The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas

Biomaterials

Volumn 32, Issue 2, 2011, Pages 516-527

  Hua, Mu Yi ^a   Liu, Hao Li ^a   Yang, Hung Wei ^a   Chen, Pin Yuan ^a,b   Tsai, Rung Ywan ^c   Huang, Chiung Yin ^b   Tseng, I Chou ^b   Lyu, Lee Ang ^a   Ma, Chih Chun ^a   Tang, Hsiang Jun ^a   Yen, Tzu Chen ^d   Wei, Kuo Chen ^b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

BCNU; Drug nanocarrier; Magnetic nanoparticle; Malignant glioma; Polyaniline derivative

Indexed keywords

BCNU; MAGNETIC NANOPARTICLES; MALIGNANT GLIOMA; NANOCARRIERS; POLYANILINE DERIVATIVE;

ACIDS; ANILINE; CHEMOTHERAPY; DRUG DELIVERY; DRUG DOSAGE; FATTY ACIDS; NANOPARTICLES; POLYANILINE; SUPERPARAMAGNETISM; THERMODYNAMIC STABILITY; TUMORS;

NANOMAGNETICS;

CARMUSTINE; MAGNETIC NANOPARTICLE; MAGNETITE; POLYANILINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG HALF LIFE; DRUG STABILITY; GLIOMA; IN VITRO STUDY; IN VIVO CULTURE; MAGNETIC FIELD; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; STRUCTURE ACTIVITY RELATION; THERAPY EFFECT; THERMOSTABILITY;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CARMUSTINE; CELL LINE; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; GLIOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 78449253583     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.09.065     Document Type: Article

References (50)

1. Kim G.Y., Tyler B.M., Tupper M.M., Karp J.M., Langer R.S., Brem H., et al. Resorbable polymer microchips releasing BCNU inhibit tumor growth in the rat 9L flank model. J Control Release 2007, 123:172-178.
2. Legler J.M., Ries L.A., Smith M.A., Warren J.L., Heineman E.F., Kaplan R.S., et al. Cancer surveillance series [corrected]: brain and other central nervous system cancers: recent trends in incidence and mortality. J Natl Cancer Inst 1999, 91:1382-1390.
3. Gloeckler Ries L.A., Reichman M.E., Lewis D.R., Hankey B.F., Edwards B.K. Cancer survival and incidence from the Surveillance, Epidemiology, and End Results (SEER) program. Oncologist 2003, 8:541-552.
4. Chae G.S., Lee J.S., Kim S.H., Seo K.S., Kim M.S., Lee H.B., et al. Enhancement of the stability of BCNU using self-emulsifying drug delivery systems (SEDDS) and in vitro antitumor activity of self-emulsified BCNU-loaded PLGA wafer. Int J Pharm 2005, 301:6-14.
5. Kornblith P.L., Walker M. Chemotherapy for malignant gliomas. J Neurosurg 1988, 68:1-17.
6. 6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma. Cancer Res 2000, 60:6307-6310.
7. Xu X., Chen X., Xu X., Lu T., Wang X., Yang L., et al. BCNU-loaded PEG-PLLA ultrafine fibers and their in vitro antitumor activity against glioma C6 cells. J Control Release 2006, 114:307-316.
8. Seong H., An T.K., Khang G., Choi S.-U., Lee C.O., Lee H.B. BCNU-loaded poly(d, l-lactide-co-glycolide) wafer and antitumor activity against XF-498 human CNS tumor cells in vitro. Int J Pharm 2003, 251:1-12.
9. Li Y., Shawgo R.S., Tyler B., Henderson P.T., Vogel J.S., Rosenberg A., et al. In vivo release from a drug delivery MEMS device. J Control Release 2004, 100:211-219.
10. Richards Grayson A.C., Choi I.S., Tyler B.M., Wang P.P., Brem H., Cima M.J., et al. Multi-pulse drug delivery from a resorbable polymeric microchip device. Nat Mater 2003, 2:767-772.
11. Hong J., Xu D., Gong P., Yu J., Ma H., Yao S. Covalent-bonded immobilization of enzyme on hydrophilic polymer covering magnetic nanogels. Microporous Mesoporous Mater 2008, 109:470-477.
12. Dobson J. Magnetic nanoparticles for drug delivery. Drug Dev Res 2006, 67:55-60.
13. Horák D., Babič M., Macková H., Beneš M.J. Preparation and properties of magnetic nano- and microsized particles for biological and environmental separations. J Sep Sci 2007, 30:1751-1772.
14. Gamarra L.F., Brito G.E.S., Pontuschka W.M., Amaro E., Parma A.H.C., Goya G.F. Biocompatible superparamagnetic iron oxide nanoparticles used for contrast agents: a structural and magnetic study. J Magn Magn Mater 2005, 289:439-441.
15. 4 nanoparticles and their biomedical applications. Biomaterials 2005, 26:729-738.
16. Asmatulu R., Zalich M.A., Claus R.O., Riffle J.S. Synthesis, characterization and targeting of biodegradable magnetic nanocomposite particles by external magnetic fields. J Magn Magn Mater 2005, 292:108-119.
17. Ma Y.-H., Hsu Y.-W., Chang Y.-J., Hua M.-Y., Chen J.-P., Wu T. Intra-arterial application of magnetic nanoparticles for targeted thrombolytic therapy: a rat embolic model. J Magn Magn Mater 2007, 311:34-36.
18. Ma Y.-H., Wu S.-Y., Wu T., Chang Y.-J., Hua M.-Y., Chen J.-P. Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles. Biomaterials 2009, 30:3343-3351.
19. Lee G., Kim J., Lee J.-h. Development of magnetically separable polyaniline nanofibers for enzyme immobilization and recovery. Enzym Microb Technol 2008, 42:466-472.
20. Lee D.-G., Ponvel K.M., Kim M., Hwang S., Ahn I.-S., Lee C.-H. Immobilization of lipase on hydrophobic nano-sized magnetite particles. J Mol Catal B Enzym 2009, 57:62-66.
21. Liberti P.A., Rao C.G., Terstappen L.W.M.M. Optimization of ferrofluids and protocols for the enrichment of breast tumor cells in blood. J Magn Magn Mater 2001, 225:301-307.
22. Sonvico F., Mornet S., Vasseur S., Dubernet C., Jaillard D., Degrouard J., et al. Folate-conjugated iron oxide nanoparticles for solid tumor targeting as potential specific magnetic hyperthermia mediators: synthesis, physicochemical characterization, and in vitro experiments. Bioconjug Chem 2005, 16:1181-1188.
23. Kohler N., Sun C., Wang J., Zhang M. Methotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cells. Langmuir 2005, 21:8858-8864.
24. Zhang J.L., Srivastava R.S., Misra R.D.K. Core-shell magnetite nanoparticles surface encapsulated with smart stimuli-responsive polymer: synthesis, characterization, and LCST of viable drug-targeting delivery system. Langmuir 2007, 23:6342-6351.
25. Zhang Y., Zhang J. Surface modification of monodisperse magnetite nanoparticles for improved intracellular uptake to breast cancer cells. J Colloid Interface Sci 2005, 283:352-357.
26. Hu F., Li Z., Tu C., Gao M. Preparation of magnetite nanocrystals with surface reactive moieties by one-pot reaction. J Colloid Interface Sci 2007, 311:469-474.
27. Guimard N.K., Gomez N., Schmidt C.E. Conducting polymers in biomedical engineering. Prog Polym Sci 2007, 32:876-921.
28. Wang C.H., Dong Y.Q., Sengothi K., Tan K.L., Kang E.T. In-vivo tissue response to polyaniline. Synth Met 1999, 102:1313-1314.
29. Li M., Guo Y., Wei Y., MacDiarmid A.G., Lelkes P.I. Electrospinning polyaniline-contained gelatin nanofibers for tissue engineering applications. Biomaterials 2006, 27:2705-2715.
30. Kim H.-S., Hobbs H.L., Wang L., Rutten M.J., Wamser C.C. Biocompatible composites of polyaniline nanofibers and collagen. Synth Met 2009, 159:1313-1318.
31. Dispenza C., Leone M., Lo Presti C., Librizzi F., Spadaro G., Vetri V. Optical properties of biocompatible polyaniline nano-composites. J Non-Cryst Solids 2006, 352:3835-3840.
32. Hua M.Y., Yang H.W., Chuang C.K., Tsai R.Y., Chen W.J., Chuang K.L., et al. Magnetic-nanoparticle-modified paclitaxel for targeted therapy for prostate cancer. Biomaterials 2010, 31:7355-7363.
33. Fang N., Tan W.J., Leong K.W., Mao H.-Q., Chan V. pH responsive adhesion of phospholipid vesicle on poly(acrylic acid) cushion grafted to poly(ethylene terephthalate) surface. Colloids Surf B Biointerfaces 2005, 42:245-252.
34. Whelpton R., Watkins G., Curry S.H. Bratton-Marshall and liquid-chromatographic methods compared for determination of sulfamethazine acetylator status. Clin Chem 1981, 27:1911-1914.
35. Ueda-Kawamitsu H., Lawson T.A., Gwilt P.R. In vitro pharmacokinetics and pharmacodynamics of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Biochem Pharmacol 2002, 63:1209-1218.
36. 2 detection of tumor invasion within segmented components of glioblastoma multiforme. J Magn Reson Imaging 2009, 29:251-257.
37. Liu H.L., Hua M.Y., Chen P.Y., Chu P.C., Pan C.H., Yang H.W., et al. Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment. Radiology 2010, 255:415-425.
38. Ma H.-l., Qi X.-r., Maitani Y., Nagai T. Preparation and characterization of superparamagnetic iron oxide nanoparticles stabilized by alginate. Int J Pharm 2007, 333:177-186.
39. 12 prepared by sol-gel method. Phys Rev B Condens Matter 2004, 354:104-107.
40. 2 nanoparticles with surfactants. Colloids Surf A Physicochem Eng Asp 2009, 348:270-275.
41. 2 agglomerates in electrostatically stabilized aqueous dispersions. Powder Technol 2005, 160:121-126.
42. Nam H.Y., Kwon S.M., Chung H., Lee S.-Y., Kwon S.-H., Jeon H., et al. Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J Control Release 2009, 135:259-267.
43. Murray R.K., Granner D.K. Membranes: structure, assembly, and function. Harper's biochemistry 2000, 505-532. McGraw-Hill, New York. 25th ed. R.K. Murray, D.K. Granner, P.A. Mayes, V.W. Rodwell (Eds.).
44. Rajski S.R., Williams R.M. DNA cross-linking agents as antitumor drugs. Chem Rev 1998, 98:2723-2795.
45. Chen F.-X., Bodell W.J., Liang G., Gold B. Reaction of N-(2-chloroethyl)-N-nitrosoureas with DNA: effect of buffers on DNA adduction, cross-linking, and cytotoxicity. Chem Res Toxicol 1996, 9:208-214.
46. 1-deoxyguanosinyl]-ethane in DNA treated with N,N′-bis(2-chloroethyl)-N-nitrosourea. Cancer Res 1982, 42:3102-3105.
47. 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc Natl Acad Sci U S A 1990, 87:5368-5372.
48. Chertok B., Moffat B.A., David A.E., Yu F., Bergemann C., Ross B.D., et al. Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors. Biomaterials 2008, 29:487-496.
49. Chen P.Y., Liu H.L., Hua M.Y., Yang H.W., Huang C.Y., Chu P.C., et al. Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment. Neuro-oncology 2010, 12:1050-1060.
50. Begley D.J. Delivery of therapeutic agents to the central nervous system: the problems and the possibilities. Pharmacol Ther 2004, 104:29-45.