Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: A potential mechanism for the development of intestinal mucosal atrophy

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 298, Issue 6, 2010, Pages

  Feng, Yongjia ^a   McDunn, Jonathan E ^b   Teitelbaum, Daniel H ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Intestinal epithelial cell; Mammalian target of rapamycin; Proliferation

Indexed keywords

BETA CATENIN; ENZYME ACTIVATOR; GLYCOGEN SYNTHASE KINASE 3BETA; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; TCL1 PEPTIDE; TRANSACTIVATOR OF TRANSCRIPTION; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ATROPHY; C57BL 6 MOUSE; CANNULATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; DRUG ACTIVITY; ENZYME ACTIVITY; EPITHELIUM CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSAL ATROPHY; INTESTINE MOTILITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOTAL PARENTERAL NUTRITION; TRANSCRIPTION INITIATION;

ANIMALS; ATROPHY; BETA CATENIN; CELL PROLIFERATION; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; INTESTINAL MUCOSA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; PARENTERAL NUTRITION, TOTAL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS; TRANS-ACTIVATORS; WNT PROTEINS;

EID: 77952712241     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00030.2010     Document Type: Article

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