Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation

Immunity

Volumn 43, Issue 4, 2015, Pages 715-726

  Cao, Zhifang ^a   Conway, Kara L ^a,b   Heath, Robert J ^a,b   Rush, Jason S ^b   Leshchiner, Elizaveta S ^b   Ramirez Ortiz, Zaida G ^a   Nedelsky, Natalia B ^a   Huang, Hailiang ^a,b   Ng, Aylwin ^a,b   Gardet, Agnès ^a   Cheng, Shih Chin ^c   Shamji, Alykhan F ^b   Rioux, John D ^d   Wijmenga, Cisca ^e   Netea, Mihai G ^c   Means, Terry K ^a   Daly, Mark J ^a,b   Xavier, Ramnik J ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d MONTREAL HEART INSTITUTE   (Canada)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CARD9 PROTEIN; CYTOKINE; LECTIN RECEPTOR; PROTEIN VARIANT; TRIM62 PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; ANGIOTENSIN RECEPTOR; CARD9 PROTEIN, HUMAN; CARD9 PROTEIN, MOUSE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; DEAR1 PROTEIN, MOUSE; ENDOTHELIN RECEPTOR; HYBRID PROTEIN; IMMUNOLOGICAL ADJUVANT; ISOPROTEIN; TRIM62 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANDIDA ALBICANS; CARBOXY TERMINAL SEQUENCE; CARD9 GENE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FUNGUS IMMUNITY; GENE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; INFECTION SENSITIVITY; INFLAMMATORY BOWEL DISEASE; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRIM62 GENE; UBIQUITINATION; 129 MOUSE; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; CHEMISTRY; COLITIS; DEFICIENCY; DENDRITIC CELL; DOMINANT GENE; GENETIC PREDISPOSITION; GENETICS; GERMFREE ANIMAL; HEK293 CELL LINE; HELA CELL LINE; IMMUNOLOGY; INVASIVE CANDIDIASIS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CANDIDIASIS, INVASIVE; CARD SIGNALING ADAPTOR PROTEINS; COLITIS; CYTOKINES; DENDRITIC CELLS; GENES, DOMINANT; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HELA CELLS; HUMANS; INFLAMMATORY BOWEL DISEASES; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; PROTEIN INTERACTION MAPPING; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANGIOTENSIN; RECEPTORS, ENDOTHELIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84944684568     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.10.005     Document Type: Article

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