Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cells

Cell Death and Differentiation

Volumn 17, Issue 8, 2010, Pages 1354-1367

  Yang, F ^a   Tay, K H ^a   Dong, L ^a   Thorne, R F ^a   Jiang, C C ^a   Yang, E ^b   Tseng, H Y ^a   Liu, H ^a   Christopherson, R ^b   Hersey, P ^a   Zhang, X D ^a  

^a CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CATHEPSIN B; CATHEPSIN L; CYSTATIN B; CYSTEINE PROTEINASE; FLICE INHIBITORY PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UBIQUITIN PROTEIN LIGASE E3; ITCH PROTEIN, HUMAN; REPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE OVEREXPRESSION; HALF LIFE TIME; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; SENSITIZATION; UBIQUITINATION; ENZYMOLOGY; GENE SILENCING; GENETICS; MELANOMA; METABOLISM; RNA INTERFERENCE; TUMOR CELL LINE;

APOPTOSIS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CELL LINE, TUMOR; CYSTATIN B; GENE KNOCKDOWN TECHNIQUES; HUMANS; MELANOMA; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TNF-RELATED APOPTOSIS-INDUCING LIGAND; UBIQUITIN-PROTEIN LIGASES;

EID: 77954658690     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.29     Document Type: Article

References (0)