Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: Potential role of poly(ADP-ribose) polymerase-1

Cardiovascular Research

Volumn 63, Issue 4, 2004, Pages 682-688

  Chen, Min ^a   Zsengellér, Zsuzsanna ^a   Xiao, Chun Yang ^a   Szabó, Csaba ^a  

^a INOTEK CORPORATION   (United States)

Author keywords

Apoptosis; DNA; Heart; Necrosis; Oxidative stress

Indexed keywords

APOPTOSIS INDUCING FACTOR; CYTOCHROME C; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OXIDIZING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR DISEASE; CELL DEATH; CELL FUNCTION; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; HEART MUSCLE CELL; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; WILD TYPE;

ANIMALS; APOPTOSIS INDUCING FACTOR; BIOLOGICAL TRANSPORT; CELL NUCLEUS; CELLS, CULTURED; CYTOCHROMES C; FLAVOPROTEINS; MALE; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS;

EID: 4043066518     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2004.04.018     Document Type: Article

References (27)

1. Virag L., Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol. Rev. 54:2002;375-429
2. Thiemermann C., Bowes J., Myint F.P., Vane J.R. Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle. Proc. Natl. Acad. Sci. U. S. A. 94:1997;679-683
3. Zingarelli B., Salzman A.L., Szabo C. Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. Circ. Res. 83:1998;85-94
4. Szabados E., Fischer G.M., Toth K., et al. Role of reactive oxygen species and poly-ADP-ribose polymerase in the development of AZT-induced cardiomyopathy in rat. Free Radic. Biol. Med. 26:1999;309-317
5. Pacher P., Liaudet L., Mabley J., Komjati K., Szabo C. Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure. J. Am. Coll. Cardiol. 40:2002;1006-1016
6. Virag L., Salzman A.L., Szabo C. Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death. J. Immunol. 161:1998;3753-3759
7. Halmosi R., Berente Z., Osz E., et al. Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system. Mol. Pharmacol. 59:2001;1497-1505
8. Klaidman L.K., Yang J., Chang M.L., Adams J.D. Jr. Recent developments on the role of mitochondria in poly(ADP-ribose) polymerase inhibition. Curr. Med. Chem. 10:2003;2669-2678
9. Du L., Zhang X., Han Y.Y., et al. Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress. J. Biol. Chem. 278:2003;18426-18433
10. Yu S.W., Wang H., Poitras M.F., et al. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science. 297:2002;259-263
11. Zhou Y.Y., Wang S.Q., Zhu W.Z., et al. Culture and adenoviral infection of adult mouse cardiac myocytes: methods for cellular genetic physiology. Am. J. Physiol. Heart Circ. Physiol. 279:2000;H429-H436
12. Wang Z.Q., Auer B., Stingl L., et al. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev. 9:1995;509-520
13. Hinz M., Katsilambros N., Maier V., Schatz H., Pfeiffer E.F. Significance of streptozotocin induced nicotinamide-adenine-dinucleotide (NAD) degradation in mouse pancreatic islets. FEBS Lett. 30:1973;225-228
14. Smiley S.T., Reers M., Mottola-Hartshorn C., et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc. Natl. Acad. Sci. U. S. A. 88:1991;3671-3675
15. Gilad E., Zingarelli B., Salzman A.L., Szabo C. Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts in vitro. J. Mol. Cell Cardiol. 29:1997;2585-2597
16. Bowes J., Piper J., Thiemermann C. Inhibitors of the activity of poly (ADP-ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts. Br. J. Pharmacol. 124:1998;1760-1766
17. Southan G.J., Szabo C. Poly(ADP-ribose) polymerase inhibitors. Curr. Med. Chem. 10:2003;321-340
18. Czapski G.A., Cakala M., Kopczuk D., Strosznajder J.B. Effect of poly(ADP-ribose) polymerase inhibitors on oxidative stress evoked hydroxyl radical level and macromolecules oxidation in cell free system of rat brain cortex. Neurosci. Lett. 356:2004;45-48
19. Grupp I.L., Jackson T.M., Hake P., Grupp G., Szabo C. Protection against hypoxia-reoxygenation in the absence of poly (ADP-ribose) synthetase in isolated working hearts. J. Mol. Cell Cardiol. 31:1999;297-303
20. Pieper A.A., Walles T., Wei G., et al. Myocardial postischemic injury is reduced by polyADPribose polymerase-1 gene disruption. Mol. Med. 6:2000;271-282
21. Zingarelli B., Hake P.W., O'Connor M., et al. Absence of poly(ADP-ribose)polymerase-1 alters nuclear factor-kappa B activation and gene expression of apoptosis regulators after reperfusion injury. Mol. Med. 9:2003;143-153
22. Cregan S.P., Fortin A., MacLaurin J.G., et al. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J. Cell Biol. 158:2002;507-517
23. Kim G.T., Chun Y.S., Park J.W., Kim M.S. Role of apoptosis-inducing factor in myocardial cell death by ischemia-reperfusion. Biochem. Biophys. Res. Commun. 309:2003;619-624
24. Varbiro G., Toth A., Tapodi A., et al. Protective effect of amiodarone but not N-desethylamiodarone on postischemic hearts through the inhibition of mitochondrial permeability transition. J. Pharmacol. Exp. Ther. 307:2003;615-625
25. Alano C.C., Ying W., Swanson R.A. Poly(ADP-ribose) polymerase-1 mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J.Biol. Chem. 279:2004;18895-18902
26. Du X., Matsumura T., Edelstein D., et al. Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J. Clin. Invest. 112:2003;1049-1057
27. Komjáti K., Mabley J.G., Virág L., et al. Poly(ADP-ribose) polymerase inhibition protects neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke. Int. J. Mol. Med. 13:2004;373-382