HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies

Journal of Virology

Volumn 89, Issue 8, 2015, Pages 4201-4213

  Lynch, Rebecca M ^a   Wong, Patrick ^a   Tran, Lillian ^a   O'Dell, Sijy ^a   Nason, Martha C ^a   Li, Yuxing ^b   Wu, Xueling ^c   Mascola, John R ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c AARON DIAMOND AIDS RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 120; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; VRC01 ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; MONOCLONAL ANTIBODY; VRC01 MONOCLONAL ANTIBODY;

AMINO TERMINAL SEQUENCE; ANTIBODY COMBINING SITE; ANTIGEN RECOGNITION; AREA UNDER THE CURVE; ARTICLE; CARBOXY TERMINAL SEQUENCE; GENE AMPLIFICATION; GENE MAPPING; GLYCOSYLATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; REVERTANT; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS INFECTIVITY; VIRUS REPLICATION; VIRUS RESISTANCE; VIRUS SPIKE; VIRUS STRAIN; AMINO ACID SEQUENCE; DNA SEQUENCE; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE EVASION; IMMUNOLOGY; REPRODUCTIVE FITNESS; SEQUENCE ALIGNMENT; SERODIAGNOSIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIGENS, CD4; GENETIC FITNESS; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HUMANS; IMMUNE EVASION; MUTAGENESIS, SITE-DIRECTED; NEUTRALIZATION TESTS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; VIRAL ENVELOPE PROTEINS;

EID: 84925431182     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03608-14     Document Type: Article

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