Development of collagen-hydroxyapatite scaffolds incorporating PLGA and alginate microparticles for the controlled delivery of rhBMP-2 for bone tissue engineering

Journal of Controlled Release

Volumn 198, Issue , 2015, Pages 71-79

  Quinlan, Elaine ^a,b   López Noriega, Adolfo ^a,b   Thompson, Emmet ^a,b   Kelly, Helena M ^a   Cryan, Sally Ann ^a,b   O'Brien, Fergal J ^a,b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Bone tissue engineering; Calcium alginate; Collagen based scaffolds; Microparticles; PLGA; rhBMP 2

Indexed keywords

ALGINATE; BONE; COLLAGEN; EMULSIFICATION; ENCAPSULATION; HYDROXYAPATITE; SCAFFOLDS (BIOLOGY); TISSUE; TISSUE ENGINEERING;

BONE TISSUE ENGINEERING; CALCIUM ALGINATE; COLLAGEN-BASED SCAFFOLDS; MICRO-PARTICLES; PLGA; RHBMP-2;

TISSUE REGENERATION;

ALGINIC ACID; COLLAGEN; HYDROXYAPATITE; MOLECULAR SCAFFOLD; POLYGLACTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 2; DRUG CARRIER; GLUCURONIC ACID; HEXURONIC ACID; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; RECOMBINANT PROTEIN;

ADULT; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL ACTIVITY; BONE DEVELOPMENT; BONE TISSUE; CELL COUNT; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENCAPSULATION; EXTRACELLULAR MATRIX; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; LASER DIFFRACTION; MALE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; SUSTAINED DRUG RELEASE; TISSUE ENGINEERING; ANIMAL; BONE; BONE REGENERATION; CELL LINE; CHEMISTRY; DRUG EFFECTS; MOUSE; TISSUE SCAFFOLD; WISTAR RAT;

ALGINATES; ANIMALS; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CELL LINE; COLLAGEN; DRUG CARRIERS; DURAPATITE; GLUCURONIC ACID; HEXURONIC ACIDS; LACTIC ACID; MALE; MICE; POLYGLYCOLIC ACID; RATS, WISTAR; RECOMBINANT PROTEINS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84917690564     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.11.021     Document Type: Article

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