메뉴 건너뛰기




Volumn 134, Issue 3, 2003, Pages 378-384

Cancer immunotherapy using RNA-loaded dendritic cells

Author keywords

Dendritic cells; Electroporation; Immunotherapy, RNA; T cells

Indexed keywords

CANCER VACCINE; CD4 ANTIGEN; CD8 ANTIGEN; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RNA;

EID: 0346751949     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2003.02286.x     Document Type: Review
Times cited : (100)

References (41)
  • 2
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392:245-52.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 3
    • 0036659913 scopus 로고    scopus 로고
    • Antigen-bearing immature dendritic cells induce peptide-specific CD8 (+) regulatory T cells in vivo in humans
    • Dhodapkar MV, Steinman RM. Antigen-bearing immature dendritic cells induce peptide-specific CD8 (+) regulatory T cells in vivo in humans. Blood 2002; 100:174-7.
    • (2002) Blood , vol.100 , pp. 174-177
    • Dhodapkar, M.V.1    Steinman, R.M.2
  • 4
    • 0037099719 scopus 로고    scopus 로고
    • Infectious tolerance: Human CD25 (+) regulatory T cells convey suppressor activity to conventional CD4 (+) T helper cells
    • Jonuleit H, Schmitt E, Kakirman H, Stassen M, Knop J, Enk AH. Infectious tolerance: human CD25 (+) regulatory T cells convey suppressor activity to conventional CD4 (+) T helper cells. J Exp Med 2002; 196:255-60.
    • (2002) J Exp Med , vol.196 , pp. 255-260
    • Jonuleit, H.1    Schmitt, E.2    Kakirman, H.3    Stassen, M.4    Knop, J.5    Enk, A.H.6
  • 6
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • Steinman RM, Nussenzweig MC. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci USA 2002; 99:351-8.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 7
    • 8544247898 scopus 로고    scopus 로고
    • Generation of dendritic cells from bone marrow progenitors using GM-CSF, TNF-α, and additional cytokines: Antagonistic effects of IL-4 and IFN-γ and selective involvement of TNF-α receptor-1
    • Lardon F, Snoeck HW, Berneman ZN et al. Generation of dendritic cells from bone marrow progenitors using GM-CSF, TNF-α, and additional cytokines: antagonistic effects of IL-4 and IFN-γ and selective involvement of TNF-α receptor-1. Immunology 1997; 91:553-9.
    • (1997) Immunology , vol.91 , pp. 553-559
    • Lardon, F.1    Snoeck, H.W.2    Berneman, Z.N.3
  • 8
    • 10144230702 scopus 로고    scopus 로고
    • + hematopoietic progenitor cells toward distinct dendritic cell subsets of the Birbeck granule and MIIC-positive Langerhans cell and the interdigitating dendritic cell type
    • + hematopoietic progenitor cells toward distinct dendritic cell subsets of the Birbeck granule and MIIC-positive Langerhans cell and the interdigitating dendritic cell type. Blood 1996; 88:2541-8.
    • (1996) Blood , vol.88 , pp. 2541-2548
    • Herbst, B.1    Köhler, G.2    Mackensen, A.3
  • 9
    • 0028285230 scopus 로고
    • Proliferating dendritic cell progenitors in human blood
    • Romani N, Gruner S, Brang D et al. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994; 180:83-93.
    • (1994) J Exp Med , vol.180 , pp. 83-93
    • Romani, N.1    Gruner, S.2    Brang, D.3
  • 10
    • 0035990375 scopus 로고    scopus 로고
    • Current methods for loading dendritic cells with tumor antigen for induction of antitumor immunity
    • Zhou Y, Bosch ML, Salgaller ML. Current methods for loading dendritic cells with tumor antigen for induction of antitumor immunity. J Immunother 2002; 25:289-303.
    • (2002) J Immunother , vol.25 , pp. 289-303
    • Zhou, Y.1    Bosch, M.L.2    Salgaller, M.L.3
  • 11
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with Mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
    • Thurner B, Haendle I, Röder C et al. Vaccination with Mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J Exp Med 1999; 11:1669-78.
    • (1999) J Exp Med , vol.11 , pp. 1669-1678
    • Thurner, B.1    Haendle, I.2    Röder, C.3
  • 12
    • 0033056681 scopus 로고    scopus 로고
    • Induction of human papillomavirus-specific CD4 (+) and CD8 (+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16-and 18-positive cervical cancer
    • Santin AD, Hermonat PL, Ravaggi A et al. Induction of human papillomavirus-specific CD4 (+) and CD8 (+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16-and 18-positive cervical cancer. J Virol 1999; 3:5402-10.
    • (1999) J Virol , vol.3 , pp. 5402-5410
    • Santin, A.D.1    Hermonat, P.L.2    Ravaggi, A.3
  • 13
    • 0034283723 scopus 로고    scopus 로고
    • Mature dendritic cells pulsed with freeze-thaw cell lysates define an effective in vitro vaccine designed to elicit EBV-specific CD4 (+) and CD8 (+) T lymphocyte responses
    • Herr W, Ranieri E, Olson W, Zarour H, Gesualdo L, Storkus WJ. Mature dendritic cells pulsed with freeze-thaw cell lysates define an effective in vitro vaccine designed to elicit EBV-specific CD4 (+) and CD8 (+) T lymphocyte responses. Blood 2000; 96:1857-64.
    • (2000) Blood , vol.96 , pp. 1857-1864
    • Herr, W.1    Ranieri, E.2    Olson, W.3    Zarour, H.4    Gesualdo, L.5    Storkus, W.J.6
  • 14
    • 0034108143 scopus 로고    scopus 로고
    • Induction of cellular immunity in a parathyroid carcinoma treated with tumor lysate-pulsed dendritic cells
    • Schott M, Feldkamp J, Schattenberg D et al. Induction of cellular immunity in a parathyroid carcinoma treated with tumor lysate-pulsed dendritic cells. Eur J Endocrin 2000; 142:300-6.
    • (2000) Eur J Endocrin , vol.142 , pp. 300-306
    • Schott, M.1    Feldkamp, J.2    Schattenberg, D.3
  • 15
    • 0034100896 scopus 로고    scopus 로고
    • Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids
    • Kugler A, Stuhler G, Walden P et al. Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids. Nat Med 2000; 6:332-6.
    • (2000) Nat Med , vol.6 , pp. 332-336
    • Kugler, A.1    Stuhler, G.2    Walden, P.3
  • 16
    • 0034630499 scopus 로고    scopus 로고
    • Gene-modified dendritic cells for use in tumor vaccines
    • Kirk CJ, Mulé JJ. Gene-modified dendritic cells for use in tumor vaccines. Hum Gene Ther 2000; 11:797-806.
    • (2000) Hum Gene Ther , vol.11 , pp. 797-806
    • Kirk, C.J.1    Mulé, J.J.2
  • 17
    • 0034913277 scopus 로고    scopus 로고
    • Viral vectors for dendritic cell-based immunotherapy
    • Jenne L, Schuler G, Steinkasserer A. Viral vectors for dendritic cell-based immunotherapy. Trends Immunol 2001; 22:102-7.
    • (2001) Trends Immunol , vol.22 , pp. 102-107
    • Jenne, L.1    Schuler, G.2    Steinkasserer, A.3
  • 18
    • 7144250527 scopus 로고    scopus 로고
    • Nonviral transfection of distinct types of human dendritic cells: High-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells
    • Van Tendeloo VFI, Snoeck HW, Lardon F et al. Nonviral transfection of distinct types of human dendritic cells: high-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells. Gene Ther 1998; 5:700-7.
    • (1998) Gene Ther , vol.5 , pp. 700-707
    • Van Tendeloo, V.F.I.1    Snoeck, H.W.2    Lardon, F.3
  • 19
    • 0029839058 scopus 로고    scopus 로고
    • Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo
    • Boczkowski D, Nair SK, Snyder D, Gilboa E. Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. J Exp Med 1996; 184:465-72.
    • (1996) J Exp Med , vol.184 , pp. 465-472
    • Boczkowski, D.1    Nair, S.K.2    Snyder, D.3    Gilboa, E.4
  • 20
    • 0030808677 scopus 로고    scopus 로고
    • Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors
    • Ashley DM, Faiola B, Nair S, Hale LP, Bigner DD, Gilboa E. Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors. J Exp Med 1997; 186:1177-82.
    • (1997) J Exp Med , vol.186 , pp. 1177-1182
    • Ashley, D.M.1    Faiola, B.2    Nair, S.3    Hale, L.P.4    Bigner, D.D.5    Gilboa, E.6
  • 21
    • 0031960397 scopus 로고    scopus 로고
    • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
    • Nair SK, Boczkowski D, Morse M, Cumming RI, Lyerly HK, Gilboa E. Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nat Biotechnol 1998; 16:364-9.
    • (1998) Nat Biotechnol , vol.16 , pp. 364-369
    • Nair, S.K.1    Boczkowski, D.2    Morse, M.3    Cumming, R.I.4    Lyerly, H.K.5    Gilboa, E.6
  • 22
    • 0034517560 scopus 로고    scopus 로고
    • Human dendritic cells transfected with either RNA or DNA encoding influenza matrix protein M1 differ in their ability to stimulate cytotoxic T lymphocytes
    • Strobel I, Berchtold S, Gotze A, Schulze U, Schuler G, Steinkasserer A. Human dendritic cells transfected with either RNA or DNA encoding influenza matrix protein M1 differ in their ability to stimulate cytotoxic T lymphocytes. Gene Ther 2000; 7:2028-35.
    • (2000) Gene Ther , vol.7 , pp. 2028-2035
    • Strobel, I.1    Berchtold, S.2    Gotze, A.3    Schulze, U.4    Schuler, G.5    Steinkasserer, A.6
  • 23
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells. Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • Van Tendeloo V, Ponsaerts P, Lardon F et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells. Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 2001; 98:49-56.
    • (2001) Blood , vol.98 , pp. 49-56
    • Van Tendeloo, V.1    Ponsaerts, P.2    Lardon, F.3
  • 24
    • 0036049777 scopus 로고    scopus 로고
    • mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation
    • Ponsaerts P, Van Tendeloo VFI, Cools N et al. mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation. Leukemia 2002; 16:1324-30.
    • (2002) Leukemia , vol.16 , pp. 1324-1330
    • Ponsaerts, P.1    Van Tendeloo, V.F.I.2    Cools, N.3
  • 25
    • 0036133166 scopus 로고    scopus 로고
    • mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT)
    • Sæbøe-Larssen S, Fossberg E, Gaudernack G. mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT). J Immunol Meth 2002; 259:191-203.
    • (2002) J Immunol Meth , vol.259 , pp. 191-203
    • Sæbøe-Larssen, S.1    Fossberg, E.2    Gaudernack, G.3
  • 27
    • 0036844382 scopus 로고    scopus 로고
    • Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection
    • Lundqvist A, Noffz G, Pavlenko M et al. Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection. J Immunother 2002; 25:445-54.
    • (2002) J Immunother , vol.25 , pp. 445-454
    • Lundqvist, A.1    Noffz, G.2    Pavlenko, M.3
  • 28
    • 0036708241 scopus 로고    scopus 로고
    • Efficient genetic modifications of murine dendritic cells by electroporation with mRNA
    • Van Meirvenne S, Straetman L, Heirman C et al. Efficient genetic modifications of murine dendritic cells by electroporation with mRNA. Cancer Gene Ther 2002; 9:787-97.
    • (2002) Cancer Gene Ther , vol.9 , pp. 787-797
    • Van Meirvenne, S.1    Straetman, L.2    Heirman, C.3
  • 31
    • 0036735405 scopus 로고    scopus 로고
    • + T cells using dendritic cells transfected with RNA encoding a chimeric gene product
    • + T cells using dendritic cells transfected with RNA encoding a chimeric gene product. Cancer Res 2002; 62:5041-8.
    • (2002) Cancer Res , vol.62 , pp. 5041-5048
    • Su, Z.1    Vieweg, J.2    Weizer, A.Z.3
  • 32
    • 0033947945 scopus 로고    scopus 로고
    • Induction of cytotoxic T lymphocytes with dendritic cells transfected with human papillomavirus E6 and E7 RNA: Implications for cervival cancer immunotherapy
    • Thornburg C, Boczkowski D, Gilboa E, Nair SK. Induction of cytotoxic T lymphocytes with dendritic cells transfected with human papillomavirus E6 and E7 RNA: implications for cervival cancer immunotherapy. J Immunother 2000; 23:412-8.
    • (2000) J Immunother , vol.23 , pp. 412-418
    • Thornburg, C.1    Boczkowski, D.2    Gilboa, E.3    Nair, S.K.4
  • 33
    • 0034657782 scopus 로고    scopus 로고
    • Human dendritic cells transfected with RNA encoding prostate-specific antigen stimulate prostate-specific CTL responses in vitro
    • Heiser H, Dahm P, Yancey DR et al. Human dendritic cells transfected with RNA encoding prostate-specific antigen stimulate prostate-specific CTL responses in vitro. J Immunol 2000; 164:5508-14.
    • (2000) J Immunol , vol.164 , pp. 5508-5514
    • Heiser, H.1    Dahm, P.2    Yancey, D.R.3
  • 34
    • 0034667917 scopus 로고    scopus 로고
    • HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in vitro primary immune response
    • Weissman D, Ni HP, Scales D et al. HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in vitro primary immune response. J Immunol 2000; 165:4710-7.
    • (2000) J Immunol , vol.165 , pp. 4710-4717
    • Weissman, D.1    Ni, H.P.2    Scales, D.3
  • 35
    • 0037103350 scopus 로고    scopus 로고
    • Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells
    • Ponsaerts P, Van den Bosch G, Cools N et al. Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells. J Immunol 2002; 169:1669-75.
    • (2002) J Immunol , vol.169 , pp. 1669-1675
    • Ponsaerts, P.1    Van Den Bosch, G.2    Cools, N.3
  • 36
    • 0035870244 scopus 로고    scopus 로고
    • Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T cell responses against antigens expressed by primary and metastatic tumors
    • Heiser A, Maurice MA, Yancey DR, Coleman DM, Dahm P, Vieweg J. Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T cell responses against antigens expressed by primary and metastatic tumors. Cancer Res 2001; 61:3388-93.
    • (2001) Cancer Res , vol.61 , pp. 3388-3393
    • Heiser, A.1    Maurice, M.A.2    Yancey, D.R.3    Coleman, D.M.4    Dahm, P.5    Vieweg, J.6
  • 37
    • 0034652624 scopus 로고    scopus 로고
    • Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells
    • Boczkowski D, Nair SK, Nam JH, Lyerly HK, Gilboa E. Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells. Cancer Res 2000; 60:1028-34.
    • (2000) Cancer Res , vol.60 , pp. 1028-1034
    • Boczkowski, D.1    Nair, S.K.2    Nam, J.H.3    Lyerly, H.K.4    Gilboa, E.5
  • 38
    • 0035284901 scopus 로고    scopus 로고
    • Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA
    • Heiser A, Maurice MA, Yancey DR et al. Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA. J Immunol 2001; 166:2953-60.
    • (2001) J Immunol , vol.166 , pp. 2953-2960
    • Heiser, A.1    Maurice, M.A.2    Yancey, D.R.3
  • 39
    • 0037305571 scopus 로고    scopus 로고
    • Induction of myeloma specific cytotoxic T cells using dendritic cells transfected with tumor-derived RNA
    • Milazzo C, Reichardt VL, Müller MR, Grünebach F, Brossart P. Induction of myeloma specific cytotoxic T cells using dendritic cells transfected with tumor-derived RNA. Blood 2002; 101:977-82.
    • (2002) Blood , vol.101 , pp. 977-982
    • Milazzo, C.1    Reichardt, V.L.2    Müller, M.R.3    Grünebach, F.4    Brossart, P.5
  • 40
    • 0036167308 scopus 로고    scopus 로고
    • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors
    • Heiser A, Coleman DM, Dannull J et al. Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 2001; 109:409-17.
    • (2001) J Clin Invest , vol.109 , pp. 409-417
    • Heiser, A.1    Coleman, D.M.2    Dannull, J.3
  • 41
    • 0036203164 scopus 로고    scopus 로고
    • Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells
    • Nair SK, Morse M, Boczkowski D et al. Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells. Ann Surg 2002; 235:540-9.
    • (2002) Ann Surg , vol.235 , pp. 540-549
    • Nair, S.K.1    Morse, M.2    Boczkowski, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.