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Volumn 11, Issue 1, 2015, Pages 1-15

Tissue stiffness dictates development, homeostasis, and disease progression

Author keywords

Cancer; Extracellular matrix; Fibrosis; Stiffness; Tissue development; Tissue homeostasis

Indexed keywords

COLLAGEN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84945175634     PISSN: 15476278     EISSN: 15558592     Source Type: Journal    
DOI: 10.1080/15476278.2015.1019687     Document Type: Review
Times cited : (487)

References (98)
  • 1
    • 0029731588 scopus 로고    scopus 로고
    • Focal adhesions, contractility, and signaling
    • PMID: 8970735
    • Burridge K, Chrzanowska-Wodnicka M. Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol 1996; 12: 463-518; PMID: 8970735; http://dx. doi. org/10. 1146/annurev. cellbio. 12. 1. 463.
    • (1996) Annu Rev Cell Dev Biol , vol.12 , pp. 463-518
    • Burridge, K.1    Chrzanowska-Wodnicka, M.2
  • 2
    • 33748443594 scopus 로고    scopus 로고
    • Regulation of cellcell junctions by the cytoskeleton
    • PMID: 16905303
    • Mege RM, Gavard J, Lambert M. Regulation of cellcell junctions by the cytoskeleton. Curr Opin Cell Biol 2006; 18: 541-8; PMID: 16905303; http://dx. doi. org/10. 1016/j. ceb. 2006. 08. 004.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 541-548
    • Mege, R.M.1    Gavard, J.2    Lambert, M.3
  • 3
    • 84924873756 scopus 로고    scopus 로고
    • Ncadherin negatively regulates collective drosophila glial migration via actin cytoskeleton remodeling
    • PMID: 25593128
    • Kumar A, Gupta T, Berzsenyi S, Giangrande A. Ncadherin negatively regulates collective drosophila glial migration via actin cytoskeleton remodeling. J Cell Sci 2015; 128: 900-12; PMID: 25593128.
    • (2015) J Cell Sci , vol.128 , pp. 900-912
    • Kumar, A.1    Gupta, T.2    Berzsenyi, S.3    Giangrande, A.4
  • 4
    • 84887351931 scopus 로고    scopus 로고
    • p21-Activated kinase (PAK) is required for bone morphogenetic protein (BMP)-induced dendritogenesis in cortical neurons
    • PMID: 24141051
    • Podkowa M, Christova T, Zhao X, Jian Y, Attisano L. p21-Activated kinase (PAK) is required for bone morphogenetic protein (BMP)-induced dendritogenesis in cortical neurons. Mol Cellular Neurosci 2013; 57: 83-92; PMID: 24141051; http://dx. doi. org/10. 1016/j. mcn. 2013. 10. 005.
    • (2013) Mol Cellular Neurosci , vol.57 , pp. 83-92
    • Podkowa, M.1    Christova, T.2    Zhao, X.3    Jian, Y.4    Attisano, L.5
  • 5
    • 84923587504 scopus 로고    scopus 로고
    • Actin cytoskeletal control during epithelial to mesenchymal transition: Focus on the pancreas and intestinal tract
    • PMID: 25611303
    • Morris HT, Machesky LM. Actin cytoskeletal control during epithelial to mesenchymal transition: focus on the pancreas and intestinal tract. British J Cancer 2015; 112: 613-20; PMID: 25611303; http://dx. doi. org/10. 1038/bjc. 2014. 658.
    • (2015) British J Cancer , vol.112 , pp. 613-620
    • Morris, H.T.1    Machesky, L.M.2
  • 7
    • 84904723706 scopus 로고    scopus 로고
    • Selective regulation of cytoskeletal tension and cell-matrix adhesion by RhoA and Src
    • PMID: 24984203
    • Sreenivasappa H, Chaki SP, Lim SM, Trzeciakowski JP, Davidson MW, Rivera GM, Trache A. Selective regulation of cytoskeletal tension and cell-matrix adhesion by RhoA and Src. Int Biol 2014; 6: 743-54; PMID: 24984203; http://dx. doi. org/10. 1039/c4ib00019f.
    • (2014) Int Biol , vol.6 , pp. 743-754
    • Sreenivasappa, H.1    Chaki, S.P.2    Lim, S.M.3    Trzeciakowski, J.P.4    Davidson, M.W.5    Rivera, G.M.6    Trache, A.7
  • 8
    • 84903168767 scopus 로고    scopus 로고
    • A FAK-Cas-Raclamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling
    • PMID: 24939893
    • Bae YH, Mui KL, Hsu BY, Liu SL, Cretu A, Razinia Z, Xu T, Puré E, Assoian RK. A FAK-Cas-Raclamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling. Sci Signaling 2014; 7: ra57; PMID: 24939893; http://dx. doi. org/10. 1126/scisignal. 2004838.
    • (2014) Sci Signaling , vol.7
    • Bae, Y.H.1    Mui, K.L.2    Hsu, B.Y.3    Liu, S.L.4    Cretu, A.5    Razinia, Z.6    Xu, T.7    Puré, E.8    Assoian, R.K.9
  • 9
    • 84902775661 scopus 로고    scopus 로고
    • Integrins in periodontal disease
    • PMID: 24662197
    • Larjava H, Koivisto L, Heino J, Hakkinen L. Integrins in periodontal disease. Exp Cell Res 2014; 325: 104-10; PMID: 24662197; http://dx. doi. org/10. 1016/j. yexcr. 2014. 03. 010.
    • (2014) Exp Cell Res , vol.325 , pp. 104-110
    • Larjava, H.1    Koivisto, L.2    Heino, J.3    Hakkinen, L.4
  • 10
    • 77951096447 scopus 로고    scopus 로고
    • Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer
    • PMID: 20101634
    • Guan JL. Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer. Iubmb Life 2010; 62: 268-76; PMID: 20101634; http://dx. doi. org/10. 1002/iub. 311.
    • (2010) Iubmb Life , vol.62 , pp. 268-276
    • Guan, J.L.1
  • 11
    • 79955727135 scopus 로고    scopus 로고
    • The dual kinase complex FAK-Src as a promising therapeutic target in cancer
    • PMID: 20616959
    • Bolos V, Gasent JM, Lopez-Tarruella S, Grande E. The dual kinase complex FAK-Src as a promising therapeutic target in cancer. Oncotargets Ther 2010; 3: 83-97; PMID: 20616959; http://dx. doi. org/10. 2147/OTT. S6909.
    • (2010) Oncotargets Ther , vol.3 , pp. 83-97
    • Bolos, V.1    Gasent, J.M.2    Lopez-Tarruella, S.3    Grande, E.4
  • 12
    • 84871591464 scopus 로고    scopus 로고
    • Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration
    • PMID: 23260139
    • Plotnikov SV, Pasapera AM, Sabass B, Waterman CM. Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration. Cell 2012; 151: 1513-27; PMID: 23260139; http://dx. doi. org/10. 1016/j. cell. 2012. 11. 034.
    • (2012) Cell , vol.151 , pp. 1513-1527
    • Plotnikov, S.V.1    Pasapera, A.M.2    Sabass, B.3    Waterman, C.M.4
  • 13
    • 79953066426 scopus 로고    scopus 로고
    • Matrix stiffness regulation of integrin-mediated mechanotransduction during osteogenic differentiation of human mesenchymal stem cells
    • PMID: 20939067
    • Shih YR, Tseng KF, Lai HY, Lin CH, Lee OK. Matrix stiffness regulation of integrin-mediated mechanotransduction during osteogenic differentiation of human mesenchymal stem cells. J Bone Min Res 2011; 26: 730-8; PMID: 20939067; http://dx. doi. org/10. 1002/jbmr. 278.
    • (2011) J Bone Min Res , vol.26 , pp. 730-738
    • Shih, Y.R.1    Tseng, K.F.2    Lai, H.Y.3    Lin, C.H.4    Lee, O.K.5
  • 14
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • PMID: 16212495
    • Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 2005; 21: 247-69; PMID: 16212495; http://dx. doi. org/10. 1146/annurev. cellbio. 21. 020604. 150721.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 15
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac take center stage
    • PMID: 14744429
    • Burridge K, Wennerberg K. Rho and Rac take center stage. Cell 2004; 116: 167-79; PMID: 14744429; http://dx. doi. org/10. 1016/S0092-8674(04)00003-0.
    • (2004) Cell , vol.116 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2
  • 16
    • 0038024241 scopus 로고    scopus 로고
    • Rocks: Multifunctional kinases in cell behaviour
    • PMID: 12778124
    • Riento K, Ridley AJ. Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 2003; 4: 446-56; PMID: 12778124; http://dx. doi. org/10. 1038/nrm1128.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 446-456
    • Riento, K.1    Ridley, A.J.2
  • 17
    • 34248154652 scopus 로고    scopus 로고
    • Mechanism and function of formins in the control of actin assembly
    • PMID: 17373907
    • Goode BL, Eck MJ. Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem 2007; 76: 593-627; PMID: 17373907; http://dx. doi. org/10. 1146/annurev. biochem. 75. 103004. 142647.
    • (2007) Annu Rev Biochem , vol.76 , pp. 593-627
    • Goode, B.L.1    Eck, M.J.2
  • 19
    • 84865121019 scopus 로고    scopus 로고
    • Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction
    • PMID: 22461426
    • Huang X, Yang N, Fiore VF, Barker TH, Sun Y, Morris SW, Ding Q, Thannickal VJ, Zhou Y. Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction. Am J Resp Cell Mol Biol 2012; 47: 340-8; PMID: 22461426; http://dx. doi. org/10. 1165/rcmb. 2012-0050OC.
    • (2012) Am J Resp Cell Mol Biol , vol.47 , pp. 340-348
    • Huang, X.1    Yang, N.2    Fiore, V.F.3    Barker, T.H.4    Sun, Y.5    Morris, S.W.6    Ding, Q.7    Thannickal, V.J.8    Zhou, Y.9
  • 20
    • 84915784640 scopus 로고    scopus 로고
    • Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium
    • PMID: 24930031
    • Chaudhuri O, Koshy ST, Branco da Cunha C, Shin JW, Verbeke CS, Allison KH, Mooney DJ. Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium. Nat Materials 2014; 13: 970-8; PMID: 24930031; http://dx. doi. org/10. 1038/nmat4009.
    • (2014) Nat Materials , vol.13 , pp. 970-978
    • Chaudhuri, O.1    Koshy, S.T.2    Branco da Cunha, C.3    Shin, J.W.4    Verbeke, C.S.5    Allison, K.H.6    Mooney, D.J.7
  • 21
    • 0024988663 scopus 로고
    • Three-dimensional organization of extracellular matrix in elastic cartilage as viewed by quick freeze, deep etch electron microscopy
    • PMID: 2354636
    • Mecham RP, Heuser J. Three-dimensional organization of extracellular matrix in elastic cartilage as viewed by quick freeze, deep etch electron microscopy. Connect Tissue Res 1990; 24: 83-93; PMID: 2354636; http://dx. doi. org/10. 3109/03008-209009152425.
    • (1990) Connect Tissue Res , vol.24 , pp. 83-93
    • Mecham, R.P.1    Heuser, J.2
  • 22
    • 0034285081 scopus 로고    scopus 로고
    • Fibroblast-collagen-matrix contraction: Growth-factor signalling and mechanical loading
    • PMID: 10932093
    • Grinnell F. Fibroblast-collagen-matrix contraction: growth-factor signalling and mechanical loading. Trends Cell Biol 2000; 10: 362-5; PMID: 10932093; http://dx. doi. org/10. 1016/S0962-8924(00)01802-X.
    • (2000) Trends Cell Biol , vol.10 , pp. 362-365
    • Grinnell, F.1
  • 23
    • 27144473914 scopus 로고    scopus 로고
    • The extracellular matrix guides the orientation of the cell division axis
    • PMID: 16179950
    • Thery M, Racine V, Pepin A, Piel M, Chen Y, Sibarita JB, Bornens M. The extracellular matrix guides the orientation of the cell division axis. Nat Cell Biol 2005; 7: 947-53; PMID: 16179950; http://dx. doi. org/10. 1038/ncb1307.
    • (2005) Nat Cell Biol , vol.7 , pp. 947-953
    • Thery, M.1    Racine, V.2    Pepin, A.3    Piel, M.4    Chen, Y.5    Sibarita, J.B.6    Bornens, M.7
  • 24
    • 64549110806 scopus 로고    scopus 로고
    • Actomyosin stiffens the vertebrate embryo during crucial stages of elongation and neural tube closure
    • PMID: 19168681
    • Zhou J, Kim HY, Davidson LA. Actomyosin stiffens the vertebrate embryo during crucial stages of elongation and neural tube closure. Devel 2009; 136: 677-88; PMID: 19168681; http://dx. doi. org/10. 1242/dev. 026211.
    • (2009) Devel , vol.136 , pp. 677-688
    • Zhou, J.1    Kim, H.Y.2    Davidson, L.A.3
  • 25
    • 84862990847 scopus 로고    scopus 로고
    • An actomyosin-based barrier inhibits cell mixing at compartmental boundaries in drosophila embryos
    • PMID: 19966783
    • Monier B, Pelissier-Monier A, Brand AH, Sanson B. An actomyosin-based barrier inhibits cell mixing at compartmental boundaries in drosophila embryos. Nat Cell Biol 2010; 12: 60-5: 1-9; PMID: 19966783; http://dx. doi. org/10. 1038/ncb2005.
    • (2010) Nat Cell Biol , vol.12 , Issue.60-65 , pp. 1-9
    • Monier, B.1    Pelissier-Monier, A.2    Brand, A.H.3    Sanson, B.4
  • 26
    • 70450283823 scopus 로고    scopus 로고
    • Myosin II dynamics are regulated by tension in intercalating cells
    • PMID: 19879198
    • Fernandez-Gonzalez R, Simoes Sde M, Roper JC, Eaton S, Zallen JA. Myosin II dynamics are regulated by tension in intercalating cells. Dev Cell 2009; 17: 736-43; PMID: 19879198; http://dx. doi. org/10. 1016/j. devcel. 2009. 09. 003.
    • (2009) Dev Cell , vol.17 , pp. 736-743
    • Fernandez-Gonzalez, R.1    Simoes Sde, M.2    Roper, J.C.3    Eaton, S.4    Zallen, J.A.5
  • 27
    • 77951217199 scopus 로고    scopus 로고
    • Apical constriction: A cell shape change that can drive morphogenesis
    • PMID: 19751720
    • Sawyer JM, Harrell JR, Shemer G, Sullivan-Brown J, Roh-Johnson M, Goldstein B. Apical constriction: a cell shape change that can drive morphogenesis. Dev Biol 2010; 341: 5-19; PMID: 19751720; http://dx. doi. org/10. 1016/j. ydbio. 2009. 09. 009.
    • (2010) Dev Biol , vol.341 , pp. 5-19
    • Sawyer, J.M.1    Harrell, J.R.2    Shemer, G.3    Sullivan-Brown, J.4    Roh-Johnson, M.5    Goldstein, B.6
  • 28
    • 0035949694 scopus 로고    scopus 로고
    • Focal adhesion kinase is involved in mechanosensing during fibroblast migration
    • PMID: 11572981
    • Wang HB, Dembo M, Hanks SK, Wang Y. Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proc Natl Acad Sci U S A 2001; 98: 11295-300; PMID: 11572981; http://dx. doi. org/10. 1073/pnas. 201201198.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11295-11300
    • Wang, H.B.1    Dembo, M.2    Hanks, S.K.3    Wang, Y.4
  • 29
    • 12344296398 scopus 로고    scopus 로고
    • Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension
    • PMID: 15614768
    • Moore KA, Polte T, Huang S, Shi B, Alsberg E, Sunday ME, Ingber DE. Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. Dev Dyn 2005; 232: 268-81; PMID: 15614768; http://dx. doi. org/10. 1002/dvdy. 20237.
    • (2005) Dev Dyn , vol.232 , pp. 268-281
    • Moore, K.A.1    Polte, T.2    Huang, S.3    Shi, B.4    Alsberg, E.5    Sunday, M.E.6    Ingber, D.E.7
  • 30
    • 0020070969 scopus 로고
    • Glycosaminoglycans in the basal lamina and extracellular matrix of the developing mouse mammary duct
    • PMID: 6800862
    • Silberstein GB, Daniel CW. Glycosaminoglycans in the basal lamina and extracellular matrix of the developing mouse mammary duct. Dev Biol 1982; 90: 215-22; PMID: 6800862; http://dx. doi. org/10. 1016/0012-1606(82)90228-7.
    • (1982) Dev Biol , vol.90 , pp. 215-222
    • Silberstein, G.B.1    Daniel, C.W.2
  • 31
    • 0023251107 scopus 로고
    • Reversible inhibition of mammary gland growth by transforming growth factor-b
    • PMID: 3474783
    • Silberstein GB, Daniel CW. Reversible inhibition of mammary gland growth by transforming growth factor-b. Science 1987; 237: 291-3; PMID: 3474783; http://dx. doi. org/10. 1126/science. 3474783.
    • (1987) Science , vol.237 , pp. 291-293
    • Silberstein, G.B.1    Daniel, C.W.2
  • 32
    • 0000463651 scopus 로고    scopus 로고
    • The structural and mechanical complexity of cell-growth control
    • PMID: 10559956
    • Huang S, Ingber DE. The structural and mechanical complexity of cell-growth control. Nat Cell Biol 1999; 1: E131-8; PMID: 10559956; http://dx. doi. org/10. 1038/13043.
    • (1999) Nat Cell Biol , vol.1 , pp. E131-E138
    • Huang, S.1    Ingber, D.E.2
  • 33
    • 33749992857 scopus 로고    scopus 로고
    • Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures
    • PMID: 17038622
    • Nelson CM, Vanduijn MM, Inman JL, Fletcher DA, Bissell MJ. Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures. Science 2006; 314: 298-300; PMID: 17038622; http://dx. doi. org/10. 1126/science. 1131000.
    • (2006) Science , vol.314 , pp. 298-300
    • Nelson, C.M.1    Vanduijn, M.M.2    Inman, J.L.3    Fletcher, D.A.4    Bissell, M.J.5
  • 34
  • 35
    • 0020313032 scopus 로고
    • Extracellular matrix promotes mammary epithelial growth and differentiation in vitro
    • PMID: 6954472
    • Wicha MS, Lowrie G, Kohn E, Bagavandoss P, Mahn T. Extracellular matrix promotes mammary epithelial growth and differentiation in vitro. Proc Natl Acad Sci U S A 1982; 79: 3213-7; PMID: 6954472; http://dx. doi. org/10. 1073/pnas. 79. 10. 3213.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 3213-3217
    • Wicha, M.S.1    Lowrie, G.2    Kohn, E.3    Bagavandoss, P.4    Mahn, T.5
  • 36
    • 0022968516 scopus 로고
    • A possible mechanism for inhibition of angiogenesis by angiostatic steroids: Induction of capillary basement membrane dissolution
    • PMID: 2428602
    • Ingber DE, Madri JA, Folkman J. A possible mechanism for inhibition of angiogenesis by angiostatic steroids: induction of capillary basement membrane dissolution. Endocrinology 1986; 119: 1768-75; PMID: 2428602; http://dx. doi. org/10. 1210/endo-119-4-1768.
    • (1986) Endocrinology , vol.119 , pp. 1768-1775
    • Ingber, D.E.1    Madri, J.A.2    Folkman, J.3
  • 37
    • 1242281665 scopus 로고    scopus 로고
    • Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium
    • PMID: 14707027
    • Lahmers S, Wu Y, Call DR, Labeit S, Granzier H. Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium. Circ Res 2004; 94: 505-13; PMID: 14707027; http://dx. doi. org/10. 1161/01. RES. 0000115522. 52554. 86.
    • (2004) Circ Res , vol.94 , pp. 505-513
    • Lahmers, S.1    Wu, Y.2    Call, D.R.3    Labeit, S.4    Granzier, H.5
  • 40
    • 62649122464 scopus 로고    scopus 로고
    • The regulative role of neurite mechanical tension in network development
    • PMID: 19217881
    • Anava S, Greenbaum A, Ben Jacob E, Hanein Y, Ayali A. The regulative role of neurite mechanical tension in network development. Biophys J 2009; 96: 1661-70; PMID: 19217881; http://dx. doi. org/10. 1016/j. bpj. 2008. 10. 058.
    • (2009) Biophys J , vol.96 , pp. 1661-1670
    • Anava, S.1    Greenbaum, A.2    Ben Jacob, E.3    Hanein, Y.4    Ayali, A.5
  • 41
    • 37249034106 scopus 로고    scopus 로고
    • Synaptic reorganization in scaled networks of controlled size
    • PMID: 18077670
    • Wilson NR, Ty MT, Ingber DE, Sur M, Liu G. Synaptic reorganization in scaled networks of controlled size. J Neurosci 2007; 27: 13581-9; PMID: 18077670; http://dx. doi. org/10. 1523/JNEUROSCI. 3863-07. 2007.
    • (2007) J Neurosci , vol.27 , pp. 13581-13589
    • Wilson, N.R.1    Ty, M.T.2    Ingber, D.E.3    Sur, M.4    Liu, G.5
  • 42
    • 0036006297 scopus 로고    scopus 로고
    • Endothelial signaling in kidney morphogenesis: A role for hemodynamic forces
    • PMID: 11909536
    • Serluca FC, Drummond IA, Fishman MC. Endothelial signaling in kidney morphogenesis: a role for hemodynamic forces. Current biology: CB 2002; 12: 492-7; PMID: 11909536; http://dx. doi. org/10. 1016/S0960-9822(02)00694-2.
    • (2002) Current biology: CB , vol.12 , pp. 492-497
    • Serluca, F.C.1    Drummond, I.A.2    Fishman, M.C.3
  • 47
    • 0036336506 scopus 로고    scopus 로고
    • Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation
    • PMID: 11923206
    • Wei L, Imanaka-Yoshida K, Wang L, Zhan S, Schneider MD, DeMayo FJ, Schwartz RJ. Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation. Dev 2002; 129: 1705-14; PMID: 11923206.
    • (2002) Dev , vol.129 , pp. 1705-1714
    • Wei, L.1    Imanaka-Yoshida, K.2    Wang, L.3    Zhan, S.4    Schneider, M.D.5    DeMayo, F.J.6    Schwartz, R.J.7
  • 49
    • 33749259836 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator (CFTR) dependent cytoskeletal tension during lung organogenesis
    • PMID: 16906518
    • Cohen JC, Larson JE. Cystic fibrosis transmembrane conductance regulator (CFTR) dependent cytoskeletal tension during lung organogenesis. Dev Dyn 2006; 235: 2736-48; PMID: 16906518; http://dx. doi. org/10. 1002/dvdy. 20912.
    • (2006) Dev Dyn , vol.235 , pp. 2736-2748
    • Cohen, J.C.1    Larson, J.E.2
  • 50
    • 65949097929 scopus 로고    scopus 로고
    • ECM compliance regulates osteogenesis by influencing MAPK signaling downstream of RhoA and ROCK
    • PMID: 19113908
    • Khatiwala CB, Kim PD, Peyton SR, Putnam AJ. ECM compliance regulates osteogenesis by influencing MAPK signaling downstream of RhoA and ROCK. J Bone Mineral Res 2009; 24: 886-98; PMID: 19113908; http://dx. doi. org/10. 1359/jbmr. 081240.
    • (2009) J Bone Mineral Res , vol.24 , pp. 886-898
    • Khatiwala, C.B.1    Kim, P.D.2    Peyton, S.R.3    Putnam, A.J.4
  • 51
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • PMID: 16923388
    • Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell 2006; 126: 677-89; PMID: 16923388; http://dx. doi. org/10. 1016/j. cell. 2006. 06. 044.
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 52
    • 0031012936 scopus 로고    scopus 로고
    • Bone mass homeostasis and bisphosphonate action
    • PMID: 8988341
    • Rodan GA. Bone mass homeostasis and bisphosphonate action. Bone 1997; 20: 1-4; PMID: 8988341; http://dx. doi. org/10. 1016/S8756-3282(96)00318-3.
    • (1997) Bone , vol.20 , pp. 1-4
    • Rodan, G.A.1
  • 53
    • 84865863655 scopus 로고    scopus 로고
    • In situ chondrocyte viscoelasticity
    • PMID: 22884037
    • Han SK, Madden R, Abusara Z, Herzog W. In situ chondrocyte viscoelasticity. J Biomech 2012; 45: 2450-6; PMID: 22884037; http://dx. doi. org/10. 1016/j. jbiomech. 2012. 06. 028.
    • (2012) J Biomech , vol.45 , pp. 2450-2456
    • Han, S.K.1    Madden, R.2    Abusara, Z.3    Herzog, W.4
  • 54
    • 84904293483 scopus 로고    scopus 로고
    • EPCs in vascular repair: How can we clear the hurdles between bench and bedside?
    • PMID: 24389171
    • Lu CH, Zhang J, Zhang DH, Uzan G, Li MQ. EPCs in vascular repair: How can we clear the hurdles between bench and bedside? Front Biosci-Landmrk 2014; 19: 34-48; PMID: 24389171; http://dx. doi. org/10. 2741/4194.
    • (2014) Front Biosci-Landmrk , vol.19 , pp. 34-48
    • Lu, C.H.1    Zhang, J.2    Zhang, D.H.3    Uzan, G.4    Li, M.Q.5
  • 55
    • 84880174251 scopus 로고    scopus 로고
    • Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling
    • PMID: 23840100
    • Chen QS, Jin M, Yang F, Zhu JH, Xiao QZ, Zhang L. Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling. Mediat Inflamm 2013; 2013: 928315; PMID: 23840100; http://dx. doi. org/10. 1155/2013/928315.
    • (2013) Mediat Inflamm , vol.2013
    • Chen, Q.S.1    Jin, M.2    Yang, F.3    Zhu, J.H.4    Xiao, Q.Z.5    Zhang, L.6
  • 56
    • 77957695890 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells
    • PMID: 19968735
    • Hanjaya-Putra D, Yee J, Ceci D, Truitt R, Yee D, Gerecht S. Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells. J Cell Mol Med 2010; 14: 2436-47; PMID: 19968735; http://dx. doi. org/10. 1111/j. 1582-4934. 2009. 00981. x.
    • (2010) J Cell Mol Med , vol.14 , pp. 2436-2447
    • Hanjaya-Putra, D.1    Yee, J.2    Ceci, D.3    Truitt, R.4    Yee, D.5    Gerecht, S.6
  • 57
    • 33646204388 scopus 로고    scopus 로고
    • Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures
    • PMID: 16461391
    • Georges PC, Miller WJ, Meaney DF, Sawyer ES, Janmey PA. Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures. Biophys J 2006; 90: 3012-8; PMID: 16461391; http://dx. doi. org/10. 1529/biophysj. 105. 073114.
    • (2006) Biophys J , vol.90 , pp. 3012-3018
    • Georges, P.C.1    Miller, W.J.2    Meaney, D.F.3    Sawyer, E.S.4    Janmey, P.A.5
  • 58
    • 0141938065 scopus 로고    scopus 로고
    • International Standards for Neurological and Functional Classification of Spinal Cord Injury. American Spinal Injury Association
    • PMID: 9160449
    • Maynard FM, Jr., Bracken MB, Creasey G, Ditunno JF, Jr., Donovan WH, Ducker TB, Garber SL, Marino RJ, Stover SL, Tator CH., et al. International Standards for Neurological and Functional Classification of Spinal Cord Injury. American Spinal Injury Association. Spinal Cord 1997; 35: 266-74; PMID: 9160449; http://dx. doi. org/10. 1038/sj. sc. 3100432.
    • (1997) Spinal Cord , vol.35 , pp. 266-274
    • Maynard, F.M.1    Bracken, M.B.2    Creasey, G.3    Ditunno, J.F.4    Donovan, W.H.5    Ducker, T.B.6    Garber, S.L.7    Marino, R.J.8    Stover, S.L.9    Tator, C.H.10
  • 59
    • 0034718896 scopus 로고    scopus 로고
    • Regenerating the damaged central nervous system
    • PMID: 11069169
    • Horner PJ, Gage FH. Regenerating the damaged central nervous system. Nature 2000; 407: 963-70; PMID: 11069169; http://dx. doi. org/10. 1038/35039559.
    • (2000) Nature , vol.407 , pp. 963-970
    • Horner, P.J.1    Gage, F.H.2
  • 60
    • 4544373293 scopus 로고    scopus 로고
    • Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord
    • PMID: 15341588
    • Camand E, Morel MP, Faissner A, Sotelo C, Dusart I. Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord. Eur J Neurosci 2004; 20: 1161-76; PMID: 15341588; http://dx. doi. org/10. 1111/j. 1460-9568. 2004. 03558. x.
    • (2004) Eur J Neurosci , vol.20 , pp. 1161-1176
    • Camand, E.1    Morel, M.P.2    Faissner, A.3    Sotelo, C.4    Dusart, I.5
  • 61
    • 0032814562 scopus 로고    scopus 로고
    • Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function
    • PMID: 10407127
    • Raivich G, Bohatschek M, Kloss CU, Werner A, Jones LL, Kreutzberg GW. Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 1999; 30: 77-105; PMID: 10407127; http://dx. doi. org/10. 1016/S0165-0173(99)00007-7.
    • (1999) Brain Res Brain Res Rev , vol.30 , pp. 77-105
    • Raivich, G.1    Bohatschek, M.2    Kloss, C.U.3    Werner, A.4    Jones, L.L.5    Kreutzberg, G.W.6
  • 62
    • 84922794805 scopus 로고    scopus 로고
    • Age-related changes in dynamic compressive properties of trochanteric soft tissues over the hip
    • PMID: 25596629
    • Choi WJ, Russell CM, Tsai CM, Arzanpour S, Robinovitch SN. Age-related changes in dynamic compressive properties of trochanteric soft tissues over the hip. J Biomech 2014; PMID: 25596629; http://dx. doi. org/10. 1016/j. jbiomech. 2014. 12. 026.
    • (2014) J Biomech
    • Choi, W.J.1    Russell, C.M.2    Tsai, C.M.3    Arzanpour, S.4    Robinovitch, S.N.5
  • 63
    • 84907332907 scopus 로고    scopus 로고
    • Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice
    • PMID: 24994884
    • Wood LK, Kayupov E, Gumucio JP, Mendias CL, Claflin DR, Brooks SV. Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice. J Appl Physiol 2014; 117: 363-9; PMID: 24994884; http://dx. doi. org/10. 1152/japplphysiol. 00256. 2014.
    • (2014) J Appl Physiol , vol.117 , pp. 363-369
    • Wood, L.K.1    Kayupov, E.2    Gumucio, J.P.3    Mendias, C.L.4    Claflin, D.R.5    Brooks, S.V.6
  • 65
    • 2942622398 scopus 로고    scopus 로고
    • Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking
    • PMID: 15188175
    • Issa R, Zhou X, Constandinou CM, Fallowfield J, Millward-Sadler H, Gaca MD, Gaca MD, Sands E, Suliman I, Trim N., et al. Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology 2004; 126: 1795-808; PMID: 15188175; http://dx. doi. org/10. 1053/j. gastro. 2004. 03. 009.
    • (2004) Gastroenterology , vol.126 , pp. 1795-1808
    • Issa, R.1    Zhou, X.2    Constandinou, C.M.3    Fallowfield, J.4    Millward-Sadler, H.5    Gaca, M.D.6    Gaca, M.D.7    Sands, E.8    Suliman, I.9    Trim, N.10
  • 66
    • 33646573270 scopus 로고    scopus 로고
    • Collagen suprastructures
    • Birk DE, Bruckner P. Collagen suprastructures. Collagen 2005; 247: 185-205.
    • (2005) Collagen , vol.247 , pp. 185-205
    • Birk, D.E.1    Bruckner, P.2
  • 69
    • 54049096780 scopus 로고    scopus 로고
    • Extracellular matrix mechanics in lung parenchymal diseases
    • PMID: 18485836
    • Suki B, Bates JH. Extracellular matrix mechanics in lung parenchymal diseases. Respir Physiol Neurobiol 2008; 163: 33-43; PMID: 18485836; http://dx. doi. org/10. 1016/j. resp. 2008. 03. 015.
    • (2008) Respir Physiol Neurobiol , vol.163 , pp. 33-43
    • Suki, B.1    Bates, J.H.2
  • 70
    • 34548403115 scopus 로고    scopus 로고
    • Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis
    • PMID: 17719831
    • Kass L, Erler JT, Dembo M, Weaver VM. Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. Int J Biochem Cell Biol 2007; 39: 1987-94; PMID: 17719831; http://dx. doi. org/10. 1016/j. biocel. 2007. 06. 025.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1987-1994
    • Kass, L.1    Erler, J.T.2    Dembo, M.3    Weaver, V.M.4
  • 71
    • 58849106652 scopus 로고    scopus 로고
    • A tense situation: Forcing tumour progression
    • PMID: 19165226
    • Butcher DT, Alliston T, Weaver VM. A tense situation: forcing tumour progression. Nat Rev Cancer 2009; 9: 108-22; PMID: 19165226; http://dx. doi. org/10. 1038/nrc2544.
    • (2009) Nat Rev Cancer , vol.9 , pp. 108-122
    • Butcher, D.T.1    Alliston, T.2    Weaver, V.M.3
  • 74
    • 50849145156 scopus 로고    scopus 로고
    • Collagen fibrillogenesis: Fibronectin, integrins, and minor collagens as organizers and nucleators
    • PMID: 18640274
    • Kadler KE, Hill A, Canty-Laird EG. Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators. Curr Opin Cell Biol 2008; 20: 495-501; PMID: 18640274; http://dx. doi. org/10. 1016/j. ceb. 2008. 06. 008.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 495-501
    • Kadler, K.E.1    Hill, A.2    Canty-Laird, E.G.3
  • 76
    • 77957221459 scopus 로고    scopus 로고
    • Dynamic interplay between the collagen scaffold and tumor evolution
    • PMID: 20822891
    • Egeblad M, Rasch MG, Weaver VM. Dynamic interplay between the collagen scaffold and tumor evolution. Curr Opin Cell Biol 2010; 22: 697-706; PMID: 20822891; http://dx. doi. org/10. 1016/j. ceb. 2010. 08. 015.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 697-706
    • Egeblad, M.1    Rasch, M.G.2    Weaver, V.M.3
  • 77
    • 11144228263 scopus 로고    scopus 로고
    • Type V collagen controls the initiation of collagen fibril assembly
    • PMID: 15383546
    • Wenstrup RJ, Florer JB, Brunskill EW, Bell SM, Chervoneva I, Birk DE. Type V collagen controls the initiation of collagen fibril assembly. J Biol Chem 2004; 279: 53331-7; PMID: 15383546; http://dx. doi. org/10. 1074/jbc. M409622200.
    • (2004) J Biol Chem , vol.279 , pp. 53331-53337
    • Wenstrup, R.J.1    Florer, J.B.2    Brunskill, E.W.3    Bell, S.M.4    Chervoneva, I.5    Birk, D.E.6
  • 78
    • 44749093210 scopus 로고    scopus 로고
    • Heparanase involvement in physiology and disease
    • PMID: 18425416
    • Nasser NJ. Heparanase involvement in physiology and disease. Cell Mol Life Sci 2008; 65: 1706-15; PMID: 18425416; http://dx. doi. org/10. 1007/s00018-008-7584-6.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 1706-1715
    • Nasser, N.J.1
  • 79
    • 77950561915 scopus 로고    scopus 로고
    • CD44, a therapeutic target for metastasising tumours
    • PMID: 20303742
    • Orian-Rousseau V. CD44, a therapeutic target for metastasising tumours. Eur J Cancer 2010; 46: 1271-7; PMID: 20303742; http://dx. doi. org/10. 1016/j. ejca. 2010. 02. 024.
    • (2010) Eur J Cancer , vol.46 , pp. 1271-1277
    • Orian-Rousseau, V.1
  • 80
    • 0242509224 scopus 로고    scopus 로고
    • ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix
    • PMID: 14610060
    • Wozniak MA, Desai R, Solski PA, Der CJ, Keely PJ. ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. J Cell Biol 2003; 163: 583-95; PMID: 14610060; http://dx. doi. org/10. 1083/jcb. 200305010.
    • (2003) J Cell Biol , vol.163 , pp. 583-595
    • Wozniak, M.A.1    Desai, R.2    Solski, P.A.3    Der, C.J.4    Keely, P.J.5
  • 82
    • 72049098196 scopus 로고    scopus 로고
    • Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage
    • PMID: 19826415
    • Provenzano PP, Inman DR, Eliceiri KW, Keely PJ. Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage. Oncogene 2009; 28: 4326-43; PMID: 19826415; http://dx. doi. org/10. 1038/onc. 2009. 299.
    • (2009) Oncogene , vol.28 , pp. 4326-4343
    • Provenzano, P.P.1    Inman, D.R.2    Eliceiri, K.W.3    Keely, P.J.4
  • 83
    • 0017654607 scopus 로고
    • Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes
    • PMID: 559643
    • Emerman JT, Pitelka DR. Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes. In Vitro 1977; 13: 316-28; PMID: 559643; http://dx. doi. org/10. 1007/BF02616178.
    • (1977) In Vitro , vol.13 , pp. 316-328
    • Emerman, J.T.1    Pitelka, D.R.2
  • 85
    • 0033032317 scopus 로고    scopus 로고
    • Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
    • PMID: 10371505
    • Sethi T, Rintoul RC, Moore SM, MacKinnon AC, Salter D, Choo C, Chilvers ER, Dransfield I, Donnelly SC, Strieter R., et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med 1999; 5: 662-8; PMID: 10371505; http://dx. doi. org/10. 1038/9511.
    • (1999) Nat Med , vol.5 , pp. 662-668
    • Sethi, T.1    Rintoul, R.C.2    Moore, S.M.3    McKinnon, A.C.4    Salter, D.5    Choo, C.6    Chilvers, E.R.7    Dransfield, I.8    Donnelly, S.C.9    Strieter, R.10
  • 87
    • 0035863471 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity
    • PMID: 11212252
    • Mitsiades N, Yu WH, Poulaki V, Tsokos M, Stamenkovic I. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer Res 2001; 61: 577-81; PMID: 11212252.
    • (2001) Cancer Res , vol.61 , pp. 577-581
    • Mitsiades, N.1    Yu, W.H.2    Poulaki, V.3    Tsokos, M.4    Stamenkovic, I.5
  • 88
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • PMID: 11990853
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002; 2: 161-74; PMID: 11990853; http://dx. doi. org/10. 1038/nrc745.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 89
    • 70749159697 scopus 로고    scopus 로고
    • A stiff blow from the stroma: Collagen crosslinking drives tumor progression
    • PMID: 19962663
    • Ng MR, Brugge JS. A stiff blow from the stroma: collagen crosslinking drives tumor progression. Cancer Cell 2009; 16: 455-7; PMID: 19962663; http://dx. doi. org/10. 1016/j. ccr. 2009. 11. 013.
    • (2009) Cancer Cell , vol.16 , pp. 455-457
    • Ng, M.R.1    Brugge, J.S.2
  • 91
    • 58849126879 scopus 로고    scopus 로고
    • Three-dimensional context regulation of metastasis
    • PMID: 18814043
    • Erler JT, Weaver VM. Three-dimensional context regulation of metastasis. Clin Exp Metastasis 2009; 26: 35-49; PMID: 18814043; http://dx. doi. org/10. 1007/s10585-008-9209-8.
    • (2009) Clin Exp Metastasis , vol.26 , pp. 35-49
    • Erler, J.T.1    Weaver, V.M.2
  • 93
    • 29244436384 scopus 로고    scopus 로고
    • Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism
    • PMID: 16357151
    • Payne SL, Fogelgren B, Hess AR, Seftor EA, Wiley EL, Fong SF, Csiszar K, Hendrix MJ, Kirschmann DA. Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. Cancer Res 2005; 65: 11429-36; PMID: 16357151; http://dx. doi. org/10. 1158/0008-5472. CAN-05-1274.
    • (2005) Cancer Res , vol.65 , pp. 11429-11436
    • Payne, S.L.1    Fogelgren, B.2    Hess, A.R.3    Seftor, E.A.4    Wiley, E.L.5    Fong, S.F.6    Csiszar, K.7    Hendrix, M.J.8    Kirschmann, D.A.9
  • 95
    • 33846782878 scopus 로고    scopus 로고
    • Collagen reorganization at the tumor-stromal interface facilitates local invasion
    • PMID: 17190588
    • Provenzano PP, Eliceiri KW, Campbell JM, Inman DR, White JG, Keely PJ. Collagen reorganization at the tumor-stromal interface facilitates local invasion. BMC Med 2006; 4: 38; PMID: 17190588; http://dx. doi. org/10. 1186/1741-7015-4-38.
    • (2006) BMC Med , vol.4 , pp. 38
    • Provenzano, P.P.1    Eliceiri, K.W.2    Campbell, J.M.3    Inman, D.R.4    White, J.G.5    Keely, P.J.6
  • 96
    • 33845354896 scopus 로고    scopus 로고
    • Macrophages promote collagen fibrillogenesis around terminal end buds of the developing mammary gland
    • PMID: 17029292
    • Ingman WV, Wyckoff J, Gouon-Evans V, Condeelis J, Pollard JW. Macrophages promote collagen fibrillogenesis around terminal end buds of the developing mammary gland. Dev Dyn 2006; 235: 3222-9; PMID: 17029292; http://dx. doi. org/10. 1002/dvdy. 20972.
    • (2006) Dev Dyn , vol.235 , pp. 3222-3229
    • Ingman, W.V.1    Wyckoff, J.2    Gouon-Evans, V.3    Condeelis, J.4    Pollard, J.W.5
  • 97
    • 0035495401 scopus 로고    scopus 로고
    • Putting tumours in context
    • PMID: 11900251
    • Bissell MJ, Radisky D. Putting tumours in context. Nat Rev Cancer 2001; 1: 46-54; PMID: 11900251; http://dx. doi. org/10. 1038/35094059.
    • (2001) Nat Rev Cancer , vol.1 , pp. 46-54
    • Bissell, M.J.1    Radisky, D.2
  • 98
    • 79952340427 scopus 로고    scopus 로고
    • Remodeling and homeostasis of the extracellular matrix: Implications for fibrotic diseases and cancer
    • PMID: 21324931
    • Cox TR, Erler JT. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Models Mechanisms 2011; 4: 165-78; PMID: 21324931; http://dx. doi. org/10. 1242/dmm. 004077.
    • (2011) Dis Models Mechanisms , vol.4 , pp. 165-178
    • Cox, T.R.1    Erler, J.T.2


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