Therapeutic approaches of magnetic nanoparticles for the central nervous system

Drug Discovery Today

Volumn 20, Issue 10, 2015, Pages 1256-1264

  Dilnawaz, Fahima ^a   Sahoo, Sanjeeb Kumar ^a  

^a INSTITUTE OF LIFE SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FERUMOXYTOL; MAGNETIC NANOPARTICLE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; CENTRAL NERVOUS SYSTEM AGENTS; CONTRAST MEDIUM; DRUG CARRIER; MAGNETITE NANOPARTICLE;

ALZHEIMER DISEASE; BLOOD BRAIN BARRIER; CANCER THERAPY; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; DRUG ACCUMULATION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RETENTION; DRUG TRANSPORT; HUMAN; HUNTINGTON CHOREA; IN VITRO STUDY; INVASIVE PROCEDURE; MAGNETIC FIELD; MOLECULAR IMAGING; NANOTECHNOLOGY; NON INVASIVE PROCEDURE; NONHUMAN; PARKINSON DISEASE; REVIEW; ANIMAL; CENTRAL NERVOUS SYSTEM DISEASES; CHEMISTRY; DRUG DESIGN; METABOLISM; PROCEDURES; THERANOSTIC NANOMEDICINE;

ANIMALS; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM AGENTS; CENTRAL NERVOUS SYSTEM DISEASES; CONTRAST MEDIA; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; MAGNETITE NANOPARTICLES; NANOTECHNOLOGY; THERANOSTIC NANOMEDICINE;

EID: 84944441935     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2015.06.008     Document Type: Review

References (68)

1. L. Shah, and M. Amiji Nanotechnology for CNS delivery of bio-therapeutic agents Drug Deliv. Transl. Res. 3 2013 336 351
2. D. Begley Delivery of therapeutic agents to the central nervous system: the problems and the possibilities Pharmacol. Ther. 104 2004 29 45
3. Y. Chen, and et al. Modern methods for delivery of drugs across the blood-brain barrier Adv. Drug Deliv. Rev. 64 2012 640 665
4. S.C. McBain, and et al. Magnetic nanoparticles for gene and drug delivery Int. J. Nanomed. 3 2008 169 180
5. T.M. Barchet, and M. Amiji Challenges and opportunities in CNS delivery of therapeutics for neurodegenerative diseases Expert Opin. Drug Deliv. 6 2009 211 225
6. L.L. Rubin, and J.M. Staddon The cell biology of the blood-brain barrier Annu. Rev. Neurosci. 22 1999 11 28
7. I. Brasnjevic, and et al. Delivery of peptide and protein drugs over the blood-brain barrier Prog. Neurobiol. 87 2009 212 251
8. H. Potschka, and M.H. Luna-Munguia CNS transporters and drug delivery in epilepsy Curr. Pharm. Des. 20 2014 1534 1542
9. N.B. Chauhan Trafficking of intracerebroventricularly injected antisense oligonucleotides in the mouse brain Antisense Nucl. Acid Drug Dev. 12 2002 353 357
10. M. Westphal, and et al. Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial Acta Neurochir. 148 2006 269 275
11. A. Tsuji Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems NeuroRx 2 2005 54 62
12. L.L. Zou, and et al. Cell-penetrating peptide-mediated therapeutic molecule delivery into the central nervous system Curr. Neuropharmacol. 11 2013 197 208
13. S. Parveen, and et al. Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging Nanomedicine 8 2012 147 166
14. S.K. Sahoo, and et al. The present and future of nanotechnology in human health care Nanomedicine 3 2007 20 31
15. J. Kreuter Nanoparticulate systems for brain delivery of drugs Adv. Drug Deliv. Rev. 47 2001 65 81
16. S.M. Moghimi, and et al. Long-circulating and target-specific nanoparticles: theory to practice Pharmacol. Rev. 53 2001 283 318
17. J. Kreuter Drug delivery to the central nervous system by polymeric nanoparticles: what do we know? Adv. Drug Deliv. Rev. 71 2014 2 14
18. C. Alexiou, and et al. Delivery of superparamagnetic nanoparticles for local chemotherapy after intraarterial infusion and magnetic drug targeting Anticancer Res. 27 2007 2019 2022
19. K.J. Widder, and et al. Magnetically responsive microspheres and other carriers for the biophysical targeting of antitumor agents Adv. Pharmacol. Chemother. 16 1979 213 271
20. B. Chertok, and et al. Brain tumor targeting of magnetic nanoparticles for potential drug delivery: effect of administration route and magnetic field topography J. Control. Release 155 2011 393 399
21. M.Y. Hua, and et al. The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas Biomaterials 32 2011 516 527
22. S.D. Kong, and et al. Magnetic targeting of nanoparticles across the intact blood-brain barrier J. Control. Release 164 2012 49 57
23. D.C. Spencer, and R. Price Human immunodeficiency virus and the central nervous system Annu. Rev. Microbiol. 46 1992 655 693
24. Z.M. Saiyed, and et al. Magnetic nanoformulation of azidothymidine 5'-triphosphate for targeted delivery across the blood-brain barrier Int. J. Nanomed. 5 2010 157 166
25. F. Dilnawaz, and et al. The transport of non-surfactant based paclitaxel loaded magnetic nanoparticles across the blood brain barrier in a rat model Biomaterials 33 2012 2936 2951
26. F. Dilnawaz, and et al. Dual drug loaded superparamagnetic iron oxide nanoparticles for targeted cancer therapy Biomaterials 31 2010 3694 3706
27. G. Wang, and et al. One-step synthesis of water-dispersible ultra-small Fe3O4 nanoparticles as contrast agents for T1 and T2 magnetic resonance imaging Nanoscale 6 2014 2953 2963
28. S. Saito, and et al. Impact of surface coating and particle size on the uptake of small and ultrasmall superparamagnetic iron oxide nanoparticles by macrophages Int. J. Nanomed. 7 2012 5415
29. B.H. Kenzaoui, and et al. Evaluation of uptake and transport of cationic and anionic ultrasmall iron oxide nanoparticles by human colon cells Int. J. Nanomed. 7 2012 1275
30. H. Amiri, and et al. Protein corona affects the relaxivity and MRI contrast efficiency of magnetic nanoparticles Nanoscale 5 2013 8656 8665
31. H. Lee, and et al. Antibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imaging J. Am. Chem. Soc. 128 2006 7383 7389
32. 4 nanoparticles evaluated by in vitro cytotoxicity assays using normal, glia and breast cancer cells Nanotechnology 21 2010 075102
33. J. Gaasch, and et al. Brain iron toxicity: differential responses of astrocytes, neurons, and endothelial cells Neurochem. Res. 32 2007 1196 1208
34. Y. Anzai, and et al. Evaluation of neck and body metastases to nodes with ferumoxtran 10-enhanced MR imaging: phase III safety and efficacy study Radiology 228 2003 777 788
35. E. Neuwelt, and et al. Imaging of iron oxide nanoparticles by MR and light microscopy in patients with malignant brain tumours Neuropath. Appl. Neurobiol. 30 2004 456 471
36. C.G. Varallyay, and et al. High-resolution steady-state cerebral blood volume maps in patients with central nervous system neoplasms using ferumoxytol, a superparamagnetic iron oxide nanoparticle J. Cereb. Blood Flow Metab. 33 2013 780 786
37. S. Jain, and et al. RGD-anchored magnetic liposomes for monocytes/neutrophils-mediated brain targeting Int. J. Pharm. 261 2003 43 55
38. M.A. Shevtsov, and et al. Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma Neuro. Oncol. 16 2014 38 49
39. B. Chertok, and et al. Polyethyleneimine-modified iron oxide nanoparticles for brain tumor drug delivery using magnetic targeting and intra-carotid administration Biomaterials 31 2010 6317 6324
40. R. Deissler, and et al. Dependence of brownian and neel relaxation times on magnetic field strength Med. Phys. 41 2014 012301
41. R.K. Gilchrist, and et al. Selective inductive heating of lymph nodes Annal. Surg. 146 1957 596 606
42. A. Jordan, and et al. Magnetic fluid hyperthermia (MFH): cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles J. Magn. Magn. Mater. 201 1999 413 419
43. K. Maier-Hauff, and et al. Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: results of a feasibility study on patients with glioblastoma multiforme J. Neurooncol. 81 2007 53 60
44. K. Maier-Hauff, and et al. Efficacy and safety of intratumoral thermotherapy using magneticiron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme J. Neurooncol. 103 2011 317 324
45. M. Wankhede, and et al. Magnetic nanopar ticles:an emerging technology for malignant brain tumor imaging and therapy Exp. Rev. Clin. Pharmacol. 5 2012 173 186
46. D. Perl Neuropathology of Alzheimer's disease Mt. Sinai J. Med. 77 2010 32 42
47. Y.Z. Wadghiri, and et al. Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer's disease transgenic mice using magnetic resonance microimaging PLoS One 8 2013 e57097
48. E.K. Agyare, and et al. Engineering theranostic nanovehicles capable of targeting cerebrovascular amyloid deposits J. Control. Release 185 2014 121 129
49. H. Skaat, and et al. Antibody-conjugated, dual-modal, near-infrared fluorescent iron oxide nanoparticles for antiamyloidgenic activity and specific detection of amyloid-β fibrils Int. J. Nanomed. 8 2013 4063 4076
50. K.L. Viola, and et al. Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease Nat. Nanotechnol. 10 2015 91 98
51. J. Yang, and et al. Detection of amyloid plaques targeted by USPIO-Aβ1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging Neuroimage 55 2011 1600 1609
52. L.O. Sillerud, and et al. SPION-enhanced magnetic resonance imaging of Alzheimer's disease plaques in AβPP/PS-1 transgenic mouse brain J. Alzheimers Dis. 34 2013 349 365
53. N. Beckmann, and et al. Noninvasive magnetic resonance imaging detection of cerebral amyloid angiopathy-related microvascular alterations using superparamagnetic iron oxide particles in APP transgenic mouse models of Alzheimer's disease: application to passive Aβ immunotherapy J. Neurosci. 31 2011 1023 1031
54. M. Srikanthand, and J.A. Kessler Nanotechnology-novel therapeutics for CNS disorders Nat. Rev. Neurol. 8 2012 307 318
55. D. Weintraub, and et al. Parkinson's disease - Part 2: treatment of motor symptoms Am. J. Manag. Care 14 2008 S49 S58
56. M. Ahamed, and et al. Iron oxide nanoparticle-induced oxidative stress and genotoxicity in human skin epithelial and lung epithelial cell lines Curr. Pharm. Des. 19 2013 6681 6690
57. F. Walker Huntington's disease Lancet 369 2007 218 228
58. M.E. Bernardo, and et al. Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms Cancer Res. 67 2007 9142 9149
59. L. Moraes, and et al. Neuroprotective effects and magnetic resonance imaging of mesenchymal stem cells labeled with SPION in a rat model of Huntington's disease Stem Cell Res. 9 2012 143 155
60. A. Singh, and S.K. Sahoo Magnetic nanoparticles: a novel platform for cancer theranostics Drug Discov. Today 19 2014 474 481
61. S.H. Jalalian, and et al. Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivo Eur. J. Pharm. Sci. 50 2013 191 197
62. Z. Fan, and et al. Improving ultrasound gene transfection efficiency by controlling ultrasound excitation of microbubbles J. Control. Release 170 2013 401 413
63. H. Liu, and et al. Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain Proc. Natl. Acad. Sci. U. S. A. 107 2010 15205 15210
64. R. Mejías, and et al. Long term biotransformation and toxicity of dimercaptosuccinic acid-coated magnetic nanoparticles support their use in biomedical applications J. Control. Release 171 2013 225 233
65. P.M. Doraiswamy, and A.E. Finerock Metals in our minds: therapeutic implications for neurodegenerative disorders Lancet Neurol. 3 2004 431 434
66. Y. Ke, and Z.M. Qian Iron misregulation in the brain: a primary cause of neurodegenerative disorders Lancet Neurol. 2 2003 246 253
67. J. Chomoucka, and et al. Magnetic nanoparticles and targeted drug delivering Pharmacol. Res. 62 2010 144 149
68. Wahajuddin, and S. Arora Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers Int. J. Nanomed. 7 2012 3445 3471