Taxifolin ameliorates 1,2-dimethylhydrazine induced cell proliferation and redox avulsions in mice colon carcinogenesis

Biomedicine and Preventive Nutrition

Volumn 4, Issue 4, 2014, Pages 499-509

  Manigandan, Krishnan ^a   Jayaraj, Richard L ^a   Elangovan, Namasivayam ^a  

^a PERIYAR UNIVERSITY   (India)

Author keywords

ACF; Colon cancer; DMH; DNA damage; Oxidative stress; PCNA; Taxifolin

Indexed keywords

1,2 DIMETHYLHYDRAZINE; ALPHA TOCOPHEROL; ASCORBIC ACID; CATALASE; CYCLINE; FLUOROURACIL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALONALDEHYDE; MUCIN; MYELOPEROXIDASE; RETINOL; SUPEROXIDE DISMUTASE; TAXIFOLIN;

ABERRANT CRYPT FOCUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHEMOPROPHYLAXIS; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; DRUG EFFICACY; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS;

MUS;

EID: 84908461494     PISSN: 22105239     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bionut.2014.08.009     Document Type: Article

References (62)

1. Pierini R., Gee J.M., Belshaw N.J., Johnson I.T. Flavonoids and intestinal cancers. Br J Nutr 2008, 99:53-59.
2. Day D.W. The adenoma-carcinoma sequence. Scand J Gastroenterol Suppl 1984, 104:99-107.
3. Vrieling A., Kampman E. The role of body mass index, physical activity, and diet in colorectal cancer recurrence and survival: a review of the literature. Am J Clin Nutr 2010, 92:471-490.
4. Newell L.E., Heddle J.A. The potent colon carcinogen, 1,2-dimethylhydrazine induces mutations primarily in the colon. Mutat Res 2004, 564:1-7.
5. Rosenberg D.W., Liu Y. Induction of aberrant crypts in murine colon with varying sensitivity to colon carcinogenesis. Cancer Lett 1995, 92:209-214.
6. Choudhary G., Hansen H. Human health perspective on environmental exposure to hydrazines: a review. Chemosphere 1998, 37:801-843.
7. Khan R., Sultana S. Farnesol attenuates 1,2-dimethylhydrazine induced oxidative stress, inflammation and apoptotic responses in the colon of Wistar rats. Chem Biol Interact 2011, 192:193-200.
8. Hamiza O.O., Rehman M.U., Tahir M., Khan R., Khan A.Q., Lateef A., et al. Amelioration of 1,2-dimethylhydrazine (DMH) induced colon oxidative stress, inflammation and tumor promotion response by tannic acid in Wistar rats. Asian Pacific J Cancer Prev 2012, 13:4393-4402.
9. Araujo J.R., Goncalves P., Martel F. Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines. Nutr Res 2011, 31:77-87.
10. Thakur V.S., Deb G., Babcook M.A., Gupta S. Plant phytochemicals as epigenetic modulators: role in cancer chemoprevention. AAPS J 2014, 16:151-163.
11. Wang Y.H., Wang W.Y., Chang C.C., Liou K.T., Sung Y.J., Liao J.F., et al. Protection against cerebral ischemia-reperfusion injury in rats through anti-inflammatory and anti-oxidative effects by taxifolin. J Biomed Sci 2006, 13:127-141.
12. Lee K.Y., Lee K.S., Lee C.H. Antioxidative and antimicrobial effects of taxifolin isolated from a Cactus Cheonnyeoncho (Opuntia humifusa). FASEB J 2007, 21:1083-1084.
13. Zhang Z.R., Al Zaharna M., Wong M.M., Chiu S.K., Cheung H.Y. Taxifolin enhances andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation. Plos One 2013, 8:1-16.
14. Theriault A., Wang Q., Van Iderstine S.C., Chen B., Franke A.A., Adeli K. Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid. J Lipid Res 2000, 4:1969-1979.
15. Arutyunyan T.V., Korystova A.F., Kublik L.N. Effects of taxifolin on the activity of angiotensin-converting enzyme and reactive oxygen and nitrogen species in the aorta of aging rats and rats treated with the nitric oxide synthase inhibitor and dexamethasone. Age 2012, 35:2089-2097.
16. Kim Y.J., Choi S.E., Lee M.W., Lee C.S. Taxifolin glycoside inhibits dendritic cell responses stimulated by lipopolysaccharide and lipoteichoic acid. J Pharm Pharmacol 2008, 60:1465-1472.
17. Sangeetha N., Aranganathan S., Nalini N. Silibinin ameliorates oxidative stress induced aberrant crypt foci and lipid peroxidation in 1, 2 dimethylhydrazine induced rat colon cancer. Invest New Drugs 2010, 28:225-233.
18. Bird R.P. Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett 1995, 93:55-71.
19. Romao-Correa R.F., Maria D.A., Soma M., Sotto M.N., Sanches J.A., Neto C.F., et al. Nucleolar organizer region staining patterns in paraffin embedded tissue cells from human skin cancer. J Cutan Pathol 2005, 32:323-328.
20. Yamada K., Yoshitake K., Sato M., Ahnen D.J. Proliferating cell nuclear antigen expression in normal, preneoplastic, and neoplastic colonic epithelium. Gastroenterology 1992, 103:160-197.
21. Yoshimi N., Morioka T., Kinjo T., Inamine M., Kaneshiro T., Shimizu T., et al. Histological and immunohistochemical observations of mucin-depleted foci (MDF) stained with Alcian blue, in rat colon carcinogenesis induced with 1,2-dimethylhydrazine dihydrochloride. Cancer Sci 2004, 95:792-797.
22. Bancroft J.D., Gamble M. Theory and practice of histological techniques 2008, 85-107. Livingstone, Churchill. 5th ed.
23. Lowry O.H., Rosebrough N.J., Farr L.A., Randall R.J. Protein measurement with the Folin-phenol reagent. J Biol Chem 1951, 193:265-275.
24. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
25. Goldblum S.E., Wu K.M., Jay M. Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits. J Appl Physiol 1985, 59:1978-1985.
26. Rao K.S., Recknagel R.O. Early onset of lipid peroxidation in rat liver after carbon tetrachloride administration. Exp Mol Pathol 1968, 9:271-278.
27. Rotruck J.T., Pope A.L., Ganther H.E., Swanson A.B., Hafeman D.G., Hoekstra W.G. Selenium biochemical role as a component of glutathione peroxidase purification and assay. Science 1973, 179:588-598.
28. Staal G.E., Visser J., Veeger C. Purification and properties of glutathione reductase of human erythrocytes. Biochem Biophys Acta 1969, 185:39-48.
29. Misra H.P., Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 1974, 24:3170-3175.
30. Luck H. Methods in enzymatic analysis 2 1974, 885. Academic Press, New York.
31. Moron M.S., Depierre J.W., Mannervik B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim Biophys Acta 1979, 582:67-78.
32. Bayfield R.K., Cole E.R. Colorimetric estimation of vitamin A with trichloroacetic acid. Methods Enzymol 1980, 67:189-195.
33. Omaye S.T., Turnbull J.D., Sauberlich H.E. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Methods Enzymol 1979, 62:3-11.
34. Desai I.D. Vitamin E analysis method for animal tissues. Methods Enzymol 1984, 105:138-143.
35. Klaunig J.E., Kamendulis L.M., Hocevar B.A. Oxidative stress and oxidative damage in carcinogenesis. Toxicol Pathol 2010, 38:96-109.
36. Perse M., Cerar A. Morphological and molecular alterations in 1,2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats. J Biomed Biotechnol 2011, 2011:1-14.
37. Sengottuvelan M., Senthilkumar R., Nalini N. Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis. Biochim Biophys Acta 2006, 1760:1175-1183.
38. Birt D.F., Hendrich S., Wang W. Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol Ther 2001, 90:157-177.
39. Khare S., Chaudhary K., Bissonnette M., Carroll R. Aberrant crypt foci in colon cancer epidemiology. Methods Mol Biol 2009, 472:373-386.
40. Wargovich M.J., Brownemail V.R., Morris J. Aberrant crypt foci: the case for inclusion as a biomarker for colon cancer. Cancer 2010, 2:1705-1716.
41. Sequetto P.L., Oliveira T.T., Maldonado I.R., Augusto L.E., Mello V.J., Pizziolo V.R., et al. Naringin accelerates the regression of pre-neoplastic lesions and the colorectal structural reorganization in a murine model of chemical carcinogenesis. Food Chem Toxicol 2014, 64:200-209.
42. Wang X.D., Meng M.X., Gao L.B., Liu T., Xu Q., Zeng S. Permeation of astilbin and taxifolin in Caco-2 cell and their effects on the P-gp. Int J Pharm 2009, 378:1-8.
43. Kufe D.W. Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer 2009, 9:874-885.
44. Kim J.J., Khan W.I. Goblet cells and mucins: role in innate defense in enteric infections. Pathogens 2013, 2:55-70.
45. Tanaka T. Colorectal carcinogenesis: review of human and experimental animal studies. J Carcinog 2009, 8:1-19.
46. Manju V., Nalini N. Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis. Cell Biochem Funct 2007, 25:189-194.
47. Panneer Selvam J., Aranganathan S., Nalini N. Aberrant crypt foci and AgNORs as putative biomarkers to evaluate the chemopreventive efficacy of pronyl-lysine in rat colon carcinogenesis. Invest New Drugs 2008, 26:531-540.
48. Roussel P., Hernandez-Verden D. Identification of Ag-NOR proteins, makers of proliferation related to ribosomal gene activity. Exp Cell Res 1994, 214:465-472.
49. Jaafari-Ashkavandi Z., Fatemi F.S. Evaluation of proliferation activity in dysplastic and nondysplastic oral lichen planus through the analysis of argyrophilic nucleolar organizer regions. J Craniofac Surg 2013, 24:788-791.
50. Evan G.I., Vousden K.H. Proliferation, cell cycle and apoptosis in cancer. Nature 2001, 411:342-348.
51. Melen-Mucha G., Niewiadomska H. Frequency of proliferation, apoptosis, and their ratio during rat colon carcinogenesis and their characteristic pattern in the dimethylhydrazine-induced colon adenoma and carcinoma. Cancer Invest 2002, 20:700-712.
52. Bravo R., Frank R., Blundell P.A., Macdonald-Bravo H. Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. Nature 1987, 326:515-517.
53. Tanaka T., Kohno H., Shimada R., Kagami S., Yamaguchi F., Kataoka S., et al. Prevention of colonic aberrant crypt foci by dietary feeding of garcinol in male F344 rats. Carcinogenesis 2000, 21:1183-1189.
54. Liu X., Wang J. Anti-inflammatory effects of iridoid glycosides fraction of Folium syringae leaves on TNBS induced colitis in rats. J Ethnopharmacol 2011, 133:780-787.
55. Droeser R.A., HirtC, Eppenberger-Castori S., Zlobec I., Viehl C.T., Frey D.M., et al. High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor. PlosOne 2013, 8:1-10.
56. Sesti F., Tsitsilonis O.E., Kotsinas A., Trougakos I.P. Oxidative stress-mediated biomolecular damage and inflammation in tumorigenesis. In Vivo 2012, 26:395-402.
57. Ragunath M., Prabu T., Nadanasabapathy S., Revathi R., Manju V. Synergistic and individual effects of umbelliferone with 5-flurouracil on the status of lipid peroxidation and antioxidant defense against 1,2-dimethylhydrazine induced rat colon carcinogenesis. Biomed Prev Nutr 2013, 3:74-82.
58. Khan M.A., Tania M., Zhang D.Z., Chen H.C. Antioxidant enzymes and cancer. Chin J Cancer Res 2010, 22:87-92.
59. Upasani C.D., Khera A., Balaraman R. Effect of Lead and vitamin E, C or spiruline on malondialdehyde, conjugated dienes and hydroperoxides in rats. Ind J Exp Biol 2001, 39:70-74.
60. Burton G.W., Ingold K. Autoxidation of biological molecules. 1. Antioxidant activity of Vitamin E and related chain-breaking phenolic antioxidants in vitro. J Am Chem Soc 1981, 103:64-72.
61. Sun S.Y., Hail N., Lotan R. Apoptosis as a novel target for cancer chemoprevention. J Natl Cancer Inst 2004, 96:662-672.
62. Kaufmann S.H., Earnshaw W.C. Induction of apoptosis by cancer chemotherapy. Exp Cell Res 2000, 256:42-49.