Long term biotransformation and toxicity of dimercaptosuccinic acid-coated magnetic nanoparticles support their use in biomedical applications

Journal of Controlled Release

Volumn 171, Issue 2, 2013, Pages 225-233

  Mejías, Raquel ^a   Gutiérrez, Lucía ^b   Salas, Gorka ^b,c   Pérez Yagüe, Sonia ^a   Zotes, Teresa M ^a   Lázaro, Francisco J ^d   Morales, María P ^b   Barber, Domingo F ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b INSTITUTO DE CIENCIA DE MATERIALES DE MADRID   (Spain)

^c INSTITUTO MADRILEÑO DE ESTUDIOS AVANZADOS EN NANOCIENCIA IMDEA NANOCIENCIA   (Spain)

^d Instituto de Ciencia de Materiales de Aragón   (Spain)

Author keywords

Biocompatibility; Biodistribution; Biotransformation; Cytotoxicity; Iron oxide; Nanoparticle

Indexed keywords

BIOCOMPATIBILITY; BIOCONVERSION; CELL DEATH; CYTOTOXICITY; IRON; IRON OXIDES; MAGNETIC SUSCEPTIBILITY; MAGNETISM; MAGNETITE NANOPARTICLES; MEDICAL APPLICATIONS; NANOPARTICLES; SUPERPARAMAGNETISM; TOXICITY;

BIODISTRIBUTIONS; BIOMEDICAL APPLICATIONS; BIOTRANSFORMATION; DIMERCAPTOSUCCINIC ACIDS; DMSA-COATED MAGNETITE NANOPARTICLES; MAGNETIC NANO-PARTICLES; MAGNETIC SUSCEPTIBILITY MEASUREMENTS; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES;

NANOMAGNETICS;

IRON; MAGNETIC NANOPARTICLE; NANOCOATING; SUCCIMER; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

ALTERNATING CURRENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOMEDICAL ENGINEERING; BIOTRANSFORMATION; CELL CYCLE; CELL VIABILITY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LIVER; LIVER CELL; LUNG PARENCHYMA; MAGNETISM; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SPLEEN;

BIOCOMPATIBILITY; BIODISTRIBUTION; BIOTRANSFORMATION; CYTOTOXICITY; IRON OXIDE; NANOPARTICLE;

ANIMALS; BIOTRANSFORMATION; CASPASE 3; CELL LINE; CELL SURVIVAL; FECES; FEMALE; GLUTATHIONE; IRON; KIDNEY; LIVER; LUNG; MAGNETITE NANOPARTICLES; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; OXIDATIVE STRESS; SPLEEN; SUCCIMER;

EID: 84881492415     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.07.019     Document Type: Article

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