DRUG POTENCY;
DRUG TARGETING;
DRUG TREATMENT FAILURE;
HUMAN;
HUMAN IMMUNODEFICIENCY VIRUS;
HUMAN IMMUNODEFICIENCY VIRUS INFECTION;
IC50;
IN VIVO STUDY;
INFECTION PREVENTION;
NONHUMAN;
PASSIVE IMMUNIZATION;
RHESUS MONKEY;
SHORT SURVEY;
SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME;
VIRUS ENVELOPE;
VIRUS NEUTRALIZATION;
VIRUS STRAIN;
ANIMAL;
HIV INFECTIONS;
HUMAN IMMUNODEFICIENCY VIRUS 1;
IMMUNOLOGY;
AIDS VACCINES;
ANIMALS;
ANTIBODIES, NEUTRALIZING;
HIV ANTIBODIES;
HIV INFECTIONS;
HIV-1;
HUMANS;
IMMUNIZATION, PASSIVE;
MACACA MULATTA;
Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor
Pegu A., et al. Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Sci. Transl. Med. 2014, 6:243ra288.
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
Parren P.W.H.I., et al. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J. Virol. 2001, 75:8240-8347.
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
Hessell A.J., et al. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog. 2009, 5:e1000433.
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
Mascola J.R., et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat. Med. 2000, 6:207-210.
Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
Moldt B., et al. Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:18921-18925.