Increased mitochondrial oxidative damage and oxidative DNA damage contributes to the neurodegenerative process in sporadic amyotrophic lateral sclerosis

Free Radical Research

Volumn 42, Issue 3, 2008, Pages 221-225

  Murata, Takahiko ^a,b   Ohtsuka, Chigumi ^b   Terayama, Yasuo ^b  

^a Iwate Prefectural Ninohe Public Health Center   (Japan)

^b IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

8 hydroxy 2 deoxyguanosine; Cerebrospinal fluid; Coenzyme Q10; Sporadic amyotrophic lateral sclerosis

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DNA; UBIDECARENONE;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN MITOCHONDRION; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE DURATION; DISEASE SEVERITY; DNA DAMAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; OXIDATION; PATHOGENESIS; RATING SCALE;

AGED; AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; CASE-CONTROL STUDIES; CHROMATOGRAPHY; DEOXYGUANOSINE; DNA DAMAGE; HUMANS; MIDDLE AGED; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXYGEN; TIME FACTORS;

EID: 41049090802     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760701877262     Document Type: Article

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