-
1
-
-
84900467984
-
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 env trimers
-
Blattner C., Lee J., Sliepen K., Derking R., Falkowska E., de la Peña A., Cupo A., Julien J.-P., van Gils M.J., Lee P.S., Peng W., Paulson J.C., Poignard P., Burton D.R., Moore J.P., Sanders R.W., Wilson I.A., Ward A.B. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 env trimers. Immunity 2014, 40:669-680. 10.1016/j.immuni.2014.04.008.
-
(2014)
Immunity
, vol.40
, pp. 669-680
-
-
Blattner, C.1
Lee, J.2
Sliepen, K.3
Derking, R.4
Falkowska, E.5
de la Peña, A.6
Cupo, A.7
Julien, J.-P.8
van Gils, M.J.9
Lee, P.S.10
Peng, W.11
Paulson, J.C.12
Poignard, P.13
Burton, D.R.14
Moore, J.P.15
Sanders, R.W.16
Wilson, I.A.17
Ward, A.B.18
-
2
-
-
80052938385
-
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
-
Bonsignori M., Hwang K.-K., Chen X., Tsao C.-Y., Morris L., Gray E., Marshall D.J., Crump J.A., Kapiga S.H., Sam N.E., Sinangil F., Pancera M., Yongping Y., Zhang B., Zhu J., Kwong P.D., O'Dell S., Mascola J.R., Wu L., Nabel G.J., Phogat S., Seaman M.S., Whitesides J.F., Moody M.A., Kelsoe G., Yang X., Sodroski J., Shaw G.M., Montefiori D.C., Kepler T.B., Tomaras G.D., Alam S.M., Liao H.-X., Haynes B.F. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. J. Virol. 2011, 85:9998-10009. 10.1128/JVI.05045-11.
-
(2011)
J. Virol.
, vol.85
, pp. 9998-10009
-
-
Bonsignori, M.1
Hwang, K.-K.2
Chen, X.3
Tsao, C.-Y.4
Morris, L.5
Gray, E.6
Marshall, D.J.7
Crump, J.A.8
Kapiga, S.H.9
Sam, N.E.10
Sinangil, F.11
Pancera, M.12
Yongping, Y.13
Zhang, B.14
Zhu, J.15
Kwong, P.D.16
O'Dell, S.17
Mascola, J.R.18
Wu, L.19
Nabel, G.J.20
Phogat, S.21
Seaman, M.S.22
Whitesides, J.F.23
Moody, M.A.24
Kelsoe, G.25
Yang, X.26
Sodroski, J.27
Shaw, G.M.28
Montefiori, D.C.29
Kepler, T.B.30
Tomaras, G.D.31
Alam, S.M.32
Liao, H.-X.33
Haynes, B.F.34
more..
-
3
-
-
84899991983
-
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
-
Doria-Rose N.A., Schramm C.A., Gorman J., Moore P.L., Bhiman J.N., DeKosky B.J., Ernandes M.J., Georgiev I.S., Kim H.J., Pancera M., Staupe R.P., Altae-Tran H.R., Bailer R.T., Crooks E.T., Cupo A., Druz A., Garrett N.J., Hoi K.H., Kong R., Louder M.K., Longo N.S., McKee K., Nonyane M., O'Dell S., Roark R.S., Rudicell R.S., Schmidt S.D., Sheward D.J., Soto C., Wibmer C.K., Yang Y., Zhang Z., Mullikin J.C., Binley J.M., Sanders R.W., Wilson I.A., Moore J.P., Ward A.B., Georgiou G., Williamson C., Abdool Karim S.S., Morris L., Kwong P.D., Shapiro L., Mascola J.R. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature 2014, 509:55-62. 10.1038/nature13036.
-
(2014)
Nature
, vol.509
, pp. 55-62
-
-
Doria-Rose, N.A.1
Schramm, C.A.2
Gorman, J.3
Moore, P.L.4
Bhiman, J.N.5
DeKosky, B.J.6
Ernandes, M.J.7
Georgiev, I.S.8
Kim, H.J.9
Pancera, M.10
Staupe, R.P.11
Altae-Tran, H.R.12
Bailer, R.T.13
Crooks, E.T.14
Cupo, A.15
Druz, A.16
Garrett, N.J.17
Hoi, K.H.18
Kong, R.19
Louder, M.K.20
Longo, N.S.21
McKee, K.22
Nonyane, M.23
O'Dell, S.24
Roark, R.S.25
Rudicell, R.S.26
Schmidt, S.D.27
Sheward, D.J.28
Soto, C.29
Wibmer, C.K.30
Yang, Y.31
Zhang, Z.32
Mullikin, J.C.33
Binley, J.M.34
Sanders, R.W.35
Wilson, I.A.36
Moore, J.P.37
Ward, A.B.38
Georgiou, G.39
Williamson, C.40
Abdool Karim, S.S.41
Morris, L.42
Kwong, P.D.43
Shapiro, L.44
Mascola, J.R.45
more..
-
4
-
-
84934937791
-
Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice
-
Dosenovic P., von Boehmer L., Escolano A., Jardine J., Freund N.T., Gitlin A.D., McGuire A.T., Kulp D.W., Oliveira T., Scharf L., Pietzsch J., Gray M.D., Cupo A., van Gils M.J., Yao K.-H., Liu C., Gazumyan A., Seaman M.S., Björkman P.J., Sanders R.W., Moore J.P., Stamatatos L., Schief W.R., Nussenzweig M.C. Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice. Cell 2015, 161:1505-1515. 10.1016/j.cell.2015.06.003.
-
(2015)
Cell
, vol.161
, pp. 1505-1515
-
-
Dosenovic, P.1
von Boehmer, L.2
Escolano, A.3
Jardine, J.4
Freund, N.T.5
Gitlin, A.D.6
McGuire, A.T.7
Kulp, D.W.8
Oliveira, T.9
Scharf, L.10
Pietzsch, J.11
Gray, M.D.12
Cupo, A.13
van Gils, M.J.14
Yao, K.-H.15
Liu, C.16
Gazumyan, A.17
Seaman, M.S.18
Björkman, P.J.19
Sanders, R.W.20
Moore, J.P.21
Stamatatos, L.22
Schief, W.R.23
Nussenzweig, M.C.24
more..
-
5
-
-
3242876679
-
IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis
-
Giudicelli V., Chaume D., Lefranc M.P. IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis. Nucleic Acids Res. 2004, 32:435-440. 10.1093/nar/gkh412.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 435-440
-
-
Giudicelli, V.1
Chaume, D.2
Lefranc, M.P.3
-
6
-
-
84860759632
-
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
-
Haynes B.F., Kelsoe G., Harrison S.C., Kepler T.B. B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nat. Biotechnol. 2012, 30:423-433. 10.1038/nbt.2197.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 423-433
-
-
Haynes, B.F.1
Kelsoe, G.2
Harrison, S.C.3
Kepler, T.B.4
-
7
-
-
84877350114
-
Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes
-
Hoffenberg S., Powell R., Carpov A., Wagner D., Wilson A., Kosakovsky Pond S., Lindsay R., Arendt H., Destefano J., Phogat S., Poignard P., Fling S.P., Simek M., Labranche C., Montefiori D., Wrin T., Phung P., Burton D., Koff W., King C.R., Parks C.L., Caulfield M.J. Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes. J. Virol. 2013, 87:5372-5383. 10.1128/JVI.02827-12.
-
(2013)
J. Virol.
, vol.87
, pp. 5372-5383
-
-
Hoffenberg, S.1
Powell, R.2
Carpov, A.3
Wagner, D.4
Wilson, A.5
Kosakovsky Pond, S.6
Lindsay, R.7
Arendt, H.8
Destefano, J.9
Phogat, S.10
Poignard, P.11
Fling, S.P.12
Simek, M.13
Labranche, C.14
Montefiori, D.15
Wrin, T.16
Phung, P.17
Burton, D.18
Koff, W.19
King, C.R.20
Parks, C.L.21
Caulfield, M.J.22
more..
-
8
-
-
84875061923
-
Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs
-
Hoot S., McGuire A.T., Cohen K.W., Strong R.K., Hangartner L., Klein F., Diskin R., Scheid J.F., Sather D.N., Burton D.R., Stamatatos L. Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs. PLoS Pathog. 2013, 9:e1003106. 10.1371/journal.ppat.1003106.
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003106
-
-
Hoot, S.1
McGuire, A.T.2
Cohen, K.W.3
Strong, R.K.4
Hangartner, L.5
Klein, F.6
Diskin, R.7
Scheid, J.F.8
Sather, D.N.9
Burton, D.R.10
Stamatatos, L.11
-
9
-
-
84921607768
-
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface
-
Huang J., Kang B.H., Pancera M., Lee J.H., Tong T., Feng Y., Imamichi H., Georgiev I.S., Chuang G.-Y., Druz A., Doria-Rose N.A., Laub L., Sliepen K., van Gils M.J., de la Peña A.T., Derking R., Klasse P.J., Migueles S.A., Bailer R.T., Alam M., Pugach P., Haynes B.F., Wyatt R.T., Sanders R.W., Binley J.M., Ward A.B., Mascola J.R., Kwong P.D., Connors M. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature 2014, 515:138-142. 10.1038/nature13601.
-
(2014)
Nature
, vol.515
, pp. 138-142
-
-
Huang, J.1
Kang, B.H.2
Pancera, M.3
Lee, J.H.4
Tong, T.5
Feng, Y.6
Imamichi, H.7
Georgiev, I.S.8
Chuang, G.-Y.9
Druz, A.10
Doria-Rose, N.A.11
Laub, L.12
Sliepen, K.13
van Gils, M.J.14
de la Peña, A.T.15
Derking, R.16
Klasse, P.J.17
Migueles, S.A.18
Bailer, R.T.19
Alam, M.20
Pugach, P.21
Haynes, B.F.22
Wyatt, R.T.23
Sanders, R.W.24
Binley, J.M.25
Ward, A.B.26
Mascola, J.R.27
Kwong, P.D.28
Connors, M.29
more..
-
10
-
-
84877609579
-
Rational HIV immunogen design to target specific germline B cell receptors
-
Jardine J., Julien J.-P., Menis S., Ota T., Kalyuzhniy O., McGuire A., Sok D., Huang P.-S., MacPherson S., Jones M., Nieusma T., Mathison J., Baker D., Ward A.B., Burton D.R., Stamatatos L., Nemazee D., Wilson I.A., Schief W.R. Rational HIV immunogen design to target specific germline B cell receptors. Science 2013, 340:711-716. 10.1126/science.1234150.
-
(2013)
Science
, vol.340
, pp. 711-716
-
-
Jardine, J.1
Julien, J.-P.2
Menis, S.3
Ota, T.4
Kalyuzhniy, O.5
McGuire, A.6
Sok, D.7
Huang, P.-S.8
MacPherson, S.9
Jones, M.10
Nieusma, T.11
Mathison, J.12
Baker, D.13
Ward, A.B.14
Burton, D.R.15
Stamatatos, L.16
Nemazee, D.17
Wilson, I.A.18
Schief, W.R.19
-
11
-
-
84934954773
-
Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen
-
Jardine J.G., Ota T., Sok D., Pauthner M., Kulp D.W., Kalyuzhniy O., Skog P.D., Thinnes T.C., Bhullar D., Briney B., Menis S., Jones M., Kubitz M., Spencer S., Adachi Y., Burton D.R., Schief W.R., Nemazee D. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. Science 2015, 80:1-12. 10.1126/science.aac5894.
-
(2015)
Science
, vol.80
, pp. 1-12
-
-
Jardine, J.G.1
Ota, T.2
Sok, D.3
Pauthner, M.4
Kulp, D.W.5
Kalyuzhniy, O.6
Skog, P.D.7
Thinnes, T.C.8
Bhullar, D.9
Briney, B.10
Menis, S.11
Jones, M.12
Kubitz, M.13
Spencer, S.14
Adachi, Y.15
Burton, D.R.16
Schief, W.R.17
Nemazee, D.18
-
12
-
-
84942856317
-
Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens
-
Julien J.-P., Lee J.H., Ozorowski G., Hua Y., de la Peña A.T., de Taeye S.W., Nieusma T., Cupo A., Yasmeen A., Golabek M., Pugach P., Klasse P.J., Moore J.P., Sanders R.W., Ward A.B., Wilson I.A. Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens. Proc. Natl. Acad. Sci. USA. 2015, 112:11947-11952. 10.1073/pnas.1507793112.
-
(2015)
Proc. Natl. Acad. Sci. USA.
, vol.112
, pp. 11947-11952
-
-
Julien, J.-P.1
Lee, J.H.2
Ozorowski, G.3
Hua, Y.4
de la Peña, A.T.5
de Taeye, S.W.6
Nieusma, T.7
Cupo, A.8
Yasmeen, A.9
Golabek, M.10
Pugach, P.11
Klasse, P.J.12
Moore, J.P.13
Sanders, R.W.14
Ward, A.B.15
Wilson, I.A.16
-
13
-
-
84875034460
-
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
-
Julien J.-P., Lee J.H., Cupo A., Murin C.D., Derking R., Hoffenberg S., Caulfield M.J., King C.R., Marozsan A.J., Klasse P.J., Sanders R.W., Moore J.P., Wilson I.A., Ward A.B. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proc. Natl. Acad. Sci. USA 2013, 110:4351-4356. 10.1073/pnas.1217537110.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 4351-4356
-
-
Julien, J.-P.1
Lee, J.H.2
Cupo, A.3
Murin, C.D.4
Derking, R.5
Hoffenberg, S.6
Caulfield, M.J.7
King, C.R.8
Marozsan, A.J.9
Klasse, P.J.10
Sanders, R.W.11
Moore, J.P.12
Wilson, I.A.13
Ward, A.B.14
-
14
-
-
84942811379
-
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike
-
Lee J.H., Leaman D.P., Kim A.S., de la Peña A.T., Sliepen K., Yasmeen A., Derking R., Ramos A., de Taeye S.W., Ozorowski G., Klein F., Burton D.R., Nussenzweig M.C., Poignard P.C., Moore J.P., Klasse P.J., Sanders R.W., Zwick M.B., Wilson I.A., Ward A.B. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat. Commun. 2015, 6:8167. 10.1038/ncomms9167.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8167
-
-
Lee, J.H.1
Leaman, D.P.2
Kim, A.S.3
de la Peña, A.T.4
Sliepen, K.5
Yasmeen, A.6
Derking, R.7
Ramos, A.8
de Taeye, S.W.9
Ozorowski, G.10
Klein, F.11
Burton, D.R.12
Nussenzweig, M.C.13
Poignard, P.C.14
Moore, J.P.15
Klasse, P.J.16
Sanders, R.W.17
Zwick, M.B.18
Wilson, I.A.19
Ward, A.B.20
more..
-
15
-
-
84876797103
-
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
-
Liao H.-X., Lynch R., Zhou T., Gao F., Alam S.M., Boyd S.D., Fire A.Z., Roskin K.M., Schramm C.A., Zhang Z., Zhu J., Shapiro L., Mullikin J.C., Gnanakaran S., Hraber P., Wiehe K., Kelsoe G., Yang G., Xia S.-M., Montefiori D.C., Parks R., Lloyd K.E., Scearce R.M., Soderberg K.A., Cohen M., Kamanga G., Louder M.K., Tran L.M., Chen Y., Cai F., Chen S., Moquin S., Du X., Joyce M.G., Srivatsan S., Zhang B., Zheng A., Shaw G.M., Hahn B.H., Kepler T.B., Korber B.T.M., Kwong P.D., Mascola J.R., Haynes B.F., Becker J., Benjamin B., Blakesley R., Bouffard G., Brooks S., Coleman H., Dekhtyar M., Gregory M., Guan X., Gupta J., Han J., Hargrove A., Ho S., Johnson T., Legaspi R., Lovett S., Maduro Q., Masiello C., Maskeri B., McDowell J., Montemayor C., Mullikin J., Park M., Riebow N., Schandler K., Schmidt B., Sison C., Stantripop M., Thomas J., Thomas P., Vemulapalli M., Young A. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature 2013, 496:469-476. 10.1038/nature12053.
-
(2013)
Nature
, vol.496
, pp. 469-476
-
-
Liao, H.-X.1
Lynch, R.2
Zhou, T.3
Gao, F.4
Alam, S.M.5
Boyd, S.D.6
Fire, A.Z.7
Roskin, K.M.8
Schramm, C.A.9
Zhang, Z.10
Zhu, J.11
Shapiro, L.12
Mullikin, J.C.13
Gnanakaran, S.14
Hraber, P.15
Wiehe, K.16
Kelsoe, G.17
Yang, G.18
Xia, S.-M.19
Montefiori, D.C.20
Parks, R.21
Lloyd, K.E.22
Scearce, R.M.23
Soderberg, K.A.24
Cohen, M.25
Kamanga, G.26
Louder, M.K.27
Tran, L.M.28
Chen, Y.29
Cai, F.30
Chen, S.31
Moquin, S.32
Du, X.33
Joyce, M.G.34
Srivatsan, S.35
Zhang, B.36
Zheng, A.37
Shaw, G.M.38
Hahn, B.H.39
Kepler, T.B.40
Korber, B.T.M.41
Kwong, P.D.42
Mascola, J.R.43
Haynes, B.F.44
Becker, J.45
Benjamin, B.46
Blakesley, R.47
Bouffard, G.48
Brooks, S.49
Coleman, H.50
Dekhtyar, M.51
Gregory, M.52
Guan, X.53
Gupta, J.54
Han, J.55
Hargrove, A.56
Ho, S.57
Johnson, T.58
Legaspi, R.59
Lovett, S.60
Maduro, Q.61
Masiello, C.62
Maskeri, B.63
McDowell, J.64
Montemayor, C.65
Mullikin, J.66
Park, M.67
Riebow, N.68
Schandler, K.69
Schmidt, B.70
Sison, C.71
Stantripop, M.72
Thomas, J.73
Thomas, P.74
Vemulapalli, M.75
Young, A.76
more..
-
16
-
-
84925431182
-
HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies
-
Lynch R.M., Wong P., Tran L., O'Dell S., Nason M.C., Li Y., Wu X., Mascola J.R. HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies. J. Virol. 2015, 89:4201-4213. 10.1128/JVI.03608-14.
-
(2015)
J. Virol.
, vol.89
, pp. 4201-4213
-
-
Lynch, R.M.1
Wong, P.2
Tran, L.3
O'Dell, S.4
Nason, M.C.5
Li, Y.6
Wu, X.7
Mascola, J.R.8
-
17
-
-
84917691102
-
Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies
-
McGuire A.T., Dreyer A.M., Carbonetti S., Lippy A., Glenn J., Scheid J.F., Mouquet H., Stamatatos L. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies. Science 2014, 346:1380-1383. 10.1126/science.1259206.
-
(2014)
Science
, vol.346
, pp. 1380-1383
-
-
McGuire, A.T.1
Dreyer, A.M.2
Carbonetti, S.3
Lippy, A.4
Glenn, J.5
Scheid, J.F.6
Mouquet, H.7
Stamatatos, L.8
-
18
-
-
84896690177
-
Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D
-
McGuire A.T., Glenn J.A., Lippy A., Stamatatos L., Doms R.W. Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D. J. Virol. 2013, 88:2645-2657. 10.1128/JVI.03228-13.
-
(2013)
J. Virol.
, vol.88
, pp. 2645-2657
-
-
McGuire, A.T.1
Glenn, J.A.2
Lippy, A.3
Stamatatos, L.4
Doms, R.W.5
-
19
-
-
84878626061
-
Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
-
McGuire A.T., Hoot S., Dreyer A.M., Lippy A., Stuart A., Cohen K.W., Jardine J., Menis S., Scheid J.F., West A.P., Schief W.R., Stamatatos L. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies. J. Exp. Med. 2013, 210:655-663. 10.1084/jem.20122824.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 655-663
-
-
McGuire, A.T.1
Hoot, S.2
Dreyer, A.M.3
Lippy, A.4
Stuart, A.5
Cohen, K.W.6
Jardine, J.7
Menis, S.8
Scheid, J.F.9
West, A.P.10
Schief, W.R.11
Stamatatos, L.12
-
20
-
-
77954982131
-
Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1
-
Pancera M., McLellan J.S., Wu X., Zhu J., Changela A., Schmidt S.D., Yang Y., Zhou T., Phogat S., Mascola J.R., Kwong P.D. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J. Virol. 2010, 84:8098-8110. 10.1128/JVI.00966-10.
-
(2010)
J. Virol.
, vol.84
, pp. 8098-8110
-
-
Pancera, M.1
McLellan, J.S.2
Wu, X.3
Zhu, J.4
Changela, A.5
Schmidt, S.D.6
Yang, Y.7
Zhou, T.8
Phogat, S.9
Mascola, J.R.10
Kwong, P.D.11
-
21
-
-
84937641486
-
Structural constraints determine the glycosylation of HIV-1 envelope trimers
-
Pritchard L.K., Vasiljevic S., Ozorowski G., Seabright G.E., Cupo A., Ringe R., Kim H.J., Sanders R.W., Doores K.J., Burton D.R., Wilson I.A., Ward A.B., Moore J.P., Crispin M. Structural constraints determine the glycosylation of HIV-1 envelope trimers. Cell Rep. 2015, 11:1604-1613. 10.1016/j.celrep.2015.05.017.
-
(2015)
Cell Rep.
, vol.11
, pp. 1604-1613
-
-
Pritchard, L.K.1
Vasiljevic, S.2
Ozorowski, G.3
Seabright, G.E.4
Cupo, A.5
Ringe, R.6
Kim, H.J.7
Sanders, R.W.8
Doores, K.J.9
Burton, D.R.10
Wilson, I.A.11
Ward, A.B.12
Moore, J.P.13
Crispin, M.14
-
22
-
-
84923172318
-
A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene
-
Pugach P., Ozorowski G., Cupo A., Ringe R., Yasmeen A., de Val N., Derking R., Kim H.J., Korzun J., Golabek M., de Los Reyes K., Ketas T.J., Julien J.-P., Burton D.R., Wilson I.A., Sanders R.W., Klasse P.J., Ward A.B., Moore J.P. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. J. Virol. 2015, 89:3380-3395. 10.1128/JVI.03473-14.
-
(2015)
J. Virol.
, vol.89
, pp. 3380-3395
-
-
Pugach, P.1
Ozorowski, G.2
Cupo, A.3
Ringe, R.4
Yasmeen, A.5
de Val, N.6
Derking, R.7
Kim, H.J.8
Korzun, J.9
Golabek, M.10
de Los Reyes, K.11
Ketas, T.J.12
Julien, J.-P.13
Burton, D.R.14
Wilson, I.A.15
Sanders, R.W.16
Klasse, P.J.17
Ward, A.B.18
Moore, J.P.19
-
23
-
-
84887307095
-
Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation
-
Ringe R.P., Sanders R.W., Yasmeen A., Kim H.J., Lee J.H., Cupo A., Korzun J., Derking R., van Montfort T., Julien J.-P., Wilson I.a., Klasse P.J., Ward A.B., Moore J.P. Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation. Proc. Natl. Acad. Sci. USA 2013, 110:18256-18261. 10.1073/pnas.1314351110.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 18256-18261
-
-
Ringe, R.P.1
Sanders, R.W.2
Yasmeen, A.3
Kim, H.J.4
Lee, J.H.5
Cupo, A.6
Korzun, J.7
Derking, R.8
van Montfort, T.9
Julien, J.-P.10
Wilson, I.11
Klasse, P.J.12
Ward, A.B.13
Moore, J.P.14
-
24
-
-
84884678235
-
A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies
-
Sanders R.W., Derking R., Cupo A., Julien J.P., Yasmeen A., de Val N., Kim H.J., Blattner C., de la Peña A.T., Korzun J., Golabek M., de los Reyes K., Ketas T.J., van Gils M.J., King C.R., Wilson I.A., Ward A.B., Klasse P.J., Moore J.P. A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies. PLoS Pathog. 2013, 9:e1003618. 10.1371/journal.ppat.1003618.
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003618
-
-
Sanders, R.W.1
Derking, R.2
Cupo, A.3
Julien, J.P.4
Yasmeen, A.5
de Val, N.6
Kim, H.J.7
Blattner, C.8
de la Peña, A.T.9
Korzun, J.10
Golabek, M.11
de los Reyes, K.12
Ketas, T.J.13
van Gils, M.J.14
King, C.R.15
Wilson, I.A.16
Ward, A.B.17
Klasse, P.J.18
Moore, J.P.19
-
25
-
-
84937469192
-
HIV-1 neutralizing antibodies induced by native-like envelope trimers
-
Sanders R.W., van Gils M.J., Derking R., Sok D., Ketas T.J., Burger J.A., Ozorowski G., Cupo A., Simonich C., Goo L., Arendt H., Kim H.J., Lee J.H., Pugach P., Williams M., Debnath G., Moldt B., van Breemen M.J., Isik G., Medina-Ramirez M., Back J.W., Koff W.C., Julien J.-P., Rakasz E.G., Seaman M.S., Guttman M., Lee K.K., Klasse P.J., LaBranche C., Schief W.R., Wilson I.A., Overbaugh J., Burton D.R., Ward A.B., Montefiori D.C., Dean H., Moore J.P. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science 2015, 349:aac4223. 10.1126/science.aac4223.
-
(2015)
Science
, vol.349
, pp. aac4223
-
-
Sanders, R.W.1
van Gils, M.J.2
Derking, R.3
Sok, D.4
Ketas, T.J.5
Burger, J.A.6
Ozorowski, G.7
Cupo, A.8
Simonich, C.9
Goo, L.10
Arendt, H.11
Kim, H.J.12
Lee, J.H.13
Pugach, P.14
Williams, M.15
Debnath, G.16
Moldt, B.17
van Breemen, M.J.18
Isik, G.19
Medina-Ramirez, M.20
Back, J.W.21
Koff, W.C.22
Julien, J.-P.23
Rakasz, E.G.24
Seaman, M.S.25
Guttman, M.26
Lee, K.K.27
Klasse, P.J.28
LaBranche, C.29
Schief, W.R.30
Wilson, I.A.31
Overbaugh, J.32
Burton, D.R.33
Ward, A.B.34
Montefiori, D.C.35
Dean, H.36
Moore, J.P.37
more..
-
26
-
-
80052925616
-
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
-
Scheid J.F., Mouquet H., Ueberheide B., Diskin R., Klein F., Oliveira T.Y.K., Pietzsch J., Fenyo D., Abadir A., Velinzon K., Hurley A., Myung S., Boulad F., Poignard P., Burton D.R., Pereyra F., Ho D.D., Walker B.D., Seaman M.S., Bjorkman P.J., Chait B.T., Nussenzweig M.C. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science 2011, 333:1633-1637. 10.1126/science.1207227.
-
(2011)
Science
, vol.333
, pp. 1633-1637
-
-
Scheid, J.F.1
Mouquet, H.2
Ueberheide, B.3
Diskin, R.4
Klein, F.5
Oliveira, T.Y.K.6
Pietzsch, J.7
Fenyo, D.8
Abadir, A.9
Velinzon, K.10
Hurley, A.11
Myung, S.12
Boulad, F.13
Poignard, P.14
Burton, D.R.15
Pereyra, F.16
Ho, D.D.17
Walker, B.D.18
Seaman, M.S.19
Bjorkman, P.J.20
Chait, B.T.21
Nussenzweig, M.C.22
more..
-
27
-
-
84894355475
-
Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign
-
Tran K., Poulsen C., Guenaga J., de Val Alda N., Wilson R., Sundling C., Li Y., Stanfield R.L., Wilson I.a., Ward A.B., Karlsson Hedestam G.B., Wyatt R.T. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc. Natl. Acad. Sci. USA 2014, 111:E738-E747. 10.1073/pnas.1319512111.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. E738-E747
-
-
Tran, K.1
Poulsen, C.2
Guenaga, J.3
de Val Alda, N.4
Wilson, R.5
Sundling, C.6
Li, Y.7
Stanfield, R.L.8
Wilson, I.9
Ward, A.B.10
Karlsson Hedestam, G.B.11
Wyatt, R.T.12
-
28
-
-
84927566324
-
Early development of broadly reactive HIV-1 neutralizing activity in elite neutralizers
-
van den Kerkhof T.L.G.M., Euler Z., van Gils M.J., Boeser-Nunnink B.D., Schuitemaker H., Sanders R.W. Early development of broadly reactive HIV-1 neutralizing activity in elite neutralizers. AIDS 2014, 28:1237-1240. 10.1097/QAD.0000000000000228.
-
(2014)
AIDS
, vol.28
, pp. 1237-1240
-
-
van den Kerkhof, T.L.G.M.1
Euler, Z.2
van Gils, M.J.3
Boeser-Nunnink, B.D.4
Schuitemaker, H.5
Sanders, R.W.6
-
29
-
-
84908477298
-
In vivo protection by broadly neutralizing HIV antibodies
-
van Gils M.J., Sanders R.W. In vivo protection by broadly neutralizing HIV antibodies. Trends Microbiol. 2014, 22:550-551. 10.1016/j.tim.2014.08.006.
-
(2014)
Trends Microbiol.
, vol.22
, pp. 550-551
-
-
van Gils, M.J.1
Sanders, R.W.2
-
30
-
-
84894173514
-
Structural insights on the role of antibodies in HIV-1 vaccine and therapy
-
West A.P., Scharf L., Scheid J.F., Klein F., Bjorkman P.J., Nussenzweig M.C. Structural insights on the role of antibodies in HIV-1 vaccine and therapy. Cell 2014, 156:633-648. 10.1016/j.cell.2014.01.052.
-
(2014)
Cell
, vol.156
, pp. 633-648
-
-
West, A.P.1
Scharf, L.2
Scheid, J.F.3
Klein, F.4
Bjorkman, P.J.5
Nussenzweig, M.C.6
-
31
-
-
80052942203
-
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
-
Wu X., Zhou T., Zhu J., Zhang B., Georgiev I., Wang C., Chen X., Longo N.S., Louder M., McKee K., O'Dell S., Perfetto S., Schmidt S.D., Shi W., Wu L., Yang Y., Yang Z.-Y.Z., Yang Z.-Y.Z., Zhang Z., Bonsignori M., Crump J.a., Kapiga S.H., Sam N.E., Haynes B.F., Simek M., Burton D.R., Koff W.C., Doria-Rose N.a., Connors M., Mullikin J.C., Nabel G.J., Roederer M., Shapiro L., Kwong P.D., Mascola J.R. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science 2011, 333:1593-1602. 10.1126/science.1207532.
-
(2011)
Science
, vol.333
, pp. 1593-1602
-
-
Wu, X.1
Zhou, T.2
Zhu, J.3
Zhang, B.4
Georgiev, I.5
Wang, C.6
Chen, X.7
Longo, N.S.8
Louder, M.9
McKee, K.10
O'Dell, S.11
Perfetto, S.12
Schmidt, S.D.13
Shi, W.14
Wu, L.15
Yang, Y.16
Yang, Z.-Y.Z.17
Yang, Z.-Y.Z.18
Zhang, Z.19
Bonsignori, M.20
Crump, J.21
Kapiga, S.H.22
Sam, N.E.23
Haynes, B.F.24
Simek, M.25
Burton, D.R.26
Koff, W.C.27
Doria-Rose, N.28
Connors, M.29
Mullikin, J.C.30
Nabel, G.J.31
Roederer, M.32
Shapiro, L.33
Kwong, P.D.34
Mascola, J.R.35
more..
-
32
-
-
84903173697
-
Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
-
Yasmeen A., Ringe R., Derking R., Cupo A., Julien J.-P., Burton D.R., Ward A.B., Wilson I.A., Sanders R.W., Moore J.P., Klasse P.J. Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits. Retrovirology 2014, 11:41. 10.1186/1742-4690-11-41.
-
(2014)
Retrovirology
, vol.11
, pp. 41
-
-
Yasmeen, A.1
Ringe, R.2
Derking, R.3
Cupo, A.4
Julien, J.-P.5
Burton, D.R.6
Ward, A.B.7
Wilson, I.A.8
Sanders, R.W.9
Moore, J.P.10
Klasse, P.J.11
|