Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair

DNA Repair

Volumn 35, Issue , 2015, Pages 85-89

  Çağlayan, Melike ^a   Wilson, Samuel H ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

8 oxo 7,8 dihydro 2' deoxyguanosine (8 oxoG); Abortive ligation products; Base excision repair (BER); DNA ligase; DNA polymerase (pol ); Ligation failure

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENOSINE PHOSPHATE; DNA DIRECTED DNA POLYMERASE BETA; OXIDIZING AGENT; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; XRCC1 PROTEIN; 8-OXO-7-HYDRODEOXYGUANOSINE; DANGEROUS GOODS; DEOXYGUANOSINE; DNA LIGASE;

DNA DAMAGE; DNA END JOINING REPAIR; DNA SYNTHESIS; ENVIRONMENTAL STRESS; ENZYME CONFORMATION; EXCISION REPAIR; GENE INSERTION; HUMAN; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SINGLE STRANDED DNA BREAK; ANALOGS AND DERIVATIVES; DANGEROUS GOODS; DNA REPAIR; DRUG EFFECTS; GENETICS; GENOMIC INSTABILITY; METABOLISM; TOXICITY;

DEOXYGUANOSINE; DNA DAMAGE; DNA LIGASES; DNA POLYMERASE BETA; DNA REPAIR; GENOMIC INSTABILITY; HAZARDOUS SUBSTANCES; HUMANS; OXIDANTS;

EID: 84944068163     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2015.09.010     Document Type: Review

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