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Volumn 16, Issue 1, 2014, Pages 38-49

Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma

Author keywords

glioma; Hsp70; magnetic nanoparticles; SPION; targeted delivery

Indexed keywords

ANTINEOPLASTIC AGENT; CONTRAST MEDIUM; GADOBUTROL; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 70 SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE CONJUGATE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; MAGNETITE NANOPARTICLE; RECOMBINANT PROTEIN;

EID: 84891525236     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/not141     Document Type: Article
Times cited : (55)

References (52)
  • 1
    • 46749132642 scopus 로고    scopus 로고
    • Multifunctional magnetic nanoparticles for targeted imaging and therapy
    • Mccarthy JR, Weissleder R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev. 2008;60: 1241-1251
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1241-1251
    • Mccarthy, J.R.1    Weissleder, R.2
  • 2
    • 84858407826 scopus 로고    scopus 로고
    • Magnetic nanoparticles: An emerging technology for malignant brain tumor imaging and therapy
    • Wankhede M, Bouras A, Kaluzova M, Hadjipanayis CG. Magnetic nanoparticles: An emerging technology for malignant brain tumor imaging and therapy. Expert Rev Clin Pharmacol. 2012;5:173-186
    • (2012) Expert Rev Clin Pharmacol , vol.5 , pp. 173-186
    • Wankhede, M.1    Bouras, A.2    Kaluzova, M.3    Hadjipanayis, C.G.4
  • 3
    • 70349908442 scopus 로고    scopus 로고
    • Enhancement in treatment planning for magnetic nanoparticle hyperthermia: Optimization of the heat absorption pattern
    • Salloum M, Ma R, Zhu L. Enhancement in treatment planning for magnetic nanoparticle hyperthermia: Optimization of the heat absorption pattern. Int J Hyperthermia. 2009;25:309-321
    • (2009) Int J Hyperthermia , vol.25 , pp. 309-321
    • Salloum, M.1    Ma, R.2    Zhu, L.3
  • 4
    • 80855147641 scopus 로고    scopus 로고
    • Cancer hyperthermia using magnetic nanoparticles
    • Kobayashi T. Cancer hyperthermia using magnetic nanoparticles. Biotechnol J. 2011;6:1342-1347
    • (2011) Biotechnol J. , vol.6 , pp. 1342-1347
    • Kobayashi, T.1
  • 5
    • 33646886334 scopus 로고    scopus 로고
    • The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma
    • Jordan A, Scholz R, Maier-Hauff K, et al. The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma. J Neurooncol. 2006;78:7-14
    • (2006) J Neurooncol , vol.78 , pp. 7-14
    • Jordan, A.1    Scholz, R.2    Maier-Hauff, K.3
  • 6
    • 84866757724 scopus 로고    scopus 로고
    • Multifunctional magnetic Fe3O4 nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
    • Ren Y, Zhang H, Chen B, et al. Multifunctional magnetic Fe3O4 nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance. Int J Nanomedicine. 2012;7: 2261-2269
    • (2012) Int J Nanomedicine , vol.7 , pp. 2261-2269
    • Ren, Y.1    Zhang, H.2    Chen, B.3
  • 7
    • 84863011505 scopus 로고    scopus 로고
    • Cell-delivered magnetic nanoparticles caused hyperthermia-mediated increased survival in a murine pancreatic cancer model
    • Basel M, Balivada S, Wang H, et al. Cell-delivered magnetic nanoparticles caused hyperthermia-mediated increased survival in a murine pancreatic cancer model. Int J Nanomedicine. 2012;7: 297-306
    • (2012) Int J Nanomedicine , vol.7 , pp. 297-306
    • Basel, M.1    Balivada, S.2    Wang, H.3
  • 8
    • 34249858538 scopus 로고    scopus 로고
    • Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: Results of a prospective phase I trial
    • Johannsen M, Gneveckow U, Taymoorian K, et al. Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: Results of a prospective phase I trial. Int J Hyperthermia. 2007;23:315-323
    • (2007) Int J Hyperthermia , vol.23 , pp. 315-323
    • Johannsen, M.1    Gneveckow, U.2    Taymoorian, K.3
  • 9
    • 33845698534 scopus 로고    scopus 로고
    • Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: Results of a feasibility study on patients with glioblastoma multiforme
    • Maier-Hauff K, Rothe R, Scholz R, et al. Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: Results of a feasibility study on patients with glioblastoma multiforme. J Neurooncol. 2007;81:53-60
    • (2007) J Neurooncol , vol.81 , pp. 53-60
    • Maier-Hauff, K.1    Rothe, R.2    Scholz, R.3
  • 10
    • 79959846524 scopus 로고    scopus 로고
    • Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastomamultiforme
    • Maier-Hauff K, Ulrich F, Nestler D, et al. Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastomamultiforme. J Neurooncol. 2011;103(2):317-324
    • (2011) J Neurooncol , vol.103 , Issue.2 , pp. 317-324
    • Maier-Hauff, K.1    Ulrich, F.2    Nestler, D.3
  • 11
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomized phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomized phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10:459-466
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 12
    • 11044222650 scopus 로고    scopus 로고
    • Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    • Gupta AK, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials. 2005; 26:3995-4021
    • (2005) Biomaterials , vol.26 , pp. 3995-4021
    • Gupta, A.K.1    Gupta, M.2
  • 13
    • 77955388676 scopus 로고    scopus 로고
    • EGFRvIII antibody conjugated iron oxide nanoparticles for MRI guided convectionenhanced delivery and targeted therapy of glioblastoma
    • Hadjipanayis CG, Machaidze R, Kaluzova M, et al. EGFRvIII antibody conjugated iron oxide nanoparticles for MRI guided convectionenhanced delivery and targeted therapy of glioblastoma. Cancer Res. 2010;70:6303-6312
    • (2010) Cancer Res , vol.70 , pp. 6303-6312
    • Hadjipanayis, C.G.1    Machaidze, R.2    Kaluzova, M.3
  • 14
    • 66149118650 scopus 로고    scopus 로고
    • Magnetic nanoparticle of Fe3O4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells
    • Chen BA, Cheng J, Shen MF, et al. Magnetic nanoparticle of Fe3O4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells. Int J Nanomedicine. 2009;4:65-71
    • (2009) Int J Nanomedicine , vol.4 , pp. 65-71
    • Chen, B.A.1    Cheng, J.2    Shen, M.F.3
  • 15
    • 84871847830 scopus 로고    scopus 로고
    • Magnetic epidermal growth factor for targeted delivery to grafted tumor in mouse model
    • Nikolaev BP, Marchenko YY, Yakovleva LY, et al. Magnetic epidermal growth factor for targeted delivery to grafted tumor in mouse model. IEEE Trans Magn. 2013;49:1-7
    • (2013) IEEE Trans Magn , vol.49 , pp. 1-7
    • Nikolaev, B.P.1    Marchenko, Y.Y.2    Yakovleva, L.Y.3
  • 16
    • 26044433779 scopus 로고    scopus 로고
    • Message in a bottle: Role of the 70 kDa HSP in anti-Tumor immunity
    • Calderwood SK, Theriault JR, Gong J. Message in a bottle: Role of the 70 kDa HSP in anti-Tumor immunity. Eur J Cancer. 2005;35:2518-2527
    • (2005) Eur J Cancer , vol.35 , pp. 2518-2527
    • Calderwood, S.K.1    Theriault, J.R.2    Gong, J.3
  • 17
    • 84874921468 scopus 로고    scopus 로고
    • Heat shock proteins, autoimmunity, and cancer treatment
    • Calderwood SK, Stevenson MA, Murshid A. Heat shock proteins, autoimmunity, and cancer treatment. Autoimmune Dis. 2012;2012: 486069
    • (2012) Autoimmune Dis , vol.2012 , pp. 486069
    • Calderwood, S.K.1    Stevenson, M.A.2    Murshid, A.3
  • 18
    • 84865175386 scopus 로고    scopus 로고
    • The role of heat shock proteins in antigen cross presentation
    • Murshid A, Gong J, Calderwood SK. The role of heat shock proteins in antigen cross presentation. Front Immunol. 2012;3:63
    • (2012) Front Immunol , vol.3 , pp. 63
    • Murshid, A.1    Gong, J.2    Calderwood, S.K.3
  • 19
    • 17044421317 scopus 로고    scopus 로고
    • Death receptor-mediated apoptosis in human malignant glioma cells: Modulation by the CD40/CD40L system
    • Wischhusen J, Schneider D, Mittelbronn M, et al. Death receptor-mediated apoptosis in human malignant glioma cells: Modulation by the CD40/CD40L system. J Neuroimmunol. 2005;162: 28-42
    • (2005) J Neuroimmunol , vol.162 , pp. 28-42
    • Wischhusen, J.1    Schneider, D.2    Mittelbronn, M.3
  • 20
    • 84870539609 scopus 로고    scopus 로고
    • Activation of CD40 by soluble recombinant human CD40 ligand inhibits human glioma cells proliferation via nuclear factor-kB signaling pathway
    • Zhang Y, Huang T, Hu Y, Wang Y. Activation of CD40 by soluble recombinant human CD40 ligand inhibits human glioma cells proliferation via nuclear factor-kB signaling pathway. J Huazhong Univ Sci Technolog Med Sci. 2012;32:691-696
    • (2012) J Huazhong Univ Sci Technolog Med Sci , vol.32 , pp. 691-696
    • Zhang, Y.1    Huang, T.2    Hu, Y.3    Wang, Y.4
  • 21
    • 84865131007 scopus 로고    scopus 로고
    • TNFa regulates the localization of CD40 in lipid rafts of glioma cells
    • Tewari R, Choudhury SR, Mehta VS, Sen E. TNFa regulates the localization of CD40 in lipid rafts of glioma cells. Mol Biol Rep. 2012; 39:8695-8699
    • (2012) Mol Biol Rep , vol.39 , pp. 8695-8699
    • Tewari, R.1    Choudhury, S.R.2    Mehta, V.S.3    Sen, E.4
  • 22
    • 66149117488 scopus 로고    scopus 로고
    • Treating human cancers with heat shock protein-peptide complexes: The road ahead
    • Srivastava PK, Callahan MK, Mauri MM. Treating human cancers with heat shock protein-peptide complexes: The road ahead. Expert Opin Biol Ther. 2009;9:179-186
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 179-186
    • Srivastava, P.K.1    Callahan, M.K.2    Mauri, M.M.3
  • 23
    • 0742269451 scopus 로고    scopus 로고
    • Antitumor effects of combined therapy of recombinant heat shock protein 70 and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanoma
    • Ito A, Matsuoka F, Honda H, Kobayashi T. Antitumor effects of combined therapy of recombinant heat shock protein 70 and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanoma. Cancer Immunol Immunother. 2004;53:26-32
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 26-32
    • Ito, A.1    Matsuoka, F.2    Honda, H.3    Kobayashi, T.4
  • 24
    • 0019541337 scopus 로고
    • Preparation of aqueous magnetic liquids in alkaline and acidic media
    • Massart R. Preparation of aqueous magnetic liquids in alkaline and acidic media. IEEE Trans Magn. 1981;17:1247-1248
    • (1981) IEEE Trans Magn , vol.17 , pp. 1247-1248
    • Massart, R.1
  • 25
    • 79958262555 scopus 로고    scopus 로고
    • Kinetics of chaperone activity of proteins Hsp70 and Hdj1 in human leukemia U937 cells after preconditioning with thermal shock or compound U133
    • Lazarev VF, Onokhin KV, Antimonova OI, et al. Kinetics of chaperone activity of proteins Hsp70 and Hdj1 in human leukemia U937 cells after preconditioning with thermal shock or compound U133. Biochemistry (Moscow). 2011;76:590-595
    • (2011) Biochemistry (Moscow , vol.76 , pp. 590-595
    • Lazarev, V.F.1    Onokhin, K.V.2    Antimonova, O.I.3
  • 26
    • 0034284227 scopus 로고    scopus 로고
    • Saturation, competition, and specificity in interaction of heat shock proteins (hsp) gp96, hsp90, and hsp70 with CD11b+ Cells
    • Binder RJ, Harris ML, Menoret A, Srivastava PK. Saturation, competition, and specificity in interaction of heat shock proteins (hsp) gp96, hsp90, and hsp70 with CD11b+ Cells. J Immunol. 2000;165:2582-2587
    • (2000) J Immunol , vol.165 , pp. 2582-2587
    • Binder, R.J.1    Harris, M.L.2    Menoret, A.3    Srivastava, P.K.4
  • 27
    • 78651236770 scopus 로고    scopus 로고
    • Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides
    • Zhou J, Tryggestad E, Wen Z, et al. Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides. Nat Med. 2011;17:130-134
    • (2011) Nat Med , vol.17 , pp. 130-134
    • Zhou, J.1    Tryggestad, E.2    Wen, Z.3
  • 28
    • 84858615014 scopus 로고    scopus 로고
    • Iron oxide nanoparticles for targeted cancer imaging and diagnostics
    • Rosen JE, Chan L, Shieh DB, Gu FX. Iron oxide nanoparticles for targeted cancer imaging and diagnostics. Nanomedicine. 2012;8:275-290
    • (2012) Nanomedicine , vol.8 , pp. 275-290
    • Rosen, J.E.1    Chan, L.2    Shieh, D.B.3    Gu, F.X.4
  • 29
    • 78049397567 scopus 로고    scopus 로고
    • Heat shock protein 90 mediates efficient antigen cross-presentation through the scavenger receptor expressed by endothelial cells-I
    • Murshid A, Gong J, Calderwood SK. Heat shock protein 90 mediates efficient antigen cross-presentation through the scavenger receptor expressed by endothelial cells-I. J Immunol. 2010;185:2903-2917
    • (2010) J Immunol , vol.185 , pp. 2903-2917
    • Murshid, A.1    Gong, J.2    Calderwood, S.K.3
  • 31
    • 18644364531 scopus 로고    scopus 로고
    • Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation
    • Delneste Y, Magistrelli G, Gauchat J, et al. Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity. 2002;17:353-362
    • (2002) Immunity , vol.17 , pp. 353-362
    • Delneste, Y.1    Magistrelli, G.2    Gauchat, J.3
  • 32
    • 33845446813 scopus 로고    scopus 로고
    • Role of scavenger receptors in the binding and internalization of heat shock protein 70
    • Theriault JR, Adachi H, Calderwood SK. Role of scavenger receptors in the binding and internalization of heat shock protein 70. J Immunol. 2006;177:8604-8611
    • (2006) J Immunol , vol.177 , pp. 8604-8611
    • Theriault, J.R.1    Adachi, H.2    Calderwood, S.K.3
  • 34
    • 70349213245 scopus 로고    scopus 로고
    • The Dectin-2 family of C-Type lectins in immunity and homeostasis
    • Graham LM, Brown GD. The Dectin-2 family of C-Type lectins in immunity and homeostasis. Cytokine. 2009;48:148-155
    • (2009) Cytokine , vol.48 , pp. 148-155
    • Graham, L.M.1    Brown, G.D.2
  • 36
    • 0035070198 scopus 로고    scopus 로고
    • CD91 is a common receptor for heat shock proteins Gp96, Hsp90, Hsp70, and calreticulin
    • Basu S, Binder RJ, Ramalingam T, Srivastava PK. CD91 is a common receptor for heat shock proteins Gp96, Hsp90, Hsp70, and calreticulin. Immunity. 2001;14:303-313
    • (2001) Immunity , vol.14 , pp. 303-313
    • Basu, S.1    Binder, R.J.2    Ramalingam, T.3    Srivastava, P.K.4
  • 37
    • 0034113617 scopus 로고    scopus 로고
    • HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
    • Asea A, Kraeft SK, Kurt-Jones EA, et al. HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med. 2000;6:435-442
    • (2000) Nat Med , vol.6 , pp. 435-442
    • Asea, A.1    Kraeft, S.K.2    Kurt-Jones, E.A.3
  • 38
    • 0037177833 scopus 로고    scopus 로고
    • HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway
    • Vabulas RM, Ahmad-Nejad P, Ghose S, et al. HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J Biol Chem. 2002;277:15107-15112
    • (2002) J Biol Chem , vol.277 , pp. 15107-15112
    • Vabulas, R.M.1    Ahmad-Nejad, P.2    Ghose, S.3
  • 39
    • 0037144808 scopus 로고    scopus 로고
    • CD40,anextracellular receptor for binding and uptake of Hsp70-peptide complexes
    • Becker T, Hartl FU, Wieland F. CD40,anextracellular receptor for binding and uptake of Hsp70-peptide complexes. J Cell Biol. 2002;158: 1277-1285
    • (2002) J Cell Biol , vol.158 , pp. 1277-1285
    • Becker, T.1    Hartl, F.U.2    Wieland, F.3
  • 40
    • 14844327760 scopus 로고    scopus 로고
    • Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
    • Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M. Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell. 2005;120(5): 649-661
    • (2005) Cell , vol.120 , Issue.5 , pp. 649-661
    • Kamata, H.1    Honda, S.2    Maeda, S.3    Chang, L.4    Hirata, H.5    Karin, M.6
  • 41
    • 22344447847 scopus 로고    scopus 로고
    • Oxidative stress activates transcription factor NF-kB-mediated protective signaling in primary rat neuronal cultures
    • Kratsovnik E, Bromberg Y, Sperling O, Zoref-Shani E. Oxidative stress activates transcription factor NF-kB-mediated protective signaling in primary rat neuronal cultures. J Mol Neurosci. 2005;26(1):27-32
    • (2005) J Mol Neurosci , vol.26 , Issue.1 , pp. 27-32
    • Kratsovnik, E.1    Bromberg, Y.2    Sperling, O.3    Zoref-Shani, E.4
  • 43
    • 35748944844 scopus 로고    scopus 로고
    • From death receptor to reactive oxygen species and cJun N-Terminal protein kinase: The receptor-interacting protein 1 odyssey
    • Temkin V, Karin M. From death receptor to reactive oxygen species and cJun N-Terminal protein kinase: The receptor-interacting protein 1 odyssey. Immunol Rev. 2007;220(1):8-21
    • (2007) Immunol Rev , vol.220 , Issue.1 , pp. 8-21
    • Temkin, V.1    Karin, M.2
  • 44
    • 27644530602 scopus 로고    scopus 로고
    • LPS induces CD40 gene expression through the activation of NF-kB and STAT-1a in macrophages and microglia
    • Qin H, Wilson CA, Lee SJ, Zhao X, Benveniste EN. LPS induces CD40 gene expression through the activation of NF-kB and STAT-1a in macrophages and microglia. Blood. 2005;106:3114-3122
    • (2005) Blood , vol.106 , pp. 3114-3122
    • Qin, H.1    Wilson, C.A.2    Lee, S.J.3    Zhao, X.4    Benveniste, E.N.5
  • 46
    • 0037096172 scopus 로고    scopus 로고
    • Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
    • Triantafilou M, Miyake K, Golenbock DT, Triantafilou K. Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation. J Cell Sci. 2002; 115:2603-2611
    • (2002) J Cell Sci , vol.115 , pp. 2603-2611
    • Triantafilou, M.1    Miyake, K.2    Golenbock, D.T.3    Triantafilou, K.4
  • 47
    • 0037484291 scopus 로고    scopus 로고
    • Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release
    • Broquet AH, Thomas G, Masliah J, Trugnan G, Bachelet M. Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release. J Biol Chem. 2003; 278:21601-21606
    • (2003) J Biol Chem , vol.278 , pp. 21601-21606
    • Broquet, A.H.1    Thomas, G.2    Masliah, J.3    Trugnan, G.4    Bachelet, M.5
  • 48
    • 44849133308 scopus 로고    scopus 로고
    • Tumor-specific hsp70plasma membrane localization is enabled by the glycosphingolipid Gb3
    • Gehrmann M, Liebisch G, Schmitz G, et al. Tumor-specific hsp70plasma membrane localization is enabled by the glycosphingolipid Gb3. PLoS One. 2008;3(4):e1925
    • (2008) PLoS One , vol.3 , Issue.4
    • Gehrmann, M.1    Liebisch, G.2    Schmitz, G.3
  • 49
    • 0034470379 scopus 로고    scopus 로고
    • Vascular microenvironment in gliomas
    • Vajkoczy P, Menger MD. Vascular microenvironment in gliomas. J Neurooncol. 2000;50:99-108
    • (2000) J Neurooncol , vol.50 , pp. 99-108
    • Vajkoczy, P.1    Menger, M.D.2
  • 50
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor TT, Sorensen AG, di Tomaso E, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell. 2007;11:83-95
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    Di Tomaso, E.3
  • 51
    • 36048943923 scopus 로고    scopus 로고
    • Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors
    • Chertok B, Moffat BA, David AE, et al. Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors. Biomaterials. 2008;29:487-496
    • (2008) Biomaterials , vol.29 , pp. 487-496
    • Chertok, B.1    Moffat, B.A.2    David, A.E.3
  • 52
    • 80054795004 scopus 로고    scopus 로고
    • Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma
    • Agemy L, Friedmann-Morvinski D, Kotamraju VR, et al. Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. Proc Natl Acad Sci U S A. 2011;108:17450-17455
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , pp. 17450-17455
    • Agemy, L.1    Friedmann-Morvinski, D.2    Kotamraju, V.R.3


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