-
1
-
-
33847051539
-
RIP1, a kinase on the crossroads of a cell's decision to live or die
-
PMID: 17301840
-
Festjens N, Vanden Berghe T, Cornelis S, Vandenabeele P. RIP1, a kinase on the crossroads of a cell's decision to live or die. Cell Death Differ 2007; 14: 400-10; PMID: 17301840; http://dx. doi. org/10. 1038/sj. cdd. 4402085.
-
(2007)
Cell Death Differ
, vol.14
, pp. 400-410
-
-
Festjens, N.1
Vanden Berghe, T.2
Cornelis, S.3
Vandenabeele, P.4
-
2
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
PMID: 18485876
-
Wang L, Du F, Wang X. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 2008; 133: 693-703; PMID: 18485876; http://dx. doi. org/10. 1016/j. cell. 2008. 03. 036.
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
3
-
-
84863486901
-
A novel role for RIP1 kinase in mediating TNFalpha production
-
PMID: 22695613
-
Christofferson DE, Li Y, Hitomi J, Zhou W, Upperman C, Zhu H, Gerber SA, Gygi S, Yuan J. A novel role for RIP1 kinase in mediating TNFalpha production. Cell Death Dis 2012; 3: e320; PMID: 22695613; http://dx. doi. org/10. 1038/cddis. 2012. 64.
-
(2012)
Cell Death Dis
, vol.3
-
-
Christofferson, D.E.1
Li, Y.2
Hitomi, J.3
Zhou, W.4
Upperman, C.5
Zhu, H.6
Gerber, S.A.7
Gygi, S.8
Yuan, J.9
-
4
-
-
77951251430
-
Necroptosis as an alternative form of programmed cell death
-
PMID: 20045303
-
Christofferson DE, Yuan J. Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol 2010; 22: 263-8; PMID: 20045303; http://dx. doi. org/10. 1016/j. ceb. 2009. 12. 003.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 263-268
-
-
Christofferson, D.E.1
Yuan, J.2
-
5
-
-
79960352030
-
A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage
-
PMID: 21606198
-
Yang Y, Xia F, Hermance N, Mabb A, Simonson S, Morrissey S, Gandhi P, Munson M, Miyamoto S, Kelliher MA. A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage. Mol Cell Biol 2011; 31: 2774-86; PMID: 21606198; http://dx. doi. org/10. 1128/MCB. 01139-10.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2774-2786
-
-
Yang, Y.1
Xia, F.2
Hermance, N.3
Mabb, A.4
Simonson, S.5
Morrissey, S.6
Gandhi, P.7
Munson, M.8
Miyamoto, S.9
Kelliher, M.A.10
-
6
-
-
80052692078
-
LUBAC regulates NFkappaB activation upon genotoxic stress by promoting linear ubiquitination of NEMO
-
PMID: 21811235
-
Niu J, Shi Y, Iwai K, Wu ZH. LUBAC regulates NFkappaB activation upon genotoxic stress by promoting linear ubiquitination of NEMO. EMBO J 2011; 30: 3741-53; PMID: 21811235; http://dx. doi. org/10. 1038/emboj. 2011. 264.
-
(2011)
EMBO J
, vol.30
, pp. 3741-3753
-
-
Niu, J.1
Shi, Y.2
Iwai, K.3
Wu, Z.H.4
-
7
-
-
44949240664
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
PMID: 18570872
-
Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Barker PA. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 2008; 30: 689-700; PMID: 18570872; http://dx. doi. org/10. 1016/j. molcel. 2008. 05. 014.
-
(2008)
Mol Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
Gillard, J.W.7
Jaquith, J.B.8
Morris, S.J.9
Barker, P.A.10
-
8
-
-
0036437307
-
Transcriptional and translational control in the Mammalian unfolded protein response
-
PMID: 12142265
-
Harding HP, Calfon M, Urano F, Novoa I, Ron D. Transcriptional and translational control in the Mammalian unfolded protein response. Annu Rev Cell Dev Biol 2002; 18: 575-99; PMID: 12142265; http://dx. doi. org/10. 1146/annurev. cellbio. 18. 011402. 160624.
-
(2002)
Annu Rev Cell Dev Biol
, vol.18
, pp. 575-599
-
-
Harding, H.P.1
Calfon, M.2
Urano, F.3
Novoa, I.4
Ron, D.5
-
9
-
-
84892832968
-
Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress
-
PMID: 23921951
-
Croft A, Tay KH, Boyd SC, Guo ST, Jiang CC, Lai F, Tseng HY, Jin L, Rizos H, Hersey P, et al. Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress. J Invest Dermatol 2014; 134: 488-97; PMID: 23921951; http://dx. doi. org/10. 1038/jid. 2013. 325.
-
(2014)
J Invest Dermatol
, vol.134
, pp. 488-497
-
-
Croft, A.1
Tay, K.H.2
Boyd, S.C.3
Guo, S.T.4
Jiang, C.C.5
Lai, F.6
Tseng, H.Y.7
Jin, L.8
Rizos, H.9
Hersey, P.10
-
10
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
PMID: 22116877
-
Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011; 334: 1081-6; PMID: 22116877; http://dx. doi. org/10. 1126/science. 1209038.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
11
-
-
84863740827
-
The impact of the unfolded protein response on human disease
-
PMID: 22733998
-
Wang S, Kaufman RJ. The impact of the unfolded protein response on human disease. J Cell Biol 2012; 197: 857-67; PMID: 22733998; http://dx. doi. org/10. 1083/jcb. 201110131.
-
(2012)
J Cell Biol
, vol.197
, pp. 857-867
-
-
Wang, S.1
Kaufman, R.J.2
-
12
-
-
33645154135
-
Cellular response to endoplasmic reticulum stress: A matter of life or death
-
PMID: 16397583
-
Boyce M, Yuan J. Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 2006; 13: 363-73; PMID: 16397583; http://dx. doi. org/10. 1038/sj. cdd. 4401817.
-
(2006)
Cell Death Differ
, vol.13
, pp. 363-373
-
-
Boyce, M.1
Yuan, J.2
-
13
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abetainduced cell death
-
PMID: 15123740
-
Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y, Manabe T, Yamagishi S, Bando Y, Imaizumi K, et al. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abetainduced cell death. J Cell Biol 2004; 165: 347-56; PMID: 15123740; http://dx. doi. org/10. 1083/jcb. 200310015.
-
(2004)
J Cell Biol
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
-
14
-
-
84889602190
-
Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress
-
PMID: 24240056
-
Tay KH, Luan Q, Croft A, Jiang CC, Jin L, Zhang XD, Tseng HY. Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress. Cell Signal 2014; 26: 287-94; PMID: 24240056; http://dx. doi. org/10. 1016/j. cellsig. 2013. 11. 008.
-
(2014)
Cell Signal
, vol.26
, pp. 287-294
-
-
Tay, K.H.1
Luan, Q.2
Croft, A.3
Jiang, C.C.4
Jin, L.5
Zhang, X.D.6
Tseng, H.Y.7
-
15
-
-
84876932914
-
FGF-2 prevents cancer cells from ER stressmediated apoptosis via enhancing proteasome-mediated Nck degradation
-
PMID: 23448571
-
Li B, Pi Z, Liu L, Zhang B, Huang X, Hu P, Chevet E, Yi P, Liu J. FGF-2 prevents cancer cells from ER stressmediated apoptosis via enhancing proteasome-mediated Nck degradation. Biochem J 2013; 452: 139-45; PMID: 23448571; http://dx. doi. org/10. 1042/BJ20120680.
-
(2013)
Biochem J
, vol.452
, pp. 139-145
-
-
Li, B.1
Pi, Z.2
Liu, L.3
Zhang, B.4
Huang, X.5
Hu, P.6
Chevet, E.7
Yi, P.8
Liu, J.9
-
16
-
-
35448958407
-
Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis
-
PMID: 17942905
-
Jiang CC, Chen LH, Gillespie S, Wang YF, Kiejda KA, Zhang XD, Hersey P. Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis. Cancer Res 2007; 67: 9750-61; PMID: 17942905; http://dx. doi. org/10. 1158/0008-5472. CAN-07-2047.
-
(2007)
Cancer Res
, vol.67
, pp. 9750-9761
-
-
Jiang, C.C.1
Chen, L.H.2
Gillespie, S.3
Wang, Y.F.4
Kiejda, K.A.5
Zhang, X.D.6
Hersey, P.7
-
17
-
-
53049105459
-
Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress
-
PMID: 18701495
-
Jiang CC, Lucas K, Avery-Kiejda KA, Wade M, deBock CE, Thorne RF, Allen J, Hersey P, Zhang XD. Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. Cancer Res 2008; 68: 6708-17; PMID: 18701495; http://dx. doi. org/10. 1158/0008-5472. CAN-08-0349.
-
(2008)
Cancer Res
, vol.68
, pp. 6708-6717
-
-
Jiang, C.C.1
Lucas, K.2
Avery-Kiejda, K.A.3
Wade, M.4
deBock, C.E.5
Thorne, R.F.6
Allen, J.7
Hersey, P.8
Zhang, X.D.9
-
18
-
-
65949106608
-
Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt
-
PMID: 19412428
-
Jiang CC, Yang F, Thorne RF, Zhu BK, Hersey P, Zhang XD. Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt. Neoplasia 2009; 11: 436-47; PMID: 19412428; http://dx. doi. org/10. 1593/neo. 09208.
-
(2009)
Neoplasia
, vol.11
, pp. 436-447
-
-
Jiang, C.C.1
Yang, F.2
Thorne, R.F.3
Zhu, B.K.4
Hersey, P.5
Zhang, X.D.6
-
19
-
-
80052074729
-
Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress
-
PMID: 21423203
-
Dong L, Jiang CC, Thorne RF, Croft A, Yang F, Liu H, de Bock CE, Hersey P, Zhang XD. Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress. Oncogene 2011; 30: 3716-26; PMID: 21423203; http://dx. doi. org/10. 1038/onc. 2011. 87.
-
(2011)
Oncogene
, vol.30
, pp. 3716-3726
-
-
Dong, L.1
Jiang, C.C.2
Thorne, R.F.3
Croft, A.4
Yang, F.5
Liu, H.6
de Bock, C.E.7
Hersey, P.8
Zhang, X.D.9
-
20
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
PMID: 17030611
-
Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S, Murakami T, Taniguchi M, Tanii I, Yoshinaga K, et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 2006; 26: 9220-31; PMID: 17030611; http://dx. doi. org/10. 1128/MCB. 01453-06.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
Morikawa, K.4
Kondo, S.5
Kanemoto, S.6
Murakami, T.7
Taniguchi, M.8
Tanii, I.9
Yoshinaga, K.10
-
21
-
-
33846211417
-
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
-
PMID: 16794605
-
Kouroku Y, Fujita E, Tanida I, Ueno T, Isoai A, Kumagai H, Ogawa S, Kaufman RJ, Kominami E, Momoi T. ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Cell Death Differ 2007; 14: 230-9; PMID: 16794605; http://dx. doi. org/10. 1038/sj. cdd. 4401984.
-
(2007)
Cell Death Differ
, vol.14
, pp. 230-239
-
-
Kouroku, Y.1
Fujita, E.2
Tanida, I.3
Ueno, T.4
Isoai, A.5
Kumagai, H.6
Ogawa, S.7
Kaufman, R.J.8
Kominami, E.9
Momoi, T.10
-
22
-
-
78649704325
-
Autophagy and metabolism
-
PMID: 21127245
-
Rabinowitz JD, White E. Autophagy and metabolism. Science 2010; 330: 1344-8; PMID: 21127245; http://dx. doi. org/10. 1126/science. 1193497.
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
23
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
PMID: 22966490
-
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012; 8: 445-544; PMID: 22966490; http://dx. doi. org/10. 4161/auto. 19496.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
Agholme, L.7
Agnello, M.8
Agostinis, P.9
Aguirre-Ghiso, J.A.10
-
24
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
PMID: 16239905
-
Kroemer G, Jaattela M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005; 5: 886-97; PMID: 16239905; http://dx. doi. org/10. 1038/nrc1738.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 886-897
-
-
Kroemer, G.1
Jaattela, M.2
-
25
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
PMID: 18191218
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132: 27-42; PMID: 18191218; http://dx. doi. org/10. 1016/j. cell. 2007. 12. 018.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
26
-
-
84859766593
-
Novel Insights into the Interplay between Apoptosis and Autophagy
-
PMID: 22496691
-
Rikiishi H. Novel Insights into the Interplay between Apoptosis and Autophagy. Int J Cell Biol 2012; 2012: 317645; PMID: 22496691; http://dx. doi. org/10. 1155/2012/317645.
-
(2012)
Int J Cell Biol
, vol.2012
-
-
Rikiishi, H.1
-
27
-
-
48249108314
-
Tumor suppression by autophagy through the management of metabolic stress
-
PMID: 18326941
-
Jin S, White E. Tumor suppression by autophagy through the management of metabolic stress. Autophagy 2008; 4: 563-6; PMID: 18326941; http://dx. doi. org/10. 4161/auto. 5830.
-
(2008)
Autophagy
, vol.4
, pp. 563-566
-
-
Jin, S.1
White, E.2
-
28
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
PMID: 16148885
-
Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005; 5: 726-34; PMID: 16148885; http://dx. doi. org/10. 1038/nrc1692.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
29
-
-
77951750296
-
Selective autophagy in cancer development and therapy
-
PMID: 20424122
-
Dikic I, Johansen T, Kirkin V. Selective autophagy in cancer development and therapy. Cancer Res 2010; 70: 3431-4; PMID: 20424122; http://dx. doi. org/10. 1158/0008-5472. CAN-09-4027.
-
(2010)
Cancer Res
, vol.70
, pp. 3431-3434
-
-
Dikic, I.1
Johansen, T.2
Kirkin, V.3
-
30
-
-
84870546460
-
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
-
PMID: 23143306
-
Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, et al. ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. J Clin Invest 2012; 122: 4621-34; PMID: 23143306; http://dx. doi. org/10. 1172/JCI62973.
-
(2012)
J Clin Invest
, vol.122
, pp. 4621-4634
-
-
Hart, L.S.1
Cunningham, J.T.2
Datta, T.3
Dey, S.4
Tameire, F.5
Lehman, S.L.6
Qiu, B.7
Zhang, H.8
Cerniglia, G.9
Bi, M.10
-
31
-
-
77955947900
-
Linking ER Stress toAutophagy: Potential Implications for Cancer Therapy
-
PMID: 20145727
-
Verfaillie T, Salazar M, Velasco G, Agostinis P. Linking ER Stress toAutophagy: Potential Implications for Cancer Therapy. Int J Cell Biol 2010; 2010: 930509; PMID: 20145727; http://dx. doi. org/10. 1155/2010/930509.
-
(2010)
Int J Cell Biol
, vol.2010
-
-
Verfaillie, T.1
Salazar, M.2
Velasco, G.3
Agostinis, P.4
-
32
-
-
49949105827
-
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stressinduced autophagy in mammalian cells
-
PMID: 18551133
-
Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS. The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stressinduced autophagy in mammalian cells. Cell Death Differ 2008; 15: 1460-71; PMID: 18551133; http://dx. doi. org/10. 1038/cdd. 2008. 81.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1460-1471
-
-
Li, J.1
Ni, M.2
Lee, B.3
Barron, E.4
Hinton, D.R.5
Lee, A.S.6
-
33
-
-
40849137670
-
The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human Bcells is dependent on the mode of action of specific stresses
-
PMID: 18201741
-
Muscarella DE, Bloom SE. The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human Bcells is dependent on the mode of action of specific stresses. Toxicol Appl Pharmacol 2008; 228: 93-104; PMID: 18201741; http://dx. doi. org/10. 1016/j. taap. 2007. 11. 032.
-
(2008)
Toxicol Appl Pharmacol
, vol.228
, pp. 93-104
-
-
Muscarella, D.E.1
Bloom, S.E.2
-
34
-
-
0033499801
-
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M
-
PMID: 10567572
-
Yamamoto K, Ichijo H, Korsmeyer SJ. BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol Cell Biol 1999; 19: 8469-78; PMID: 10567572.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8469-8478
-
-
Yamamoto, K.1
Ichijo, H.2
Korsmeyer, S.J.3
-
35
-
-
84864942148
-
Bim inhibits autophagy by recruiting Beclin 1 to microtubules
-
PMID: 22742832
-
Luo S, Garcia-Arencibia M, Zhao R, Puri C, Toh PP, Sadiq O, Rubinsztein DC. Bim inhibits autophagy by recruiting Beclin 1 to microtubules. Mol Cell 2012; 47: 359-70; PMID: 22742832; http://dx. doi. org/10. 1016/j. molcel. 2012. 05. 040.
-
(2012)
Mol Cell
, vol.47
, pp. 359-370
-
-
Luo, S.1
Garcia-Arencibia, M.2
Zhao, R.3
Puri, C.4
Toh, P.P.5
Sadiq, O.6
Rubinsztein, D.C.7
-
36
-
-
61849102389
-
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy
-
PMID: 19180116
-
Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. EMBO Rep 2009; 10: 285-92; PMID: 19180116; http://dx. doi. org/10. 1038/embor. 2008. 246.
-
(2009)
EMBO Rep
, vol.10
, pp. 285-292
-
-
Zalckvar, E.1
Berissi, H.2
Mizrachy, L.3
Idelchuk, Y.4
Koren, I.5
Eisenstein, M.6
Sabanay, H.7
Pinkas-Kramarski, R.8
Kimchi, A.9
-
37
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
PMID: 16179260
-
Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD, Levine B. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122: 927-39; PMID: 16179260; http://dx. doi. org/10. 1016/j. cell. 2005. 07. 002.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
38
-
-
84983718691
-
Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells
-
PMID: 23392173
-
Tai WT, Shiau CW, Chen HL, Liu CY, Lin CS, Cheng AL, Chen PJ, Chen KF. Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells. Cell Death Dis 2013; 4: e485; PMID: 23392173; http://dx. doi. org/10. 1038/cddis. 2013. 18.
-
(2013)
Cell Death Dis
, vol.4
-
-
Tai, W.T.1
Shiau, C.W.2
Chen, H.L.3
Liu, C.Y.4
Lin, C.S.5
Cheng, A.L.6
Chen, P.J.7
Chen, K.F.8
-
39
-
-
84892520955
-
HSF1 at a glance
-
PMID: 24421309
-
Vihervaara A, Sistonen L. HSF1 at a glance. J Cell Sci 2014; 127: 261-6; PMID: 24421309; http://dx. doi. org/10. 1242/jcs. 132605.
-
(2014)
J Cell Sci
, vol.127
, pp. 261-266
-
-
Vihervaara, A.1
Sistonen, L.2
-
40
-
-
84864585171
-
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers
-
PMID: 22863008
-
Mendillo ML, Santagata S, Koeva M, Bell GW, Hu R, Tamimi RM, Fraenkel E, Ince TA, Whitesell L, Lindquist S. HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers. Cell 2012; 150: 549-62; PMID: 22863008; http://dx. doi. org/10. 1016/j. cell. 2012. 06. 031.
-
(2012)
Cell
, vol.150
, pp. 549-562
-
-
Mendillo, M.L.1
Santagata, S.2
Koeva, M.3
Bell, G.W.4
Hu, R.5
Tamimi, R.M.6
Fraenkel, E.7
Ince, T.A.8
Whitesell, L.9
Lindquist, S.10
-
41
-
-
0020184673
-
A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene
-
PMID: 6814763
-
Pelham HR. A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene. Cell 1982; 30: 517-28; PMID: 6814763; http://dx. doi. org/10. 1016/0092-8674(82)90249-5.
-
(1982)
Cell
, vol.30
, pp. 517-528
-
-
Pelham, H.R.1
-
42
-
-
18244384703
-
Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress
-
PMID: 15760475
-
Guettouche T, Boellmann F, Lane WS, Voellmy R. Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress. BMC Biochem 2005; 6: 4; PMID: 15760475; http://dx. doi. org/10. 1186/1471-2091-6-4.
-
(2005)
BMC Biochem
, vol.6
, pp. 4
-
-
Guettouche, T.1
Boellmann, F.2
Lane, W.S.3
Voellmy, R.4
-
43
-
-
60149083508
-
Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in humanmelanoma cells
-
PMID: 18842681
-
Jiang CC, Mao ZG, Avery-Kiejda KA, Wade M, Hersey P, Zhang XD. Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in humanmelanoma cells. Carcinogenesis 2009; 30: 197-204; PMID: 18842681; http://dx. doi. org/10. 1093/carcin/bgn220.
-
(2009)
Carcinogenesis
, vol.30
, pp. 197-204
-
-
Jiang, C.C.1
Mao, Z.G.2
Avery-Kiejda, K.A.3
Wade, M.4
Hersey, P.5
Zhang, X.D.6
-
44
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
PMID: 22265414
-
Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 2012; 148: 228-43; PMID: 22265414; http://dx. doi. org/10. 1016/j. cell. 2011. 11. 030.
-
(2012)
Cell
, vol.148
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
45
-
-
56349138968
-
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death
-
PMID: 18806755
-
Gozuacik D, Bialik S, Raveh T, Mitou G, Shohat G, SabanayH, Mizushima N, YoshimoriT, Kimchi A. DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death Differ 2008; 15: 1875-86; PMID: 18806755; http://dx. doi. org/10. 1038/cdd. 2008. 121.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1875-1886
-
-
Gozuacik, D.1
Bialik, S.2
Raveh, T.3
Mitou, G.4
Shohat, G.5
Sabanay, H.6
Mizushima, N.7
Yoshimori, T.8
Kimchi, A.9
-
46
-
-
33947497050
-
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
-
PMID: 17135238
-
Ding WX, Ni HM, Gao W, Hou YF, Melan MA, Chen X, Stolz DB, Shao ZM, Yin XM. Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem 2007; 282: 4702-10; PMID: 17135238; http://dx. doi. org/10. 1074/jbc. M609267200.
-
(2007)
J Biol Chem
, vol.282
, pp. 4702-4710
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Hou, Y.F.4
Melan, M.A.5
Chen, X.6
Stolz, D.B.7
Shao, Z.M.8
Yin, X.M.9
-
47
-
-
77952906975
-
Late phase of the endoplasmic reticulum stress response pathway is regulated by Hog1 MAP kinase
-
PMID: 20382742
-
Bicknell AA, Tourtellotte J, Niwa M. Late phase of the endoplasmic reticulum stress response pathway is regulated by Hog1 MAP kinase. J Biol Chem 2010; 285: 17545-55; PMID: 20382742; http://dx. doi. org/10. 1074/jbc. M109. 084681.
-
(2010)
J Biol Chem
, vol.285
, pp. 17545-17555
-
-
Bicknell, A.A.1
Tourtellotte, J.2
Niwa, M.3
-
48
-
-
53549089861
-
Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
-
PMID: 18769111
-
Wei Y, Sinha S, Levine B. Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation. Autophagy 2008; 4: 949-51; PMID: 18769111; http://dx. doi. org/10. 4161/auto. 6788.
-
(2008)
Autophagy
, vol.4
, pp. 949-951
-
-
Wei, Y.1
Sinha, S.2
Levine, B.3
-
49
-
-
33744800561
-
Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK
-
PMID: 16680093
-
Yang Q, Kim YS, Lin Y, Lewis J, Neckers L, Liu ZG. Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK. EMBORep 2006; 7: 622-7; PMID: 16680093.
-
(2006)
EMBORep
, vol.7
, pp. 622-627
-
-
Yang, Q.1
Kim, Y.S.2
Lin, Y.3
Lewis, J.4
Neckers, L.5
Liu, Z.G.6
-
50
-
-
84902126876
-
A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy
-
PMID: 23831571
-
He W, Wang Q, Srinivasan B, Xu J, Padilla MT, Li Z, Wang X, Liu Y, Gou X, Shen HM, et al. A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy. Oncogene 2014; 33: 3004-13; PMID: 23831571; http://dx. doi. org/10. 1038/onc. 2013. 256.
-
(2014)
Oncogene
, vol.33
, pp. 3004-3013
-
-
He, W.1
Wang, Q.2
Srinivasan, B.3
Xu, J.4
Padilla, M.T.5
Li, Z.6
Wang, X.7
Liu, Y.8
Gou, X.9
Shen, H.M.10
-
51
-
-
79960921946
-
The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
-
PMID: 21737329
-
Tenev T, Bianchi K, Darding M, Broemer M, Langlais C, Wallberg F, Zachariou A, Lopez J, MacFarlane M, Cain K, et al. The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 2011; 43: 432-48; PMID: 21737329; http://dx. doi. org/10. 1016/j. molcel. 2011. 06. 006.
-
(2011)
Mol Cell
, vol.43
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
Broemer, M.4
Langlais, C.5
Wallberg, F.6
Zachariou, A.7
Lopez, J.8
McFarlane, M.9
Cain, K.10
-
52
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
PMID: 18408713
-
Degterev A, Hitomi J, Germscheid M, Ch'en IL, Korkina O, Teng X, Abbott D, Cuny GD, Yuan C, Wagner G, et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 2008; 4: 313-21; PMID: 18408713; http://dx. doi. org/10. 1038/nchembio. 83.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
-
53
-
-
84873669841
-
HepatitisCvirus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy
-
PMID: 23169238
-
Huang H, Kang R, Wang J, Luo G, Yang W, Zhao Z. HepatitisCvirus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy. Autophagy 2013; 9: 175-95; PMID: 23169238; http://dx. doi. org/10. 4161/auto. 22791.
-
(2013)
Autophagy
, vol.9
, pp. 175-195
-
-
Huang, H.1
Kang, R.2
Wang, J.3
Luo, G.4
Yang, W.5
Zhao, Z.6
-
54
-
-
33846189759
-
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2
-
PMID: 17244528
-
Hoyer-Hansen M, Bastholm L, Szyniarowski P, Campanella M, Szabadkai G, Farkas T, Bianchi K, Fehrenbacher N, Elling F, Rizzuto R, et al. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol Cell 2007; 25: 193-205; PMID: 17244528; http://dx. doi. org/10. 1016/j. molcel. 2006. 12. 009.
-
(2007)
Mol Cell
, vol.25
, pp. 193-205
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Szyniarowski, P.3
Campanella, M.4
Szabadkai, G.5
Farkas, T.6
Bianchi, K.7
Fehrenbacher, N.8
Elling, F.9
Rizzuto, R.10
-
55
-
-
22244446505
-
The mammalian unfolded protein response
-
PMID: 15952902
-
Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem 2005; 74: 739-89; PMID: 15952902; http://dx. doi. org/10. 1146/annurev. biochem. 73. 011303. 074134.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
56
-
-
84872728523
-
Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress
-
PMID: 23192351
-
Dai B, Gong A, Jing Z, Aldape KD, Kang SH, Sawaya R, Huang S. Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress. J Biol Chem 2013; 288: 1634-42; PMID: 23192351; http://dx. doi. org/10. 1074/jbc. M112. 379362.
-
(2013)
J Biol Chem
, vol.288
, pp. 1634-1642
-
-
Dai, B.1
Gong, A.2
Jing, Z.3
Aldape, K.D.4
Kang, S.H.5
Sawaya, R.6
Huang, S.7
-
57
-
-
0033229880
-
HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice
-
PMID: 10545106
-
Xiao X, Zuo X, Davis AA, McMillan DR, Curry BB, Richardson JA, Benjamin IJ. HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice. EMBO J 1999; 18: 5943-52; PMID: 10545106; http://dx. doi. org/10. 1093/emboj/18. 21. 5943.
-
(1999)
EMBO J
, vol.18
, pp. 5943-5952
-
-
Xiao, X.1
Zuo, X.2
Davis, A.A.3
McMillan, D.R.4
Curry, B.B.5
Richardson, J.A.6
Benjamin, I.J.7
-
58
-
-
84867152376
-
Loss of tumor suppressor NF1 activatesHSF1 to promote carcinogenesis
-
PMID: 22945628
-
Dai C, Santagata S, Tang Z, Shi J, Cao J, Kwon H, Bronson RT, Whitesell L, Lindquist S. Loss of tumor suppressor NF1 activatesHSF1 to promote carcinogenesis. J Clin Invest 2012; 122: 3742-54; PMID: 22945628; http://dx. doi. org/10. 1172/JCI62727.
-
(2012)
J Clin Invest
, vol.122
, pp. 3742-3754
-
-
Dai, C.1
Santagata, S.2
Tang, Z.3
Shi, J.4
Cao, J.5
Kwon, H.6
Bronson, R.T.7
Whitesell, L.8
Lindquist, S.9
-
59
-
-
79953282304
-
NEMO and RIP1 control cell fate in response to extensive DNA damage via TNFalpha feedforward signaling
-
PMID: 21458669
-
Biton S, Ashkenazi A. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNFalpha feedforward signaling. Cell 2011; 145: 92-103; PMID: 21458669; http://dx. doi. org/10. 1016/j. cell. 2011. 02. 023.
-
(2011)
Cell
, vol.145
, pp. 92-103
-
-
Biton, S.1
Ashkenazi, A.2
-
60
-
-
66149128126
-
The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma
-
PMID: 19339267
-
Park S, Hatanpaa KJ, Xie Y, Mickey BE, Madden CJ, Raisanen JM, Ramnarain DB, Xiao G, Saha D, Boothman DA, et al. The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma. Cancer Res 2009; 69: 2809-16; PMID: 19339267; http://dx. doi. org/10. 1158/0008-5472. CAN-08-4079.
-
(2009)
Cancer Res
, vol.69
, pp. 2809-2816
-
-
Park, S.1
Hatanpaa, K.J.2
Xie, Y.3
Mickey, B.E.4
Madden, C.J.5
Raisanen, J.M.6
Ramnarain, D.B.7
Xiao, G.8
Saha, D.9
Boothman, D.A.10
-
61
-
-
43549087613
-
Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma
-
PMID: 18476909
-
Hersey P, Zhang XD. Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma. Pigment Cell Melanoma Res 2008; 21: 358-67; PMID: 18476909; http://dx. doi. org/10. 1111/j. 1755-148X. 2008. 00467. x.
-
(2008)
Pigment Cell Melanoma Res
, vol.21
, pp. 358-367
-
-
Hersey, P.1
Zhang, X.D.2
-
62
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
-
PMID: 9529147
-
Kelliher MA, Grimm S, Ishida Y, Kuo F, Stanger BZ, Leder P. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 1998; 8: 297-303; PMID: 9529147; http://dx. doi. org/10. 1016/S1074-7613(00)80535-X.
-
(1998)
Immunity
, vol.8
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
63
-
-
0035912094
-
Repression of GADD153/CHOP by NF-kappaB: A possible cellular defense against endoplasmic reticulum stress-induced cell death
-
PMID: 11360202
-
Nozaki S, Sledge Jr GW, Nakshatri H. Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death. Oncogene 2001; 20: 2178-85; PMID: 11360202; http://dx. doi. org/10. 1038/sj. onc. 1204292.
-
(2001)
Oncogene
, vol.20
, pp. 2178-2185
-
-
Nozaki, S.1
Sledge Jr, G.W.2
Nakshatri, H.3
-
64
-
-
34248998801
-
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
-
PMID: 17446862
-
Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, Tasdemir E, Pierron G, Troulinaki K, Tavernarakis N, et al. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 2007; 26: 2527-39; PMID: 17446862; http://dx. doi. org/10. 1038/sj. emboj. 7601689.
-
(2007)
EMBO J
, vol.26
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
Rain, J.C.4
Gautier, F.5
Juin, P.6
Tasdemir, E.7
Pierron, G.8
Troulinaki, K.9
Tavernarakis, N.10
-
65
-
-
34249037565
-
Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
-
PMID: 17337444
-
Oberstein A, Jeffrey PD, Shi Y. Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J Biol Chem 2007; 282: 13123-32; PMID: 17337444; http://dx. doi. org/10. 1074/jbc. M700492200.
-
(2007)
J Biol Chem
, vol.282
, pp. 13123-13132
-
-
Oberstein, A.1
Jeffrey, P.D.2
Shi, Y.3
-
66
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
PMID: 11410528
-
Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001; 15: 1481-6; PMID: 11410528; http://dx. doi. org/10. 1101/gad. 897601.
-
(2001)
Genes Dev
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
McGregor, G.R.4
Thompson, C.B.5
-
67
-
-
68549089038
-
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins
-
PMID: 19651893
-
Merino D, Giam M, Hughes PD, Siggs OM, Heger K, O'Reilly LA, Adams JM, Strasser A, Lee EF, Fairlie WD, et al. The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins. J Cell Biol 2009; 186: 355-62; PMID: 19651893; http://dx. doi. org/10. 1083/jcb. 200905153.
-
(2009)
J Cell Biol
, vol.186
, pp. 355-362
-
-
Merino, D.1
Giam, M.2
Hughes, P.D.3
Siggs, O.M.4
Heger, K.5
O'Reilly, L.A.6
Adams, J.M.7
Strasser, A.8
Lee, E.F.9
Fairlie, W.D.10
-
68
-
-
43449132366
-
Multisite phosphorylation regulates Bim stability and apoptotic activity
-
PMID: 18498746
-
Hubner A, Barrett T, Flavell RA, Davis RJ. Multisite phosphorylation regulates Bim stability and apoptotic activity. Mol Cell 2008; 30: 415-25; PMID: 18498746; http://dx. doi. org/10. 1016/j. molcel. 2008. 03. 025.
-
(2008)
Mol Cell
, vol.30
, pp. 415-425
-
-
Hubner, A.1
Barrett, T.2
Flavell, R.A.3
Davis, R.J.4
-
69
-
-
0038482050
-
Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
-
PMID: 12646560
-
Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 2003; 278: 18811-6; PMID: 12646560; http://dx. doi. org/10. 1074/jbc. M301010200.
-
(2003)
J Biol Chem
, vol.278
, pp. 18811-18816
-
-
Ley, R.1
Balmanno, K.2
Hadfield, K.3
Weston, C.4
Cook, S.J.5
-
70
-
-
84863442225
-
Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress
-
PMID: 22739989
-
Tay KH, Jin L, Tseng HY, Jiang CC, Ye Y, Thorne RF, Liu T, Guo ST, Verrills NM, Hersey P, et al. Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress. Cell Death Dis 2012; 3: e337; PMID: 22739989; http://dx. doi. org/10. 1038/cddis. 2012. 79.
-
(2012)
Cell Death Dis
, vol.3
-
-
Tay, K.H.1
Jin, L.2
Tseng, H.Y.3
Jiang, C.C.4
Ye, Y.5
Thorne, R.F.6
Liu, T.7
Guo, S.T.8
Verrills, N.M.9
Hersey, P.10
-
71
-
-
73649089980
-
ERK and cell death: Mechanisms of ERK-induced cell death-apoptosis, autophagy and senescence
-
PMID: 19843174
-
Cagnol S, Chambard JC. ERK and cell death: mechanisms of ERK-induced cell death-apoptosis, autophagy and senescence. FEBS J 2010; 277: 2-21; PMID: 19843174; http://dx. doi. org/10. 1111/j. 1742-4658. 2009. 07366. x.
-
(2010)
FEBS J
, vol.277
, pp. 2-21
-
-
Cagnol, S.1
Chambard, J.C.2
-
72
-
-
31544461235
-
Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells
-
PMID: 16113053
-
Ellington AA, Berhow MA, Singletary KW. Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells. Carcinogenesis 2006; 27: 298-306; PMID: 16113053; http://dx. doi. org/10. 1093/carcin/bgi214.
-
(2006)
Carcinogenesis
, vol.27
, pp. 298-306
-
-
Ellington, A.A.1
Berhow, M.A.2
Singletary, K.W.3
-
73
-
-
49549123183
-
Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factoralpha-induced cell death in MCF-7 cells
-
PMID: 18266953
-
Sivaprasad U, Basu A. Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factoralpha-induced cell death in MCF-7 cells. J Cell Mol Med 2008; 12: 1265-71; PMID: 18266953; http://dx. doi. org/10. 1111/j. 1582-4934. 2008. 00282. x.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 1265-1271
-
-
Sivaprasad, U.1
Basu, A.2
-
74
-
-
77950912075
-
p38 Mitogen-activated protein kinase is involved in endoplasmic reticulum stressinduced cell death and autophagy in human gingival fibroblasts
-
PMID: 20410583
-
Kim DS, Kim JH, Lee GH, Kim HT, Lim JM, Chae SW, Chae HJ, Kim HR. p38 Mitogen-activated protein kinase is involved in endoplasmic reticulum stressinduced cell death and autophagy in human gingival fibroblasts. Biol Pharm Bull 2010; 33: 545-9; PMID: 20410583; http://dx. doi. org/10. 1248/bpb. 33. 545.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 545-549
-
-
Kim, D.S.1
Kim, J.H.2
Lee, G.H.3
Kim, H.T.4
Lim, J.M.5
Chae, S.W.6
Chae, H.J.7
Kim, H.R.8
-
75
-
-
84903833678
-
Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells
-
PMID: 24905917
-
Zhong W, Zhu H, Sheng F, Tian Y, Zhou J, Chen Y, Li S, Lin J. Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells. Autophagy 2014; 10: 1285-300; PMID: 24905917; http://dx. doi. org/10. 4161/auto. 28789.
-
(2014)
Autophagy
, vol.10
, pp. 1285-1300
-
-
Zhong, W.1
Zhu, H.2
Sheng, F.3
Tian, Y.4
Zhou, J.5
Chen, Y.6
Li, S.7
Lin, J.8
-
76
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
PMID: 21364565
-
Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol 2011; 13: 184-90; PMID: 21364565; http://dx. doi. org/10. 1038/ncb0311-184.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
77
-
-
0038433303
-
JunD mediates survival signaling by the JNK signal transduction pathway
-
PMID: 12820962
-
Lamb JA, Ventura JJ, Hess P, Flavell RA, Davis RJ. JunD mediates survival signaling by the JNK signal transduction pathway. Mol Cell 2003; 11: 1479-89; PMID: 12820962; http://dx. doi. org/10. 1016/S1097-2765(03)00203-X.
-
(2003)
Mol Cell
, vol.11
, pp. 1479-1489
-
-
Lamb, J.A.1
Ventura, J.J.2
Hess, P.3
Flavell, R.A.4
Davis, R.J.5
-
78
-
-
1242316958
-
JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD
-
PMID: 14967141
-
Yu C, Minemoto Y, Zhang J, Liu J, Tang F, Bui TN, Xiang J, Lin A. JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Mol Cell 2004; 13: 329-40; PMID: 14967141; http://dx. doi. org/10. 1016/S1097-2765(04)00028-0.
-
(2004)
Mol Cell
, vol.13
, pp. 329-340
-
-
Yu, C.1
Minemoto, Y.2
Zhang, J.3
Liu, J.4
Tang, F.5
Bui, T.N.6
Xiang, J.7
Lin, A.8
-
79
-
-
84904122732
-
High level of HSF1 associates with aggressive endometrial carcinoma and suggests potential for HSP90 inhibitors
-
PMID: 24853175
-
Engerud H, Tangen IL, Berg A, Kusonmano K, Halle MK, Oyan AM, Kalland KH, Stefansson I, Trovik J, Salvesen HB, et al. High level of HSF1 associates with aggressive endometrial carcinoma and suggests potential for HSP90 inhibitors. Br J Cancer 2014; 111: 78-84; PMID: 24853175; http://dx. doi. org/10. 1038/bjc. 2014. 262.
-
(2014)
Br J Cancer
, vol.111
, pp. 78-84
-
-
Engerud, H.1
Tangen, I.L.2
Berg, A.3
Kusonmano, K.4
Halle, M.K.5
Oyan, A.M.6
Kalland, K.H.7
Stefansson, I.8
Trovik, J.9
Salvesen, H.B.10
-
80
-
-
81055141345
-
High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer
-
PMID: 22042860
-
Santagata S, Hu R, Lin NU, Mendillo ML, Collins LC, Hankinson SE, Schnitt SJ, Whitesell L, Tamimi RM, Lindquist S, et al. High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer. Proc Natl Acad Sci U S A 2011; 108: 18378-83; PMID: 22042860; http://dx. doi. org/10. 1073/pnas. 1115031108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 18378-18383
-
-
Santagata, S.1
Hu, R.2
Lin, N.U.3
Mendillo, M.L.4
Collins, L.C.5
Hankinson, S.E.6
Schnitt, S.J.7
Whitesell, L.8
Tamimi, R.M.9
Lindquist, S.10
-
81
-
-
34250888209
-
Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligandinduced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response
-
PMID: 17575157
-
Jiang CC, Chen LH, Gillespie S, Kiejda KA, Mhaidat N, Wang YF, Thorne R, Zhang XD, Hersey P. Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligandinduced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response. Cancer Res 2007; 67: 5880-8; PMID: 17575157; http://dx. doi. org/10. 1158/0008-5472. CAN-07-0213.
-
(2007)
Cancer Res
, vol.67
, pp. 5880-5888
-
-
Jiang, C.C.1
Chen, L.H.2
Gillespie, S.3
Kiejda, K.A.4
Mhaidat, N.5
Wang, Y.F.6
Thorne, R.7
Zhang, X.D.8
Hersey, P.9
-
82
-
-
0038446405
-
The unfolded protein response
-
PMID: 12692187
-
Liu CY, Kaufman RJ. The unfolded protein response. J Cell Sci 2003; 116: 1861-2; PMID: 12692187; http://dx. doi. org/10. 1242/jcs. 00408.
-
(2003)
J Cell Sci
, vol.116
, pp. 1861-1862
-
-
Liu, C.Y.1
Kaufman, R.J.2
-
83
-
-
78650439014
-
Contrasting effects of nutlin-3 on TRAIL-and docetaxel-induced apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells
-
PMID: 21159614
-
Tseng HY, Jiang CC, Croft A, Tay KH, Thorne RF, Yang F, Liu H, Hersey P, Zhang XD. Contrasting effects of nutlin-3 on TRAIL-and docetaxel-induced apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells. Mol Cancer Ther 2010; 9: 3363-74; PMID: 21159614; http://dx. doi. org/10. 1158/1535-7163. MCT-10-0646.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 3363-3374
-
-
Tseng, H.Y.1
Jiang, C.C.2
Croft, A.3
Tay, K.H.4
Thorne, R.F.5
Yang, F.6
Liu, H.7
Hersey, P.8
Zhang, X.D.9
-
84
-
-
84879668461
-
Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3
-
PMID: 23744355
-
Lai F, Guo ST, Jin L, Jiang CC, Wang CY, Croft A, Chi MN, Tseng HY, Farrelly M, Atmadibrata B, et al. Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3. Cell Death Dis 2013; 4: e655; PMID: 23744355; http://dx. doi. org/10. 1038/cddis. 2013. 192.
-
(2013)
Cell Death Dis
, vol.4
-
-
Lai, F.1
Guo, S.T.2
Jin, L.3
Jiang, C.C.4
Wang, C.Y.5
Croft, A.6
Chi, M.N.7
Tseng, H.Y.8
Farrelly, M.9
Atmadibrata, B.10
-
85
-
-
84874634909
-
PI(4, 5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma
-
PMID: 23443536
-
Ye Y, Jin L, Wilmott JS, Hu WL, Yosufi B, Thorne RF, Liu T, Rizos H, Yan XG, Dong L, et al. PI(4, 5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma. Nat Commun 2013; 4: 1508; PMID: 23443536; http://dx. doi. org/10. 1038/ncomms2489.
-
(2013)
Nat Commun
, vol.4
, pp. 1508
-
-
Ye, Y.1
Jin, L.2
Wilmott, J.S.3
Hu, W.L.4
Yosufi, B.5
Thorne, R.F.6
Liu, T.7
Rizos, H.8
Yan, X.G.9
Dong, L.10
-
86
-
-
77954658690
-
Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cells
-
PMID: 20300110
-
Yang F, Tay KH, Dong L, Thorne RF, Jiang CC, Yang E, Tseng HY, Liu H, Christopherson R, Hersey P, et al. Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cells. Cell Death Differ 2010; 17: 1354-67; PMID: 20300110; http://dx. doi. org/10. 1038/cdd. 2010. 29.
-
(2010)
Cell Death Differ
, vol.17
, pp. 1354-1367
-
-
Yang, F.1
Tay, K.H.2
Dong, L.3
Thorne, R.F.4
Jiang, C.C.5
Yang, E.6
Tseng, H.Y.7
Liu, H.8
Christopherson, R.9
Hersey, P.10
|