A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy

Oncogene

Volumn 33, Issue 23, 2014, Pages 3004-3013

  He, W ^a,b   Wang, Q ^a,c   Srinivasan, B ^d   Xu, J ^a   Padilla, M T ^a   Li, Z ^a   Wang, X ^c   Liu, Y ^a   Gou, X ^b   Shen, H M ^e   Xing, C ^d   Lin, Y ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

^d UNIVERSITY OF MINNESOTA   (United States)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

apoptosis; autophagy; c IAP; necroptosis; RIP1; RIP3

Indexed keywords

BECLIN 1; CASPASE; CELLULAR INHIBITOR OF APOPTOSIS 1 PROTEIN; CHALCONE 24; CHALCONE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; NECROSTATIN 1; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; RIP1 KINASE; RIP3 KINASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER CHEMOTHERAPY; CELL DEATH; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DISSOCIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NECROPTOSIS; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; CHALCONES; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMIDAZOLES; INDOLES; INHIBITOR OF APOPTOSIS PROTEINS; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; NUCLEAR PORE COMPLEX PROTEINS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; UBIQUITIN-ACTIVATING ENZYMES;

EID: 84902126876     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.256     Document Type: Article

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