메뉴 건너뛰기




Volumn 23, Issue 16, 2015, Pages 1255-1269

Myeloperoxidase-Hepatocyte-Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 1 A1; CXCL1 CHEMOKINE; HYPOCHLOROUS ACID; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CYTOKINE; PEROXIDASE;

EID: 84946100211     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2014.6108     Document Type: Article
Times cited : (105)

References (56)
  • 1
    • 24044536090 scopus 로고    scopus 로고
    • Recent concepts in non-alcoholic fatty liver disease
    • Adams LA and Angulo P. Recent concepts in non-alcoholic fatty liver disease. Diabet Med 22: 1129-1133, 2005.
    • (2005) Diabet Med , vol.22 , pp. 1129-1133
    • Adams, L.A.1    Angulo, P.2
  • 2
    • 2442624618 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition
    • Alano CC, Ying W, and Swanson RA. Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J Biol Chem 279: 18895-18902, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 18895-18902
    • Alano, C.C.1    Ying, W.2    Swanson, R.A.3
  • 3
    • 79955936155 scopus 로고    scopus 로고
    • Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflamed liver
    • Amanzada A, Malik IA, Nischwitz M, Sultan S, Naz N, and Ramadori G. Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflamed liver. Histochem Cell Biol 135: 305-315, 2011.
    • (2011) Histochem Cell Biol , vol.135 , pp. 305-315
    • Amanzada, A.1    Malik, I.A.2    Nischwitz, M.3    Sultan, S.4    Naz, N.5    Ramadori, G.6
  • 4
    • 0026527581 scopus 로고
    • Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblastlike cells. A potential mechanism of self perpetuation in liver fibrogenesis
    • Bachem MG, Meyer D, Melchior R, Sell KM, and Gressner AM. Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblastlike cells. A potential mechanism of self perpetuation in liver fibrogenesis. J Clin Invest 89: 19-27, 1992.
    • (1992) J Clin Invest , vol.89 , pp. 19-27
    • Bachem, M.G.1    Meyer, D.2    Melchior, R.3    Sell, K.M.4    Gressner, A.M.5
  • 6
    • 66749106254 scopus 로고    scopus 로고
    • Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD)
    • Bellentani S and Marino M. Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD). Ann Hepatol 8 Suppl 1: S4-S8, 2009.
    • (2009) Ann Hepatol , vol.8 , pp. S4-S8
    • Bellentani, S.1    Marino, M.2
  • 7
    • 58149311010 scopus 로고    scopus 로고
    • Isolation of murine intrahepatic immune cells employing a modified procedure for mechanical disruption and functional characterization of the B, T and natural killer T cells obtained
    • Blom KG, Qazi MR, Matos JB, Nelson BD, DePierre JW, and Abedi-Valugerdi M. Isolation of murine intrahepatic immune cells employing a modified procedure for mechanical disruption and functional characterization of the B, T and natural killer T cells obtained. Clin Exp Immunol 155: 320-329, 2009.
    • (2009) Clin Exp Immunol , vol.155 , pp. 320-329
    • Blom, K.G.1    Qazi, M.R.2    Matos, J.B.3    Nelson, B.D.4    DePierre, J.W.5    Abedi-Valugerdi, M.6
  • 8
    • 33645660479 scopus 로고    scopus 로고
    • EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death
    • Carmona-Cuenca I, Herrera B, Ventura JJ, Roncero C, Fernandez M, and Fabregat I. EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death. J Cell Physiol 207: 322-330, 2006.
    • (2006) J Cell Physiol , vol.207 , pp. 322-330
    • Carmona-Cuenca, I.1    Herrera, B.2    Ventura, J.J.3    Roncero, C.4    Fernandez, M.5    Fabregat, I.6
  • 9
    • 33645405910 scopus 로고    scopus 로고
    • Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates
    • Chen JW, Querol Sans M, Bogdanov A, Jr., Weissleder R. Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates. Radiology 240: 473-481, 2006.
    • (2006) Radiology , vol.240 , pp. 473-481
    • Chen, J.W.1    Querol Sans, M.2    Bogdanov, A.3    Weissleder, R.4
  • 10
    • 4043066518 scopus 로고    scopus 로고
    • Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: Potential role of poly(ADP-ribose) polymerase-1
    • Chen M, Zsengeller Z, Xiao CY, and Szabo C. Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly(ADP-ribose) polymerase-1. Cardiovasc Res 63: 682-688, 2004.
    • (2004) Cardiovasc Res , vol.63 , pp. 682-688
    • Chen, M.1    Zsengeller, Z.2    Xiao, C.Y.3    Szabo, C.4
  • 14
    • 4644297019 scopus 로고    scopus 로고
    • Natural history of nonalcoholic steatohepatitis: A longitudinal study of repeat liver biopsies
    • Fassio E, Alvarez E, Dominguez N, Landeira G, and Longo C. Natural history of nonalcoholic steatohepatitis: a longitudinal study of repeat liver biopsies. Hepatology 40: 820-826, 2004.
    • (2004) Hepatology , vol.40 , pp. 820-826
    • Fassio, E.1    Alvarez, E.2    Dominguez, N.3    Landeira, G.4    Longo, C.5
  • 16
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 88: 125-172, 2008.
    • (2008) Physiol Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 20
    • 3042634915 scopus 로고    scopus 로고
    • NADPH oxidase-derived oxidant stress is critical for neutrophil cytotoxicity during endotoxemia
    • Gujral JS, Hinson JA, Farhood A, and Jaeschke H. NADPH oxidase-derived oxidant stress is critical for neutrophil cytotoxicity during endotoxemia. Am J Physiol Gastrointest Liver Physiol 287: G243-G252, 2004.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , pp. G243-G252
    • Gujral, J.S.1    Hinson, J.A.2    Farhood, A.3    Jaeschke, H.4
  • 22
    • 0029891492 scopus 로고    scopus 로고
    • Identification of factors from rat neutrophils responsible for cytotoxicity to isolated hepatocytes
    • Ho JS, Buchweitz JP, Roth RA, and Ganey PE. Identification of factors from rat neutrophils responsible for cytotoxicity to isolated hepatocytes. J Leukoc Biol 59: 716-724, 1996.
    • (1996) J Leukoc Biol , vol.59 , pp. 716-724
    • Ho, J.S.1    Buchweitz, J.P.2    Roth, R.A.3    Ganey, P.E.4
  • 23
    • 18244390487 scopus 로고    scopus 로고
    • Myeloperoxidase: Friend and foe
    • Klebanoff SJ. Myeloperoxidase: friend and foe. J Leukoc Biol 77: 598-625, 2005.
    • (2005) J Leukoc Biol , vol.77 , pp. 598-625
    • Klebanoff, S.J.1
  • 26
    • 0031713092 scopus 로고    scopus 로고
    • Clinical manifestation of myeloperoxidase deficiency
    • Lanza F. Clinical manifestation of myeloperoxidase deficiency. J Mol Med (Berl) 76: 676-681, 1998.
    • (1998) J Mol Med (Berl) , vol.76 , pp. 676-681
    • Lanza, F.1
  • 27
    • 0020318185 scopus 로고
    • Hepatic Vitamin A depletion in alcoholic liver injury
    • Leo MA and Lieber CS. Hepatic vitamin A depletion in alcoholic liver injury. N Engl J Med 307: 597-601, 1982.
    • (1982) N Engl J Med , vol.307 , pp. 597-601
    • Leo, M.A.1    Lieber, C.S.2
  • 28
    • 0032862560 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat
    • Marra F, Arrighi MC, Fazi M, Caligiuri A, Pinzani M, Romanelli RG, Efsen E, Laffi G, and Gentilini P. Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat. Hepatology 30: 951-958, 1999.
    • (1999) Hepatology , vol.30 , pp. 951-958
    • Marra, F.1    Arrighi, M.C.2    Fazi, M.3    Caligiuri, A.4    Pinzani, M.5    Romanelli, R.G.6    Efsen, E.7    Laffi, G.8    Gentilini, P.9
  • 29
    • 80355129001 scopus 로고    scopus 로고
    • Seven steps to stellate cells
    • Maschmeyer P, Flach M, and Winau F. Seven steps to stellate cells. J Vis Exp 51: pii: 2710, 2011.
    • (2011) J Vis Exp , vol.51 , pp. 2710
    • Maschmeyer, P.1    Flach, M.2    Winau, F.3
  • 32
    • 0035179839 scopus 로고    scopus 로고
    • DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells
    • Olaso E, Ikeda K, Eng FJ, Xu L, Wang LH, Lin HC, and Friedman SL. DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells. J Clin Invest 108: 1369-1378, 2001.
    • (2001) J Clin Invest , vol.108 , pp. 1369-1378
    • Olaso, E.1    Ikeda, K.2    Eng, F.J.3    Xu, L.4    Wang, L.H.5    Lin, H.C.6    Friedman, S.L.7
  • 35
    • 0034057158 scopus 로고    scopus 로고
    • Stress-activated protein kinases in the activation of rat hepatic stellate cells in culture
    • Reeves HL, Dack CL, Peak M, Burt AD, and Day CP. Stress-activated protein kinases in the activation of rat hepatic stellate cells in culture. J Hepatol 32: 465-472, 2000.
    • (2000) J Hepatol , vol.32 , pp. 465-472
    • Reeves, H.L.1    Dack, C.L.2    Peak, M.3    Burt, A.D.4    Day, C.P.5
  • 36
    • 0037424498 scopus 로고    scopus 로고
    • The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type i collagen expression
    • Reif S, Lang A, Lindquist JN, Yata Y, Gabele E, Scanga A, Brenner DA, and Rippe RA. The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression. J Biol Chem 278: 8083-8090, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 8083-8090
    • Reif, S.1    Lang, A.2    Lindquist, J.N.3    Yata, Y.4    Gabele, E.5    Scanga, A.6    Brenner, D.A.7    Rippe, R.A.8
  • 37
    • 84903988705 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species in steatotic hepatocytes: A molecular perspective on the pathophysiology of ischemia-reperfusion injury in the fatty liver
    • Reiniers MJ, van Golen RF, van Gulik TM, and Heger M. Reactive oxygen and nitrogen species in steatotic hepatocytes: a molecular perspective on the pathophysiology of ischemia-reperfusion injury in the fatty liver. Antioxid Redox Signal 21: 1119-1142, 2014.
    • (2014) Antioxid Redox Signal , vol.21 , pp. 1119-1142
    • Reiniers, M.J.1    Van Golen, R.F.2    Van Gulik, T.M.3    Heger, M.4
  • 40
    • 0030882523 scopus 로고    scopus 로고
    • Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion
    • Rowell DL, Eckmann L, Dwinell MB, Carpenter SP, Raucy JL, Yang SK, and Kagnoff MF. Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion. Am J Physiol 273: G322-G332, 1997.
    • (1997) Am J Physiol , vol.273 , pp. G322-G332
    • Rowell, D.L.1    Eckmann, L.2    Dwinell, M.B.3    Carpenter, S.P.4    Raucy, J.L.5    Yang, S.K.6    Kagnoff, M.F.7
  • 43
    • 0035991444 scopus 로고    scopus 로고
    • In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
    • Seki S, Kitada T, Yamada T, Sakaguchi H, Nakatani K, and Wakasa K. In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases. J Hepatol 37: 56-62, 2002.
    • (2002) J Hepatol , vol.37 , pp. 56-62
    • Seki, S.1    Kitada, T.2    Yamada, T.3    Sakaguchi, H.4    Nakatani, K.5    Wakasa, K.6
  • 44
    • 14744280934 scopus 로고    scopus 로고
    • Scavenger effect of flavonols on HOCl-induced luminol chemiluminescence
    • Selloum L, Djelili H, Sebihi L, and Arnhold J. Scavenger effect of flavonols on HOCl-induced luminol chemiluminescence. Luminescence 19: 199-204, 2004.
    • (2004) Luminescence , vol.19 , pp. 199-204
    • Selloum, L.1    Djelili, H.2    Sebihi, L.3    Arnhold, J.4
  • 45
    • 34249789027 scopus 로고    scopus 로고
    • Regulation of hepatocyte apoptosis by oxidative stress
    • Singh R and Czaja MJ. Regulation of hepatocyte apoptosis by oxidative stress. J Gastroenterol Hepatol 22 Suppl 1: S45-S48, 2007.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. S45-S48
    • Singh, R.1    Czaja, M.J.2
  • 46
    • 34547673497 scopus 로고    scopus 로고
    • Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
    • Szabo C, Ischiropoulos H, and Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 6: 662-680, 2007.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 662-680
    • Szabo, C.1    Ischiropoulos, H.2    Radi, R.3
  • 48
    • 48649104386 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in liver ischemia and reperfusion: Role of c-Jun N-terminal kinase 2
    • Theruvath TP, Snoddy MC, Zhong Z, and Lemasters JJ. Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2. Transplantation 85: 1500-1504, 2008.
    • (2008) Transplantation , vol.85 , pp. 1500-1504
    • Theruvath, T.P.1    Snoddy, M.C.2    Zhong, Z.3    Lemasters, J.J.4
  • 50
    • 10044265209 scopus 로고    scopus 로고
    • JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
    • Ventura JJ, Cogswell P, Flavell RA, Baldwin AS, Jr., Davis RJ. JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev 18: 2905-2915, 2004.
    • (2004) Genes Dev , vol.18 , pp. 2905-2915
    • Ventura, J.J.1    Cogswell, P.2    Flavell, R.A.3    Baldwin, A.S.4    Davis, R.J.5
  • 51
    • 84895777018 scopus 로고    scopus 로고
    • Mechanistic characterization of a 2-thioxanthine myeloperoxidase inhibitor and selectivity assessment utilizing click chemistry-activitybased protein profiling
    • Ward J, Spath SN, Pabst B, Carpino PA, Ruggeri RB, Xing G, Speers AE, Cravatt BF, and Ahn K. Mechanistic characterization of a 2-thioxanthine myeloperoxidase inhibitor and selectivity assessment utilizing click chemistry-activitybased protein profiling. Biochemistry 52: 9187-9201, 2013.
    • (2013) Biochemistry , vol.52 , pp. 9187-9201
    • Ward, J.1    Spath, S.N.2    Pabst, B.3    Carpino, P.A.4    Ruggeri, R.B.5    Xing, G.6    Speers, A.E.7    Cravatt, B.F.8    Ahn, K.9
  • 52
    • 0029829455 scopus 로고    scopus 로고
    • Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
    • Weltman MD, Farrell GC, and Liddle C. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology 111: 1645-1653, 1996.
    • (1996) Gastroenterology , vol.111 , pp. 1645-1653
    • Weltman, M.D.1    Farrell, G.C.2    Liddle, C.3
  • 54
    • 84893636304 scopus 로고    scopus 로고
    • Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice
    • Yang L, Roh YS, Song J, Zhang B, Liu C, Loomba R, and Seki E. Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice. Hepatology 59: 483-495, 2014.
    • (2014) Hepatology , vol.59 , pp. 483-495
    • Yang, L.1    Roh, Y.S.2    Song, J.3    Zhang, B.4    Liu, C.5    Loomba, R.6    Seki, E.7
  • 55
    • 84878462333 scopus 로고    scopus 로고
    • Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles
    • Zhang N, Francis KP, Prakash A, and Ansaldi D. Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles. Nat Med 19: 500-505, 2013.
    • (2013) Nat Med , vol.19 , pp. 500-505
    • Zhang, N.1    Kp, F.2    Prakash, A.3    Ansaldi, D.4
  • 56
    • 0038368985 scopus 로고    scopus 로고
    • Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: Potential implications in intracellular fluorescence detection of superoxide
    • Zhao H, Kalivendi S, Zhang H, Joseph J, Nithipatikom K, Vasquez-Vivar J, and Kalyanaraman B. Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide. Free Radic Biol Med 34: 1359-1368, 2003.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1359-1368
    • Zhao, H.1    Kalivendi, S.2    Zhang, H.3    Joseph, J.4    Nithipatikom, K.5    Vasquez-Vivar, J.6    Kalyanaraman, B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.