-
2
-
-
33846970555
-
Metabolic syndrome: a multiplex cardiovascular risk factor
-
Grundy SM. Metabolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab 2007;92:399-404.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 399-404
-
-
Grundy, S.M.1
-
3
-
-
70350245011
-
Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
-
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009;120:1640-5.
-
(2009)
Circulation
, vol.120
, pp. 1640-1645
-
-
Alberti, K.G.1
Eckel, R.H.2
Grundy, S.M.3
Zimmet, P.Z.4
Cleeman, J.I.5
Donato, K.A.6
-
4
-
-
33344478392
-
Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls
-
Ye Z, Liu EH, Higgins JP, Keavney BD, Lowe GD, Collins R et al. Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66, 155 cases and 91, 307 controls. Lancet 2006;367:651-8.
-
(2006)
Lancet
, vol.367
, pp. 651-658
-
-
Ye, Z.1
Liu, E.H.2
Higgins, J.P.3
Keavney, B.D.4
Lowe, G.D.5
Collins, R.6
-
5
-
-
84859210770
-
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
-
IL6R Genetics Consortium Emerging Risk Factors Collaboration
-
IL6R Genetics Consortium Emerging Risk Factors Collaboration, Sarwar N, Butterworth AS, Freitag DF, Gregson J, Willeit P, Gorman DN et al. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 2012;379:1205-13.
-
(2012)
Lancet
, vol.379
, pp. 1205-1213
-
-
Sarwar, N.1
Butterworth, A.S.2
Freitag, D.F.3
Gregson, J.4
Willeit, P.5
Gorman, D.N.6
-
6
-
-
0024160877
-
Banting lecture 1988. Role of insulin resistance in human disease
-
Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37:1595-607.
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
7
-
-
0037463608
-
The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
-
Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB. The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch Intern Med 2003;163:427-36.
-
(2003)
Arch Intern Med
, vol.163
, pp. 427-436
-
-
Park, Y.W.1
Zhu, S.2
Palaniappan, L.3
Heshka, S.4
Carnethon, M.R.5
Heymsfield, S.B.6
-
8
-
-
1542510700
-
Acquired and inherited lipodystrophies
-
Garg A. Acquired and inherited lipodystrophies. N Engl J Med 2004;350:1220-34.
-
(2004)
N Engl J Med
, vol.350
, pp. 1220-1234
-
-
Garg, A.1
-
9
-
-
2542443652
-
Lipodystrophies: rare disorders causing metabolic syndrome
-
Garg A, Misra A. Lipodystrophies: rare disorders causing metabolic syndrome. Endocrinol Metab Clin North Am 2004;33:305-31.
-
(2004)
Endocrinol Metab Clin North Am
, vol.33
, pp. 305-331
-
-
Garg, A.1
Misra, A.2
-
10
-
-
36849071396
-
New metabolic phenotypes in laminopathies: LMNA mutations in patients with severe metabolic syndrome
-
Decaudain A, Vantyghem MC, Guerci B, Hécart AC, Auclair M, Reznik Y et al. New metabolic phenotypes in laminopathies: LMNA mutations in patients with severe metabolic syndrome. J Clin Endocrinol Metab 2007;92:4835-44.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 4835-4844
-
-
Decaudain, A.1
Vantyghem, M.C.2
Guerci, B.3
Hécart, A.C.4
Auclair, M.5
Reznik, Y.6
-
11
-
-
78650055830
-
Lipodystrophy: metabolic insights from a rare disorder
-
Huang-Doran I, Sleigh A, Rochford JJ, O'Rahilly S, Savage DB. Lipodystrophy: metabolic insights from a rare disorder. J Endocrinol 2010;207:245-55.
-
(2010)
J Endocrinol
, vol.207
, pp. 245-255
-
-
Huang-Doran, I.1
Sleigh, A.2
Rochford, J.J.3
O'Rahilly, S.4
Savage, D.B.5
-
12
-
-
70549098559
-
Mouse models of inherited lipodystrophy
-
Savage DB. Mouse models of inherited lipodystrophy. Dis Model Mech 2009;2:554-62.
-
(2009)
Dis Model Mech
, vol.2
, pp. 554-562
-
-
Savage, D.B.1
-
13
-
-
84907693957
-
Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications
-
Vernochet C, Damilano F, Mourier A, Bezy O, Mori MA, Smyth G et al. Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications. FASEB J 2014;28:4408-19.
-
(2014)
FASEB J
, vol.28
, pp. 4408-4419
-
-
Vernochet, C.1
Damilano, F.2
Mourier, A.3
Bezy, O.4
Mori, M.A.5
Smyth, G.6
-
14
-
-
34848872799
-
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
-
Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest 2007;117:2621-37.
-
(2007)
J Clin Invest
, vol.117
, pp. 2621-2637
-
-
Kim, J.Y.1
van de Wall, E.2
Laplante, M.3
Azzara, A.4
Trujillo, M.E.5
Hofmann, S.M.6
-
15
-
-
0015473277
-
Cellularity of adipose depots in six strains of genetically obese mice
-
Johnson PR, Hirsch J. Cellularity of adipose depots in six strains of genetically obese mice. J Lipid Res 1972;13:2-11.
-
(1972)
J Lipid Res
, vol.13
, pp. 2-11
-
-
Johnson, P.R.1
Hirsch, J.2
-
16
-
-
0015139897
-
Adipose tissue fat cell size and number in relation to metabolism in randomly selected middle-aged men and women
-
Björntorp P, Bengtsson C, Blohmé G, Jonsson A, Sjöström L, Tibblin E et al. Adipose tissue fat cell size and number in relation to metabolism in randomly selected middle-aged men and women. Metabolism 1971;20:927-35.
-
(1971)
Metabolism
, vol.20
, pp. 927-935
-
-
Björntorp, P.1
Bengtsson, C.2
Blohmé, G.3
Jonsson, A.4
Sjöström, L.5
Tibblin, E.6
-
17
-
-
39449092048
-
Hypertrophy and hyperplasia of abdominal adipose tissues in women
-
Drolet R, Richard C, Sniderman AD, Mailloux J, Fortier M, Huot C et al. Hypertrophy and hyperplasia of abdominal adipose tissues in women. Int J Obes (Lond) 2008;32:283-91.
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. 283-291
-
-
Drolet, R.1
Richard, C.2
Sniderman, A.D.3
Mailloux, J.4
Fortier, M.5
Huot, C.6
-
18
-
-
0015610779
-
Studies of human adipose tissue. Adipose cell size and number in nonobese and obese patients
-
Salans LB, Cushman SW, Weismann RE. Studies of human adipose tissue. Adipose cell size and number in nonobese and obese patients. J Clin Invest 1973;52:929-41.
-
(1973)
J Clin Invest
, vol.52
, pp. 929-941
-
-
Salans, L.B.1
Cushman, S.W.2
Weismann, R.E.3
-
19
-
-
0015972637
-
Body composition and adipose cellularity in human obesity
-
Sjostrom L, Björntorp P. Body composition and adipose cellularity in human obesity. Acta Med Scand 1974;195:201-11.
-
(1974)
Acta Med Scand
, vol.195
, pp. 201-211
-
-
Sjostrom, L.1
Björntorp, P.2
-
20
-
-
33846816368
-
Fat cell enlargement is an independent marker of insulin resistance and 'hyperleptinaemia'
-
Lundgren M, Svensson M, Lindmark S, Renstrom F, Ruge T, Eriksson JW. Fat cell enlargement is an independent marker of insulin resistance and 'hyperleptinaemia'. Diabetologia 2007;50:625-33.
-
(2007)
Diabetologia
, vol.50
, pp. 625-633
-
-
Lundgren, M.1
Svensson, M.2
Lindmark, S.3
Renstrom, F.4
Ruge, T.5
Eriksson, J.W.6
-
21
-
-
84862783589
-
The size of large adipose cells is a predictor of insulin resistance
-
Yang J, Eliasson B, Smith U, Cushman SW, Sherman AS. The size of large adipose cells is a predictor of insulin resistance. Obesity (Silver Spring) 2012;20:932-8.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 932-938
-
-
Yang, J.1
Eliasson, B.2
Smith, U.3
Cushman, S.W.4
Sherman, A.S.5
-
22
-
-
41049083146
-
Insulin resistance and body fat distribution in South Asian men compared to Caucasian men
-
Chandalia M, Lin P, Seenivasan T, Livingston EH, Snell PG, Grundy SM et al. Insulin resistance and body fat distribution in South Asian men compared to Caucasian men. PLoS ONE 2007;2:e812.
-
(2007)
PLoS ONE
, vol.2
-
-
Chandalia, M.1
Lin, P.2
Seenivasan, T.3
Livingston, E.H.4
Snell, P.G.5
Grundy, S.M.6
-
23
-
-
34447130417
-
Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis
-
McLaughlin T, Sherman A, Tsao P, Gonzalez O, Yee G, Lamendola C et al. Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis. Diabetologia 2007;50:1707-15.
-
(2007)
Diabetologia
, vol.50
, pp. 1707-1715
-
-
McLaughlin, T.1
Sherman, A.2
Tsao, P.3
Gonzalez, O.4
Yee, G.5
Lamendola, C.6
-
24
-
-
84895795817
-
Subcutaneous adipose cell size and distribution: relationship to insulin resistance and body fat
-
McLaughlin T, Lamendola C, Coghlan N, Liu TC, Lerner K, Sherman A et al. Subcutaneous adipose cell size and distribution: relationship to insulin resistance and body fat. Obesity (Silver Spring) 2014;22:673-80.
-
(2014)
Obesity (Silver Spring)
, vol.22
, pp. 673-680
-
-
McLaughlin, T.1
Lamendola, C.2
Coghlan, N.3
Liu, T.C.4
Lerner, K.5
Sherman, A.6
-
25
-
-
85006097026
-
Influence of upper and lower body adipose tissue on insulin sensitivity in South Asian men
-
Balakrishnan P, Grundy SM, Islam A, Dunn F, Vega GL. Influence of upper and lower body adipose tissue on insulin sensitivity in South Asian men. J Investig Med 2012;60:999-1004.
-
(2012)
J Investig Med
, vol.60
, pp. 999-1004
-
-
Balakrishnan, P.1
Grundy, S.M.2
Islam, A.3
Dunn, F.4
Vega, G.L.5
-
26
-
-
0023757258
-
Diabetes, hyperinsulinaemia, and coronary risk factors in Bangladeshis in east London
-
McKeigue PM, Marmot MG, Syndercombe Court YD, Cottier DE, Rahman S et al. Diabetes, hyperinsulinaemia, and coronary risk factors in Bangladeshis in east London. Br Heart J 1988;60:390-6.
-
(1988)
Br Heart J
, vol.60
, pp. 390-396
-
-
McKeigue, P.M.1
Marmot, M.G.2
Syndercombe Court, Y.D.3
Cottier, D.E.4
Rahman, S.5
-
27
-
-
0022406686
-
The Southall Diabetes Survey: prevalence of known diabetes in Asians and Europeans
-
Mather HM, Keen H. The Southall Diabetes Survey: prevalence of known diabetes in Asians and Europeans. Br Med J 1985;291:1081-4.
-
(1985)
Br Med J
, vol.291
, pp. 1081-1084
-
-
Mather, H.M.1
Keen, H.2
-
28
-
-
2942685611
-
Adipose tissue metabolites and insulin resistance in nondiabetic Asian Indian men
-
Abate N, Chandalia M, Snell PG, Grundy SM. Adipose tissue metabolites and insulin resistance in nondiabetic Asian Indian men. J Clin Endocrinol Metab 2004;89:2750-5.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2750-2755
-
-
Abate, N.1
Chandalia, M.2
Snell, P.G.3
Grundy, S.M.4
-
29
-
-
77956383646
-
Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis
-
Kursawe R, Eszlinger M, Narayan D, Liu T, Bazuine M, Cali AM et al. Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis. Diabetes 2010;59:2288-96.
-
(2010)
Diabetes
, vol.59
, pp. 2288-2296
-
-
Kursawe, R.1
Eszlinger, M.2
Narayan, D.3
Liu, T.4
Bazuine, M.5
Cali, A.M.6
-
30
-
-
0027998352
-
Estimation of adipose tissue mass by magnetic resonance imaging: validation against dissection in human cadavers
-
Abate N, Burns D, Peshock RM, Garg A, Grundy SM. Estimation of adipose tissue mass by magnetic resonance imaging: validation against dissection in human cadavers. J Lipid Res 1994;35:1490-6.
-
(1994)
J Lipid Res
, vol.35
, pp. 1490-1496
-
-
Abate, N.1
Burns, D.2
Peshock, R.M.3
Garg, A.4
Grundy, S.M.5
-
31
-
-
33751542483
-
Influence of body fat content and distribution on variation in metabolic risk
-
Vega GL, Adams-Huet B, Peshock R, Willett D, Shah B, Grundy SM. Influence of body fat content and distribution on variation in metabolic risk. J Clin Endocrinol Metab 2006;91:4459-66.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4459-4466
-
-
Vega, G.L.1
Adams-Huet, B.2
Peshock, R.3
Willett, D.4
Shah, B.5
Grundy, S.M.6
-
32
-
-
84878696500
-
Waist circumference as measure of abdominal fat compartments
-
Grundy SM, Neeland IJ, Turer AT, Vega GL. Waist circumference as measure of abdominal fat compartments. J Obes 2013;2013:454285.
-
(2013)
J Obes
, vol.2013
-
-
Grundy, S.M.1
Neeland, I.J.2
Turer, A.T.3
Vega, G.L.4
-
33
-
-
0025748673
-
Metabolic implications of body fat distribution
-
Bjorntorp P. Metabolic implications of body fat distribution. Diabetes Care 1991;14:1132-43.
-
(1991)
Diabetes Care
, vol.14
, pp. 1132-1143
-
-
Bjorntorp, P.1
-
34
-
-
0028091785
-
Regional adiposity and morbidity
-
Kissebah AH, Krakower GR. Regional adiposity and morbidity. Physiol Rev 1994;74:761-811.
-
(1994)
Physiol Rev
, vol.74
, pp. 761-811
-
-
Kissebah, A.H.1
Krakower, G.R.2
-
35
-
-
55849106577
-
Role of body fat distribution and the metabolic complications of obesity
-
Jensen MD. Role of body fat distribution and the metabolic complications of obesity. J Clin Endocrinol Metab 2008;93(11 Suppl 1):S57-63.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.11
, pp. S57-S63
-
-
Jensen, M.D.1
-
36
-
-
33644822875
-
Visceral obesity: a "civilization syndrome"
-
Björntorp P. Visceral obesity: a "civilization syndrome". Obes Res 1993;1:206-22.
-
(1993)
Obes Res
, vol.1
, pp. 206-222
-
-
Björntorp, P.1
-
37
-
-
0029049528
-
Contribution of visceral fat mass to the insulin resistance of aging
-
Cefalu WT, Wang ZQ, Webel S, Bell-Farrow A, Crouse JR, Hinson WH. Contribution of visceral fat mass to the insulin resistance of aging. Metabolism 1995;44:954-9.
-
(1995)
Metabolism
, vol.44
, pp. 954-959
-
-
Cefalu, W.T.1
Wang, Z.Q.2
Webel, S.3
Bell-Farrow, A.4
Crouse, J.R.5
Hinson, W.H.6
-
38
-
-
0025083282
-
Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels
-
Seidell JC, Bjorntorp P, Sjostrom L, Kvist H, Sannerstedt R. Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels. Metabolism 1990;39:897-901.
-
(1990)
Metabolism
, vol.39
, pp. 897-901
-
-
Seidell, J.C.1
Bjorntorp, P.2
Sjostrom, L.3
Kvist, H.4
Sannerstedt, R.5
-
39
-
-
33646946281
-
Visceral fat is an independent predictor of all-cause mortality in men
-
Kuk JL, Katzmarzyk PT, Nichaman MZ, Church TS, Blair SN, Ross R. Visceral fat is an independent predictor of all-cause mortality in men. Obesity 2006;14:336-42.
-
(2006)
Obesity
, vol.14
, pp. 336-342
-
-
Kuk, J.L.1
Katzmarzyk, P.T.2
Nichaman, M.Z.3
Church, T.S.4
Blair, S.N.5
Ross, R.6
-
40
-
-
80052070656
-
The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism
-
Matsuzawa Y, Funahashi T, Nakamura T. The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism. J Atheroscler Thromb 2011;18:629-39.
-
(2011)
J Atheroscler Thromb
, vol.18
, pp. 629-639
-
-
Matsuzawa, Y.1
Funahashi, T.2
Nakamura, T.3
-
41
-
-
84872327440
-
Pathophysiology of human visceral obesity: an update
-
Tchernof A, Després JP. Pathophysiology of human visceral obesity: an update. Physiol Rev 2013;93:359-404.
-
(2013)
Physiol Rev
, vol.93
, pp. 359-404
-
-
Tchernof, A.1
Després, J.P.2
-
42
-
-
0029087640
-
Relationships of generalized and regional adiposity to insulin sensitivity in men
-
Abate N, Garg A, Peshock RM, Stray-Gundersen J, Grundy SM. Relationships of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest 1995;96:88-98.
-
(1995)
J Clin Invest
, vol.96
, pp. 88-98
-
-
Abate, N.1
Garg, A.2
Peshock, R.M.3
Stray-Gundersen, J.4
Grundy, S.M.5
-
43
-
-
0030765908
-
Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat
-
Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE. Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 1997;46:1579-85.
-
(1997)
Diabetes
, vol.46
, pp. 1579-1585
-
-
Goodpaster, B.H.1
Thaete, F.L.2
Simoneau, J.A.3
Kelley, D.E.4
-
44
-
-
0034129495
-
Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance
-
Kelley DE, Thaete FL, Troost F, Huwe T, Goodpaster BH. Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance. Am J Physiol 2000;278:E941-8.
-
(2000)
Am J Physiol
, vol.278
, pp. E941-E948
-
-
Kelley, D.E.1
Thaete, F.L.2
Troost, F.3
Huwe, T.4
Goodpaster, B.H.5
-
45
-
-
0033985314
-
Relation of regional fat distribution to insulin sensitivity in postmenopausal women
-
Sites CK, Calles-Escandon J, Brochu M, Butterfield M, Ashikaga T, Poehlman ET. Relation of regional fat distribution to insulin sensitivity in postmenopausal women. Fertil Steril 2000;73:61-5.
-
(2000)
Fertil Steril
, vol.73
, pp. 61-65
-
-
Sites, C.K.1
Calles-Escandon, J.2
Brochu, M.3
Butterfield, M.4
Ashikaga, T.5
Poehlman, E.T.6
-
46
-
-
0035090380
-
Relationship between abdominal fat compartments and glucose and lipid metabolism in early postmenopausal women
-
Rendell M, Hulthen UL, Tornquist C, Groop L, Mattiasson I. Relationship between abdominal fat compartments and glucose and lipid metabolism in early postmenopausal women. J Clin Endocrinol Metab 2001;86:744-9.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 744-749
-
-
Rendell, M.1
Hulthen, U.L.2
Tornquist, C.3
Groop, L.4
Mattiasson, I.5
-
47
-
-
0024244339
-
Measurement of plasma glucose, free fatty acid, lactate and insulin for 24 h in patients with NIDDM
-
Reaven GM, Hollenbeck C, Jeng C-Y, Wu MS, Chen YD. Measurement of plasma glucose, free fatty acid, lactate and insulin for 24 h in patients with NIDDM. Diabetes 1988;37:1020-4.
-
(1988)
Diabetes
, vol.37
, pp. 1020-1024
-
-
Reaven, G.M.1
Hollenbeck, C.2
Jeng, C.-Y.3
Wu, M.S.4
Chen, Y.D.5
-
48
-
-
0022531052
-
Effect of obesity on ambient plasma glucose, free fatty acid, insulin, growth hormone, and glucagon concentrations
-
Golay A, Swislocki AL, Chen YD, Jaspan JB, Reaven GM. Effect of obesity on ambient plasma glucose, free fatty acid, insulin, growth hormone, and glucagon concentrations. J Clin Endocrinol Metab 1986;63:481-4.
-
(1986)
J Clin Endocrinol Metab
, vol.63
, pp. 481-484
-
-
Golay, A.1
Swislocki, A.L.2
Chen, Y.D.3
Jaspan, J.B.4
Reaven, G.M.5
-
49
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997;46:3-10.
-
(1997)
Diabetes
, vol.46
, pp. 3-10
-
-
Boden, G.1
-
50
-
-
0035143139
-
Temporal patterns of circulating leptin levels in lean and obese adolescents: relationships to insulin, growth hormone, and free fatty acids rhythmicity
-
Heptulla R, Smitten A, Teague B, Tamborlane WV, Ma Y-Z, Caprio S. Temporal patterns of circulating leptin levels in lean and obese adolescents: relationships to insulin, growth hormone, and free fatty acids rhythmicity. J Clin Endocrinol Metab 2001;86:90-6.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 90-96
-
-
Heptulla, R.1
Smitten, A.2
Teague, B.3
Tamborlane, W.V.4
Ma, Y.-Z.5
Caprio, S.6
-
51
-
-
50449086746
-
Obesity and free fatty acids (FFA)
-
Boden G. Obesity and free fatty acids (FFA). Endocrinol Metab Clin North Am 2008;37:635-46.
-
(2008)
Endocrinol Metab Clin North Am
, vol.37
, pp. 635-646
-
-
Boden, G.1
-
52
-
-
0029921856
-
Are increased plasma non-esterified fatty acid concentrations a risk marker for coronary heart disease and other chronic diseases?
-
Frayn KN, Williams CM, Arner P. Are increased plasma non-esterified fatty acid concentrations a risk marker for coronary heart disease and other chronic diseases? Clin Sci (Lond) 1996;90:243-53.
-
(1996)
Clin Sci (Lond)
, vol.90
, pp. 243-253
-
-
Frayn, K.N.1
Williams, C.M.2
Arner, P.3
-
53
-
-
0002031490
-
Insulin resistance, lipid and fatty acid concentrations in 867 healthy Europeans. European Group for the Study of Insulin Resistance (EGIR)
-
Baldeweg SE, Golay A, Natali A, Balkau B, Del Prato S, Coppack SW. Insulin resistance, lipid and fatty acid concentrations in 867 healthy Europeans. European Group for the Study of Insulin Resistance (EGIR). Eur J Clin Invest 2000;30:45-52.
-
(2000)
Eur J Clin Invest
, vol.30
, pp. 45-52
-
-
Baldeweg, S.E.1
Golay, A.2
Natali, A.3
Balkau, B.4
Del Prato, S.5
Coppack, S.W.6
-
54
-
-
48149097201
-
Adipose tissue fatty acid metabolism in insulin-resistant men
-
Bickerton AS, Roberts R, Fielding BA, Tornqvist H, Blaak EE, Wagenmakers AJ. Adipose tissue fatty acid metabolism in insulin-resistant men. Diabetologia 2008;51:1466-74.
-
(2008)
Diabetologia
, vol.51
, pp. 1466-1474
-
-
Bickerton, A.S.1
Roberts, R.2
Fielding, B.A.3
Tornqvist, H.4
Blaak, E.E.5
Wagenmakers, A.J.6
-
55
-
-
0024602053
-
Influence of body fat distribution on free fatty acid metabolism in obesity
-
Jensen MD, Haymond MW, Rizza RA, Cryer PE, Miles JM. Influence of body fat distribution on free fatty acid metabolism in obesity. J Clin Invest 1989;83:1168-73.
-
(1989)
J Clin Invest
, vol.83
, pp. 1168-1173
-
-
Jensen, M.D.1
Haymond, M.W.2
Rizza, R.A.3
Cryer, P.E.4
Miles, J.M.5
-
56
-
-
0032793212
-
Regional postprandial fatty acid metabolism in different obesity phenotypes
-
Guo ZK, Hensrud DD, Johnson CM, Jensen MD. Regional postprandial fatty acid metabolism in different obesity phenotypes. Diabetes 1999;48:1586-92.
-
(1999)
Diabetes
, vol.48
, pp. 1586-1592
-
-
Guo, Z.K.1
Hensrud, D.D.2
Johnson, C.M.3
Jensen, M.D.4
-
57
-
-
85047690933
-
Splanchnic lipolysis in human obesity
-
Nielsen S, Guo ZK, Johnson CM, Hensrud DD, Jensen MD. Splanchnic lipolysis in human obesity. J Clin Invest 2004;113:1582-8.
-
(2004)
J Clin Invest
, vol.113
, pp. 1582-1588
-
-
Nielsen, S.1
Guo, Z.K.2
Johnson, C.M.3
Hensrud, D.D.4
Jensen, M.D.5
-
58
-
-
0027444656
-
Postprandial free fatty acid kinetics are abnormal in upper body obesity
-
Roust LR, Jensen MD. Postprandial free fatty acid kinetics are abnormal in upper body obesity. Diabetes 1993;42:1567-73.
-
(1993)
Diabetes
, vol.42
, pp. 1567-1573
-
-
Roust, L.R.1
Jensen, M.D.2
-
60
-
-
63349086412
-
Ethnic differences in hepatic steatosis: an insulin resistance paradox?
-
Guerrero R, Vega GL, Grundy SM, Browning JD. Ethnic differences in hepatic steatosis: an insulin resistance paradox? Hepatology 2009;49:791-801.
-
(2009)
Hepatology
, vol.49
, pp. 791-801
-
-
Guerrero, R.1
Vega, G.L.2
Grundy, S.M.3
Browning, J.D.4
-
61
-
-
84866598896
-
Ethnic influences on the relations between abdominal subcutaneous and visceral adiposity, liver fat, and cardiometabolic risk profile: the International Study of Prediction of Intra-Abdominal Adiposity and Its Relationship with Cardiometabolic Risk/Intra-Abdominal Adiposity
-
Nazare JA, Smith JD, Borel AL, Haffner SM, Balkau B, Ross R et al. Ethnic influences on the relations between abdominal subcutaneous and visceral adiposity, liver fat, and cardiometabolic risk profile: the International Study of Prediction of Intra-Abdominal Adiposity and Its Relationship with Cardiometabolic Risk/Intra-Abdominal Adiposity. Am J Clin Nutr 2012;96:714-26.
-
(2012)
Am J Clin Nutr
, vol.96
, pp. 714-726
-
-
Nazare, J.A.1
Smith, J.D.2
Borel, A.L.3
Haffner, S.M.4
Balkau, B.5
Ross, R.6
-
62
-
-
84931098539
-
Clinical significance of visceral adiposity assessed by computed tomography: a Japanese perspective
-
Ryo M, Kishida K, Nakamura T, Yoshizumi T, Funahashi T, Shimomura I. Clinical significance of visceral adiposity assessed by computed tomography: a Japanese perspective. World J Radiol 2014;6:409-16.
-
(2014)
World J Radiol
, vol.6
, pp. 409-416
-
-
Ryo, M.1
Kishida, K.2
Nakamura, T.3
Yoshizumi, T.4
Funahashi, T.5
Shimomura, I.6
-
63
-
-
84923091378
-
Biology of upper-body and lower-body adipose tissue-link to whole-body phenotypes
-
Karpe F, Pinnick KE. Biology of upper-body and lower-body adipose tissue-link to whole-body phenotypes. Nat Rev Endocrinol 2015;11:90-100.
-
(2015)
Nat Rev Endocrinol
, vol.11
, pp. 90-100
-
-
Karpe, F.1
Pinnick, K.E.2
-
64
-
-
0025778917
-
Contribution of regional adipose tissue depots to plasma lipoprotein concentrations in overweight men and women: possible protective effects of thigh fat
-
Terry RB, Stefanick ML, Haskell WL, Wood PD. Contribution of regional adipose tissue depots to plasma lipoprotein concentrations in overweight men and women: possible protective effects of thigh fat. Metabolism 1991;40:733-40.
-
(1991)
Metabolism
, vol.40
, pp. 733-740
-
-
Terry, R.B.1
Stefanick, M.L.2
Haskell, W.L.3
Wood, P.D.4
-
65
-
-
0029194133
-
Body compartment and subcutaneous adipose tissue distribution-risk factor patterns in obese subjects
-
Sjostrom CD, Hakangard AC, Lissner L, Sjostrom L. Body compartment and subcutaneous adipose tissue distribution-risk factor patterns in obese subjects. Obes Res 1995;3:9-22.
-
(1995)
Obes Res
, vol.3
, pp. 9-22
-
-
Sjostrom, C.D.1
Hakangard, A.C.2
Lissner, L.3
Sjostrom, L.4
-
66
-
-
0034878336
-
Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study
-
Seidell JC, Perusse L, Despres J-P, Bouchard C. Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study. Am J Clin Nutr 2001;74:315-21.
-
(2001)
Am J Clin Nutr
, vol.74
, pp. 315-321
-
-
Seidell, J.C.1
Perusse, L.2
Despres, J.-P.3
Bouchard, C.4
-
67
-
-
0037382301
-
Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women
-
Tankó LB, Bagger YZ, Alexandersen P, Christiansen C. Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women. Circulation 2003;107:1626-31.
-
(2003)
Circulation
, vol.107
, pp. 1626-1631
-
-
Tankó, L.B.1
Bagger, Y.Z.2
Alexandersen, P.3
Christiansen, C.4
-
68
-
-
84867577535
-
Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo
-
Manolopoulos KN, Karpe F, Frayn KN. Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo. Diabetologia 2012;55:3029-37.
-
(2012)
Diabetologia
, vol.55
, pp. 3029-3037
-
-
Manolopoulos, K.N.1
Karpe, F.2
Frayn, K.N.3
-
69
-
-
84908635308
-
Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications
-
Pinnick KE, Nicholson G, Manolopoulos KN, McQuaid SE, Valet P, Frayn KN et al. Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications. Diabetes 2014;63:3785-97.
-
(2014)
Diabetes
, vol.63
, pp. 3785-3797
-
-
Pinnick, K.E.1
Nicholson, G.2
Manolopoulos, K.N.3
McQuaid, S.E.4
Valet, P.5
Frayn, K.N.6
-
70
-
-
84929001601
-
Abdominal obesity: a marker of ectopic fat accumulation
-
Smith U. Abdominal obesity: a marker of ectopic fat accumulation. J Clin Invest 2015;125:1790-2.
-
(2015)
J Clin Invest
, vol.125
, pp. 1790-1792
-
-
Smith, U.1
-
71
-
-
84885579074
-
Altered subcutaneous abdominal adipose tissue lipid synthesis in obese, insulin-resistant humans
-
Tuvdendorj D, Chandalia M, Batbayar T, Saraf M, Beysen C, Murphy EJ et al. Altered subcutaneous abdominal adipose tissue lipid synthesis in obese, insulin-resistant humans. Am J Physiol Endocrinol Metab 2013;305:E999-1006.
-
(2013)
Am J Physiol Endocrinol Metab
, vol.305
, pp. E999-1006
-
-
Tuvdendorj, D.1
Chandalia, M.2
Batbayar, T.3
Saraf, M.4
Beysen, C.5
Murphy, E.J.6
-
72
-
-
34248146026
-
Direct free fatty acid uptake into human adipocytes in vivo: relation to body fat distribution
-
Shadid S, Koutsari C, Jensen MD. Direct free fatty acid uptake into human adipocytes in vivo: relation to body fat distribution. Diabetes 2007;56:1369-75.
-
(2007)
Diabetes
, vol.56
, pp. 1369-1375
-
-
Shadid, S.1
Koutsari, C.2
Jensen, M.D.3
-
73
-
-
80053408094
-
Fatty acids, obesity, and insulin resistance: time for a reevaluation
-
Karpe F, Dickmann JR, Frayn KN. Fatty acids, obesity, and insulin resistance: time for a reevaluation. Diabetes 2011;60:2441-9.
-
(2011)
Diabetes
, vol.60
, pp. 2441-2449
-
-
Karpe, F.1
Dickmann, J.R.2
Frayn, K.N.3
-
74
-
-
36849086911
-
Splanchnic spillover of extracellular lipase-generated fatty acids in overweight and obese humans
-
Nelson RH, Basu R, Johnson CM, Rizza RA, Miles JM. Splanchnic spillover of extracellular lipase-generated fatty acids in overweight and obese humans. Diabetes 2007;56:2878-84.
-
(2007)
Diabetes
, vol.56
, pp. 2878-2884
-
-
Nelson, R.H.1
Basu, R.2
Johnson, C.M.3
Rizza, R.A.4
Miles, J.M.5
-
75
-
-
84901944641
-
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
-
Perry RJ, Samuel VT, Petersen KF, Shulman GI. The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. Nature 2014;510:84-91.
-
(2014)
Nature
, vol.510
, pp. 84-91
-
-
Perry, R.J.1
Samuel, V.T.2
Petersen, K.F.3
Shulman, G.I.4
-
76
-
-
0019226395
-
Studies of very low density lipoprotein triglyceride metabolism in an obese population with low plasma lipids: lack of influence of body weight or plasma insulin
-
Howard BV, Zech L, Davis M, Bennion LJ, Savage PJ, Nagulesparan M et al. Studies of very low density lipoprotein triglyceride metabolism in an obese population with low plasma lipids: lack of influence of body weight or plasma insulin. J Lipid Res 1980;21:1032-41.
-
(1980)
J Lipid Res
, vol.21
, pp. 1032-1041
-
-
Howard, B.V.1
Zech, L.2
Davis, M.3
Bennion, L.J.4
Savage, P.J.5
Nagulesparan, M.6
-
77
-
-
0018364379
-
Transport of very low density lipoprotein triglycerides in varying degrees of obesity and hypertriglyceridemia
-
Grundy SM, Mok HY, Zech L, Steinberg D, Berman M. Transport of very low density lipoprotein triglycerides in varying degrees of obesity and hypertriglyceridemia. J Clin Invest 1979;63:1274-83.
-
(1979)
J Clin Invest
, vol.63
, pp. 1274-1283
-
-
Grundy, S.M.1
Mok, H.Y.2
Zech, L.3
Steinberg, D.4
Berman, M.5
-
78
-
-
0023811760
-
Obesity and insulin resistance: lessons learned from the Pima Indians
-
Lillioja S, Bogardus C. Obesity and insulin resistance: lessons learned from the Pima Indians. Diabetes Metab Rev 1988;4:517-40.
-
(1988)
Diabetes Metab Rev
, vol.4
, pp. 517-540
-
-
Lillioja, S.1
Bogardus, C.2
-
79
-
-
0042324117
-
Do measures of body fat distribution provide information on the risk of type 2 diabetes in addition to measures of general obesity? Comparison of anthropometric predictors of type 2 diabetes in Pima Indians
-
Tulloch-Reid MK, Williams DE, Looker HC, Hanson RL, Knowler WC. Do measures of body fat distribution provide information on the risk of type 2 diabetes in addition to measures of general obesity? Comparison of anthropometric predictors of type 2 diabetes in Pima Indians. Diabetes Care 2003;26:2556-61.
-
(2003)
Diabetes Care
, vol.26
, pp. 2556-2561
-
-
Tulloch-Reid, M.K.1
Williams, D.E.2
Looker, H.C.3
Hanson, R.L.4
Knowler, W.C.5
-
80
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005;115:1343-51.
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
81
-
-
24144470430
-
Spillover of dietary fatty acids and use of serum nonesterified fatty acids for the synthesis of VLDL-triacylglycerol under two different feeding regimens
-
Barrows BR, Timlin MT, Parks EJ. Spillover of dietary fatty acids and use of serum nonesterified fatty acids for the synthesis of VLDL-triacylglycerol under two different feeding regimens. Diabetes 2005;54:2668-73.
-
(2005)
Diabetes
, vol.54
, pp. 2668-2673
-
-
Barrows, B.R.1
Timlin, M.T.2
Parks, E.J.3
-
82
-
-
84878223958
-
Spillover of fatty acids during dietary fat storage in type 2 diabetes: relationship to body fat depots and effects of weight loss
-
Almandoz JP, Singh E, Howell LA, Grothe K, Vlazny DT, Smailovic A et al. Spillover of fatty acids during dietary fat storage in type 2 diabetes: relationship to body fat depots and effects of weight loss. Diabetes 2013;62:1897-903.
-
(2013)
Diabetes
, vol.62
, pp. 1897-1903
-
-
Almandoz, J.P.1
Singh, E.2
Howell, L.A.3
Grothe, K.4
Vlazny, D.T.5
Smailovic, A.6
-
83
-
-
78751534190
-
Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?
-
McQuaid SE, Hodson L, Neville MJ, Dennis AL, Cheeseman J, Humphreys SM. Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition? Diabetes 2011;60:47-55.
-
(2011)
Diabetes
, vol.60
, pp. 47-55
-
-
McQuaid, S.E.1
Hodson, L.2
Neville, M.J.3
Dennis, A.L.4
Cheeseman, J.5
Humphreys, S.M.6
-
84
-
-
0037216466
-
Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets
-
Schwarz JM, Linfoot P, Dare D, Aghajanian K. Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets. Am J Clin Nutr 2003;77:43-50.
-
(2003)
Am J Clin Nutr
, vol.77
, pp. 43-50
-
-
Schwarz, J.M.1
Linfoot, P.2
Dare, D.3
Aghajanian, K.4
-
85
-
-
84914661984
-
Carbohydrate-induced and fat-induced lipemia
-
Ahrens EH Jr, Hirsch J, Oette K, Farquhar JW, Stein Y. Carbohydrate-induced and fat-induced lipemia. Trans Assoc Am Physicians 1961;74:134-46.
-
(1961)
Trans Assoc Am Physicians
, vol.74
, pp. 134-146
-
-
Ahrens, E.H.1
Hirsch, J.2
Oette, K.3
Farquhar, J.W.4
Stein, Y.5
-
86
-
-
0022559947
-
Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol
-
Grundy SM. Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol. N Engl J Med 1986;314:745-8.
-
(1986)
N Engl J Med
, vol.314
, pp. 745-748
-
-
Grundy, S.M.1
-
87
-
-
0026661119
-
Comparison of effects of high and low carbohydrate diets on plasma lipoproteins and insulin sensitivity in patients with mild NIDDM
-
Garg A, Grundy SM, Unger RH. Comparison of effects of high and low carbohydrate diets on plasma lipoproteins and insulin sensitivity in patients with mild NIDDM. Diabetes 1992;41:1278-85.
-
(1992)
Diabetes
, vol.41
, pp. 1278-1285
-
-
Garg, A.1
Grundy, S.M.2
Unger, R.H.3
-
88
-
-
84858964200
-
Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders
-
Lehr S, Hartwig S, Sell H. Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders. Proteomics Clin Appl 2012;6:91-101.
-
(2012)
Proteomics Clin Appl
, vol.6
, pp. 91-101
-
-
Lehr, S.1
Hartwig, S.2
Sell, H.3
-
89
-
-
19044393872
-
Adipose tissue, inflammation, and cardiovascular disease
-
Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ Res 2005;96:939-49.
-
(2005)
Circ Res
, vol.96
, pp. 939-949
-
-
Berg, A.H.1
Scherer, P.E.2
-
90
-
-
84924014641
-
20 years of leptin: from the discovery of the leptin gene to leptin in our therapeutic armamentarium
-
Friedman JM, Mantzoros CS. 20 years of leptin: from the discovery of the leptin gene to leptin in our therapeutic armamentarium. Metabolism 2015;64:1-4.
-
(2015)
Metabolism
, vol.64
, pp. 1-4
-
-
Friedman, J.M.1
Mantzoros, C.S.2
-
91
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montaque CT, Farooqi S, Whitehead JP, Soos MA, Rau H, Wareham NJ et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997;387:903-8.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montaque, C.T.1
Farooqi, S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
-
92
-
-
0344450708
-
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
-
Clement K, Vaisse C, Lahlou N, Cabrol S, Pelloux V, Cassuto D et al. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998;392:398-401.
-
(1998)
Nature
, vol.392
, pp. 398-401
-
-
Clement, K.1
Vaisse, C.2
Lahlou, N.3
Cabrol, S.4
Pelloux, V.5
Cassuto, D.6
-
93
-
-
0028845877
-
Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995;1:1155-61.
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
-
94
-
-
0032065645
-
Clinical review 94: what's in a name? In search of leptin'sphysiologic role
-
Flier JS. Clinical review 94: what's in a name? In search of leptin'sphysiologic role. J Clin Endocrinol Metab 1998;83:1407-13.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 1407-1413
-
-
Flier, J.S.1
-
95
-
-
0037148928
-
Leptin-replacement therapy for lipodystrophy
-
Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P et al. Leptin-replacement therapy for lipodystrophy. N Engl J Med 2002;346:570-8.
-
(2002)
N Engl J Med
, vol.346
, pp. 570-578
-
-
Oral, E.A.1
Simha, V.2
Ruiz, E.3
Andewelt, A.4
Premkumar, A.5
Snell, P.6
-
96
-
-
84891829091
-
Serum leptin and total dietary energy intake: the INTERLIPID Study
-
Nakamura Y, Ueshima H, Okuda N, Murakami Y, Miura K, Kita Y et al. Serum leptin and total dietary energy intake: the INTERLIPID Study. Eur J Nutr 2013;52:1641-8.
-
(2013)
Eur J Nutr
, vol.52
, pp. 1641-1648
-
-
Nakamura, Y.1
Ueshima, H.2
Okuda, N.3
Murakami, Y.4
Miura, K.5
Kita, Y.6
-
97
-
-
84907195705
-
20 years of leptin: leptin in common obesity and associated disorders of metabolism
-
DePaoli AM. 20 years of leptin: leptin in common obesity and associated disorders of metabolism. J Endocrinol 2014;223:T71-81.
-
(2014)
J Endocrinol
, vol.223
, pp. T71-T81
-
-
DePaoli, A.M.1
-
98
-
-
0041519355
-
Adiponectin: systemic contributor to insulin sensitivity
-
Pajvani UB, Scherer PE. Adiponectin: systemic contributor to insulin sensitivity. Curr Diab Rep 2003;3:207-13.
-
(2003)
Curr Diab Rep
, vol.3
, pp. 207-213
-
-
Pajvani, U.B.1
Scherer, P.E.2
-
99
-
-
84898429055
-
A novel ADIPOQ mutation (p. M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome
-
Bueno AC, Sun K, Martins CS, Elias J Jr, Miranda W, Tao C et al. A novel ADIPOQ mutation (p. M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome. J Clin Endocrinol Metab 2014;99:E683-93.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. E683-E693
-
-
Bueno, A.C.1
Sun, K.2
Martins, C.S.3
Elias, J.4
Miranda, W.5
Tao, C.6
-
100
-
-
84889633355
-
Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans
-
Sandy An S, Palmer ND, Hanley AJ, Ziegler JT, Mark Brown W, Freedman BI et al. Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans. Obesity (Silver Spring) 2013;21:E721-9.
-
(2013)
Obesity (Silver Spring)
, vol.21
, pp. E721-E729
-
-
Sandy An, S.1
Palmer, N.D.2
Hanley, A.J.3
Ziegler, J.T.4
Mark Brown, W.5
Freedman, B.I.6
-
101
-
-
84901770528
-
Association of the ADIPOQ T45G polymorphism with insulin resistance and blood glucose: a meta-analysis
-
Cao D, Ouyang S, Liu Z, Ma F, Wu J. Association of the ADIPOQ T45G polymorphism with insulin resistance and blood glucose: a meta-analysis. Endocr J 2014;61:437-46.
-
(2014)
Endocr J
, vol.61
, pp. 437-446
-
-
Cao, D.1
Ouyang, S.2
Liu, Z.3
Ma, F.4
Wu, J.5
-
102
-
-
27444443876
-
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
-
Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, American Heart Association, National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005;112:2735-52.
-
(2005)
Circulation
, vol.112
, pp. 2735-2752
-
-
Grundy, S.M.1
Cleeman, J.I.2
Daniels, S.R.3
Donato, K.A.4
Eckel, R.H.5
Franklin, B.A.6
-
103
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796-808.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
104
-
-
84860441011
-
Inflammation and lipid signaling in the etiology of insulin resistance
-
Glass CK, Olefsky JM. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab 2012;15:635-45.
-
(2012)
Cell Metab
, vol.15
, pp. 635-645
-
-
Glass, C.K.1
Olefsky, J.M.2
-
105
-
-
34247363281
-
Metabolic syndrome phenotype in very obese women
-
Chang C, Garcia-Garcia AB, Hamilton E, Shah B, Meguro S, Grundy SM et al. Metabolic syndrome phenotype in very obese women. Metab Syndr Relat Disord 2007;5:3-12.
-
(2007)
Metab Syndr Relat Disord
, vol.5
, pp. 3-12
-
-
Chang, C.1
Garcia-Garcia, A.B.2
Hamilton, E.3
Shah, B.4
Meguro, S.5
Grundy, S.M.6
-
106
-
-
69949100983
-
Sex differences in the relationship between C-reactive protein and body fat
-
Khera A, Vega GL, Das SR, Ayers C, McGuire DK, Grundy SM et al. Sex differences in the relationship between C-reactive protein and body fat. J Clin Endocrinol Metab 2009;94:3251-8.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 3251-3258
-
-
Khera, A.1
Vega, G.L.2
Das, S.R.3
Ayers, C.4
McGuire, D.K.5
Grundy, S.M.6
-
107
-
-
84884905521
-
Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults
-
Neeland IJ, Ayers CR, Rohatgi AK, Turer AT, Berry JD, Das SR et al. Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults. Obesity (Silver Spring) 2013;21:E439-47.
-
(2013)
Obesity (Silver Spring)
, vol.21
, pp. E439-E447
-
-
Neeland, I.J.1
Ayers, C.R.2
Rohatgi, A.K.3
Turer, A.T.4
Berry, J.D.5
Das, S.R.6
-
108
-
-
0034704893
-
C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
-
Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000;342:836-43.
-
(2000)
N Engl J Med
, vol.342
, pp. 836-843
-
-
Ridker, P.M.1
Hennekens, C.H.2
Buring, J.E.3
Rifai, N.4
-
109
-
-
0035908632
-
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
-
Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001;286:327-34.
-
(2001)
JAMA
, vol.286
, pp. 327-334
-
-
Pradhan, A.D.1
Manson, J.E.2
Rifai, N.3
Buring, J.E.4
Ridker, P.M.5
-
110
-
-
2942670689
-
Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
-
Review.
-
Ridker PM, Wilson PW, Grundy SM. Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation 2004;109:2818-25. Review.
-
(2004)
Circulation
, vol.109
, pp. 2818-2825
-
-
Ridker, P.M.1
Wilson, P.W.2
Grundy, S.M.3
-
111
-
-
84880918511
-
Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis
-
Everett BM, Pradhan AD, Solomon DH, Paynter N, Macfadyen J, Zaharris E et al. Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis. Am Heart J 2013;166:199-207.
-
(2013)
Am Heart J
, vol.166
, pp. 199-207
-
-
Everett, B.M.1
Pradhan, A.D.2
Solomon, D.H.3
Paynter, N.4
Macfadyen, J.5
Zaharris, E.6
-
112
-
-
0030975615
-
Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease
-
Alessi MC, Peiretti F, Morange P, Henry M, Nalbone G, Juhan-Vague I. Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease. Diabetes 1997;46:860-7.
-
(1997)
Diabetes
, vol.46
, pp. 860-867
-
-
Alessi, M.C.1
Peiretti, F.2
Morange, P.3
Henry, M.4
Nalbone, G.5
Juhan-Vague, I.6
-
113
-
-
0035195629
-
Subcutaneous abdominal, but not femoral fat expression of plasminogen activator inhibitor-1 (PAI-1) is related to plasma PAI-1 levels and insulin resistance and decreases after weight loss
-
Mavri A, Alessi MC, Bastelica D, Geel-Georgelin O, Fina F, Sentocnik JT et al. Subcutaneous abdominal, but not femoral fat expression of plasminogen activator inhibitor-1 (PAI-1) is related to plasma PAI-1 levels and insulin resistance and decreases after weight loss. Diabetologia 2001;44:2025-31.
-
(2001)
Diabetologia
, vol.44
, pp. 2025-2031
-
-
Mavri, A.1
Alessi, M.C.2
Bastelica, D.3
Geel-Georgelin, O.4
Fina, F.5
Sentocnik, J.T.6
-
114
-
-
0029805074
-
Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris
-
Juhan-Vague I, Pyke SDM, Alessi MC, Jespersen J, Haverkate F, Thompson SG. Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. Circulation 1996;94:2057-63.
-
(1996)
Circulation
, vol.94
, pp. 2057-2063
-
-
Juhan-Vague, I.1
Pyke, S.D.M.2
Alessi, M.C.3
Jespersen, J.4
Haverkate, F.5
Thompson, S.G.6
-
115
-
-
0032564442
-
High plasminogen activator inhibitor and tissue plasminogen activator levels in plasma precede a first acute myocardial infraction in both men and women: evidence for the fibrinolytic system as an independent primary risk factor
-
Thogersen AM, Jansson JH, Boman K, Nilsson TK, Weinehall L, Huhtasaari F et al. High plasminogen activator inhibitor and tissue plasminogen activator levels in plasma precede a first acute myocardial infraction in both men and women: evidence for the fibrinolytic system as an independent primary risk factor. Circulation 1998;98:2241-7.
-
(1998)
Circulation
, vol.98
, pp. 2241-2247
-
-
Thogersen, A.M.1
Jansson, J.H.2
Boman, K.3
Nilsson, T.K.4
Weinehall, L.5
Huhtasaari, F.6
-
116
-
-
0028559189
-
Body mass index and blood pressures in Korean men and women: the Korean National Blood Pressure Survey
-
Jones DW, Kim JS, Andrew ME, Kim SJ, Hong YP. Body mass index and blood pressures in Korean men and women: the Korean National Blood Pressure Survey. J Hypertens 1994;12:1433-7.
-
(1994)
J Hypertens
, vol.12
, pp. 1433-1437
-
-
Jones, D.W.1
Kim, J.S.2
Andrew, M.E.3
Kim, S.J.4
Hong, Y.P.5
-
117
-
-
0023204243
-
Incidence and precursors of hypertension in young adults: the Framingham Offspring Study
-
Garrison RJ, Kannel WB, Stokes J 3rd, Castelli WP. Incidence and precursors of hypertension in young adults: the Framingham Offspring Study. Prev Med 1987;16:234-51.
-
(1987)
Prev Med
, vol.16
, pp. 234-251
-
-
Garrison, R.J.1
Kannel, W.B.2
Stokes, J.3
Castelli, W.P.4
-
118
-
-
0026058888
-
Relationship between insulin resistance and hypertension
-
Reaven GM. Relationship between insulin resistance and hypertension. Diabetes Care 1991;14:33-8.
-
(1991)
Diabetes Care
, vol.14
, pp. 33-38
-
-
Reaven, G.M.1
-
119
-
-
0034171120
-
Pathophysiology of obesity hypertension
-
Hall JE. Pathophysiology of obesity hypertension. Curr Hypertens Rep 2000;2:139-47.
-
(2000)
Curr Hypertens Rep
, vol.2
, pp. 139-147
-
-
Hall, J.E.1
-
120
-
-
77952893301
-
Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins
-
Hall JE, da Silva AA, do Carmo JM, Dubinion J, Hamza S, Munusamy S et al. Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins. J Biol Chem 2010;285:17271-6.
-
(2010)
J Biol Chem
, vol.285
, pp. 17271-17276
-
-
Hall, J.E.1
da Silva, A.A.2
do Carmo, J.M.3
Dubinion, J.4
Hamza, S.5
Munusamy, S.6
-
121
-
-
84925360037
-
Leptin mediates the increase in blood pressure associated with obesity
-
Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM et al. Leptin mediates the increase in blood pressure associated with obesity. Cell 2014;159:1404-16.
-
(2014)
Cell
, vol.159
, pp. 1404-1416
-
-
Simonds, S.E.1
Pryor, J.T.2
Ravussin, E.3
Greenway, F.L.4
Dileone, R.5
Allen, A.M.6
-
122
-
-
84902037717
-
The role of adiponectin in endothelial dysfunction and hypertension
-
Rojas E, Rodríguez-Molina D, Bolli P, Israili ZH, Faría J, Fidilio E et al. The role of adiponectin in endothelial dysfunction and hypertension. Curr Hypertens Rep 2014;16:463.
-
(2014)
Curr Hypertens Rep
, vol.16
, pp. 463
-
-
Rojas, E.1
Rodríguez-Molina, D.2
Bolli, P.3
Israili, Z.H.4
Faría, J.5
Fidilio, E.6
-
123
-
-
0345492466
-
C-reactive protein and the risk of developing hypertension
-
Sesso HD, Buring JE, Rifai N, Blake GJ, Gaziano JM, Ridker PM. C-reactive protein and the risk of developing hypertension. JAMA 2003;290:2945-51.
-
(2003)
JAMA
, vol.290
, pp. 2945-2951
-
-
Sesso, H.D.1
Buring, J.E.2
Rifai, N.3
Blake, G.J.4
Gaziano, J.M.5
Ridker, P.M.6
-
124
-
-
0026567856
-
Energy expenditure under free-living conditions in normal-weight and overweight women
-
Welle S, Forbes GB, Statt M, Barnard RR, Amatruda JM. Energy expenditure under free-living conditions in normal-weight and overweight women. Am J Clin Nutr 1992;55:14-21.
-
(1992)
Am J Clin Nutr
, vol.55
, pp. 14-21
-
-
Welle, S.1
Forbes, G.B.2
Statt, M.3
Barnard, R.R.4
Amatruda, J.M.5
-
125
-
-
66849091906
-
Estimating the changes in energy flux that characterize the rise in obesity prevalence
-
Swinburn BA, Sacks G, Lo SK, Westerterp KR, Rush EC, Rosenbaum M et al. Estimating the changes in energy flux that characterize the rise in obesity prevalence. Am J Clin Nutr 2009;89:1723-8.
-
(2009)
Am J Clin Nutr
, vol.89
, pp. 1723-1728
-
-
Swinburn, B.A.1
Sacks, G.2
Lo, S.K.3
Westerterp, K.R.4
Rush, E.C.5
Rosenbaum, M.6
-
126
-
-
0008358181
-
The companionship of lean and fat
-
Ellis KJ, Eastman JD, editors. New York, NY: Plenum Press
-
Forbes GB. The companionship of lean and fat. In: Ellis KJ, Eastman JD, editors. Human Body Composition. New York, NY: Plenum Press; 1993: pp 3-14.
-
(1993)
Human Body Composition
, pp. 3-14
-
-
Forbes, G.B.1
-
127
-
-
33644697339
-
Independent association of insulin resistance with larger amounts of intermuscular adipose tissue and a greater acute insulin response to glucose in African American than in white nondiabetic women
-
Albu JB, Kovera AJ, Allen L, Wainwright M, Berk E, Raja-Khan N et al. Independent association of insulin resistance with larger amounts of intermuscular adipose tissue and a greater acute insulin response to glucose in African American than in white nondiabetic women. Am J Clin Nutr 2005;82:1210-7.
-
(2005)
Am J Clin Nutr
, vol.82
, pp. 1210-1217
-
-
Albu, J.B.1
Kovera, A.J.2
Allen, L.3
Wainwright, M.4
Berk, E.5
Raja-Khan, N.6
-
128
-
-
84892620423
-
Insulin and extremity muscle mass in overweight and obese women
-
Leon B, Jenkins S, Pepin K, Chaudhry H, Smith K, Zalos G et al. Insulin and extremity muscle mass in overweight and obese women. Int J Obes (Lond) 2013;37:1560-4.
-
(2013)
Int J Obes (Lond)
, vol.37
, pp. 1560-1564
-
-
Leon, B.1
Jenkins, S.2
Pepin, K.3
Chaudhry, H.4
Smith, K.5
Zalos, G.6
-
129
-
-
84918819322
-
Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease
-
Shulman GI. Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease. N Engl J Med 2014;371:1131-41.
-
(2014)
N Engl J Med
, vol.371
, pp. 1131-1141
-
-
Shulman, G.I.1
-
130
-
-
5044242948
-
Bariatric surgery: a systematic review and meta-analysis
-
Review. Erratum in: JAMA. 2005;293:1728.
-
Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 2004;292:1724-37. Review. Erratum in: JAMA. 2005;293:1728.
-
(2004)
JAMA
, vol.292
, pp. 1724-1737
-
-
Buchwald, H.1
Avidor, Y.2
Braunwald, E.3
Jensen, M.D.4
Pories, W.5
Fahrbach, K.6
-
131
-
-
78751612608
-
Bariatric surgery: results in obesity and effects on metabolic parameters
-
Clifton PM. Bariatric surgery: results in obesity and effects on metabolic parameters. Curr Opin Lipidol 2011;22:1-5.
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 1-5
-
-
Clifton, P.M.1
-
132
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;346:393-403.
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
-
133
-
-
17144389303
-
The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial
-
Orchard TJ, Temprosa M, Goldberg R, Haffner S, Ratner R, Marcovina S et al. The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann Intern Med 2005;142:611-9.
-
(2005)
Ann Intern Med
, vol.142
, pp. 611-619
-
-
Orchard, T.J.1
Temprosa, M.2
Goldberg, R.3
Haffner, S.4
Ratner, R.5
Marcovina, S.6
-
134
-
-
84865458808
-
Targeting the consequences of the metabolic syndrome in the Diabetes Prevention Program
-
Goldberg RB, Mather K. Targeting the consequences of the metabolic syndrome in the Diabetes Prevention Program. Arterioscler Thromb Vasc Biol 2012;32:2077-90.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2077-2090
-
-
Goldberg, R.B.1
Mather, K.2
-
135
-
-
0019603446
-
The, "metabolically-obese", normal-weight individual
-
Ruderman NB, Schneider SH, Berchtold P. The, "metabolically-obese", normal-weight individual. Am J Clin Nutr 1981;34:1617-21.
-
(1981)
Am J Clin Nutr
, vol.34
, pp. 1617-1621
-
-
Ruderman, N.B.1
Schneider, S.H.2
Berchtold, P.3
-
136
-
-
34547911800
-
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
-
Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S et al. The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proc Natl Acad Sci U S A 2007;104:12587-94.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12587-12594
-
-
Petersen, K.F.1
Dufour, S.2
Savage, D.B.3
Bilz, S.4
Solomon, G.5
Yonemitsu, S.6
-
137
-
-
77955642542
-
The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome
-
Jornayvaz FR, Samuel VT, Shulman GI. The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome. Annu Rev Nutr 2010;30:273-90.
-
(2010)
Annu Rev Nutr
, vol.30
, pp. 273-290
-
-
Jornayvaz, F.R.1
Samuel, V.T.2
Shulman, G.I.3
-
138
-
-
34248582679
-
Insulin resistance and metabolic syndrome in children of parents with diabetes mellitus
-
Altinli S, Elevli M, Ozkul AA, Kara PG, Karsidag K, Dogru M. Insulin resistance and metabolic syndrome in children of parents with diabetes mellitus. J Pediatr Endocrinol Metab 2007;20:431-6.
-
(2007)
J Pediatr Endocrinol Metab
, vol.20
, pp. 431-436
-
-
Altinli, S.1
Elevli, M.2
Ozkul, A.A.3
Kara, P.G.4
Karsidag, K.5
Dogru, M.6
-
139
-
-
73649128343
-
The metabolic syndrome in South Asians: epidemiology, determinants, and prevention
-
Misra A, Khurana L. The metabolic syndrome in South Asians: epidemiology, determinants, and prevention. Metab Syndr Relat Disord 2009;7:497-514.
-
(2009)
Metab Syndr Relat Disord
, vol.7
, pp. 497-514
-
-
Misra, A.1
Khurana, L.2
-
140
-
-
33845209360
-
Metabolic syndrome prevalence and characteristics in Greek adults with familial combined hyperlipidemia
-
Skoumas J, Papadimitriou L, Pitsavos C, Masoura C, Giotsas N, Chrysohoou C et al. Metabolic syndrome prevalence and characteristics in Greek adults with familial combined hyperlipidemia. Metabolism 2007;56:135-41.
-
(2007)
Metabolism
, vol.56
, pp. 135-141
-
-
Skoumas, J.1
Papadimitriou, L.2
Pitsavos, C.3
Masoura, C.4
Giotsas, N.5
Chrysohoou, C.6
-
142
-
-
33645470211
-
Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy
-
Grundy SM. Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy. Nat Rev Drug Discov 2006;5:295-309.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 295-309
-
-
Grundy, S.M.1
|