Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 1, 2012, Pages 113-118

  Batra, Vinod K ^a   Shock, David D ^a   Beard, William A ^a   McKenna, Charles E ^b   Wilson, Samuel H ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Oxidative DNA lesion; X ray crystallography

Indexed keywords

8 HYDROXYGUANINE; ARGININE; DNA DIRECTED DNA POLYMERASE BETA; PHOSPHODIESTERASE;

ARTICLE; BASE PAIRING; CRYSTAL STRUCTURE; DNA CONFORMATION; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SUBSTRATE; EXCISION REPAIR; HYDROGEN BOND; MUTAGENESIS; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

BASE PAIRING; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA DAMAGE; DNA POLYMERASE BETA; GUANINE; HUMANS; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN CONFORMATION; TEMPLATES, GENETIC;

EID: 84856001654     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1112235108     Document Type: Article

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