Chemically modified RNA activated matrices enhance bone regeneration

Journal of Controlled Release

Volumn 218, Issue , 2015, Pages 22-28

  Elangovan, Satheesh ^a   Khorsand, Behnoush ^b   Do, Anh Vu ^b   Hong, Liu ^a   Dewerth, Alexander ^c   Kormann, Michael ^c   Ross, Ryan D ^d   Rick Sumner, D ^d   Allamargot, Chantal ^b   Salem, Aliasger K ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d RUSH MEDICAL COLLEGE   (United States)

Author keywords

Bone morphogenetic protein 2; Bone regeneration; Chemically modified RNA; Gene delivery; Plasmid DNA; Polyethylenimine

Indexed keywords

BIOMOLECULES; DNA; EFFICIENCY; ENCODING (SYMBOLS); GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENES; MOLECULAR BIOLOGY; NUCLEIC ACIDS; PHOSPHATASES; PROTEINS; RNA; SCAFFOLDS (BIOLOGY);

BONE MORPHOGENETIC PROTEIN-2; BONE REGENERATION; CHEMICALLY MODIFIED; GENE DELIVERY; PLASMID DNA; POLYETHYLENIMINES;

BONE;

ALKALINE PHOSPHATASE; AMINE; BONE MORPHOGENETIC PROTEIN 2; CHEMICALLY MODI RIBONUCLEIC ACID; COLLAGEN; OSTEOCALCIN; PHOSPHATE; PLASMID DNA; POLYETHYLENEIMINE; RNA; UNCLASSIFIED DRUG; VIRUS VECTOR; DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; BONE DEFECT; BONE MARROW STROMA CELL; BONE REGENERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG SAFETY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT; ANIMAL; BAGG ALBINO MOUSE; BONE MARROW CELL; CELL SURVIVAL; CHEMISTRY; CRANIOCEREBRAL TRAUMA; CYTOLOGY; FISCHER 344 RAT; GENE THERAPY; GENETICS; MALE; METABOLISM; PLASMID; STROMA CELL;

ALKALINE PHOSPHATASE; ANIMALS; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CELL SURVIVAL; CRANIOCEREBRAL TRAUMA; DNA; GENETIC THERAPY; HUMANS; MALE; MICE, INBRED BALB C; OSTEOCALCIN; PLASMIDS; POLYETHYLENEIMINE; RATS, INBRED F344; RNA; STROMAL CELLS;

EID: 84943261199     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.09.050     Document Type: Article

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