Taxifolin curbs NF-κB-mediated Wnt/β-catenin signaling via up-regulating Nrf2 pathway in experimental colon carcinogenesis

Biochimie

Volumn 119, Issue , 2015, Pages 103-112

  Manigandan, Krishnan ^a   Manimaran, Dharmar ^a   Jayaraj, Richard L ^b   Elangovan, Namasivayam ^a   Dhivya, Velumani ^c   Kaphle, Anubhav ^d  

^a PERIYAR UNIVERSITY   (India)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c BHARATHIAR UNIVERSITY   (India)

^d SIDDAGANGA INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Colon cancer; DMH; Docking; Nrf2; Taxifolin; Wnt catenin

Indexed keywords

BETA CATENIN; CARCINOEMBRYONIC ANTIGEN; CYCLIN D1; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; TAXIFOLIN; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; WNT PROTEIN; 1,2 DIMETHYLHYDRAZINE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CARCINOGEN; CTNNB1 PROTEIN, MOUSE; LIGAND; NFE2L2 PROTEIN, MOUSE; NONSTEROID ANTIINFLAMMATORY AGENT; QUERCETIN; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER INFILTRATION; COLON CANCER; COLON CARCINOGENESIS; COMPUTER MODEL; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; MAST CELL; MOLECULAR DOCKING; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; UPREGULATION; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; COLON; COLONIC NEOPLASMS; DRUG EFFECTS; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; RANDOMIZATION; WNT SIGNALING PATHWAY;

1,2-DIMETHYLHYDRAZINE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; BETA CATENIN; CARCINOGENS; COLON; COLONIC NEOPLASMS; HUMANS; INTESTINAL MUCOSA; LIGANDS; MALE; MAST CELLS; MICE; MOLECULAR DOCKING SIMULATION; NEOPLASM PROTEINS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; QUERCETIN; RANDOM ALLOCATION; WNT SIGNALING PATHWAY;

EID: 84946401916     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2015.10.014     Document Type: Article

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