Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 10, 2012, Pages 3826-3831

  Diril, M Kasim ^a   Ratnacaram, Chandrahas Koumar ^a   Padmakumar, V C ^c   Du, Tiehua ^d   Wasser, Martin ^b,d   Coppola, Vincenzo ^c,e   Tessarollo, Lino ^c   Kaldis, Philipp ^a,b  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL CANCER INSTITUTE   (United States)

^d BIOINFORMATICS INSTITUTE   (Singapore)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

Cancer; Cell cycle regulation; Knockout mice; Polyploidy

Indexed keywords

CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; DNA; PROTEIN P53;

ARTICLE; BLASTOCYST; CARCINOGENESIS; CELL CYCLE REGULATION; CELL DIVISION; CELL PROLIFERATION; DNA REPLICATION; EMBRYO DEVELOPMENT; GENE DELETION; GENE SILENCING; HUMAN; IN VIVO STUDY; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

ANIMALS; BLASTOCYST; CDC2 PROTEIN KINASE; CELL CYCLE; CELL DIVISION; DNA REPLICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, P53; GENES, RAS; LIVER REGENERATION; MICE; MICE, KNOCKOUT; MITOSIS; POLYPLOIDY; RAS PROTEINS; S PHASE; TUMOR SUPPRESSOR PROTEIN P53;

MAMMALIA; MUS;

EID: 84857956418     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115201109     Document Type: Article

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