • M. Nebioglu, and A. Altindag The prevalence of comorbid anxiety disorders in outpatients with schizophrenia Int J Psychiatry Clin Pract 13 2009 312 317
    • (2009) Int J Psychiatry Clin Pract , vol.13 , pp. 312-317
    • Nebioglu, M.1    Altindag, A.2
  • 92
    • 34548433003 scopus 로고    scopus 로고
    • Anxiety symptoms in schizophrenia spectrum disorders: Associations with social function, positive and negative symptoms, hope and trauma history
    • P.H. Lysaker, and M.P. Salyers Anxiety symptoms in schizophrenia spectrum disorders: Associations with social function, positive and negative symptoms, hope and trauma history Acta Psychiatr Scand 116 2007 290 298
    • (2007) Acta Psychiatr Scand , vol.116 , pp. 290-298
    • Lysaker, P.H.1    Salyers, M.P.2
  • 93
    • 79959720275 scopus 로고    scopus 로고
    • How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association
    • A.M. Achim, M. Maziade, E. Raymond, D. Olivier, C. Merette, and M.A. Roy How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association Schizophr Bull 37 2011 811 821
    • (2011) Schizophr Bull , vol.37 , pp. 811-821
    • Achim, A.M.1    Maziade, M.2    Raymond, E.3    Olivier, D.4    Merette, C.5    Roy, M.A.6
  • 94
    • 84876796434 scopus 로고    scopus 로고
    • Anxiety disorder comorbidity in bipolar disorder, schizophrenia and schizoaffective disorder
    • S. Young, D. Pfaff, K.E. Lewandowski, C. Ravichandran, B.M. Cohen, and D. Ongur Anxiety disorder comorbidity in bipolar disorder, schizophrenia and schizoaffective disorder Psychopathology 46 2013 176 185
    • (2013) Psychopathology , vol.46 , pp. 176-185
    • Young, S.1    Pfaff, D.2    Lewandowski, K.E.3    Ravichandran, C.4    Cohen, B.M.5    Ongur, D.6
  • 97
    • 34548291568 scopus 로고    scopus 로고
    • The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons
    • M. Sone, T. Hayashi, H. Tarui, K. Agata, M. Takeichi, and S. Nakagawa The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons J Cell Sci 120 2007 2498 2506
    • (2007) J Cell Sci , vol.120 , pp. 2498-2506
    • Sone, M.1    Hayashi, T.2    Tarui, H.3    Agata, K.4    Takeichi, M.5    Nakagawa, S.6
  • 98
    • 33646574284 scopus 로고    scopus 로고
    • Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia
    • K. Aberg, P. Saetre, N. Jareborg, and E. Jazin Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia Proc Natl Acad Sci U S A 103 2006 7482 7487
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7482-7487
    • Aberg, K.1    Saetre, P.2    Jareborg, N.3    Jazin, E.4
  • 100
    • 33749480900 scopus 로고    scopus 로고
    • The human homolog of the QKI gene affected in the severe dysmyelination «quaking» mouse phenotype: Downregulated in multiple brain regions in schizophrenia
    • V. Haroutunian, P. Katsel, S. Dracheva, and K.L. Davis The human homolog of the QKI gene affected in the severe dysmyelination «quaking» mouse phenotype: Downregulated in multiple brain regions in schizophrenia Am J Psychiatry 163 2006 1834 1837
    • (2006) Am J Psychiatry , vol.163 , pp. 1834-1837
    • Haroutunian, V.1    Katsel, P.2    Dracheva, S.3    Davis, K.L.4
  • 102
    • 84858976475 scopus 로고    scopus 로고
    • Epigenetic features are significantly associated with alternative splicing
    • Y.P. Zhou, Y.L. Lu, and W.D. Tian Epigenetic features are significantly associated with alternative splicing BMC Genomics 13 2012 123
    • (2012) BMC Genomics , vol.13 , pp. 123
    • Zhou, Y.P.1    Lu, Y.L.2    Tian, W.D.3
  • 103
    • 84881024808 scopus 로고    scopus 로고
    • DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements
    • T.R. Mercer, S.L. Edwards, M.B. Clark, S.J. Neph, H. Wang, A.B. Stergachis, and et al. DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements Nat Genet 45 2013 852 859
    • (2013) Nat Genet , vol.45 , pp. 852-859
    • Mercer, T.R.1    Edwards, S.L.2    Clark, M.B.3    Neph, S.J.4    Wang, H.5    Stergachis, A.B.6
  • 104
    • 84880060145 scopus 로고    scopus 로고
    • Understanding the regulatory and transcriptional complexity of the genome through structure
    • T.R. Mercer, and J.S. Mattick Understanding the regulatory and transcriptional complexity of the genome through structure Genome Res 23 2013 1081 1088
    • (2013) Genome Res , vol.23 , pp. 1081-1088
    • Mercer, T.R.1    Mattick, J.S.2
  • 105
    • 84864553255 scopus 로고    scopus 로고
    • Pre-mRNA splicing: Role of epigenetics and implications in disease
    • D.H. Khan, S. Jahan, and J.R. Davie Pre-mRNA splicing: Role of epigenetics and implications in disease Adv Biol Regul 52 2012 377 388
    • (2012) Adv Biol Regul , vol.52 , pp. 377-388
    • Khan, D.H.1    Jahan, S.2    Davie, J.R.3
  • 106
    • 34249724360 scopus 로고    scopus 로고
    • Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease
    • M.F. Mehler, and J.S. Mattick Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease Physiol Rev 87 2007 799 823
    • (2007) Physiol Rev , vol.87 , pp. 799-823
    • Mehler, M.F.1    Mattick, J.S.2
  • 107
    • 0036239387 scopus 로고    scopus 로고
    • A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder
    • L.E. DeLisi, S.H. Shaw, T.J. Crow, G. Shields, A.B. Smith, V.W. Larach, and et al. A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder Am J Psychiatry 159 2002 803 812
    • (2002) Am J Psychiatry , vol.159 , pp. 803-812
    • DeLisi, L.E.1    Shaw, S.H.2    Crow, T.J.3    Shields, G.4    Smith, A.B.5    Larach, V.W.6
  • 108
    • 66049157839 scopus 로고    scopus 로고
    • Initiation codon mutation in betaB1-crystallin (CRYBB1) associated with autosomal recessive nuclear pulverulent cataract
    • E. Meyer, F. Rahman, J. Owens, S. Pasha, N.V. Morgan, R.C. Trembath, and et al. Initiation codon mutation in betaB1-crystallin (CRYBB1) associated with autosomal recessive nuclear pulverulent cataract Mol Vis 15 2009 1014 1019
    • (2009) Mol Vis , vol.15 , pp. 1014-1019
    • Meyer, E.1    Rahman, F.2    Owens, J.3    Pasha, S.4    Morgan, N.V.5    Trembath, R.C.6
  • 109
    • 84897109044 scopus 로고    scopus 로고
    • Molecular genetics of congenital nuclear cataract
    • H. Deng, and L. Yuan Molecular genetics of congenital nuclear cataract Eur J Med Genet 57 2014 113 122
    • (2014) Eur J Med Genet , vol.57 , pp. 113-122
    • Deng, H.1    Yuan, L.2
  • 110
    • 33947134834 scopus 로고    scopus 로고
    • The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
    • A.P. Bracken, D. Kleine-Kohlbrecher, N. Dietrich, D. Pasini, G. Gargiulo, C. Beekman, and et al. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells Genes Dev 21 2007 525 530
    • (2007) Genes Dev , vol.21 , pp. 525-530
    • Bracken, A.P.1    Kleine-Kohlbrecher, D.2    Dietrich, N.3    Pasini, D.4    Gargiulo, G.5    Beekman, C.6
  • 111
    • 84877836210 scopus 로고    scopus 로고
    • In vivo RNAi screen for BMI1 targets identifies TGF-beta/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis
    • G. Gargiulo, M. Cesaroni, M. Serresi, N. de Vries, D. Hulsman, S.W. Bruggeman, and et al. In vivo RNAi screen for BMI1 targets identifies TGF-beta/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis Cancer Cell 23 2013 660 676
    • (2013) Cancer Cell , vol.23 , pp. 660-676
    • Gargiulo, G.1    Cesaroni, M.2    Serresi, M.3    De Vries, N.4    Hulsman, D.5    Bruggeman, S.W.6
  • 112
    • 84860991298 scopus 로고    scopus 로고
    • Bmi1 confers resistance to oxidative stress on hematopoietic stem cells
    • S. Nakamura, M. Oshima, J. Yuan, A. Saraya, S. Miyagi, T. Konuma, and et al. Bmi1 confers resistance to oxidative stress on hematopoietic stem cells PloS One 7 2012 e36209
    • (2012) PloS One , vol.7 , pp. e36209
    • Nakamura, S.1    Oshima, M.2    Yuan, J.3    Saraya, A.4    Miyagi, S.5    Konuma, T.6
  • 113
    • 84881232015 scopus 로고    scopus 로고
    • Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation
    • M. Calao, E.O. Sekyere, H.J. Cui, B.B. Cheung, W.D. Thomas, J. Keating, and et al. Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation Oncogene 32 2013 3616 3626
    • (2013) Oncogene , vol.32 , pp. 3616-3626
    • Calao, M.1    Sekyere, E.O.2    Cui, H.J.3    Cheung, B.B.4    Thomas, W.D.5    Keating, J.6
  • 114
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • A.V. Molofsky, R. Pardal, T. Iwashita, I.K. Park, M.F. Clarke, and S.J. Morrison Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation Nature 425 2003 962 967
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 115
    • 22344449361 scopus 로고    scopus 로고
    • Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
    • A.V. Molofsky, S. He, M. Bydon, S.J. Morrison, and R. Pardal Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways Genes Dev 19 2005 1432 1437
    • (2005) Genes Dev , vol.19 , pp. 1432-1437
    • Molofsky, A.V.1    He, S.2    Bydon, M.3    Morrison, S.J.4    Pardal, R.5
  • 116
    • 34249907279 scopus 로고    scopus 로고
    • ShRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development
    • C.A. Fasano, J.T. Dimos, N.B. Ivanova, N. Lowry, I.R. Lemischka, and S. Temple shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development Cell Stem Cell 1 2007 87 99
    • (2007) Cell Stem Cell , vol.1 , pp. 87-99
    • Fasano, C.A.1    Dimos, J.T.2    Ivanova, N.B.3    Lowry, N.4    Lemischka, I.R.5    Temple, S.6
  • 117
    • 61849144426 scopus 로고    scopus 로고
    • Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain
    • C.A. Fasano, T.N. Phoenix, E. Kokovay, N. Lowry, Y. Elkabetz, J.T. Dimos, and et al. Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain Genes Dev 23 2009 561 574
    • (2009) Genes Dev , vol.23 , pp. 561-574
    • Fasano, C.A.1    Phoenix, T.N.2    Kokovay, E.3    Lowry, N.4    Elkabetz, Y.5    Dimos, J.T.6
  • 118
    • 63549087793 scopus 로고    scopus 로고
    • Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo
    • S. He, T. Iwashita, J. Buchstaller, A.V. Molofsky, D. Thomas, and S.J. Morrison Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo Dev Biol 328 2009 257 272
    • (2009) Dev Biol , vol.328 , pp. 257-272
    • He, S.1    Iwashita, T.2    Buchstaller, J.3    Molofsky, A.V.4    Thomas, D.5    Morrison, S.J.6
  • 119
    • 58849166901 scopus 로고    scopus 로고
    • The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity
    • W. Chatoo, M. Abdouh, J. David, M.P. Champagne, J. Ferreira, F. Rodier, and G. Bernier The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity J Neurosci 29 2009 529 542
    • (2009) J Neurosci , vol.29 , pp. 529-542
    • Chatoo, W.1    Abdouh, M.2    David, J.3    Champagne, M.P.4    Ferreira, J.5    Rodier, F.6    Bernier, G.7
  • 120
    • 84857567368 scopus 로고    scopus 로고
    • Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons
    • M. Abdouh, W. Chatoo, J. El Hajjar, J. David, J. Ferreira, and G. Bernier Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons PloS One 7 2012 e31870
    • (2012) PloS One , vol.7 , pp. e31870
    • Abdouh, M.1    Chatoo, W.2    El Hajjar, J.3    David, J.4    Ferreira, J.5    Bernier, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.