-
1
-
-
0026468707
-
HLA-associations in Leponex/Clozaril (Clozapine)-induced granulocytopenia and agranulocytosis
-
Abt K, Gulich A, Krupp P, Reinberg W. HLA-associations in Leponex/Clozaril (Clozapine)-induced granulocytopenia and agranulocytosis. Drug Saf 1992: 7: 10-6.
-
(1992)
Drug Saf
, vol.7
, pp. 10-16
-
-
Abt, K.1
Gulich, A.2
Krupp, P.3
Reinberg, W.4
-
3
-
-
0000124912
-
Neutropenia and neutrophilia
-
Beutler E, Coller BS, Marshall AL, Kipps TJ, Seligsohn U, eds. USA: McGraw-Hill companies, Medical publishing division
-
Dale DC. Neutropenia and neutrophilia. In: Beutler E, Coller BS, Marshall AL, Kipps TJ, Seligsohn U, eds. Williams Hematology, 6th edn. USA: McGraw-Hill companies, Medical publishing division, 2001, 827-8.
-
(2001)
Williams Hematology, 6th Edn.
, pp. 827-828
-
-
Dale, D.C.1
-
4
-
-
0030278639
-
Clozapine and agranulocytosis
-
Feldmen J. Clozapine and agranulocytosis. Psychiatr Serv 1996: 47: 1177-8.
-
(1996)
Psychiatr Serv
, vol.47
, pp. 1177-1178
-
-
Feldmen, J.1
-
5
-
-
0025599851
-
Clozapine. A review of its pharmacological properties, and therapeutic use in schizophrenia
-
Fitton A & Heel RC. Clozapine. A review of its pharmacological properties, and therapeutic use in schizophrenia. Drugs 1990: 40: 722-47.
-
(1990)
Drugs
, vol.40
, pp. 722-747
-
-
Fitton, A.1
Heel, R.C.2
-
6
-
-
0031770078
-
Examination of possible toxic and immune mechanisms of clozapine-induced agranulocytosis
-
Guest I, Sokoluk B, MacCrimmon J, Uetrecht J. Examination of possible toxic and immune mechanisms of clozapine-induced agranulocytosis. Toxicology 1998: 131: 53-65.
-
(1998)
Toxicology
, vol.131
, pp. 53-65
-
-
Guest, I.1
Sokoluk, B.2
MacCrimmon, J.3
Uetrecht, J.4
-
7
-
-
0344043698
-
Mechanisms of clozapine-induced agranulocytosis
-
Gerson SL & Meltzre H. Mechanisms of clozapine-induced agranulocytosis. Drug Saf 1992: 7: 17-25.
-
(1992)
Drug Saf
, vol.7
, pp. 17-25
-
-
Gerson, S.L.1
Meltzre, H.2
-
8
-
-
0032933969
-
The cytotoxicity of the clozapine metabolites: Implications for predicting clozapine-induced agranulocytosis
-
Tschen AC, Rieder MJ, Oyewumi LK, Freeman DJ. The cytotoxicity of the clozapine metabolites: implications for predicting clozapine-induced agranulocytosis. Clin Pharmacol Ther 1999: 65: 526-32.
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 526-532
-
-
Tschen, A.C.1
Rieder, M.J.2
Oyewumi, L.K.3
Freeman, D.J.4
-
9
-
-
0029555342
-
Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells
-
Liu ZC & Uetrecht J. Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells. J Pharmacol Exp Ther 1995: 275: 1476-83.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 1476-1483
-
-
Liu, Z.C.1
Uetrecht, J.2
-
10
-
-
0028176651
-
Oxidative stress as a mediator of apoptosis
-
Buttke TM & Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994: 15: 7-10.
-
(1994)
Immunol Today
, vol.15
, pp. 7-10
-
-
Buttke, T.M.1
Sandstrom, P.A.2
-
12
-
-
0026490658
-
On the possible mechanisms and predictability of clozapine-induced agranulocytosis
-
Pisciotta AV, Konings SA, Ciesemier LL, Cronkite CE, Liebermann JA. On the possible mechanisms and predictability of clozapine-induced agranulocytosis. Drug Saf 1992: 7: 33-44.
-
(1992)
Drug Saf
, vol.7
, pp. 33-44
-
-
Pisciotta, A.V.1
Konings, S.A.2
Ciesemier, L.L.3
Cronkite, C.E.4
Liebermann, J.A.5
-
13
-
-
0029841755
-
Reactive metabolites and agranulocytosis
-
Uetrecht JP. Reactive metabolites and agranulocytosis. Eur J Haematol 1996: 57: 83-8.
-
(1996)
Eur J Haematol
, vol.57
, pp. 83-88
-
-
Uetrecht, J.P.1
-
14
-
-
0031471159
-
Neutrophil cytotoxicity of the chemically reactive metabolite(s) of clozapine: Possible role in agranulocytosis
-
Williams DP, Pirmohamed M, Naisbitt DJ, Maggs JS, Park BK. Neutrophil cytotoxicity of the chemically reactive metabolite(s) of clozapine: possible role in agranulocytosis. J Pharmacol Exp Ther 1997: 283: 1375-82.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1375-1382
-
-
Williams, D.P.1
Pirmohamed, M.2
Naisbitt, D.J.3
Maggs, J.S.4
Park, B.K.5
-
15
-
-
0025175183
-
HLA-B38, DR4, DQw3 and clozapine-induced agranulocytosis in Jewish patients with schizophrenia
-
Lieberman JA, Yunis J, Egea E, Canoso RT, Kane JM, Yunis EJ. HLA-B38, DR4, DQw3 and clozapine-induced agranulocytosis in Jewish patients with schizophrenia. Arch Gen Psychiatry 1990: 47: 945-8.
-
(1990)
Arch Gen Psychiatry
, vol.47
, pp. 945-948
-
-
Lieberman, J.A.1
Yunis, J.2
Egea, E.3
Canoso, R.T.4
Kane, J.M.5
Yunis, E.J.6
-
16
-
-
85046529781
-
Genetic determinants of clozapine-induced agranulocytosis: Recent results of HLa subtyping in a non-Jewish Caucasian sample
-
Dettling M & Cascorbi I. Genetic determinants of clozapine-induced agranulocytosis: recent results of HLA subtyping in a non-Jewish Caucasian sample. Arch Gen Psychiatry 2001: 58: 3-4.
-
(2001)
Arch Gen Psychiatry
, vol.58
, pp. 3-4
-
-
Dettling, M.1
Cascorbi, I.2
-
17
-
-
0031965777
-
HLA-B38 and clozapine-induced agranulocytosis in Israeli Jewish schizophrenic patients
-
Valevski A, Klein T, Gazit E et al. HLA-B38 and clozapine-induced agranulocytosis in Israeli Jewish schizophrenic patients. Eur J Immunogenet 1998: 25: 11-3.
-
(1998)
Eur J Immunogenet
, vol.25
, pp. 11-13
-
-
Valevski, A.1
Klein, T.2
Gazit, E.3
-
18
-
-
0026493449
-
Major histocompatibility complex associations with clozapine-induced agranulocytosis
-
Yunis JJ, Lieberman J, Yunis ED. Major histocompatibility complex associations with clozapine-induced agranulocytosis. Drug Saf 1992: 7: 7-9.
-
(1992)
Drug Saf
, vol.7
, pp. 7-9
-
-
Yunis, J.J.1
Lieberman, J.2
Yunis, E.D.3
-
19
-
-
0029135344
-
HLA associations in clozapine-induced agranulocytosis
-
Yunis JJ, Corzo D, Salazar M, Lieberman J, Howard A, Yunis ED. HLA associations in clozapine-induced agranulocytosis. Blood 1995: 86: 1177-83.
-
(1995)
Blood
, vol.86
, pp. 1177-1183
-
-
Yunis, J.J.1
Corzo, D.2
Salazar, M.3
Lieberman, J.4
Howard, A.5
Yunis, E.D.6
-
20
-
-
0027967729
-
HSP70-2 9.0kb variant is in linkage disequilibrium with the HLA-B and DRB1* alleles associated with clozapine-induced agranulocytosis
-
Corzo D, Yunis JJ, Yunis EJ, Howard A, Lieberman JA. HSP70-2 9.0kb variant is in linkage disequilibrium with the HLA-B and DRB1* alleles associated with clozapine-induced agranulocytosis. J Clin Psychiatry 1994: 55 (Suppl. B): 149-52.
-
(1994)
J Clin Psychiatry
, vol.55
, Issue.SUPPL. B
, pp. 149-152
-
-
Corzo, D.1
Yunis, J.J.2
Yunis, E.J.3
Howard, A.4
Lieberman, J.A.5
-
21
-
-
0028820611
-
The major histocompatibility complex region marked by HSP70-1 and HSP70-2 variants is associated with clozapine-induced agranulocytosis in two different ethnic groups
-
Corzo D, Yunis JJ, Salazar M et al. The major histocompatibility complex region marked by HSP70-1 and HSP70-2 variants is associated with clozapine-induced agranulocytosis in two different ethnic groups. Blood 1995: 86: 3835-40.
-
(1995)
Blood
, vol.86
, pp. 3835-3840
-
-
Corzo, D.1
Yunis, J.J.2
Salazar, M.3
-
22
-
-
0028318860
-
Human NAD(P)H: Quinone oxidoreductase 2. Gene structure, activity, and tissue-specific expression
-
Jaiswal AK. Human NAD(P)H: quinone oxidoreductase 2. Gene structure, activity, and tissue-specific expression. J Biol Chem 1994: 269: 14502-8.
-
(1994)
J Biol Chem
, vol.269
, pp. 14502-14508
-
-
Jaiswal, A.K.1
-
23
-
-
0033805383
-
Structure-function studies of DT-diaphorase (NQO1) and NRH: Quinone oxidoreductase (NQO2)
-
Chen S, Wu K, Knox R. Structure-function studies of DT-diaphorase (NQO1) and NRH: quinone oxidoreductase (NQO2). Free Radic Biol Med 2000: 29: 276-84.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 276-284
-
-
Chen, S.1
Wu, K.2
Knox, R.3
-
24
-
-
0033800922
-
Regulation of genes encoding NAD(P)H: Quinone oxidoreductases
-
Jaiswal AK. Regulation of genes encoding NAD(P)H: quinone oxidoreductases. Free Radic Biol Med 2000: 29: 254-62.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 254-262
-
-
Jaiswal, A.K.1
-
25
-
-
0034527964
-
NRH: Quinone oxidoreductase 2 (NQO2)
-
Long DJ & Jaiswal AK. NRH: quinone oxidoreductase 2 (NQO2). Chem Biol Interact 2000: 129: 99-112.
-
(2000)
Chem Biol Interact
, vol.129
, pp. 99-112
-
-
Long, D.J.1
Jaiswal, A.K.2
-
26
-
-
0029778731
-
Technical aspects of quantitative competitive PCR
-
Zimmermann K & Mannhalter JW. Technical aspects of quantitative competitive PCR. Biotechniques 1996: 21: 268-79.
-
(1996)
Biotechniques
, vol.21
, pp. 268-279
-
-
Zimmermann, K.1
Mannhalter, J.W.2
-
27
-
-
0035034244
-
Catalog of 320 single nucleotide polymorphisms (SNPs) in 20 quinone oxidoreductase and sulfotransferase genes
-
Iida A, Sekine A, Saito S et al. Catalog of 320 single nucleotide polymorphisms (SNPs) in 20 quinone oxidoreductase and sulfotransferase genes. J Hum Genet 2001: 46: 225-40.
-
(2001)
J Hum Genet
, vol.46
, pp. 225-240
-
-
Iida, A.1
Sekine, A.2
Saito, S.3
-
28
-
-
0035834571
-
An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes: Glutathione S-transferase M1 and quinone oxidoreductase 1 and 2
-
Harada S, Fujii C, Hayashi A, Ohkoshi N. An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes: glutathione S-transferase M1 and quinone oxidoreductase 1 and 2. Biochem Biophys Res Commun 2001: 288: 887-92.
-
(2001)
Biochem Biophys Res Commun
, vol.288
, pp. 887-892
-
-
Harada, S.1
Fujii, C.2
Hayashi, A.3
Ohkoshi, N.4
-
29
-
-
0035822806
-
2+- and cyclic AMP-dependent gene transcription
-
2+-and cyclic AMP-dependent gene transcription. Sci STKE 2001: 94: PE1.
-
(2001)
Sci STKE
, vol.94
-
-
Finkbeiner, S.1
-
30
-
-
0031972862
-
Illegitimate transcription: Its use for studying genetic abnormalities in lymphoblastoid cells from patients with Glanzmann thrombasthenia
-
Negrier C, Vinciguerra C, Attali O, Grenier C, Larcher ME, Dechavanne M. Illegitimate transcription: its use for studying genetic abnormalities in lymphoblastoid cells from patients with Glanzmann thrombasthenia. Br J Haematol 1998: 100: 33-9.
-
(1998)
Br J Haematol
, vol.100
, pp. 33-39
-
-
Negrier, C.1
Vinciguerra, C.2
Attali, O.3
Grenier, C.4
Larcher, M.E.5
Dechavanne, M.6
-
31
-
-
0031573462
-
Catalytic properties of NAD(P)H: Quinone oxidoreductase 2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase
-
Wu K, Knox R, Sun XZ et al. Catalytic properties of NAD(P)H: quinone oxidoreductase 2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase. Arch Biochem Biophys 1997: 347: 221-8.
-
(1997)
Arch Biochem Biophys
, vol.347
, pp. 221-228
-
-
Wu, K.1
Knox, R.2
Sun, X.Z.3
-
32
-
-
0036709821
-
TNF-α and -β gene polymorphisms in multiple sclerosis: A highly significant role for determinants in the first intron of the TNF-β gene
-
Americo J, Filho F, Vedeler CA, Myhr KM, Nyland H, Pandey J. TNF-α and -β gene polymorphisms in multiple sclerosis: A highly significant role for determinants in the first intron of the TNF-β gene. Autoimmunity 2002: 35: 377-80.
-
(2002)
Autoimmunity
, vol.35
, pp. 377-380
-
-
Americo, J.1
Filho, F.2
Vedeler, C.A.3
Myhr, K.M.4
Nyland, H.5
Pandey, J.6
-
33
-
-
0036911605
-
Distribution and characterization of regulatory elements in the human genome
-
Majewski J & Ott J. Distribution and characterization of regulatory elements in the human genome. Genome Res 2002: 12: 1827-36.
-
(2002)
Genome Res
, vol.12
, pp. 1827-1836
-
-
Majewski, J.1
Ott, J.2
-
34
-
-
0030854907
-
Transcription factors, normal development, and leukemia
-
Tenen DG, Hromas R, Licht JD, Zhang DE. Transcription factors, normal development, and leukemia. Blood 1997: 90: 489-519.
-
(1997)
Blood
, vol.90
, pp. 489-519
-
-
Tenen, D.G.1
Hromas, R.2
Licht, J.D.3
Zhang, D.E.4
-
35
-
-
0032781973
-
Resistance to apoptosis in human cells conferred by telomerase function and telomere stability
-
Holt SE, Glinsky VV, Ivanova AB, Glinsky GV. Resistance to apoptosis in human cells conferred by telomerase function and telomere stability. Mol Carcinog 1999: 25: 241-8.
-
(1999)
Mol Carcinog
, vol.25
, pp. 241-248
-
-
Holt, S.E.1
Glinsky, V.V.2
Ivanova, A.B.3
Glinsky, G.V.4
-
37
-
-
0028944753
-
Metabolism and bioactivation of clozapine by human liver in vitro
-
Pirmohamed M, Williams D, Madden S, Templeton E, Park BK. Metabolism and bioactivation of clozapine by human liver in vitro. J Pharmacol Exp Ther 1995: 272: 984-90.
-
(1995)
J Pharmacol Exp Ther
, vol.272
, pp. 984-990
-
-
Pirmohamed, M.1
Williams, D.2
Madden, S.3
Templeton, E.4
Park, B.K.5
-
38
-
-
0029416850
-
The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man
-
Maggs L, Williams D, Pirmohamed M, Park B. The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man. J Pharmacol Exp Ther 1995: 275: 1463-75.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 1463-1475
-
-
Maggs, L.1
Williams, D.2
Pirmohamed, M.3
Park, B.4
-
39
-
-
0033938971
-
Induction of metabolism-dependent and -independent neutrophil apoptosis by clozapine
-
Williams DP, Pirmohamed M, Naisbitt DJ, Uetrecht JP, Park BK. Induction of metabolism-dependent and -independent neutrophil apoptosis by clozapine. Mol Pharmacol 2000: 58: 207-16.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 207-216
-
-
Williams, D.P.1
Pirmohamed, M.2
Naisbitt, D.J.3
Uetrecht, J.P.4
Park, B.K.5
-
40
-
-
0032410803
-
Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs
-
Naisbitt DJ, Williams DP, O'Nell PM et al. Metabolism-dependent neutrophil cytotoxicity of amodiaquine: a comparison with pyronaridine and related antimalarial drugs. Chem Res Toxicol 1998: 11: 1586-97.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 1586-1597
-
-
Naisbitt, D.J.1
Williams, D.P.2
O'Nell, P.M.3
-
41
-
-
0023204051
-
Quinoneimines as substrates for quinone reductase (NAD(P)H: (quinone-acceptor) oxidoreductase) and the effect of dicumarol on their cytotoxicity
-
Powis G, See KL, Santone KS, Melder DC, Hodnett EM. Quinoneimines as substrates for quinone reductase (NAD(P)H: (quinone-acceptor) oxidoreductase) and the effect of dicumarol on their cytotoxicity. Biochem Pharmacol 1987: 36: 2473-9.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 2473-2479
-
-
Powis, G.1
See, K.L.2
Santone, K.S.3
Melder, D.C.4
Hodnett, E.M.5
-
42
-
-
0344953575
-
Cytotoxicity and apoptosis of benzoquinones: Redox cycling, cytochrome c release, and BAD protein expression
-
Tudor G, Gutierrez P, Aguilera-Gutierrez A, Sausvill EA. Cytotoxicity and apoptosis of benzoquinones: redox cycling, cytochrome c release, and BAD protein expression. Biochem Pharmacol 2003: 65: 1061-75.
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 1061-1075
-
-
Tudor, G.1
Gutierrez, P.2
Aguilera-Gutierrez, A.3
Sausvill, E.A.4
-
43
-
-
0037058252
-
Predicting drug-induced agranulocytosis: Characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an vitro apoptosis assay for identifying drugs that may cause agranulocytosis
-
Iverson S, Zahid N, Uetrecht JP. Predicting drug-induced agranulocytosis: characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an vitro apoptosis assay for identifying drugs that may cause agranulocytosis. Chem Biol Interact 2002: 142: 175-99.
-
(2002)
Chem Biol Interact
, vol.142
, pp. 175-199
-
-
Iverson, S.1
Zahid, N.2
Uetrecht, J.P.3
|