Homodimerization Protects the Amyloid Precursor Protein C99 Fragment from Cleavage by Secretase

Biochemistry

Volumn 54, Issue 40, 2015, Pages 6149-6152

  Winkler, Edith ^a   Julius, Ayse ^b,c   Steiner, Harald ^a,d   Langosch, Dieter ^b,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c Munich Center for Integrated Protein Science   (Germany)

^d GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; DIMERIZATION; GLYCOPROTEINS; NEURODEGENERATIVE DISEASES;

ALZHEIMER'S DISEASE; AMYLOID PRECURSOR PROTEINS; C-TERMINAL FRAGMENTS; CYSTEINE RESIDUES; HOMODIMERIZATION; INTEGRAL MEMBRANE PROTEINS; SEQUENCE-SPECIFIC MANNER; TRANSMEMBRANE HELICES;

PROTEINS;

AMYLOID PRECURSOR PROTEIN; CYSTEINE; GAMMA SECRETASE; HOMODIMER; MEMBRANE PROTEIN; AMYLOID BETA PROTEIN; SECRETASE;

ALPHA HELIX; ALZHEIMER DISEASE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COVALENT BOND; CROSS LINKING; DIMERIZATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; CHEMISTRY; HUMAN; METABOLISM; PROTEIN MULTIMERIZATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; CYSTEINE; HUMANS; PROTEIN MULTIMERIZATION;

EID: 84944096738     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00986     Document Type: Article

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