Nanoplex-Mediated Codelivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells

Molecular Pharmaceutics

Volumn 12, Issue 8, 2015, Pages 3032-3042

  Atluri, Keerthi ^a   Seabold, Denise ^b   Hong, Liu ^b   Elangovan, Satheesh ^b   Salem, Aliasger K ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

BMP 2; bone morphogenetic protein 2; FGF 2; fibroblast growth factor 2; human adipose derived mesenchymal stem cells; nanoplex; nonviral gene delivery; osteogenesis; pDNA; PEI; plasmid DNA; polyethylenimine

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; FIBROBLAST GROWTH FACTOR 2; NANOPARTICLE; NANOPLEX; PLASMID DNA; POLYETHYLENEIMINE; UNCLASSIFIED DRUG; BMP2 PROTEIN, HUMAN; DNA;

ADIPOCYTE; ADIPOSE DERIVED STEM CELL; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MTS ASSAY; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN SECRETION; ADMINISTRATION AND DOSAGE; BONE MARROW CELL; CELL CULTURE; CHEMISTRY; CYTOLOGY; GENE THERAPY; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; PLASMID; PROCEDURES; TISSUE ENGINEERING;

ADIPOCYTES; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CELL DIFFERENTIATION; CELLS, CULTURED; DNA; FIBROBLAST GROWTH FACTOR 2; GENETIC THERAPY; HUMANS; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PLASMIDS; POLYETHYLENEIMINE; TISSUE ENGINEERING; TRANSFECTION;

EID: 84938395508     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00297     Document Type: Article

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