The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Voets, Erik ^a   Marsman, Judith ^a   Demmers, Jeroen ^b   Beijersbergen, Roderick ^a   Wolthuis, Rob ^a,c  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN B; CYCLIN DEPENDENT KINASE 1; ISOPROTEIN; KIF4A PROTEIN, HUMAN; KINESIN; PRC1 PROTEIN, HUMAN; PROTEIN BINDING; QUINOLINE DERIVATIVE; RO 3306; SMALL INTERFERING RNA; THIAZOLE DERIVATIVE;

ALTERNATIVE RNA SPLICING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL PROLIFERATION; CHROMATID; CYTOKINESIS; DRUG EFFECTS; GENETICS; HUMAN; HUMAN CHROMOSOME; METABOLISM; MITOSIS; RNA INTERFERENCE; SPINDLE APPARATUS;

ALTERNATIVE SPLICING; ANIMALS; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CELL LINE; CELL PROLIFERATION; CHROMATIDS; CHROMOSOMES, HUMAN; CYCLIN B; CYTOKINESIS; HUMANS; KINESIN; MITOSIS; PROTEIN BINDING; PROTEIN ISOFORMS; QUINOLINES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SPINDLE APPARATUS; THIAZOLES;

EID: 84943152288     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep14798     Document Type: Article

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