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Volumn 35, Issue 21, 2015, Pages 3604-3621

Loss of ADAM17-mediated tumor necrosis factor alpha signaling in intestinal cells attenuates mucosal atrophy in a mouse model of parenteral nutrition

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; ADAM17 PROTEIN; CASPASE 3; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN BAX; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ADAM17 PROTEIN, HUMAN; ADAM17 PROTEIN, MOUSE; CYTOKINE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

EID: 84944615587     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00143-15     Document Type: Article
Times cited : (22)

References (63)
  • 1
    • 84897919842 scopus 로고    scopus 로고
    • Intestinal epithelial cell apoptosis and loss of barrier function in the setting of altered microbiota with enteral nutrient deprivation
    • Demehri FR, Barrett M, Ralls MW, Miyasaka EA, Feng Y, Teitelbaum DH. 2013. Intestinal epithelial cell apoptosis and loss of barrier function in the setting of altered microbiota with enteral nutrient deprivation. Front Cell Infect Microbiol 3:105. http://dx.doi.org/10.3389/fcimb.2013.00105.
    • (2013) Front Cell Infect Microbiol , vol.3 , pp. 105
    • Demehri, F.R.1    Barrett, M.2    Ralls, M.W.3    Miyasaka, E.A.4    Feng, Y.5    Teitelbaum, D.H.6
  • 3
    • 84855304103 scopus 로고    scopus 로고
    • Epidermal growth factor/TNF-alpha transactivation modulates epithelial cell proliferation and apoptosis in a mouse model of parenteral nutrition
    • Feng Y, Teitelbaum DH. 2012. Epidermal growth factor/TNF-alpha transactivation modulates epithelial cell proliferation and apoptosis in a mouse model of parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 302:G236-G249. http://dx.doi.org/10.1152/ajpgi.00142.2011.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.302 , pp. G236-G249
    • Feng, Y.1    Teitelbaum, D.H.2
  • 4
    • 84880986819 scopus 로고    scopus 로고
    • Tumour necrosis factor-induced loss of intestinal barrier function requires TNFR1 and TNFR2 signaling in a mouse model of total parenteral nutrition
    • Feng Y, Teitelbaum DH. 2013. Tumour necrosis factor-induced loss of intestinal barrier function requires TNFR1 and TNFR2 signaling in a mouse model of total parenteral nutrition. J Physiol 591:3709-3723. http://dx.doi.org/10.1113/jphysiol.2013.253518.
    • (2013) J Physiol , vol.591 , pp. 3709-3723
    • Feng, Y.1    Teitelbaum, D.H.2
  • 5
    • 79960923986 scopus 로고    scopus 로고
    • ADAM17: a molecular switch to control inflammation and tissue regeneration
    • Scheller J, Chalaris A, Garbers C, Rose-John S. 2011. ADAM17: a molecular switch to control inflammation and tissue regeneration. Trends Immunol 32:380-387. http://dx.doi.org/10.1016/j.it.2011.05.005.
    • (2011) Trends Immunol , vol.32 , pp. 380-387
    • Scheller, J.1    Chalaris, A.2    Garbers, C.3    Rose-John, S.4
  • 6
    • 84866487100 scopus 로고    scopus 로고
    • Ectodomain shedding and ADAMs in development
    • Weber S, Saftig P. 2012. Ectodomain shedding and ADAMs in development. Development 139:3693-3709. http://dx.doi.org/10.1242/dev.076398.
    • (2012) Development , vol.139 , pp. 3693-3709
    • Weber, S.1    Saftig, P.2
  • 9
    • 34347391898 scopus 로고    scopus 로고
    • Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages
    • Bell JH, Herrera AH, Li Y, Walcheck B. 2007. Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages. J Leukoc Biol 82:173-176. http://dx.doi.org/10.1189/jlb.0307193.
    • (2007) J Leukoc Biol , vol.82 , pp. 173-176
    • Bell, J.H.1    Herrera, A.H.2    Li, Y.3    Walcheck, B.4
  • 10
    • 33947629847 scopus 로고    scopus 로고
    • Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development
    • Li N, Boyd K, Dempsey PJ, Vignali DA. 2007. Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development. J Immunol 178:4214-4221. http://dx.doi.org/10.4049/jimmunol.178.7.4214.
    • (2007) J Immunol , vol.178 , pp. 4214-4221
    • Li, N.1    Boyd, K.2    Dempsey, P.J.3    Vignali, D.A.4
  • 12
    • 84899117057 scopus 로고    scopus 로고
    • Cellular sources of pathogenic and protective TNF and experimental strategies based on utilization of TNF humanized mice
    • Winsauer C, Kruglov AA, Chashchina AA, Drutskaya MS, Nedospasov SA. 2014. Cellular sources of pathogenic and protective TNF and experimental strategies based on utilization of TNF humanized mice. Cytokine Growth Factor Rev 25:115-123. http://dx.doi.org/10.1016/j.cytogfr.2013.12.005.
    • (2014) Cytokine Growth Factor Rev , vol.25 , pp. 115-123
    • Winsauer, C.1    Kruglov, A.A.2    Chashchina, A.A.3    Drutskaya, M.S.4    Nedospasov, S.A.5
  • 14
    • 0029045856 scopus 로고
    • Strain-dependent epithelial defects in mice lacking the EGF receptor
    • Sibilia M, Wagner EF. 1995. Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269:234-238. http://dx.doi.org/10.1126/science.7618085.
    • (1995) Science , vol.269 , pp. 234-238
    • Sibilia, M.1    Wagner, E.F.2
  • 16
    • 0027315183 scopus 로고
    • Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation
    • Mann GB, Fowler KJ, Gabriel A, Nice EC, Williams RL, Dunn AR. 1993. Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 73:249-261. http://dx.doi.org/10.1016/0092-8674(93)90227-H.
    • (1993) Cell , vol.73 , pp. 249-261
    • Mann, G.B.1    Fowler, K.J.2    Gabriel, A.3    Nice, E.C.4    Williams, R.L.5    Dunn, A.R.6
  • 17
    • 26244464287 scopus 로고    scopus 로고
    • Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin
    • Sternlicht MD, Sunnarborg SW, Kouros-Mehr H, Yu Y, Lee DC, Werb Z. 2005. Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin. Development 132:3923-3933. http://dx.doi.org/10.1242/dev.01966.
    • (2005) Development , vol.132 , pp. 3923-3933
    • Sternlicht, M.D.1    Sunnarborg, S.W.2    Kouros-Mehr, H.3    Yu, Y.4    Lee, D.C.5    Werb, Z.6
  • 18
    • 0037507267 scopus 로고    scopus 로고
    • Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
    • Jackson LF, Qiu TH, Sunnarborg SW, Chang A, Zhang C, Patterson C, Lee DC. 2003. Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling. EMBO J 22:2704-2716. http://dx.doi.org/10.1093/emboj/cdg264.
    • (2003) EMBO J , vol.22 , pp. 2704-2716
    • Jackson, L.F.1    Qiu, T.H.2    Sunnarborg, S.W.3    Chang, A.4    Zhang, C.5    Patterson, C.6    Lee, D.C.7
  • 22
    • 84856013483 scopus 로고    scopus 로고
    • Inflammatory bowel disease and ADAM17 deletion
    • Brandl K, Tomisato W, Beutler B. 2012. Inflammatory bowel disease and ADAM17 deletion. N Engl J Med 366:190. http://dx.doi.org/10.1056/NEJMc1113373.
    • (2012) N Engl J Med , vol.366 , pp. 190
    • Brandl, K.1    Tomisato, W.2    Beutler, B.3
  • 24
    • 59849113041 scopus 로고    scopus 로고
    • The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF
    • Frey MR, Edelblum KL, Mullane MT, Liang D, Polk DB. 2009. The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF. Gastroenterology 136:217-226. http://dx.doi.org/10.1053/j.gastro.2008.09.023.
    • (2009) Gastroenterology , vol.136 , pp. 217-226
    • Frey, M.R.1    Edelblum, K.L.2    Mullane, M.T.3    Liang, D.4    Polk, D.B.5
  • 26
    • 84863248698 scopus 로고    scopus 로고
    • ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival
    • Zhang Y, Dube PE, Washington MK, Yan F, Polk DB. 2012. ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival. Lab Invest 92:437-450. http://dx.doi.org/10.1038/labinvest.2011.192.
    • (2012) Lab Invest , vol.92 , pp. 437-450
    • Zhang, Y.1    Dube, P.E.2    Washington, M.K.3    Yan, F.4    Polk, D.B.5
  • 28
    • 79960663856 scopus 로고    scopus 로고
    • Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites
    • Tang J, Zarbock A, Gomez I, Wilson CL, Lefort CT, Stadtmann A, Bell B, Huang LC, Ley K, Raines EW. 2011. Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites. Blood 118:786-794. http://dx.doi.org/10.1182/blood-2010-11-321406.
    • (2011) Blood , vol.118 , pp. 786-794
    • Tang, J.1    Zarbock, A.2    Gomez, I.3    Wilson, C.L.4    Lefort, C.T.5    Stadtmann, A.6    Bell, B.7    Huang, L.C.8    Ley, K.9    Raines, E.W.10
  • 29
    • 84875883763 scopus 로고    scopus 로고
    • Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults
    • Wilson CL, Gough PJ, Chang CA, Chan CK, Frey JM, Liu Y, Braun KR, Chin MT, Wight TN, Raines EW. 2013. Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mech Dev 130:272-289. http://dx.doi.org/10.1016/j.mod.2013.01.001.
    • (2013) Mech Dev , vol.130 , pp. 272-289
    • Wilson, C.L.1    Gough, P.J.2    Chang, C.A.3    Chan, C.K.4    Frey, J.M.5    Liu, Y.6    Braun, K.R.7    Chin, M.T.8    Wight, T.N.9    Raines, E.W.10
  • 30
    • 84886909059 scopus 로고    scopus 로고
    • A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor
    • Yan F, Liu L, Dempsey PJ, Tsai YH, Raines EW, Wilson CL, Cao H, Cao Z, Liu L, Polk DB. 2013. A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor. J Biol Chem 288:30742-30751. http://dx.doi.org/10.1074/jbc.M113.492397.
    • (2013) J Biol Chem , vol.288 , pp. 30742-30751
    • Yan, F.1    Liu, L.2    Dempsey, P.J.3    Tsai, Y.H.4    Raines, E.W.5    Wilson, C.L.6    Cao, H.7    Cao, Z.8    Liu, L.9    Polk, D.B.10
  • 31
    • 48249115700 scopus 로고    scopus 로고
    • Specific overexpression of IL-7 in the intestinal mucosa: the role in intestinal intraepithelial lymphocyte development
    • Yang H, Madison B, Gumucio DL, Teitelbaum DH. 2008. Specific overexpression of IL-7 in the intestinal mucosa: the role in intestinal intraepithelial lymphocyte development. Am J Physiol Gastrointest Liver Physiol 294:G1421-G1430. http://dx.doi.org/10.1152/ajpgi.00060.2008.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , pp. G1421-G1430
    • Yang, H.1    Madison, B.2    Gumucio, D.L.3    Teitelbaum, D.H.4
  • 32
    • 67649970912 scopus 로고    scopus 로고
    • The bone morphogenetic protein signaling pathway is upregulated in a mouse model of total parenteral nutrition
    • Zhang C, Feng Y, Yang H, Koga H, Teitelbaum DH. 2009. The bone morphogenetic protein signaling pathway is upregulated in a mouse model of total parenteral nutrition. J Nutr 139:1315-1321. http://dx.doi.org/10.3945/jn.108.096669.
    • (2009) J Nutr , vol.139 , pp. 1315-1321
    • Zhang, C.1    Feng, Y.2    Yang, H.3    Koga, H.4    Teitelbaum, D.H.5
  • 34
    • 47349097005 scopus 로고    scopus 로고
    • Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis
    • Fries W, Muja C, Crisafulli C, Costantino G, Longo G, Cuzzocrea S, Mazzon E. 2008. Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis. Int J Med Sci 5:169-180.
    • (2008) Int J Med Sci , vol.5 , pp. 169-180
    • Fries, W.1    Muja, C.2    Crisafulli, C.3    Costantino, G.4    Longo, G.5    Cuzzocrea, S.6    Mazzon, E.7
  • 35
    • 79952076124 scopus 로고    scopus 로고
    • Anti-TNF therapy using etanercept suppresses degenerative and inflammatory changes in skeletal muscle of older SJL/J mice
    • Nemoto H, Konno S, Sugimoto H, Nakazora H, Nomoto N, Murata M, Kitazono H, Fujioka T. 2011. Anti-TNF therapy using etanercept suppresses degenerative and inflammatory changes in skeletal muscle of older SJL/J mice. Exp Mol Pathol 90:264-270. http://dx.doi.org/10.1016/j.yexmp.2011.02.003.
    • (2011) Exp Mol Pathol , vol.90 , pp. 264-270
    • Nemoto, H.1    Konno, S.2    Sugimoto, H.3    Nakazora, H.4    Nomoto, N.5    Murata, M.6    Kitazono, H.7    Fujioka, T.8
  • 38
    • 77952712241 scopus 로고    scopus 로고
    • Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy
    • Feng Y, McDunn JE, Teitelbaum DH. 2010. Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy. Am J Physiol Gastrointest Liver Physiol 298:G833-G841. http://dx.doi.org/10.1152/ajpgi.00030.2010.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298 , pp. G833-G841
    • Feng, Y.1    McDunn, J.E.2    Teitelbaum, D.H.3
  • 39
    • 0036320133 scopus 로고    scopus 로고
    • Interferon-gamma expression by intraepithelial lymphocytes results in a loss of epithelial barrier function in a mouse model of total parenteral nutrition
    • Yang H, Kiristioglu I, Fan Y, Forbush B, Bishop DK, Antony PA, Zhou H, Teitelbaum DH. 2002. Interferon-gamma expression by intraepithelial lymphocytes results in a loss of epithelial barrier function in a mouse model of total parenteral nutrition. Ann Surg 236:226-234. http://dx.doi.org/10.1097/00000658-200208000-00011.
    • (2002) Ann Surg , vol.236 , pp. 226-234
    • Yang, H.1    Kiristioglu, I.2    Fan, Y.3    Forbush, B.4    Bishop, D.K.5    Antony, P.A.6    Zhou, H.7    Teitelbaum, D.H.8
  • 40
    • 0037377449 scopus 로고    scopus 로고
    • Intraepithelial lymphocytederived interferon-gamma evokes enterocyte apoptosis with parenteral nutrition in mice
    • Yang H, Fan Y, Teitelbaum DH. 2003. Intraepithelial lymphocytederived interferon-gamma evokes enterocyte apoptosis with parenteral nutrition in mice. Am J Physiol Gastrointest Liver Physiol 284:G629-G637. http://dx.doi.org/10.1152/ajpgi.00290.2002.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284 , pp. G629-G637
    • Yang, H.1    Fan, Y.2    Teitelbaum, D.H.3
  • 41
    • 38649092417 scopus 로고    scopus 로고
    • Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition
    • Sun X, Yang H, Nose K, Nose S, Haxhija EQ, Koga H, Feng Y, Teitelbaum DH. 2008. Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 294:G139-G147.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , pp. G139-G147
    • Sun, X.1    Yang, H.2    Nose, K.3    Nose, S.4    Haxhija, E.Q.5    Koga, H.6    Feng, Y.7    Teitelbaum, D.H.8
  • 44
    • 84866234496 scopus 로고    scopus 로고
    • Enterocyte expression of epidermal growth factor receptor is not required for intestinal adaptation in response to massive small bowel resection
    • Rowland KJ, McMellen ME, Wakeman D, Wandu WS, Erwin CR, Warner BW. 2012. Enterocyte expression of epidermal growth factor receptor is not required for intestinal adaptation in response to massive small bowel resection. J Pediatr Surg 47:1748-1753. http://dx.doi.org/10.1016/j.jpedsurg.2012.03.089.
    • (2012) J Pediatr Surg , vol.47 , pp. 1748-1753
    • Rowland, K.J.1    McMellen, M.E.2    Wakeman, D.3    Wandu, W.S.4    Erwin, C.R.5    Warner, B.W.6
  • 45
    • 79957907960 scopus 로고    scopus 로고
    • Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism
    • Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Jr, Wilson KT, Polk DB. 2011. Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. J Clin Invest 121:2242-2253. http://dx.doi.org/10.1172/JCI44031.
    • (2011) J Clin Invest , vol.121 , pp. 2242-2253
    • Yan, F.1    Cao, H.2    Cover, T.L.3    Washington, M.K.4    Shi, Y.5    Liu, L.6    Chaturvedi, R.7    Peek, R.M.8    Wilson, K.T.9    Polk, D.B.10
  • 46
    • 44749088915 scopus 로고    scopus 로고
    • Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: mouse models
    • Kruglov AA, Kuchmiy A, Grivennikov SI, Tumanov AV, Kuprash DV, Nedospasov SA. 2008. Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: mouse models. Cytokine Growth Factor Rev 19:231-244. http://dx.doi.org/10.1016/j.cytogfr.2008.04.010.
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 231-244
    • Kruglov, A.A.1    Kuchmiy, A.2    Grivennikov, S.I.3    Tumanov, A.V.4    Kuprash, D.V.5    Nedospasov, S.A.6
  • 48
    • 0031596074 scopus 로고    scopus 로고
    • The EGF\EGF-receptor axis modulates enterocyte apoptosis during intestinal adaptation
    • Helmrath MA, Shin CE, Erwin CR, Warner BW. 1998. The EGF\EGF-receptor axis modulates enterocyte apoptosis during intestinal adaptation. J Surg Res 77:17-22. http://dx.doi.org/10.1006/jsre.1998.5362.
    • (1998) J Surg Res , vol.77 , pp. 17-22
    • Helmrath, M.A.1    Shin, C.E.2    Erwin, C.R.3    Warner, B.W.4
  • 49
    • 78650150602 scopus 로고    scopus 로고
    • Intestinal growth factors: potential use in the treatment of inflammatory bowel disease and their role in mucosal healing
    • Krishnan K, Arnone B, Buchman A. 2011. Intestinal growth factors: potential use in the treatment of inflammatory bowel disease and their role in mucosal healing. Inflamm Bowel Dis 17:410-422. http://dx.doi.org/10.1002/ibd.21316.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 410-422
    • Krishnan, K.1    Arnone, B.2    Buchman, A.3
  • 50
    • 0033639223 scopus 로고    scopus 로고
    • Mice harboring a defective epidermal growth factor receptor (waved-2) have an increased susceptibility to acute dextran sulfateinduced colitis
    • Egger B, Buchler MW, Lakshmanan J, Moore P, Eysselein VE. 2000. Mice harboring a defective epidermal growth factor receptor (waved-2) have an increased susceptibility to acute dextran sulfateinduced colitis. Scand J Gastroenterol 35:1181-1187. http://dx.doi.org/10.1080/003655200750056664.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 1181-1187
    • Egger, B.1    Buchler, M.W.2    Lakshmanan, J.3    Moore, P.4    Eysselein, V.E.5
  • 52
    • 85030566169 scopus 로고    scopus 로고
    • Intestinal cell responses in different injury/regeneration models are differentially dependent on ADAM17
    • Tsai Y-H, Feng Y, Wade A, Teitelbaum D, Dempsey P. 2012. Intestinal cell responses in different injury/regeneration models are differentially dependent on ADAM17. Gastroenterology 142:S-61.
    • (2012) Gastroenterology , vol.142 , pp. S-61
    • Tsai, Y.-H.1    Feng, Y.2    Wade, A.3    Teitelbaum, D.4    Dempsey, P.5
  • 56
    • 33845685698 scopus 로고    scopus 로고
    • p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration
    • Frey MR, Dise RS, Edelblum KL, Polk DB. 2006. p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. EMBO J 25:5683-5692. http://dx.doi.org/10.1038/sj.emboj.7601457.
    • (2006) EMBO J , vol.25 , pp. 5683-5692
    • Frey, M.R.1    Dise, R.S.2    Edelblum, K.L.3    Polk, D.B.4
  • 57
    • 52449109740 scopus 로고    scopus 로고
    • Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism
    • McElroy SJ, Frey MR, Yan F, Edelblum KL, Goettel JA, John S, Polk DB. 2008. Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism. Am J Physiol Gastrointest Liver Physiol 295:G285-G293. http://dx.doi.org/10.1152/ajpgi.00425.2007.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295 , pp. G285-G293
    • McElroy, S.J.1    Frey, M.R.2    Yan, F.3    Edelblum, K.L.4    Goettel, J.A.5    John, S.6    Polk, D.B.7
  • 58
    • 33748928434 scopus 로고    scopus 로고
    • p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy
    • Zwang Y, Yarden Y. 2006. p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy. EMBO J 25:4195-4206. http://dx.doi.org/10.1038/sj.emboj.7601297.
    • (2006) EMBO J , vol.25 , pp. 4195-4206
    • Zwang, Y.1    Yarden, Y.2
  • 59
    • 84964693347 scopus 로고    scopus 로고
    • Redeeming an old foe: protective as well as pathophysiological roles for tumor necrosis factor in inflammatory bowel disease
    • Dube P, Punit S, Polk DB. 2014. Redeeming an old foe: protective as well as pathophysiological roles for tumor necrosis factor in inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol 308: G161-G170. http://dx.doi.org/10.1152/ajpgi.00142.2014.
    • (2014) Am J Physiol Gastrointest Liver Physiol , vol.308 , pp. G161-G170
    • Dube, P.1    Punit, S.2    Polk, D.B.3
  • 60
    • 79955113861 scopus 로고    scopus 로고
    • Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology
    • Roulis M, Armaka M, Manoloukos M, Apostolaki M, Kollias G. 2011. Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology. Proc Natl Acad Sci U S A 108:5396-5401. http://dx.doi.org/10.1073/pnas.1007811108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 5396-5401
    • Roulis, M.1    Armaka, M.2    Manoloukos, M.3    Apostolaki, M.4    Kollias, G.5
  • 61
    • 0036303112 scopus 로고    scopus 로고
    • Intestinal epithelial cells as a source of inflammatory cytokines and chemokines
    • Stadnyk AW. 2002. Intestinal epithelial cells as a source of inflammatory cytokines and chemokines. Can J Gastroenterol 16:241-246.
    • (2002) Can J Gastroenterol , vol.16 , pp. 241-246
    • Stadnyk, A.W.1
  • 62
    • 84884390272 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice
    • Xue X, Ramakrishnan S, Anderson E, Taylor M, Zimmermann EM, Spence JR, Huang S, Greenson JK, Shah YM. 2013. Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice. Gastroenterology 145:831-841. http://dx.doi.org/10.1053/j.gastro.2013.07.010.
    • (2013) Gastroenterology , vol.145 , pp. 831-841
    • Xue, X.1    Ramakrishnan, S.2    Anderson, E.3    Taylor, M.4    Zimmermann, E.M.5    Spence, J.R.6    Huang, S.7    Greenson, J.K.8    Shah, Y.M.9
  • 63
    • 84904119437 scopus 로고    scopus 로고
    • Pleiotropic functions of TNF-alpha in the regulation of the intestinal epithelial response to inflammation
    • Leppkes M, Roulis M, Neurath MF, Kollias G, Becker C. 2014. Pleiotropic functions of TNF-alpha in the regulation of the intestinal epithelial response to inflammation. Int Immunol 26:509-515. http://dx.doi.org/10.1093/intimm/dxu051.
    • (2014) Int Immunol , vol.26 , pp. 509-515
    • Leppkes, M.1    Roulis, M.2    Neurath, M.F.3    Kollias, G.4    Becker, C.5


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