Identification of an HIV-1 clade a envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes

Journal of Virology

Volumn 87, Issue 10, 2013, Pages 5372-5383

  Hoffenberg, Simon ^a   Powell, Rebecca ^a   Carpov, Alexei ^a   Wagner, Denise ^a   Wilson, Aaron ^a   Pond, Sergei Kosakovsky ^b   Lindsay, Ross ^a   Arendt, Heather ^a   DeStefano, Joanne ^a   Phogat, Sanjay ^a,h   Poignard, Pascal ^c   Fling, Steven P ^c   Simek, Melissa ^a   LaBranche, Celia ^d   Montefiori, David ^d   Wrin, Terri ^e   Phung, Pham ^e   Burton, Dennis ^c,f,g   Koff, Wayne ^a   King, C Richter ^a   Parks, Christopher L ^a   Caulfield, Michael J ^a   more..

^a INTERNATIONAL AIDS VACCINE INITIATIVE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ILTAB   (United States)

^d DUKE UNIVERSITY   (United States)

^e MONOGRAM BIOSCIENCES   (United States)

^f SCRIPPS RESEARCH INSTITUTE   (United States)

^g MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^h SANOFI PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; MONOMER; NEUTRALIZING ANTIBODY; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ANTIBODY TITER; ANTIGENICITY; ARTICLE; BIOINFORMATICS; CLADISTICS; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMALE; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOGENICITY; MOST RECENT COMMON ANCESTOR; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANISMS BY PHYLOGENETIC POSITION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN TARGETING; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; VIRUS ENVELOPE; VIRUS IDENTIFICATION; VIRUS NEUTRALIZATION;

ANTIBODIES, NEUTRALIZING; COMPUTATIONAL BIOLOGY; EPITOPES; FEMALE; GENOTYPE; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS;

EID: 84877350114     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02827-12     Document Type: Article

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