Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway

Islets

Volumn 7, Issue 1, 2015, Pages

  Hobson, Amanda ^a   Draney, Carrie ^a   Stratford, Andrew ^a   Becker, Thomas C ^b   Lu, Danhong ^b   Arlotto, Michelle ^b   Tessem, Jeffery S ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AURKA; Cell cycle; Islet; Nkx6.1; P53; Proliferation

Indexed keywords

AURORA A KINASE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BROXURIDINE; CYCLIN A2; CYCLIN B1; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4; HISTONE H2A; HISTONE H3; INHIBITOR OF DIFFERENTIATION 3; MYOD PROTEIN; NUCLEAR RECEPTOR NR4A3; NUCLEAR RECEPTOR NUR77; PROTEIN P53; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NKX6.1; AURKA PROTEIN, RAT; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; NERVE PROTEIN; NKX6A PROTEIN, RAT; NR4A1 PROTEIN, RAT; NR4A3 PROTEIN, RAT; RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA REPLICATION; FEMALE; FLOW CYTOMETRY; HISTOLOGY; HISTONE PHOSPHORYLATION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INSULIN RELEASE; MALE; MITOSIS; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; COMPARATIVE STUDY; GENETIC TRANSDUCTION; GENETICS; IN VITRO STUDY; METABOLISM; PROCEDURES; TUMOR SUPPRESSOR GENE;

ANIMALS; AURORA KINASE A; CELL PROLIFERATION; DNA-BINDING PROTEINS; GENES, P53; HOMEODOMAIN PROTEINS; IN VITRO TECHNIQUES; INSULIN-SECRETING CELLS; NERVE TISSUE PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; RATS; RNA; TRANSDUCTION, GENETIC;

EID: 84944710775     PISSN: 19382014     EISSN: 19382022     Source Type: Journal    
DOI: 10.1080/19382014.2015.1027854     Document Type: Article

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