The epigenome, 4D nucleome and next-generation neuropsychiatric pharmacogenomics

Pharmacogenomics

Volumn 16, Issue 14, 2015, Pages 1649-1669

  Higgins, Gerald A ^a,b   Allyn Feuer, Ari ^b   Handelman, Samuel ^c   Sadee, Wolfgang ^c   Athey, Brian D ^b  

^a Assurex Health   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

allelic imbalance; biochronicity; candidate genes; chromatin interaction networks; CNS; genome wide association studies; GWAS; long noncoding RNAs; noncoding gene variants; pathway analysis; pharmacoepigenomics; psychotropic medications; super resolution microscopy; transcription factors

Indexed keywords

AMITRIPTYLINE; ARIPIPRAZOLE; ATOMOXETINE; CARBAMAZEPINE; CITALOPRAM; CLOBAZAM; CLOZAPINE; CODEINE; CYTOCHROME P450 2D6; DESIPRAMINE; DEXTROMETHORPHAN PLUS QUINIDINE; DIAZEPAM; DOXEPIN; FLUOXETINE; GALANTAMINE; ILOPERIDONE; IMIPRAMINE; LONG UNTRANSLATED RNA; MODAFINIL; NEFAZODONE; NORTRIPTYLINE; PAROXETINE; PERPHENAZINE; PHENYTOIN; PIMOZIDE; PROTRIPTYLINE; RISPERIDONE; TETRABENAZINE; THIORIDAZINE; UNINDEXED DRUG; PSYCHOTROPIC AGENT;

AMINO ACID SEQUENCE; CELL NUCLEUS; CHROMOSOME; CHRONICITY; COPY NUMBER VARIATION; DRUG RESPONSE; EPIGENETICS; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN GENOME; IMMUNOPRECIPITATION; MENTAL DISEASE; NEUROLOGIC DISEASE; NEUROPSYCHIATRY; NEXT GENERATION SEQUENCING; PAIN; PHARMACOGENOMICS; PHENOTYPE; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; GENETIC EPIGENESIS; GENETICS; MENTAL DISORDERS; PHARMACOGENETICS; TRENDS;

EPIGENESIS, GENETIC; EPIGENOMICS; GENOME, HUMAN; HUMANS; MENTAL DISORDERS; PHARMACOGENETICS; PSYCHOTROPIC DRUGS;

EID: 84945559214     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.15.111     Document Type: Review

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