Locally controlled delivery of TNFα antibody from a novel glucose-sensitive scaffold enhances alveolar bone healing in diabetic conditions

Journal of Controlled Release

Volumn 206, Issue , 2015, Pages 232-242

  Wang, Qi ^a   Li, Hao ^a   Xiao, Yu ^a   Li, Shuan ^a   Li, Bo ^a   Zhao, Xiaowen ^b   Ye, Lin ^b   Guo, Bin ^c   Chen, Xinmin ^a   Ding, Yi ^a   Bao, Chongyun ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Alveolar bone defect; Diabetes; Glucose sensitive drug delivery; Scaffold; TNF antibody

Indexed keywords

ANTIBODIES; DEFECTS; DRUG DELIVERY; GLUCOSE; MEDICAL PROBLEMS; PATHOLOGY; RATS; REPAIR; SCAFFOLDS;

ALVEOLAR BONES; BLOOD GLUCOSE LEVEL; BONE MARROW STROMAL CELLS; CONTROLLED DELIVERY; GLUCOSE SENSITIVES; INFLAMMATORY RESPONSE; QUATERNIZED CHITOSANS; THERAPEUTIC STRATEGY;

BONE;

CHITOSAN DERIVATIVE; COLLAGEN; CXCL1 CHEMOKINE; DRUG CARRIER; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN GLARGINE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; ANTIBODY; CHITOSAN; DELAYED RELEASE FORMULATION;

ALVEOLAR BONE DEFECT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DEFECT; BONE MARROW STROMA CELL; BONE REGENERATION; BONE REMODELING; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT MODEL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TIMED DRUG RELEASE; ALVEOLAR BONE LOSS; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; CHEMISTRY; COMPLICATION; CYTOLOGY; DELAYED RELEASE FORMULATION; DIABETES COMPLICATIONS; DRUG DELIVERY SYSTEM; IMMUNOLOGY; MESENCHYMAL STROMA CELL; PATHOLOGY; TISSUE SCAFFOLD; WISTAR RAT;

ALVEOLAR BONE LOSS; ANIMALS; ANTIBODIES; BONE REGENERATION; CELLS, CULTURED; CHITOSAN; DELAYED-ACTION PREPARATIONS; DIABETES COMPLICATIONS; DRUG DELIVERY SYSTEMS; MALE; MESENCHYMAL STROMAL CELLS; RATS, WISTAR; TISSUE SCAFFOLDS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84926207179     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.03.019     Document Type: Article

References (41)

1. Q. Wang, H.H. Xie, M. Fu, B. Guo, Y. Ding, W. Li, and H.Y. Yu 25-Hydroxyvitamin D3 attenuates experimental periodontitis through downregulation of TLR4 and JAK1/STAT3 signaling in diabetic mice J. Steroid Biochem. Mol. Biol. 135 2013 43 50
2. F.Z. Xu, Y. Chen, and T.D. Graves Abnormal cell responses and role of TNF-alpha in impaired diabetic wound healing BioMed. Res. Int. 2013 2013 754802
3. P.M. Mountziaris, E.D. Lehman, I. Mountziaris, D.C. Sing, F.K. Kasper, and A.G. Mikos Effect of temporally patterned TNF-alpha delivery on in vitro osteogenic differentiation of mesenchymal stem cells cultured on biodegradable polymer scaffolds J. Biomater. Sci. Polym. Ed. 24 2013 1794 1813
4. J. Pers, A. Saraux, R. Pierre, and P. Youinou Anti-TNF-alpha immunotherapy is associated with increased gingival inflammation without clinical attachment loss in subjects with rheumatoid arthritis J. Periodontol. 799 2008 1645 1651
5. P.C. Chang, M.C. Chung, Y.P. Wang, L.Y. Chien, J.C. Lim, K. Liang, L.Y. Chong, Y.P. Kuo, C.H. Chen, and H.C. Chiang Patterns of diabetic periodontal wound repair: a study using micro-computed tomography and immunohistochemistry J. Periodontol. 83 2012 644 652
6. P. Losi, E. Briqanti, C. Errico, A. Lisella, E. Sanquinetti, F. Chiellini, and G. Soldani Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice Acta Biomater. 9 2013 7814 7821
7. N. Teich Topical application of TNF-blockers [review] Dtsch. Med. Wochenschr. 138 2013 381 385
8. F. Cornillie, D. Shealy, G. D'Haens, K. Geboes, G.V. Assche, J. Ceuppens, C. Wagner, T. Schaible, S.E. Plevy, S.R. Targan, and P. Rutgeerts Infliximab induces potent anti-inflammatory and local immunomodulatory activity but no systemic immune suppression in patients with Crohn's disease Aliment. Pharmacol. Ther. 15 2001 463 473
9. M.J. Taylor, S. Tanna, and T. Sahota In vivo study of a polymeric glucose-sensitive insulin delivery system using a rat model J. Pharm. Sci. 99 2010 4215 4227
10. N. Bhattarai, J. Gunn, and M. Zhang Chitosan-based hydrogels for controlled, localized drug delivery Adv. Drug Deliv. Rev. 62 2010 83 99
11. R. Croutze, N. Jomha, H. Uludag, and A. Adesida Matrix forming characteristics of inner and outer human meniscus cells on 3D collagen scaffolds under normal and low oxygen tensions BMC Musculoskelet. Disord. 14 2013 353
12. Q.X. Ji, D.Y. Zhong, R. Lü, W.Q. Zhang, J. Deng, and X.G. Chen In vitro evaluation of the biomedical properties of chitosan and quaternized chitosan for dental applications Carbohydr. Res. 344 2009 1297 1302
13. Y. Chen, C. Tang, J. Zhang, M. Gong, B. Su, and F. Qiu Self-assembling surfactant-like peptide A6K as potential delivery system for hydrophobic drugs Int. J. Nanomedicine 10 2015 847 858
14. K. Kim, D. Dean, J. Wallace, R. Breithaupt, A.G. Mikos, and J.P. Fisher The influence of stereolithographic scaffold architecture and composition on osteogenic signal expression with rat bone marrow stromal cells Biomaterials 32 2011 3750 3763
15. H. Li, H. Yang, Y. Ding, R. Aprecio, W. Zhang, Q. Wang, and Y.M. Li Experimental periodontitis induced by Porphyromonas gingivalis does not alter the onset or severity of diabetes in mice J. Periodontal Res. 48 2013 582 590
16. J.M. Lane, and H.S. Sandhu Current approaches to experimental bone grafting Orthop. Clin. N. Am. 18 1987 213 225
17. M. Prabaharan, M.A. Rodriguez-Perez, J.A. de Saja, and J.F. Mano Preparation and characterization of poly(l-lactic acid)-chitosan hybrid scaffolds with drug release capability J. Biomed. Mater. Res. B Appl. Biomater. 81B 2007 427 434
18. Guobao Wei, Qiming Jin, William V. Giannobile, and Peter X. Maa Nano-fibrous scaffold for controlled delivery of recombinant human PDGF-BB J. Control. Release 112 2006 103 110
19. L.Y. Chen, Z.G. Tian, and Y.M. Du Synthesis and pH sensitivity of carboxymethyl chitosan-based polyamppholyte hydrogels for protein carrier matrices Biomaterials 25 2004 3725 3732
20. H. Shi, J. Ma, N. Zhao, Y. Chen, and Y. Liao Periodontal regeneration in experimentally-induced alveolar bone dehiscence by an improved porous biphasic calcium phosphate ceramic in beagle dogs J. Mater. Sci. Mater. Med. 19 2008 3515 3524
21. M. Prabaharan Review paper: chitosan derivatives as promising materials for controlled drug delivery J. Biomater. Appl. 23 2008 5 36
22. J. Wu, Z.G. Su, and G.H. Ma A thermo- and pH-sensitive hydrogel composed of quaternized chitosan/glycerophosphate Int. J. Pharm. 315 2006 1 11
23. T. Traitel, Y. Cohen, and J. Kost Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions Biomaterials 21 2000 1679 1687
24. C.M. Ohlrich, and J. Leichter Diabetes, periodontitis, and the subgingival microbiota J. Oral Microbiol. 2 2010 10 34
25. S.H. Kim, K.H. Kim, B.M. Seo, K.T. Koo, T.I. Kim, Y.J. Seol, Y. Ku, I.C. Rhyu, C.P. Chung, and Y.M. Lee Alveolar bone regeneration by transplantation of periodontal ligament stem cells and bone marrow stem cells in a canine peri-implant defect model: a pilot study J. Periodontol. 80 2009 1815 1823
26. X. Chen, Y. Zhao, S. Geng, R.J. Miron, Q. Zhang, C. Wu, and Y. Zhang In vivo experimental study on bone regeneration in critical bone defects using PIB nanogels/boron-containing mesoporous bioactive glass composite scaffold Int. J. Nanomedicine 10 2015 839 846
27. M.A. Baxter The role of new basal insulin analogues in the initiation and optimisation of insulin therapy in type 2 diabetes Acta Diabetol. 45 2008 253 268
28. N.D. Pham, I. Barthélémy, T. Orliaguet, A. Artola, J.M. Mondié, and R. Dallel Etiology, distribution, treatment modalities and complications of maxillofacial fractures Med. Oral Patol. Oral Cir. Bucal 19 2013 e261 e269
29. J.R. Funk, J.E. Hale, D. Carmines, H.L. Gooch, and S.R. Hurwitz Biomechanical evaluation of early fracture healing in normal and diabetic rats J. Orthop. Res. 18 2000 126 132
30. F. Nishimura, Y. Iwamoto, J. Mineshiba, A. Shimizu, Y. Soga, and Y. Murayama Periodontal disease and diabetes mellitus: the role of tumor necrosis factor-alpha in a 2-way relationship J. Periodontol. 74 2003 97 102
31. M. Li, L. Yu, T. She, Y. Gan, F. Liu, Z. Hu, Y. Chen, S. Li, and H. Xia Astragaloside IV attenuates Toll-like receptor 4 expression via NF-kB pathway under high glucose condition in mesenchymal stem cells Eur. J. Pharmacol. 696 2012 203 209
32. A. Yadav, V. Saini, and S. Arora MCP-1: chemoattractant with a role beyond immunity: a review Clin. Chim. Acta 411 2010 1570 1579
33. T. Omatsu, G. Cepinskas, C. Clarson, E.K. Patterson, I.M. Alharfi, K. Summers, P.O. Couraud, I.A. Romero, B. Weksler, and D.D. Fraser Canadian Critical Care Translational Biology Group, CXCL1/CXCL8 (GROalpha/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro Am. J. Physiol. Endocrinol. Metab. 306 2014 E1077 E1084
34. W. Huang, S.Y. Yang, J. Shao, and Y.P. Li Signaling and transcriptional regulation in osteoblast commitment and differentiation Front. Biosci. 12 2007 3068 3092
35. K. Nakashima, X. Zhou, G. Kunkel, Z. Zhang, J.M. Deng, R.R. Behringer, and B.D. Crombrugghe The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation Cell 108 2002 17 29
36. A. Neve, A. Corrado, and F.P. Cantatore Osteocalcin: skeletal and extra-skeletal effects J. Cell. Physiol. 228 2013 1149 1153
37. Y. Jeong, W. Yang, H. Ko, and M. Kim The effects of bone morphogenetic protein-2 and enamel matrix derivative on the bioactivity of mineral trioxide aggregate in MC3T3-E1cells Restor. Dent. Endod. 39 2014 187 194
38. B.R. Genge, G.R. Sauer, L.N. Wu, F.M. McLean, and R.E. Wuthier Correlation between loss of alkaline phosphatase activity and accumulation of calcium during matrix vesicle-mediated mineralization J. Biol. Chem. 263 1988 18513 18519
39. C.M. Kaneto, P.S. Lima, D.L. Zanette, K.L. Prata, J.M. Pina Neto, F.J. de Paula, and W.J. Silva COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from osteogenesis imperfecta patients BMC Med. Genet. 15 2014 45
40. M. Thayu, M.B. Leonard, J.S. Hyams, W.V. Crandall, S. Kugathasan, A.R. Otley, A. Olson, J. Johanns, C.W. Marano, R.B. Heuschkel, G. Veereman-Wauters, A.M. Griffiths, R.N. Baldassano, and Reach Study Group Improvement in biomarkers of bone formation during infliximab therapy in pediatric Crohn's disease: results of the REACH study Clin. Gastroenterol. Hepatol. 6 2008 1378 1384
41. A. Szentpetery, M.J. McKenna, B.F. Merray, C.T. Ng, J.J. Brady, M. Morrin, B. Radovits, D.J. Veale, and O. Fitzgerald Periarticular bone gain at proximal interphalangeal joints and changes in bone turnover markers in response to tumor necrosis factor inhibitors in rheumatoid and psoriatic arthritis J. Rheumatol. 40 2013 653 662