Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited

Molecular Biology of the Cell

Volumn 22, Issue 8, 2011, Pages 1191-1206

  Potapova, Tamara A ^a,b   Sivakumar, Sushama ^c   Flynn, Jennifer N ^a   Li, Rong ^b   Gorbsky, Gary J ^a,c  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYCLIN B KINASE; CYCLIN DEPENDENT KINASE 1; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN KINASE; PROTEIN MYT1; PROTEIN WEE1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; INHIBITION KINETICS; MITOSIS; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; REGULATORY MECHANISM;

ANIMALS; CDC2 PROTEIN KINASE; CDC25 PHOSPHATASES; CELL CYCLE PROTEINS; CYCLIN B; CYCLIN-DEPENDENT KINASES; FEEDBACK, PHYSIOLOGICAL; FEMALE; G2 PHASE; GENE EXPRESSION; HELA CELLS; HUMANS; MITOSIS; NUCLEAR PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROMETAPHASE; PROTEIN KINASE INHIBITORS; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; S PHASE; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 79954625864     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-07-0599     Document Type: Article

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