The Upshot of LRRK2 Inhibition to Parkinson’s Disease Paradigm

Molecular Neurobiology

Volumn 52, Issue 3, 2015, Pages 1804-1820

  Esteves, A R ^a   G Fernandes, M ^a   Santos, D ^a   Januario C ^b   Cardoso, S M ^a,c  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

DRP1; LRRK2; Mitochondrial dynamics; Parkinson s disease; Rab7

Indexed keywords

IN 1; LEUCINE RICH REPEAT KINASE 2; PROTEIN SERINE THREONINE KINASE INHIBITOR; RAB7 PROTEIN; UNCLASSIFIED DRUG; LRRK2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

ADULT; AGED; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DAMAGE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; LRRK2 GENE; MICROTUBULE; MITOCHONDRION; PARKINSON DISEASE; PHARMACOLOGICAL BLOCKING; PROTEIN TARGETING; REGULATORY MECHANISM; FEMALE; MALE; METABOLISM; MIDDLE AGED; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN TRANSPORT; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AUTOPHAGY; FEMALE; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; NEURONS; PARKINSON DISEASE; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS;

EID: 84942836320     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8980-6     Document Type: Article

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