Chronic Candida albicans Meningitis in a 4-Year-Old Girl with a Homozygous Mutation in the CARD9 Gene (Q295X)

Pediatric Infectious Disease Journal

Volumn 34, Issue 9, 2015, Pages 999-1002

  Herbst, Martin ^a   Gazendam, Roel ^b   Reimnitz, Denise ^c   Sawalle Belohradsky, Julie ^d   Groll, Andreas ^e   Schlegel, Paul Gerhardt ^a   Belohradsky, Bernd ^d   Renner, Ellen ^d   Klepper, Jörg ^c   Grimbacher, Bodo ^f   Kuijpers, Taco ^b,g   Liese, Johannes ^a,h  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b SANQUIN RESEARCH   (Netherlands)

^c Aschaffenburg Hospital   (Germany)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^e UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^f UNIVERSITY OF FREIBURG   (Germany)

^g UNIVERSITY OF AMSTERDAM   (Netherlands)

^h UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

Candida albicans meningitis; caspase recruitment domain containing protein 9 deficiency; chronic mucocutaneous candidiasis; impaired neutrophil killing; primary immunodeficiency

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; ANTIPARASITIC AGENT; FLUCONAZOLE; FLUCYTOSINE; GENOMIC DNA; GLUCOSE; IMMUNOGLOBULIN E; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTIC ACID; OPSONIN; REACTIVE OXYGEN METABOLITE; VORICONAZOLE; ANTIFUNGAL AGENT; CARD9 PROTEIN, HUMAN; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN;

ARTICLE; ASCARIASIS; B LYMPHOCYTE; CANDIDA ALBICANS; CANDIDA MENINGITIS; CANDIDIASIS; CASE REPORT; CASPASE RECRUITMENT DOMAIN 9 GENE; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHILD; CONSANGUINEOUS MARRIAGE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; DISEASE COURSE; DRUG DOSE ESCALATION; DRUG MEGADOSE; ENZYME DEFICIENCY; EOSINOPHILIA; FECES ANALYSIS; FEMALE; FEVER; FUNGUS CULTURE; GENE; GENETIC ANALYSIS; GENETIC PREDISPOSITION; HEADACHE; HUMAN; HUMAN CELL; IRON DEFICIENCY ANEMIA; LEUKOCYTOSIS; MAGNETIC RESONANCE ANGIOGRAPHY; MUCOCUTANEOUS CANDIDIASIS; NEUROIMAGING; NEUTROPHIL; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL BLOOD MONONUCLEAR CELL; PLEOCYTOSIS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE; THRUSH; TREATMENT RESPONSE; COMBINATION DRUG THERAPY; DEFICIENCY; GENETICS; HOMOZYGOTE; IMMUNOLOGY; ISOLATION AND PURIFICATION; MENINGITIS, FUNGAL; MISSENSE MUTATION; TREATMENT OUTCOME; TURKEY;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; CARD SIGNALING ADAPTOR PROTEINS; CHILD, PRESCHOOL; DRUG THERAPY, COMBINATION; FEMALE; HOMOZYGOTE; HUMANS; MENINGITIS, FUNGAL; MUTATION, MISSENSE; TREATMENT OUTCOME; TURKEY;

EID: 84940036759     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0000000000000736     Document Type: Article

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