Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand- dependent terminal keratinocyte differentiation

Journal of Experimental Medicine

Volumn 209, Issue 6, 2012, Pages 1105-1119

  Franzke, Claus Werner ^a   Cobzaru, Cristina ^a   Triantafyllopoulou, Antigoni ^a   Löffek, Stefanie ^a   Horiuchi, Keisuke ^b   Threadgill, David W ^c   Kurz, Thomas ^d   van Rooijen, Nico ^e   Bruckner Tuderman, Leena ^a,d   Blobel, Carl P ^f,g  

^a UNIVERSITY OF FREIBURG   (Germany)

^b KEIO UNIVERSITY   (Japan)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF FREIBURG   (Germany)

^e VU UNIVERSITY AMSTERDAM   (Netherlands)

^f HOSPITAL FOR SPECIAL SURGERY   (United States)

^g WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; ADAM17 PROTEIN; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; INTERLEUKIN 36ALPHA; L SELECTIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; RECOMBINANT CYTOKINE; RECOMBINANT TRANSFORMING GROWTH FACTOR ALPHA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDERMIS; HOMEOSTASIS; IMMUNOCOMPETENT CELL; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKIN INFLAMMATION; SKIN WATER LOSS; UPREGULATION;

ADAM PROTEINS; ADMINISTRATION, TOPICAL; ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; DERMATITIS, ATOPIC; EPIDERMIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERLEUKIN-1; KERATINOCYTES; MACROPHAGES; MICE; MICE, MUTANT STRAINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SKIN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSGLUTAMINASES;

EID: 84864317357     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20112258     Document Type: Article

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